BR9914051A - Métodos para administração de antibióticos - Google Patents

Métodos para administração de antibióticos

Info

Publication number
BR9914051A
BR9914051A BR9914051-9A BR9914051A BR9914051A BR 9914051 A BR9914051 A BR 9914051A BR 9914051 A BR9914051 A BR 9914051A BR 9914051 A BR9914051 A BR 9914051A
Authority
BR
Brazil
Prior art keywords
administering
daptomycin
methods
muscle toxicity
skeletal muscle
Prior art date
Application number
BR9914051-9A
Other languages
English (en)
Inventor
Frederick B Oleson Jr
Francis P Tally
Original Assignee
Cubist Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26798675&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9914051(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Cubist Pharm Inc filed Critical Cubist Pharm Inc
Publication of BR9914051A publication Critical patent/BR9914051A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

Patente de Invenção: <B>"MéTODOS PARA ADMINISTRAçãO DE ANTIBIóTICOS"<D>. A presente invenção refere-se a métodos para administrar uma quantidade eficaz terapeuticamente de daptomicina enquanto minimizando toxicidade do músculo esquelético. Os métodos fornecem administração de daptomicina em um intervalo de dosagem de 24 horas ou maior. Este intervalo de dosagem longo minimiza toxicidade do músculo esquelético e permite pico maior de concentração de daptomicina, o qual é relacionado a eficácia de daptomicina. A invenção também fornece métodos de administrar antibiótico de lipopeptídeos outros além de daptomicina enquanto minimizando toxicidade do músculo esquelético administrando uma quantidade eficaz terapeuticamente do antibiótico de lipopeptídeo em um intervalo de dosagem que não resulta em toxicidade muscular. A invenção também fornece métodos de administrar quinopristina/dalfopristina enquanto minimizando toxicidade do músculo esquelético administrando uma quantidade eficaz terapeuticamente de quinopristina/dalfopristina em um intervalo de dosagem que não resulta em toxicidade muscular.
BR9914051-9A 1998-09-25 1999-09-24 Métodos para administração de antibióticos BR9914051A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10182898P 1998-09-25 1998-09-25
US12575099P 1999-03-24 1999-03-24
PCT/US1999/022366 WO2000018419A2 (en) 1998-09-25 1999-09-24 Methods for administration of antibiotics

Publications (1)

Publication Number Publication Date
BR9914051A true BR9914051A (pt) 2001-06-19

Family

ID=26798675

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9914051-9A BR9914051A (pt) 1998-09-25 1999-09-24 Métodos para administração de antibióticos

Country Status (26)

Country Link
US (2) US6468967B1 (pt)
EP (2) EP1115417B1 (pt)
JP (4) JP4184607B2 (pt)
KR (2) KR20100051735A (pt)
CN (2) CN1150029C (pt)
AT (1) ATE322280T1 (pt)
AU (1) AU764348B2 (pt)
BR (1) BR9914051A (pt)
CA (1) CA2344318C (pt)
CY (3) CY1105556T1 (pt)
DE (3) DE122006000049I2 (pt)
DK (2) DK1115417T3 (pt)
ES (2) ES2603086T3 (pt)
HK (1) HK1040363B (pt)
HU (1) HU230656B1 (pt)
IS (2) IS5890A (pt)
LU (1) LU91254I2 (pt)
NL (1) NL300232I2 (pt)
NO (1) NO20011454L (pt)
NZ (1) NZ510690A (pt)
PL (2) PL206091B1 (pt)
PT (2) PT1674107T (pt)
RU (1) RU2363489C9 (pt)
SI (2) SI1115417T1 (pt)
TR (1) TR200100841T2 (pt)
WO (1) WO2000018419A2 (pt)

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PL206091B1 (pl) 1998-09-25 2010-06-30 Cubist Pharmaceuticals Zastosowania daptomycyny
EP2295444A3 (en) 1999-12-15 2011-03-23 Cubist Pharmaceutical Inc. Lipopeptides as antibacterial agents
US6696412B1 (en) 2000-01-20 2004-02-24 Cubist Pharmaceuticals, Inc. High purity lipopeptides, Lipopeptide micelles and processes for preparing same
KR20080036661A (ko) 2000-12-18 2008-04-28 큐비스트 파마슈티컬즈 인코포레이티드 정제된 리포펩티드의 제조 방법
US20060014674A1 (en) 2000-12-18 2006-01-19 Dennis Keith Methods for preparing purified lipopeptides
WO2002059145A1 (en) * 2000-12-18 2002-08-01 Cubist Pharmaceuticals, Inc. Methods for preparing purified lipopeptides
EP1932853A1 (en) 2001-08-06 2008-06-18 Cubist Pharmaceutical Inc. Novel depsipeptides and process for preparing same
AU2003274927A1 (en) * 2002-08-23 2004-03-11 Genome Therapeutics Corporation Methods and reagents for preventing bacteremias
US20060074014A1 (en) * 2002-11-18 2006-04-06 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
US20050277581A1 (en) * 2002-11-18 2005-12-15 Vicuron Pharmaceuticals Inc. Dalbavancin compositions for treatment of bacterial infections
US20050220862A1 (en) * 2004-03-31 2005-10-06 Bernstein Joel E Compositions with reduced hepatotoxicity
US20060004185A1 (en) * 2004-07-01 2006-01-05 Leese Richard A Peptide antibiotics and peptide intermediates for their prepartion
US20060014677A1 (en) * 2004-07-19 2006-01-19 Isotechnika International Inc. Method for maximizing efficacy and predicting and minimizing toxicity of calcineurin inhibitor compounds
US20080051326A1 (en) * 2004-11-12 2008-02-28 Alexander Dylan C Antiinfective Lipopeptides
US7838532B2 (en) * 2005-05-18 2010-11-23 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US8524734B2 (en) 2005-05-18 2013-09-03 Mpex Pharmaceuticals, Inc. Aerosolized fluoroquinolones and uses thereof
US20070238630A1 (en) * 2006-03-29 2007-10-11 Phillips Douglas H Subcutaneous skin cleanser
EP2018864A1 (en) * 2007-07-23 2009-01-28 Biomet Deutschland GmbH Pharmaceutical composition, substrate comprising a pharmaceutical composition, and use of a pharmaceutical composition
MX2010009628A (es) * 2008-03-04 2010-09-28 Elan Pharma Int Ltd Formulaciones liquidas estables de agentes antiinfecciosos, y regimenes de dosificacion ajustados de los agentes antiinfecciosos.
MX2011000696A (es) 2008-07-17 2011-07-29 Acorda Therapeutics Inc Dosificacion terapeutica de una neurregulina o una subsecuencia de la misma para el tratamiento o la profilaxis de insuficiencia cardiaca.
DE102008046610A1 (de) * 2008-09-09 2010-03-11 Biomet Deutschland Gmbh Verwendung einer pharmazeutischen Zusammensetzung zur lokalen Infektionstherapie sowie Medizinprodukt
JP2012505223A (ja) 2008-10-07 2012-03-01 エムペックス・ファーマシューティカルズ・インコーポレーテッド 薬物動態の改善のためのエアゾールフルオロキノロン配合物
ES2809177T3 (es) 2008-10-07 2021-03-03 Horizon Orphan Llc Inhalación de levofloxacino para reducir la inflamación pulmonar
WO2010048630A1 (en) * 2008-10-24 2010-04-29 Los Angeles Biomedical Reserch Institute At Harbor-Ucla Medical Center Anti-infective hydroxy-phenyl-benzoates and methods of use
EP2674437A1 (en) * 2008-12-22 2013-12-18 Cubist Pharmaceuticals, Inc. Novel antibacterial agents for the treatment of GRAM positive infections
AR074874A1 (es) 2008-12-23 2011-02-16 Biosource Pharm Inc Composiciones antibioticas para el tratamiento de infecciones gram negativas. metodo. uso. compuesto.
CA2767614C (en) * 2009-07-13 2019-01-15 Cempra Pharmaceuticals Inc. Fusidic acid dosing regimens for treatment of bacterial infections
US8450300B2 (en) * 2009-07-13 2013-05-28 Cempra Pharmaceuticals Inc. Fusidic acid dosing regimens for treatment of bacterial infections
CA2773033C (en) 2009-09-04 2016-10-11 Mpex Pharmaceuticals, Inc. Use of aerosolized levofloxacin for treating cystic fibrosis
FI2504353T4 (fi) 2009-11-23 2023-11-30 Cubist Pharmaceuticals Llc Lipopeptidikoostumukset ja vastaavat menetelmät
US8247394B2 (en) 2010-06-02 2012-08-21 Cempra Pharmaceuticals Inc. Methods of treating urethritis and related infections using fusidic acid
US8415307B1 (en) 2010-06-23 2013-04-09 Biosource Pharm, Inc. Antibiotic compositions for the treatment of gram negative infections
US8461188B2 (en) 2011-10-20 2013-06-11 Trius Therapeutics, Inc. Therapeutic combination of daptomycin and protein synthesis inhibitor antibiotic, and methods of use
US8933232B2 (en) 2012-03-30 2015-01-13 Cubist Pharmaceuticals, Inc. 1,3,4-oxadiazole and 1,3,4-thiadiazole beta-lactamase inhibitors
ES2552754T1 (es) * 2012-09-11 2015-12-02 Hospira Australia Pty Ltd Formulaciones de daptomicina y usos de la misma
CN103006562B (zh) * 2013-01-21 2014-09-17 西南大学 达托霉素醇质体制剂
TWI641372B (zh) 2013-03-15 2018-11-21 美商梅琳塔有限責任公司 使用抗生素治療超重和肥胖患者感染的方法
US10647746B2 (en) 2016-04-08 2020-05-12 Versitech Limited Antibacterial cyclic lipopeptides
US11667674B2 (en) 2016-04-08 2023-06-06 Versitech Limited Antibacterial cyclic lipopeptides
JP2019515007A (ja) * 2016-05-13 2019-06-06 スペロ ポテンシエーター インコーポレイテッドＳｐｅｒｏ Ｐｏｔｅｎｔｉａｔｏｒ， Ｉｎｃ． 新規カチオン性ペプチドｓｐｒ７４１による、抗生物質活性の増強
CN114788814B (zh) * 2021-01-26 2023-10-13 浙江创新生物有限公司 一种高稳定性的注射用达托霉素组合物及其制备方法和其应用

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Also Published As

Publication number Publication date
NO20011454L (no) 2001-05-25
NZ510690A (en) 2002-10-25
PT1115417E (pt) 2006-07-31
AU6268799A (en) 2000-04-17
CN1150029C (zh) 2004-05-19
EP1674107B1 (en) 2016-08-24
HK1040363A1 (en) 2002-06-07
JP2003321389A (ja) 2003-11-11
JP4184607B2 (ja) 2008-11-19
DE69930758T2 (de) 2007-04-26
AU764348B2 (en) 2003-08-14
NO20011454D0 (no) 2001-03-22
TR200100841T2 (tr) 2002-01-21
WO2000018419A2 (en) 2000-04-06
HUP0103874A3 (en) 2002-09-30
CY1118334T1 (el) 2017-06-28
DK1115417T3 (da) 2006-07-31
EP1674107A8 (en) 2006-10-04
DE122006000049I2 (de) 2007-11-08
CY2006003I2 (el) 2009-11-04
EP1115417B1 (en) 2006-04-05
CY1105556T1 (el) 2010-07-28
CN1530136A (zh) 2004-09-22
JP2006335773A (ja) 2006-12-14
RU2363489C2 (ru) 2009-08-10
ATE322280T1 (de) 2006-04-15
HU230656B1 (hu) 2017-06-28
KR20010075327A (ko) 2001-08-09
EP1674107B8 (en) 2017-01-25
PL206091B1 (pl) 2010-06-30
JP2004339238A (ja) 2004-12-02
CA2344318C (en) 2006-07-04
PL348328A1 (en) 2002-05-20
DE69930758D1 (de) 2006-05-18
DE122006000049I1 (de) 2007-01-04
CY2006003I1 (el) 2009-11-04
SI1674107T1 (sl) 2017-01-31
EP1674107A2 (en) 2006-06-28
KR20100051735A (ko) 2010-05-17
CA2344318A1 (en) 2000-04-06
NL300232I2 (nl) 2007-01-02
WO2000018419A3 (en) 2000-07-06
CN1348382A (zh) 2002-05-08
SI1115417T1 (sl) 2006-08-31
HUP0103874A2 (hu) 2002-02-28
JP2002525335A (ja) 2002-08-13
RU2363489C9 (ru) 2010-03-20
LU91254I2 (fr) 2006-08-28
US20020142948A1 (en) 2002-10-03
DK1674107T3 (en) 2016-12-19
US6468967B1 (en) 2002-10-22
PL203689B1 (pl) 2009-11-30
RU2004106569A (ru) 2005-08-10
ES2603086T3 (es) 2017-02-23
ES2259845T3 (es) 2006-10-16
EP1115417A2 (en) 2001-07-18
IS5890A (is) 2001-03-14
PT1674107T (pt) 2016-12-07
IS8807A (is) 2009-03-10
EP1674107A3 (en) 2012-06-20
US6852689B2 (en) 2005-02-08
HK1040363B (zh) 2007-01-26
NL300232I1 (nl) 2006-09-01

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Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B25G Requested change of headquarter approved

Owner name: CUBIST PHARMACEUTICALS, INC. (US)

Free format text: SEDE ALTERADA CONFORME SOLICITADO NA PETICAO NO 020100048642/RJ DE 31/05/2010.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 10 (VIII) E 11 DA LPI.

B12B Appeal against refusal [chapter 12.2 patent gazette]
B25E Requested change of name of applicant rejected

Owner name: CUBIST PHARMACEUTICALS, INC. (US)

B25H Request for change of headquarter rejected

Owner name: CUBIST PHARMACEUTICALS, INC. (US)