BRPI0416843A8 - dímeros de triazina, composição compreendendo os mesmos, seus usos e processos de remoção e purificação de anticorpos - Google Patents

dímeros de triazina, composição compreendendo os mesmos, seus usos e processos de remoção e purificação de anticorpos

Info

Publication number
BRPI0416843A8
BRPI0416843A8 BRPI0416843A BRPI0416843A BRPI0416843A8 BR PI0416843 A8 BRPI0416843 A8 BR PI0416843A8 BR PI0416843 A BRPI0416843 A BR PI0416843A BR PI0416843 A BRPI0416843 A BR PI0416843A BR PI0416843 A8 BRPI0416843 A8 BR PI0416843A8
Authority
BR
Brazil
Prior art keywords
autoimmune diseases
compounds
purification
composition
methods
Prior art date
Application number
BRPI0416843A
Other languages
English (en)
Portuguese (pt)
Inventor
Ezzitouni Abdallah
D Cameron Alan
Zacharie Boulos
Grouix Brigitte
Penney Christopher
Fortin Daniel
Bienvenu Jean-François
Duceppe Jean-Simon
Houde Karine
Gagnon Lyne
Moreau Nancie
Wilb Nicole
D Abbott Shaun
Original Assignee
Prometic Biosciences Inc
Prometic Pharma Smt Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Prometic Biosciences Inc, Prometic Pharma Smt Ltd filed Critical Prometic Biosciences Inc
Publication of BRPI0416843A publication Critical patent/BRPI0416843A/pt
Publication of BRPI0416843A8 publication Critical patent/BRPI0416843A8/pt

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/12Drugs for disorders of the urinary system of the kidneys
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D251/00Heterocyclic compounds containing 1,3,5-triazine rings
    • C07D251/02Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings
    • C07D251/12Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D251/26Heterocyclic compounds containing 1,3,5-triazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hetero atoms directly attached to ring carbon atoms
    • C07D251/40Nitrogen atoms
    • C07D251/54Three nitrogen atoms
    • C07D251/70Other substituted melamines

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Transplantation (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
BRPI0416843A 2003-11-24 2004-11-22 dímeros de triazina, composição compreendendo os mesmos, seus usos e processos de remoção e purificação de anticorpos BRPI0416843A8 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52402103P 2003-11-24 2003-11-24
PCT/CA2004/002003 WO2005049607A1 (en) 2003-11-24 2004-11-22 Triazine dimers for the treatment of autoimmune diseases

Publications (2)

Publication Number Publication Date
BRPI0416843A BRPI0416843A (pt) 2007-02-13
BRPI0416843A8 true BRPI0416843A8 (pt) 2019-01-02

Family

ID=34619624

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0416843A BRPI0416843A8 (pt) 2003-11-24 2004-11-22 dímeros de triazina, composição compreendendo os mesmos, seus usos e processos de remoção e purificação de anticorpos

Country Status (13)

Country Link
US (1) US7683061B2 (https=)
EP (1) EP1687297B1 (https=)
JP (1) JP5160788B2 (https=)
AU (1) AU2004291186B2 (https=)
BR (1) BRPI0416843A8 (https=)
CA (1) CA2554635C (https=)
DK (1) DK1687297T3 (https=)
ES (1) ES2501169T3 (https=)
IL (1) IL175814A0 (https=)
MX (1) MXPA06005879A (https=)
PL (1) PL1687297T3 (https=)
PT (1) PT1687297E (https=)
WO (1) WO2005049607A1 (https=)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006203826A1 (en) 2005-01-07 2006-07-13 Emory University CXCR4 antagonists for the treatment of HIV infection
EP1838320B1 (en) * 2005-01-07 2014-07-16 Emory University Cxcr4 antagonists for the treatment of medical disorders
CN101180061A (zh) 2005-05-19 2008-05-14 普罗米蒂克生物科学公司 化合物、含有此类化合物的组合物、和治疗转移性黑素瘤和其它癌症的方法
BRPI0709778B1 (pt) * 2006-05-08 2017-12-19 Ciba Holding Inc. Triazin derivatives, processes for their preparation, cosmetic composition, and uv absorbing dispersion
US8080659B2 (en) * 2006-07-11 2011-12-20 Emory University CXCR4 antagonists including diazine and triazine structures for the treatment of medical disorders
US9510982B2 (en) 2010-01-13 2016-12-06 Ferno-Washington, Inc. Powered roll-in cots
US8927547B2 (en) 2010-05-21 2015-01-06 Noviga Research Ab Pyrimidine derivatives
DK2688883T3 (en) 2011-03-24 2016-09-05 Noviga Res Ab pyrimidine
GB201119358D0 (en) * 2011-11-10 2011-12-21 Lewi Paulus J Disubstituted triazine dimers for treatment and/or prevention of infectious diseases
USD751000S1 (en) 2013-06-17 2016-03-08 Ferno-Washington, Inc. Control panel of a patient transport device having surface ornamentation
KR20160087834A (ko) 2013-11-15 2016-07-22 페르노-와싱턴, 인코포레이티드. 자체-작동 코트들
CN108078690A (zh) 2014-04-04 2018-05-29 费诺-华盛顿公司 用于自动地铰接床的方法和系统

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2392607A (en) * 1946-01-08 Preparation of mono-aryl melamines
US2544071A (en) * 1951-03-06 Diethylenetrimelamine and method
GB122458A (en) * 1918-01-22 1919-01-22 Regent Carriage Company Ltd Improvements in or relating to Strainers and like Devices for use on Aircraft.
BE707403A (https=) * 1966-12-03 1968-04-16
JPS4925501B1 (https=) * 1969-07-21 1974-07-01
IT1060458B (it) * 1975-12-18 1982-08-20 Chimosa Chimica Organica Spa Composti piperidil triazinici adatti per la stabilizzazione di polimeri sintetici e procedimento per la loro preparazione
US4269832A (en) * 1978-04-12 1981-05-26 American Cyanamid Company Method of treating arthritic disease
GB2053926B (en) * 1979-07-20 1983-02-23 Atkinson A Albumin extraction by affinity chromatography
FR2518106B1 (fr) * 1981-12-11 1986-12-05 Sandoz Sa Procede de teinture et d'impression de substrats organiques a l'aide de colorants directs bisazoiques
JPS58179263A (ja) * 1982-04-13 1983-10-20 Ube Ind Ltd 難燃性ポリアミド組成物
EP0101411B1 (de) * 1982-08-11 1989-01-25 Ciba-Geigy Ag Verfahren zur chemischen Bindung von Stabilisatoren an Polymere
DE3440777C2 (de) * 1983-11-14 1998-09-03 Clariant Finance Bvi Ltd Neue sulfonsäuregruppenhaltige, basische Azoverbindungen, deren Herstellung und Verwendung als Farbstoffe
JPS60260655A (ja) * 1984-06-06 1985-12-23 Mitsubishi Chem Ind Ltd ジスアゾ化合物及びセルロース繊維類用ジスアゾ反応性染料
JPS61225232A (ja) * 1985-03-29 1986-10-07 Adeka Argus Chem Co Ltd ポリオレフイン樹脂組成物
DE3518375C1 (de) * 1985-05-22 1986-07-17 Degussa Ag, 6000 Frankfurt Oxymethylencopolymerisat-Formmassen mit verminderter Formaldehyd-Emission bei der thermoplastischen Verarbeitung
JPS61272270A (ja) * 1985-05-28 1986-12-02 Mitsubishi Chem Ind Ltd ジスアゾ系化合物
JPH0619046B2 (ja) * 1985-12-06 1994-03-16 三菱化成株式会社 ジスアゾ化合物およびそれを含有する染料組成物
JPH07109526B2 (ja) * 1987-03-05 1995-11-22 日本化薬株式会社 電子写真用トナ−
JPH01154140A (ja) * 1987-12-11 1989-06-16 Fuji Photo Film Co Ltd 感光性マイクロカプセル及び感光材料
EP0310139A3 (en) * 1987-10-02 1990-10-31 Fuji Photo Film Co., Ltd. Light-sensitive microcapsule and light-sensitive material employing the same
GB8801486D0 (en) * 1988-01-22 1988-02-24 Ici Plc Water-soluble dye
DE58907811D1 (de) * 1988-03-16 1994-07-14 Ciba Geigy Reaktivfarbstoffe, Verfahren zu deren Herstellung und deren Verwendung.
US4972010A (en) * 1988-09-21 1990-11-20 Uniroyal Chemical Company, Inc. Substituted triazines
GB9016449D0 (en) * 1990-07-26 1990-09-12 Ici Plc Anionic compounds
US5374301A (en) * 1990-07-26 1994-12-20 Zeneca Limited Inks suitable for use in ink jet printing
GB9016448D0 (en) * 1990-07-26 1990-09-12 Ici Plc Anionic compounds
JPH04295860A (ja) * 1991-03-25 1992-10-20 Ricoh Co Ltd 画像形成方法
IT1252292B (it) * 1991-11-14 1995-06-08 Mini Ricerca Scient Tecnolog Policondensati melamminici
IT1252291B (it) * 1991-11-14 1995-06-08 Mini Ricerca Scient Tecnolog Composizioni polimeriche autoestinguenti
GB9220964D0 (en) * 1991-11-15 1992-11-18 Ici Plc Anionic compounds
CH684948A5 (de) * 1992-05-13 1995-02-15 Sandoz Ag Basische sulfogruppenhaltige Disazoverbindungen.
JP3210095B2 (ja) * 1992-10-13 2001-09-17 ハッコールケミカル株式会社 有機白色顔料
JPH06329933A (ja) * 1993-05-19 1994-11-29 Canon Inc 染料化合物、これを含有するインク、このインクを用いる記録方法、及び、かかるインクを用いた機器
US5631352A (en) * 1994-06-20 1997-05-20 Ciba-Geigy Corporation Azodyes containing a bridge member based on diamino-substituted triazines
JPH0895281A (ja) * 1994-09-29 1996-04-12 Canon Inc 記録紙及びこれを用いた画像形成方法
JPH10291365A (ja) * 1997-04-21 1998-11-04 Fuji Xerox Co Ltd 多色インクセット及びインクジェット記録方法
JPH1148609A (ja) * 1997-08-04 1999-02-23 Fuji Xerox Co Ltd 画像記録方法及び画像記録装置
ES2188002T3 (es) * 1997-09-27 2003-06-16 Clariant Finance Bvi Ltd Compuestos monoazo punteados.
US6482255B1 (en) * 1997-10-24 2002-11-19 Avecia Limited Disazodyes for ink jet printing
GB9820176D0 (en) * 1998-09-16 1998-11-11 Zeneca Ltd Inks
GB9929318D0 (en) * 1999-12-10 2000-02-02 Prometic Biosciences Limited Macrocyclic compounds and their use
US6153365A (en) * 1999-12-16 2000-11-28 Eastman Kodak Company Photographic processing compositions containing stain reducing agent
EP1246823A1 (en) * 1999-12-28 2002-10-09 Pharmacopeia, Inc. Pyrimidine and triazine kinase inhibitors
JP5142432B2 (ja) * 2000-08-08 2013-02-13 キヤノン株式会社 蛍光インク、インクジェット記録方法、記録ユニット、インクカートリッジ、インクジェット記録装置、蛍光増強方法及び蛍光の長寿命化方法
US6881454B2 (en) * 2000-12-14 2005-04-19 Fuji Photo Film Co., Ltd. Substantially colorless and optically anisotropic material
JP4139558B2 (ja) * 2000-12-27 2008-08-27 富士フイルム株式会社 ビストリアジニルアリーレンジアミン誘導体とジアミノスチルベン誘導体とを含有する写真処理組成物及び画像形成方法
JP2002275397A (ja) * 2001-03-16 2002-09-25 Canon Inc インクセット、それを用いたインクジェット記録方法、記録ユニット、インクカートリッジ、及びインクジェット記録装置
GB2379706A (en) * 2001-09-18 2003-03-19 Procorp Designs Ltd Sliding sash window assembly

Also Published As

Publication number Publication date
CA2554635C (en) 2013-06-18
WO2005049607B1 (en) 2005-07-14
JP5160788B2 (ja) 2013-03-13
CA2554635A1 (en) 2005-06-02
PL1687297T3 (pl) 2014-11-28
PT1687297E (pt) 2014-09-18
AU2004291186B2 (en) 2012-01-19
WO2005049607A1 (en) 2005-06-02
ES2501169T3 (es) 2014-10-01
IL175814A0 (en) 2006-10-05
MXPA06005879A (es) 2007-01-26
US20070149528A1 (en) 2007-06-28
EP1687297B1 (en) 2014-06-18
BRPI0416843A (pt) 2007-02-13
DK1687297T3 (da) 2014-09-22
US7683061B2 (en) 2010-03-23
EP1687297A4 (en) 2009-04-22
EP1687297A1 (en) 2006-08-09
JP2007512259A (ja) 2007-05-17
AU2004291186A1 (en) 2005-06-02

Similar Documents

Publication Publication Date Title
BRPI0416843A8 (pt) dímeros de triazina, composição compreendendo os mesmos, seus usos e processos de remoção e purificação de anticorpos
Valenzuela et al. Purification, cloning, and expression of a novel salivary anticomplement protein from the tick, Ixodes scapularis
BRPI0507489A (pt) anticorpos humanos de anti-cd38 e para os seus usos
Sawada et al. Identification of a vesicular nucleotide transporter
AR124547A1 (es) Degradadores de irak y sus usos
BR0312575A (pt) Moduladores do receptor de glicocorticóides
Loughnan et al. Identification of a novel class of nicotinic receptor antagonists: dimeric conotoxins VxXIIA, VxXIIB, and VxXIIC from Conus vexillum
EA200801509A1 (ru) Человеческие моноклональные антитела к протеинтирозинкиназе 7 ( ptk7) и способы применения антител против ptk7
BRPI0413018A (pt) composto, e, método para tratar ou prevenir doenças auto-imunes e/ou um ou mais sintomas associados com eles
BR0113637A (pt) Composto, processo para a preparação desse composto, composição farmacêutica que compreende o mesmo, utilização do composto, processo para o tratamento e/ou profilaxia de enfermidade que estão associadas com a atividade de receptor melanocortin-4
CR8095A (es) Anticuerpos humanizados que reconocen el cuerpo beta amiloideo
BRPI0414062A (pt) uso de ciclosporinas midificadas para o tratamento de distúrbios por hcv
NO308029B1 (no) Inhibitorer av <beta>-amyloidproteinproduksjon og farmasøytisk preparat inneholdende disse
BR0314721A (pt) Compostos tricìclicos úteis para tratamento de distúrbios inflamatórios e alérgicos, processo para sua preparação e composições farmacêuticas contendo-os
MX361717B (es) Diacilhidrazinas que contienen boro.
GT200200188A (es) Preparacion y uso de derivados de imidazol para el tratamiento de la obesidad
BRPI0507236A (pt) método para o tratamento ou profilaxia de uma condição, e, composto
ECSP044935A (es) Inhibidores de la dipeptidil peptidasa beta-amino heterocíclica para el tratamiento o la prevención de la diabetes
ECSP056142A (es) Formulaciones de anticuerpos y proteínas de alta concentración
ECSP066669A (es) Indoles, 1h-indazoles, 1,2-benzisoxazoles, y 1,2-benzisotiazoles, y preparación y usos de los mismos
BR0309933A (pt) (s)-4-amino-5-cloro-2-metoxi-n-[1-[1-(2-tetraidrofurilc arbonil)-4-piperidinil-metil]-4-piperidinil] benzamida, processo para sua preparação, composição farmacêutica contendo o mesmo e intermediários obtidos desta forma
BR0315008A (pt) Compostos neurologicamente ativos
BR0112272A (pt) Anticorpo monoclonal anti-trkc agonista, cadeia pesada de anticorpo anti-trkc, cadeia leve de anticorpo anti-trkc, cadeia pesada de anticorpo anti-trkc murino, cadeia pesada de anticorpo anti-trkc humano, anticorpo agonista anti-trkc murino, anticorpo agonista anti-trkc humano, moléculas de ácido nucléico isolado, moléculas de ácido nucléico, vetor, linhagens de células hospedeiras, linhagens de células de hibridoma, célula hospedeira, polipeptìdeo, composição farmacêutica, método para o tratamento de neuropatia ou doença neurodegenerativa ou reparo de uma célula nervosa lesionada, método para aumentar a proliferação, manutenção ou regeneração de neurÈnios periféricos, método para o tratamento de doença ou condição que envolve a degeneração celular em um paciente mamìfero, método de indução de angiogênese, método de fabricação de um anticorpo anti-trkc, usos de um anticorpo
GB0117326D0 (en) Napthoquinone-type inhibitors of protein aggregation
BR0308146A (pt) Composto, composição farmacêutica, uso de um composto, e, processo para a preparação de um composto

Legal Events

Date Code Title Description
B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]
B25A Requested transfer of rights approved

Owner name: PROMETIC PHARMA SMT LIMITED (CA)

B06G Technical and formal requirements: other requirements [chapter 6.7 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL