BRPI0506795A - microorganismo, vetor e processo para preparação de l-aminoácidos a partir de d-aminoácidos - Google Patents

microorganismo, vetor e processo para preparação de l-aminoácidos a partir de d-aminoácidos

Info

Publication number
BRPI0506795A
BRPI0506795A BRPI0506795-2A BRPI0506795A BRPI0506795A BR PI0506795 A BRPI0506795 A BR PI0506795A BR PI0506795 A BRPI0506795 A BR PI0506795A BR PI0506795 A BRPI0506795 A BR PI0506795A
Authority
BR
Brazil
Prior art keywords
amino acids
preparing
microorganism
vector
amino acid
Prior art date
Application number
BRPI0506795-2A
Other languages
English (en)
Inventor
Werner Hummel
Birgit Geueke
Steffen Osswald
Christoph Weckbecker
Klaus Huthmacher
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Publication of BRPI0506795A publication Critical patent/BRPI0506795A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0016—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0014—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4)
    • C12N9/0022—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on the CH-NH2 group of donors (1.4) with oxygen as acceptor (1.4.3)
    • C12N9/0024—D-Amino acid oxidase (1.4.3.3)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0065—Oxidoreductases (1.) acting on hydrogen peroxide as acceptor (1.11)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine

Abstract

MICROORGANISMO, VETOR E PROCESSO PARA PREPARAçãO DE L-AMINOáCIDOS A PARTIR DE D-AMINOáCIDOS. A presente invenção refere-se a microorganismos recombinantes, que em relação ao organismo de partida apresentam aumentada concentração ou atividade de uma oxidase de aminoácido D, de uma desidrogenase de aminoácido, de uma enzima regeneradora de co-substrato NADH e eventualmente de uma catalase e a um processo para preparação de aminoácidos L a partir de aminoácidos D com emprego destes micoorganismos.
BRPI0506795-2A 2004-02-19 2005-01-27 microorganismo, vetor e processo para preparação de l-aminoácidos a partir de d-aminoácidos BRPI0506795A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102004008445A DE102004008445A1 (de) 2004-02-19 2004-02-19 Verfahren zur Herstellung von L-Aminosäuren aus D-Aminosäuren
PCT/EP2005/000768 WO2005090590A1 (de) 2004-02-19 2005-01-27 Verfahren zur herstellung von l-aminosäuren aus d-aminosäuren

Publications (1)

Publication Number Publication Date
BRPI0506795A true BRPI0506795A (pt) 2007-05-22

Family

ID=34832887

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0506795-2A BRPI0506795A (pt) 2004-02-19 2005-01-27 microorganismo, vetor e processo para preparação de l-aminoácidos a partir de d-aminoácidos

Country Status (8)

Country Link
US (1) US7217544B2 (pt)
EP (1) EP1716241A1 (pt)
JP (1) JP2007522810A (pt)
CN (2) CN103834607A (pt)
BR (1) BRPI0506795A (pt)
DE (1) DE102004008445A1 (pt)
RU (1) RU2006133266A (pt)
WO (1) WO2005090590A1 (pt)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090209012A1 (en) * 2005-06-09 2009-08-20 Daicel Chemical Industries, Ltd. Method for producing l-amino acids
US8227228B2 (en) 2005-08-02 2012-07-24 Kaneka Corporation D-amino acid oxidase, and method for production of L-amino acid, 2-oxo acid, or cyclic imine
BRPI0715584B8 (pt) * 2006-07-19 2017-02-21 Ajinomoto Kk método para produzir um l-aminoácido
JP5005293B2 (ja) * 2006-08-22 2012-08-22 株式会社カネカ Ｄ−アミノ酸オキシダーゼ、およびｌ−アミノ酸、２−オキソ酸、又は環状イミンの製造方法。
EP2072622A4 (en) * 2006-10-12 2012-01-25 Kaneka Corp PROCESS FOR PRODUCTION OF L-AMINO ACID
WO2008080138A1 (en) * 2006-12-22 2008-07-03 Richmond Chemical Corporation Stereoinversion of amino acids
JPWO2010067578A1 (ja) * 2008-12-09 2012-05-17 株式会社カネカ 新規なアミノ酸脱水素酵素、およびｌ−アミノ酸、２−オキソ酸、又はｄ−アミノ酸の製造方法
CN102174632A (zh) * 2009-05-19 2011-09-07 重庆邮电大学 一种非天然l-氨基酸的生物催化去消旋化制备方法
US9080192B2 (en) 2010-02-10 2015-07-14 Codexis, Inc. Processes using amino acid dehydrogenases and ketoreductase-based cofactor regenerating system
CN104557911B (zh) * 2013-10-17 2016-08-31 苏州同力生物医药有限公司 一种左旋吡喹酮的制备方法
KR102250342B1 (ko) * 2014-04-30 2021-05-10 에보닉 오퍼레이션스 게엠베하 호알칼리성 박테리아를 사용하는 l-아미노산 생산 방법
CN106795511B (zh) 2014-07-11 2020-02-11 住友化学株式会社 氧化酶、编码该酶的多核苷酸、以及它们的应用
EP3423585A1 (en) 2016-03-02 2019-01-09 Agrimetis, LLC Methods for making l-glufosinate
CN106520651A (zh) * 2016-11-08 2017-03-22 江南大学 一种利用酶法转化生产l‑正缬氨酸的方法
CN107502647B (zh) * 2017-09-15 2020-12-15 浙江大学 一种生物酶法去消旋化制备l-草铵膦的方法
CN109971802B (zh) * 2017-12-28 2023-04-07 苏州同力生物医药有限公司 一种酶法拆分制备(s)-1,2,3,4-四氢异喹啉-1-甲酸及其衍生物的方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19606494A1 (de) 1996-02-22 1997-08-28 Degussa Enzym mit LeuDH-Aktivität, dafür codierende Nukleotid-Sequenz und Verfahren zur Herstellung des Enzyms
ES2109194B1 (es) * 1996-04-22 1998-07-16 Antibioticos Sa Un procedimiento para producir la enzima d-aminoacido oxidasa de rhodotorula gracilis en celulas hospedantes.
US7981844B2 (en) * 2001-06-21 2011-07-19 Verenium Corporation Methods for the manufacture of pure single enantiomer compounds and for selecting enantioselective enzymes
EP1375649B1 (en) * 2002-06-19 2012-03-07 Evonik Degussa GmbH D-amino acid oxidase from Arthrobacter protophormiae
DE10240603A1 (de) 2002-09-03 2004-03-11 Degussa Ag Verwendung von Malat-Dehydrogenase zur NADH-Regenerierung

Also Published As

Publication number Publication date
US20060063238A1 (en) 2006-03-23
RU2006133266A (ru) 2008-03-27
WO2005090590A1 (de) 2005-09-29
DE102004008445A1 (de) 2005-09-08
CN1922328A (zh) 2007-02-28
CN103834607A (zh) 2014-06-04
EP1716241A1 (de) 2006-11-02
US7217544B2 (en) 2007-05-15
JP2007522810A (ja) 2007-08-16

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B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette]