BRPI0409456A - métodos para o tratamento e/ou prevenção de doenças ligadas ao acúmulo de triglicerìdeos em tecidos e sangue, de doenças ligadas a uma falta de equilìbrio de colesterol em prejuìzo de colesterol hdl em tecidos e sangue, métodos de tratamento para diminuir os nìveis no sangue de triglicerìdeos, para equilibrar o nìvel no sangue e/ou tecidos de colesterol total em favor de colesterol hdl, para abaixar os nìveis de triglicerìdeo no fìgado, método para o tratamento ou prevenção de uma condição obesa, método de tratamento para a redução ou inibição do ganho de gordura corporal, método para aliviar a resistência ou restaurar a sensibilidade a insulina, uso de ácido beta-aminoisobutìrico, derivado, prodroga, metabólito ou complexo do mesmo, composição farmacêutica, composição nutricional, e, método para produzir redução de massa de gordura - Google Patents

métodos para o tratamento e/ou prevenção de doenças ligadas ao acúmulo de triglicerìdeos em tecidos e sangue, de doenças ligadas a uma falta de equilìbrio de colesterol em prejuìzo de colesterol hdl em tecidos e sangue, métodos de tratamento para diminuir os nìveis no sangue de triglicerìdeos, para equilibrar o nìvel no sangue e/ou tecidos de colesterol total em favor de colesterol hdl, para abaixar os nìveis de triglicerìdeo no fìgado, método para o tratamento ou prevenção de uma condição obesa, método de tratamento para a redução ou inibição do ganho de gordura corporal, método para aliviar a resistência ou restaurar a sensibilidade a insulina, uso de ácido beta-aminoisobutìrico, derivado, prodroga, metabólito ou complexo do mesmo, composição farmacêutica, composição nutricional, e, método para produzir redução de massa de gordura

Info

Publication number
BRPI0409456A
BRPI0409456A BRPI0409456-5A BRPI0409456A BRPI0409456A BR PI0409456 A BRPI0409456 A BR PI0409456A BR PI0409456 A BRPI0409456 A BR PI0409456A BR PI0409456 A BRPI0409456 A BR PI0409456A
Authority
BR
Brazil
Prior art keywords
blood
cholesterol
treatment
triglycerides
balance
Prior art date
Application number
BRPI0409456-5A
Other languages
English (en)
Portuguese (pt)
Inventor
Bernard Fromenty
Caroline Maisonneuve
Anissa Igoudjil
Philippe Letteron
Karima Begriche
Original Assignee
Inst Nat Sante Rech Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med
Publication of BRPI0409456A publication Critical patent/BRPI0409456A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23KFODDER
    • A23K20/00Accessory food factors for animal feeding-stuffs
    • A23K20/10Organic substances
    • A23K20/142Amino acids; Derivatives thereof
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/17Amino acids, peptides or proteins
    • A23L33/175Amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/16Amides, e.g. hydroxamic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Polymers & Plastics (AREA)
  • Emergency Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Food Science & Technology (AREA)
  • Obesity (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Endocrinology (AREA)
  • Vascular Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0409456-5A 2003-04-18 2004-04-15 métodos para o tratamento e/ou prevenção de doenças ligadas ao acúmulo de triglicerìdeos em tecidos e sangue, de doenças ligadas a uma falta de equilìbrio de colesterol em prejuìzo de colesterol hdl em tecidos e sangue, métodos de tratamento para diminuir os nìveis no sangue de triglicerìdeos, para equilibrar o nìvel no sangue e/ou tecidos de colesterol total em favor de colesterol hdl, para abaixar os nìveis de triglicerìdeo no fìgado, método para o tratamento ou prevenção de uma condição obesa, método de tratamento para a redução ou inibição do ganho de gordura corporal, método para aliviar a resistência ou restaurar a sensibilidade a insulina, uso de ácido beta-aminoisobutìrico, derivado, prodroga, metabólito ou complexo do mesmo, composição farmacêutica, composição nutricional, e, método para produzir redução de massa de gordura BRPI0409456A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/IB2003/001463 WO2004091598A1 (en) 2003-04-18 2003-04-18 Use of beta-aminoisobutyric acid for the treatment of diseases linked to the accumulation of triglycerides and cholesterol
PCT/IB2004/001166 WO2004091599A1 (en) 2003-04-18 2004-04-15 Method for the treatment of diseases linked to an accumulation of triglycerides and cholesterol

Publications (1)

Publication Number Publication Date
BRPI0409456A true BRPI0409456A (pt) 2006-04-18

Family

ID=33187198

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0409456-5A BRPI0409456A (pt) 2003-04-18 2004-04-15 métodos para o tratamento e/ou prevenção de doenças ligadas ao acúmulo de triglicerìdeos em tecidos e sangue, de doenças ligadas a uma falta de equilìbrio de colesterol em prejuìzo de colesterol hdl em tecidos e sangue, métodos de tratamento para diminuir os nìveis no sangue de triglicerìdeos, para equilibrar o nìvel no sangue e/ou tecidos de colesterol total em favor de colesterol hdl, para abaixar os nìveis de triglicerìdeo no fìgado, método para o tratamento ou prevenção de uma condição obesa, método de tratamento para a redução ou inibição do ganho de gordura corporal, método para aliviar a resistência ou restaurar a sensibilidade a insulina, uso de ácido beta-aminoisobutìrico, derivado, prodroga, metabólito ou complexo do mesmo, composição farmacêutica, composição nutricional, e, método para produzir redução de massa de gordura

Country Status (7)

Country Link
US (1) US20060167098A1 (enExample)
EP (1) EP1615630A1 (enExample)
JP (1) JP2006523672A (enExample)
AU (1) AU2003226582A1 (enExample)
BR (1) BRPI0409456A (enExample)
CA (1) CA2526899A1 (enExample)
WO (2) WO2004091598A1 (enExample)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8367072B2 (en) * 2006-12-08 2013-02-05 Polifenoles Naturales, S.L. Composition for treating obesity and method of using the same
JP5911503B2 (ja) * 2010-11-15 2016-04-27 ラモット・アット・テル・アビブ・ユニバーシテイ・リミテッドRamot At Tel Aviv University Ltd. アミロイド線維形成関連状態を処置するためのジペプチドアナログ
CN105250256A (zh) * 2015-10-16 2016-01-20 南京医科大学 β-氨基异丁酸在制备抗糖尿病药物中的应用
US10869923B2 (en) * 2016-03-30 2020-12-22 Microbio Co. Ltd. Combined cancer therapy with immune checkpoint modulators and fermentation products by symbiotic microbiota
JP2019131488A (ja) * 2018-01-29 2019-08-08 静岡県公立大学法人 Vcam−1発現抑制剤、mcp−1発現抑制剤、炎症性疾患改善用組成物、加工食品又は飲料
WO2021055564A1 (en) * 2019-09-17 2021-03-25 Yale University Methods of treating phosphate concentration disorders with l-baiba
EP4297742A4 (en) * 2021-04-14 2024-10-09 Nanjing Nutrabuilding Bio-Tech Co., Ltd. COMPOSITIONS AND METHODS FOR PROMOTING GLYCOGEN SYNTHASE ACTIVITY AND INCREASING GLYCOGEN STORAGE CAPACITY
WO2022268049A1 (en) * 2021-06-22 2022-12-29 Nanjing Nutrabuilding Bio-Tech Co., Ltd Administration of baiba to increase benefit of losing weight of intermittent fasting
CN115606809A (zh) * 2021-10-08 2023-01-17 南京纽邦生物科技有限公司 通过施用β-氨基异丁酸模拟热量限制的生物学益处的方法和组合物
CN116059195A (zh) * 2022-01-28 2023-05-05 南京纽邦生物科技有限公司 用于提高运动表现或预防或缓解疲劳的组合物和方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4453941A (en) * 1980-12-29 1984-06-12 Board Of Overseers Of Goshen College Composition and process for producing pigmentation in hair or skin
DE4115468A1 (de) * 1991-05-11 1992-11-12 Behringwerke Ag Amidinophenylalaninderivate, verfahren zu deren herstellung, deren verwendung und diese enthaltende mittel als antikoagulantien
FR2701948B1 (fr) * 1993-02-22 1996-07-26 Exsymol Sa Produit de couplage de l'histamine ou l'histamine méthyl-substituée et d'un acide aminé, procédé de préparation et applications thérapeutiques, cosmétologiques et agroalimentaires.
JPH07101984A (ja) * 1993-09-30 1995-04-18 Suntory Ltd ペプチド誘導体
JPH107553A (ja) * 1996-03-21 1998-01-13 Toutoushiyu Seizo Kk 生体内ラジカル消去剤及び抗潰瘍剤

Also Published As

Publication number Publication date
WO2004091599A1 (en) 2004-10-28
AU2003226582A1 (en) 2004-11-04
EP1615630A1 (en) 2006-01-18
WO2004091598A1 (en) 2004-10-28
US20060167098A1 (en) 2006-07-27
CA2526899A1 (en) 2004-10-28
JP2006523672A (ja) 2006-10-19

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Legal Events

Date Code Title Description
B11A Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing
B11Y Definitive dismissal acc. article 33 of ipl - extension of time limit for request of examination expired
B15K Others concerning applications: alteration of classification

Ipc: A61K 31/22 (2006.01), A23K 20/142 (2016.01), A23L