BR9911611A - Fenóis rádio-iodados para braquiterapia - Google Patents
Fenóis rádio-iodados para braquiterapiaInfo
- Publication number
- BR9911611A BR9911611A BR9911611-1A BR9911611A BR9911611A BR 9911611 A BR9911611 A BR 9911611A BR 9911611 A BR9911611 A BR 9911611A BR 9911611 A BR9911611 A BR 9911611A
- Authority
- BR
- Brazil
- Prior art keywords
- brachytherapy
- iodized
- phenols
- radio
- compounds
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
- A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Optics & Photonics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Patente de Invenção: <B>"FENóIS RáDIO-IODADOS PARA BRAQUITERAPIA"<D>. A presente invenção refere-se ao uso de um composto fenólico rádio-iodado da fórmula (II) em que: m e n são, independentemente, 0, 1, 2 ou 3, X é um grupo que é negativa ou positivamente carregado em pH fisiológico, R, R¹, R² e R³ são, independentemente, hidrogênio, C~ 1~-C~ 4~ alquila ou um grupo carboxila e I^ *^ é ^ 123^I, ^ 131^I ou ^ 125^I e seus sais farmaceuticamente aceitáveis. O composto é formulado e usado in vivo em um animal em braquiterapia em um catéter implantável. Além disso, devido à rápida eliminação renal desses compostos, eles podem ser usados para estudar a função renal. Um processo para preparar esses compostos também é divulgado.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8776998P | 1998-06-02 | 1998-06-02 | |
PCT/US1999/012161 WO1999062564A1 (en) | 1998-06-02 | 1999-06-01 | Radioiodinated phenols for brachytherapy |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9911611A true BR9911611A (pt) | 2001-02-06 |
Family
ID=22207139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9911611-1A BR9911611A (pt) | 1998-06-02 | 1999-06-01 | Fenóis rádio-iodados para braquiterapia |
Country Status (11)
Country | Link |
---|---|
US (4) | US6315979B1 (pt) |
EP (1) | EP1083937B1 (pt) |
JP (1) | JP2002516883A (pt) |
KR (1) | KR100589568B1 (pt) |
AT (1) | ATE259247T1 (pt) |
AU (1) | AU755019B2 (pt) |
BR (1) | BR9911611A (pt) |
CA (1) | CA2334146C (pt) |
DE (1) | DE69914748T2 (pt) |
IL (1) | IL140029A0 (pt) |
WO (1) | WO1999062564A1 (pt) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6572823B1 (en) * | 1998-12-09 | 2003-06-03 | Bristol-Myers Squibb Pharma Company | Apparatus and method for reconstituting a solution |
US6637056B1 (en) * | 2001-06-01 | 2003-10-28 | Analogic Corporation | Lifting apparatus and method for patient table |
US7238338B1 (en) * | 2001-06-22 | 2007-07-03 | Triumf | System and method for the large scale labeling of compounds with radiohalogens |
US7783006B2 (en) * | 2003-10-10 | 2010-08-24 | Xoft, Inc. | Radiation treatment using x-ray source |
US7894880B2 (en) * | 2003-10-23 | 2011-02-22 | The Board Of Trustees Of The Leland Stanford Junior University | Measurement of renal extraction fraction using contrast enhanced computed tomography |
US20060005844A1 (en) * | 2004-07-08 | 2006-01-12 | Coulter George G | Rolling tube apparatus and method for treating a wound |
GB0514087D0 (en) * | 2005-07-11 | 2005-08-17 | Ge Healthcare Ltd | Stabilised radiopharmaceutical compositions |
US20070207266A1 (en) * | 2006-02-15 | 2007-09-06 | Lemke Harald K | Method and apparatus for coating particulates utilizing physical vapor deposition |
FR2928028B1 (fr) * | 2008-02-27 | 2011-07-15 | St Microelectronics Crolles 2 | Procede de fabrication d'un dispositif semi-conducteur a grille enterree et circuit integre correspondant. |
KR101130737B1 (ko) * | 2008-12-24 | 2012-03-28 | 경북대학교 산학협력단 | 방사성 세포 표지자 |
US8663210B2 (en) | 2009-05-13 | 2014-03-04 | Novian Health, Inc. | Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy |
US10610807B2 (en) * | 2014-01-17 | 2020-04-07 | Repligen Corporation | Sterilizing chromatography columns |
US20220199274A1 (en) * | 2020-12-18 | 2022-06-23 | The Catholic University Of America | Methods for removing iodate from aqueous solutions |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE139918C (pt) * | ||||
DE2145282C3 (de) * | 1971-09-10 | 1975-06-05 | Hoechst Ag, 6000 Frankfurt | 1-(Jodhydroxyphenyl)-2-aminopropanderivate, Verfahren zu ihrer Herstellung und diagnostisches Mittel |
US3947448A (en) * | 1972-05-17 | 1976-03-30 | Laboratorios Del Dr. Esteve Sa | Salts of novel p-dihydroxybenezene disulfonic acids |
US4197288A (en) * | 1977-01-17 | 1980-04-08 | Burroughs Wellcome Co. | Neuroleptic radioreceptor assay method and kit |
US4279887A (en) * | 1978-11-29 | 1981-07-21 | Medi-Physics, Inc. | Amides useful as brain imaging agents |
US4574079A (en) * | 1983-05-27 | 1986-03-04 | Gavras Haralambos P | Radiolabeled angiotensin converting enzyme inhibitors for radiolabeling mammalian organ sites |
US5393512A (en) * | 1985-01-14 | 1995-02-28 | Vanderheyden; Jean-Luc | Stable therapeutic radionuclide compositions and methods for preparation thereof |
US5045303A (en) * | 1985-05-17 | 1991-09-03 | Neorx Corporation | Radiohalogenated small molecules for protein labeling |
US4994013A (en) | 1988-07-28 | 1991-02-19 | Best Industries, Inc. | Pellet for a radioactive seed |
US5429582A (en) | 1991-06-14 | 1995-07-04 | Williams; Jeffery A. | Tumor treatment |
US6027710A (en) * | 1996-09-18 | 2000-02-22 | Nihon Medi-Physiscs Co., Ltd. | Radiation-protecting agent |
US5961955A (en) | 1997-06-03 | 1999-10-05 | Coulter Pharmaceutical, Inc. | Radioprotectant for peptides labeled with radioisotope |
-
1999
- 1999-06-01 US US09/323,359 patent/US6315979B1/en not_active Expired - Lifetime
- 1999-06-01 DE DE69914748T patent/DE69914748T2/de not_active Expired - Fee Related
- 1999-06-01 AT AT99930136T patent/ATE259247T1/de not_active IP Right Cessation
- 1999-06-01 BR BR9911611-1A patent/BR9911611A/pt not_active Application Discontinuation
- 1999-06-01 AU AU46737/99A patent/AU755019B2/en not_active Ceased
- 1999-06-01 IL IL14002999A patent/IL140029A0/xx unknown
- 1999-06-01 KR KR1020007013660A patent/KR100589568B1/ko not_active IP Right Cessation
- 1999-06-01 WO PCT/US1999/012161 patent/WO1999062564A1/en active IP Right Grant
- 1999-06-01 JP JP2000551818A patent/JP2002516883A/ja active Pending
- 1999-06-01 EP EP99930136A patent/EP1083937B1/en not_active Expired - Lifetime
- 1999-06-01 CA CA002334146A patent/CA2334146C/en not_active Expired - Fee Related
-
2000
- 2000-09-28 US US09/671,982 patent/US6506363B1/en not_active Expired - Fee Related
- 2000-09-28 US US09/672,541 patent/US6506364B1/en not_active Expired - Fee Related
-
2001
- 2001-12-18 US US10/022,885 patent/US6861044B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US6506364B1 (en) | 2003-01-14 |
EP1083937A1 (en) | 2001-03-21 |
DE69914748D1 (de) | 2004-03-18 |
US6506363B1 (en) | 2003-01-14 |
US6861044B2 (en) | 2005-03-01 |
KR100589568B1 (ko) | 2006-06-14 |
US6315979B1 (en) | 2001-11-13 |
US20020081662A1 (en) | 2002-06-27 |
IL140029A0 (en) | 2002-02-10 |
AU755019B2 (en) | 2002-11-28 |
CA2334146A1 (en) | 1999-12-09 |
JP2002516883A (ja) | 2002-06-11 |
ATE259247T1 (de) | 2004-02-15 |
CA2334146C (en) | 2008-11-18 |
KR20010052519A (ko) | 2001-06-25 |
AU4673799A (en) | 1999-12-20 |
EP1083937B1 (en) | 2004-02-11 |
DE69914748T2 (de) | 2004-12-02 |
WO1999062564A1 (en) | 1999-12-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
B25A | Requested transfer of rights approved |
Free format text: DOW GLOBAL TECHNOLOGIES INC (US) |
|
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AO REQUISITO DE ATIVIDADE INVENTIVA ( ART. 8O C/C ART. 13 DA LPI ) E SE ENCONTRA EM DESACORDO COM O ARTIGO 25. |
|
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |