BRPI0509654A - cetylpyridinium chloride as antimicrobial agent in ophthalmic compositions - Google Patents

cetylpyridinium chloride as antimicrobial agent in ophthalmic compositions

Info

Publication number
BRPI0509654A
BRPI0509654A BRPI0509654-5A BRPI0509654A BRPI0509654A BR PI0509654 A BRPI0509654 A BR PI0509654A BR PI0509654 A BRPI0509654 A BR PI0509654A BR PI0509654 A BRPI0509654 A BR PI0509654A
Authority
BR
Brazil
Prior art keywords
solution
ophthalmic compositions
cetylpyridinium chloride
poly
component
Prior art date
Application number
BRPI0509654-5A
Other languages
Portuguese (pt)
Inventor
Zhi-Jian Yu
Stanley W Huth
Original Assignee
Advanced Medical Optics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Medical Optics Inc filed Critical Advanced Medical Optics Inc
Publication of BRPI0509654A publication Critical patent/BRPI0509654A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/0005—Other compounding ingredients characterised by their effect
    • C11D3/0078—Compositions for cleaning contact lenses, spectacles or lenses
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
    • A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/143—Quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/143—Quaternary ammonium compounds
    • A61L12/145—Polymeric quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D1/00—Detergent compositions based essentially on surface-active compounds; Use of these compounds as a detergent
    • C11D1/008—Polymeric surface-active agents
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/20—Organic compounds containing oxygen
    • C11D3/22—Carbohydrates or derivatives thereof
    • C11D3/222—Natural or synthetic polysaccharides, e.g. cellulose, starch, gum, alginic acid or cyclodextrin
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/26—Organic compounds containing nitrogen
    • C11D3/28—Heterocyclic compounds containing nitrogen in the ring
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/34—Organic compounds containing sulfur
    • C11D3/349—Organic compounds containing sulfur additionally containing nitrogen atoms, e.g. nitro, nitroso, amino, imino, nitrilo, nitrile groups containing compounds or their derivatives or thio urea
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/48—Medical, disinfecting agents, disinfecting, antibacterial, germicidal or antimicrobial compositions
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/34—Organic compounds containing sulfur
    • C11D3/3409—Alkyl -, alkenyl -, cycloalkyl - or terpene sulfates or sulfonates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Dentistry (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Eyeglasses (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Detergent Compositions (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pyridine Compounds (AREA)

Abstract

CLORETO DE CETILPIRIDìNIO COMO AGENTE ANTIMICROBIANO EM COMPOSIçõES OFTáLMICAS. A presente invenção refere-se a uma solução multipropósito para cuidados com lentes de contato com alta atividade antimicrobiana compreendendo, em um meio líquido aquoso, cloreto de cetilpiridínio e um tensoativo não-iónico. Em uma modalidade da invenção, o tensoativo não-iónico é um copolímero em bloco poli(oxipropileno)-poli(oxietileno). A solução, opcionalmente, pode incluir também componentes antimicrobianos adicionais, um componente tampão, um componente indutor de viscosidade, um tensoativo, taurina, propilenoglicol e/ou um componente de tonicidade. Essa solução. adicionalmente, evita perdas da integridade da membrana do tecido ocular durante o uso de lentes de contato.CETILPYRIDINE CHLORIDE AS AN ANTIMICROBIAN AGENT IN OPHTHALMIC COMPOSITIONS. The present invention relates to a multipurpose contact lens care solution with high antimicrobial activity comprising in an aqueous liquid medium cetylpyridinium chloride and a nonionic surfactant. In one embodiment of the invention, the nonionic surfactant is a poly (oxypropylene) poly (oxyethylene) block copolymer. The solution optionally may also include additional antimicrobial components, a buffer component, a viscosity inducing component, a surfactant, taurine, propylene glycol and / or a tonicity component. This solution. In addition, it avoids loss of ocular tissue membrane integrity during contact lens wear.

BRPI0509654-5A 2004-04-07 2005-03-31 cetylpyridinium chloride as antimicrobial agent in ophthalmic compositions BRPI0509654A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/820,486 US7578996B2 (en) 2004-04-07 2004-04-07 Cetylpyridinium chloride as an antimicrobial agent in ophthalmic compositions
PCT/US2005/011009 WO2005097960A1 (en) 2004-04-07 2005-03-31 Cetylpyridinium chloride as an antimicrobial agent in ophthalmic compositions

Publications (1)

Publication Number Publication Date
BRPI0509654A true BRPI0509654A (en) 2007-10-09

Family

ID=34972927

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0509654-5A BRPI0509654A (en) 2004-04-07 2005-03-31 cetylpyridinium chloride as antimicrobial agent in ophthalmic compositions

Country Status (11)

Country Link
US (2) US7578996B2 (en)
EP (1) EP1733014B1 (en)
JP (1) JP2007532953A (en)
CN (1) CN1942571B (en)
AT (1) ATE426655T1 (en)
AU (1) AU2005230851B2 (en)
BR (1) BRPI0509654A (en)
CA (1) CA2562546C (en)
DE (1) DE602005013498D1 (en)
ES (2) ES2321214T3 (en)
WO (1) WO2005097960A1 (en)

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US20070264226A1 (en) * 2006-05-10 2007-11-15 Karagoezian Hampar L Synergistically enhanced disinfecting solutions
US8759321B2 (en) * 2007-06-13 2014-06-24 Bausch & Lomb Incorporated Ophthalmic composition with hyaluronic acid and polymeric biguanide
TWI419719B (en) * 2007-08-31 2013-12-21 Novartis Ag Contact lens products
US9096819B2 (en) 2008-01-31 2015-08-04 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and an anionic biopolymer
US8119112B2 (en) * 2008-01-31 2012-02-21 Bausch & Lomb Incorporated Ophthalmic compositions with an amphoteric surfactant and hyaluronic acid
US20110046033A1 (en) 2008-01-31 2011-02-24 Jinzhong Zhang Multipurpose Lens Care Solution with Benefits to Corneal Epithelial Barrier Function
US20100286010A1 (en) * 2008-09-03 2010-11-11 Erning Xia Ophthalmic Compositions with Hyaluronic Acid
US9125405B2 (en) * 2008-10-28 2015-09-08 Bausch & Lomb Incorporated Contact lens solution with a tertiary amine oxide
WO2012080918A2 (en) * 2010-12-14 2012-06-21 Ecolab Usa Inc. Wear resistant antimicrobial compositions and methods of use
US9872843B2 (en) * 2011-10-08 2018-01-23 Next Science, Llc Antimicrobial compositions and methods employing same
CA2854742C (en) * 2011-11-06 2021-03-09 Nbip, Llc Antimicrobial compositions comprising biocide, ph buffer and surfactant
CN102552914A (en) * 2012-01-31 2012-07-11 江西科伦药业有限公司 Composition capable of simultaneously adjusting pH value and osmotic pressure and preparation method thereof
US8324171B1 (en) 2012-02-06 2012-12-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
US8664180B2 (en) 2012-02-06 2014-03-04 Bausch & Lomb Incorporated Ophthalmic compositions containing diglycine
CN102835398A (en) * 2012-09-28 2012-12-26 山东潍坊润丰化工有限公司 Method for preparing clopyralid choline aqueous solution and active compound
AU2015236281B2 (en) * 2014-03-24 2017-10-05 S.C. Johnson & Son, Inc. Corrosive ingredient (s) - containing compositions having reduced toxicity and method of obtaining
GB201621050D0 (en) * 2016-12-12 2017-01-25 Provita Eurotech Ltd Antimicrobial compositions
AU2019261437A1 (en) * 2018-04-27 2020-12-17 Allergan, Inc. Sodium chlorite compositions with enhanced anti-microbial efficacy and reduced toxicity
JP7253128B2 (en) * 2018-06-13 2023-04-06 京都バイオファーマ製薬株式会社 External composition containing depsipeptide antibiotic
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EP3852608A4 (en) * 2018-09-21 2022-09-28 Aufbau Medical Innovations Limited Compositions and methods for glaucoma
AU2020395914A1 (en) * 2019-12-05 2022-05-19 Cis Pharma Ag High hyaluronate multi-purpose disinfection solutions for ophthalmic applications

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Also Published As

Publication number Publication date
ATE426655T1 (en) 2009-04-15
WO2005097960A1 (en) 2005-10-20
US7578996B2 (en) 2009-08-25
EP1733014B1 (en) 2009-03-25
CN1942571B (en) 2012-02-15
AU2005230851B2 (en) 2010-12-23
CA2562546C (en) 2013-11-19
CN1942571A (en) 2007-04-04
DE602005013498D1 (en) 2009-05-07
JP2007532953A (en) 2007-11-15
ES2321214T3 (en) 2009-06-03
CA2562546A1 (en) 2005-10-20
EP1733014A1 (en) 2006-12-20
US20090318512A1 (en) 2009-12-24
ES2323827A1 (en) 2009-07-24
AU2005230851A1 (en) 2005-10-20
US20050226841A1 (en) 2005-10-13
ES2323827B1 (en) 2010-04-19

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]