BR9911611A - Fenóis rádio-iodados para braquiterapia - Google Patents

Fenóis rádio-iodados para braquiterapia

Info

Publication number
BR9911611A
BR9911611A BR9911611-1A BR9911611A BR9911611A BR 9911611 A BR9911611 A BR 9911611A BR 9911611 A BR9911611 A BR 9911611A BR 9911611 A BR9911611 A BR 9911611A
Authority
BR
Brazil
Prior art keywords
brachytherapy
iodized
phenols
radio
compounds
Prior art date
Application number
BR9911611-1A
Other languages
English (en)
Inventor
Jaime Simon
Keith R Frank
Alan D Strickland
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Publication of BR9911611A publication Critical patent/BR9911611A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0406—Amines, polyamines, e.g. spermine, spermidine, amino acids, (bis)guanidines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Patente de Invenção: <B>"FENóIS RáDIO-IODADOS PARA BRAQUITERAPIA"<D>. A presente invenção refere-se ao uso de um composto fenólico rádio-iodado da fórmula (II) em que: m e n são, independentemente, 0, 1, 2 ou 3, X é um grupo que é negativa ou positivamente carregado em pH fisiológico, R, R¹, R² e R³ são, independentemente, hidrogênio, C~ 1~-C~ 4~ alquila ou um grupo carboxila e I^ *^ é ^ 123^I, ^ 131^I ou ^ 125^I e seus sais farmaceuticamente aceitáveis. O composto é formulado e usado in vivo em um animal em braquiterapia em um catéter implantável. Além disso, devido à rápida eliminação renal desses compostos, eles podem ser usados para estudar a função renal. Um processo para preparar esses compostos também é divulgado.
BR9911611-1A 1998-06-02 1999-06-01 Fenóis rádio-iodados para braquiterapia BR9911611A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8776998P 1998-06-02 1998-06-02
PCT/US1999/012161 WO1999062564A1 (en) 1998-06-02 1999-06-01 Radioiodinated phenols for brachytherapy

Publications (1)

Publication Number Publication Date
BR9911611A true BR9911611A (pt) 2001-02-06

Family

ID=22207139

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9911611-1A BR9911611A (pt) 1998-06-02 1999-06-01 Fenóis rádio-iodados para braquiterapia

Country Status (11)

Country Link
US (4) US6315979B1 (pt)
EP (1) EP1083937B1 (pt)
JP (1) JP2002516883A (pt)
KR (1) KR100589568B1 (pt)
AT (1) ATE259247T1 (pt)
AU (1) AU755019B2 (pt)
BR (1) BR9911611A (pt)
CA (1) CA2334146C (pt)
DE (1) DE69914748T2 (pt)
IL (1) IL140029A0 (pt)
WO (1) WO1999062564A1 (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6572823B1 (en) * 1998-12-09 2003-06-03 Bristol-Myers Squibb Pharma Company Apparatus and method for reconstituting a solution
US6637056B1 (en) * 2001-06-01 2003-10-28 Analogic Corporation Lifting apparatus and method for patient table
US7238338B1 (en) * 2001-06-22 2007-07-03 Triumf System and method for the large scale labeling of compounds with radiohalogens
US7783006B2 (en) * 2003-10-10 2010-08-24 Xoft, Inc. Radiation treatment using x-ray source
US7894880B2 (en) * 2003-10-23 2011-02-22 The Board Of Trustees Of The Leland Stanford Junior University Measurement of renal extraction fraction using contrast enhanced computed tomography
US20060005844A1 (en) * 2004-07-08 2006-01-12 Coulter George G Rolling tube apparatus and method for treating a wound
GB0514087D0 (en) * 2005-07-11 2005-08-17 Ge Healthcare Ltd Stabilised radiopharmaceutical compositions
US20070207266A1 (en) * 2006-02-15 2007-09-06 Lemke Harald K Method and apparatus for coating particulates utilizing physical vapor deposition
FR2928028B1 (fr) * 2008-02-27 2011-07-15 St Microelectronics Crolles 2 Procede de fabrication d'un dispositif semi-conducteur a grille enterree et circuit integre correspondant.
KR101130737B1 (ko) * 2008-12-24 2012-03-28 경북대학교 산학협력단 방사성 세포 표지자
US8663210B2 (en) 2009-05-13 2014-03-04 Novian Health, Inc. Methods and apparatus for performing interstitial laser therapy and interstitial brachytherapy
US10610807B2 (en) * 2014-01-17 2020-04-07 Repligen Corporation Sterilizing chromatography columns
US20220199274A1 (en) * 2020-12-18 2022-06-23 The Catholic University Of America Methods for removing iodate from aqueous solutions

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE139918C (pt) *
DE2145282C3 (de) * 1971-09-10 1975-06-05 Hoechst Ag, 6000 Frankfurt 1-(Jodhydroxyphenyl)-2-aminopropanderivate, Verfahren zu ihrer Herstellung und diagnostisches Mittel
US3947448A (en) * 1972-05-17 1976-03-30 Laboratorios Del Dr. Esteve Sa Salts of novel p-dihydroxybenezene disulfonic acids
US4197288A (en) * 1977-01-17 1980-04-08 Burroughs Wellcome Co. Neuroleptic radioreceptor assay method and kit
US4279887A (en) * 1978-11-29 1981-07-21 Medi-Physics, Inc. Amides useful as brain imaging agents
US4574079A (en) * 1983-05-27 1986-03-04 Gavras Haralambos P Radiolabeled angiotensin converting enzyme inhibitors for radiolabeling mammalian organ sites
US5393512A (en) * 1985-01-14 1995-02-28 Vanderheyden; Jean-Luc Stable therapeutic radionuclide compositions and methods for preparation thereof
US5045303A (en) * 1985-05-17 1991-09-03 Neorx Corporation Radiohalogenated small molecules for protein labeling
US4994013A (en) 1988-07-28 1991-02-19 Best Industries, Inc. Pellet for a radioactive seed
US5429582A (en) 1991-06-14 1995-07-04 Williams; Jeffery A. Tumor treatment
US6027710A (en) * 1996-09-18 2000-02-22 Nihon Medi-Physiscs Co., Ltd. Radiation-protecting agent
US5961955A (en) 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope

Also Published As

Publication number Publication date
US6506364B1 (en) 2003-01-14
EP1083937A1 (en) 2001-03-21
DE69914748D1 (de) 2004-03-18
US6506363B1 (en) 2003-01-14
US6861044B2 (en) 2005-03-01
KR100589568B1 (ko) 2006-06-14
US6315979B1 (en) 2001-11-13
US20020081662A1 (en) 2002-06-27
IL140029A0 (en) 2002-02-10
AU755019B2 (en) 2002-11-28
CA2334146A1 (en) 1999-12-09
JP2002516883A (ja) 2002-06-11
ATE259247T1 (de) 2004-02-15
CA2334146C (en) 2008-11-18
KR20010052519A (ko) 2001-06-25
AU4673799A (en) 1999-12-20
EP1083937B1 (en) 2004-02-11
DE69914748T2 (de) 2004-12-02
WO1999062564A1 (en) 1999-12-09

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Free format text: DOW GLOBAL TECHNOLOGIES INC (US)

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFERIMENTO DO PRESENTE PEDIDO, UMA VEZ QUE O MESMO NAO ATENDE AO REQUISITO DE ATIVIDADE INVENTIVA ( ART. 8O C/C ART. 13 DA LPI ) E SE ENCONTRA EM DESACORDO COM O ARTIGO 25.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.