HUP0300632A2 - Pangásos szívelégtelenség kezelése egy diuretikus hatóanyagot és egy vazopresszin antagonistát tartalmazó készítménnyel - Google Patents
Pangásos szívelégtelenség kezelése egy diuretikus hatóanyagot és egy vazopresszin antagonistát tartalmazó készítménnyelInfo
- Publication number
- HUP0300632A2 HUP0300632A2 HU0300632A HUP0300632A HUP0300632A2 HU P0300632 A2 HUP0300632 A2 HU P0300632A2 HU 0300632 A HU0300632 A HU 0300632A HU P0300632 A HUP0300632 A HU P0300632A HU P0300632 A2 HUP0300632 A2 HU P0300632A2
- Authority
- HU
- Hungary
- Prior art keywords
- group
- vasopressin antagonist
- treatment
- heart failure
- congestive heart
- Prior art date
Links
- 229940116211 Vasopressin antagonist Drugs 0.000 title abstract 3
- 239000003038 vasopressin antagonist Substances 0.000 title abstract 3
- 206010007559 Cardiac failure congestive Diseases 0.000 title abstract 2
- 206010019280 Heart failures Diseases 0.000 title abstract 2
- 239000002934 diuretic Substances 0.000 title abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical group [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000004103 aminoalkyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004663 dialkyl amino group Chemical group 0.000 abstract 1
- 230000001882 diuretic effect Effects 0.000 abstract 1
- 230000029142 excretion Effects 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 229940126601 medicinal product Drugs 0.000 abstract 1
- 229910001414 potassium ion Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- 229910001415 sodium ion Inorganic materials 0.000 abstract 1
- 210000002700 urine Anatomy 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
- A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Furan Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Pangásos szívelégtelenség kezelésére szolgáló gyógyszerkészítmény,mely egy diuretikum és egy vazopresszin-antagonista kombinációjáttartalmazza. Előnyösen alkalmazható vazopresszin-antagonistaként az(I) általános képletű vegyület vagy gyógyászati szempontbólalkalmazható sója, ahol az általános képletben R és R5 jelentésehidrogénatom vagy rövid szénláncú alkilcsoport; R1, R2 és R3 jelentéseegymástót függetlenül hidrogén-, halogénatom, rövid szénláncú alkil-,rövid szénláncú alkoxi-, amino-alkil- vagy dialkil-amino-csoport; R4jelentése hidrogénatom vagy fenil- vagy helyettesített fenilcsoport. Akészítmény növeli a vizeletben kiválasztott víz mennyiségét éscsökkenti a nátrium- és káliumionok kiválasztását. Ó
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20143100P | 2000-05-03 | 2000-05-03 | |
| PCT/US2001/009265 WO2001082920A2 (en) | 2000-05-03 | 2001-03-22 | Treatment of congestive heart failure with a composition comprising a diuretic agent and a vasopressin antagonist |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0300632A2 true HUP0300632A2 (hu) | 2003-08-28 |
| HUP0300632A3 HUP0300632A3 (en) | 2006-02-28 |
Family
ID=22745788
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0300632A HUP0300632A3 (en) | 2000-05-03 | 2001-03-22 | Treatment of congestive heart failure with a composition comprising a diuretic agent and a vasopressin antagonist |
Country Status (19)
| Country | Link |
|---|---|
| EP (1) | EP1280555B8 (hu) |
| JP (1) | JP2003535823A (hu) |
| KR (1) | KR20020093971A (hu) |
| CN (1) | CN1431915A (hu) |
| AT (1) | ATE326241T1 (hu) |
| AU (1) | AU2001249364A1 (hu) |
| BR (1) | BR0110566A (hu) |
| CA (1) | CA2407929C (hu) |
| CZ (1) | CZ20023587A3 (hu) |
| DE (1) | DE60119723T2 (hu) |
| ES (1) | ES2264444T3 (hu) |
| HU (1) | HUP0300632A3 (hu) |
| IL (1) | IL152590A0 (hu) |
| MX (1) | MXPA02010865A (hu) |
| NZ (1) | NZ522641A (hu) |
| PL (1) | PL358544A1 (hu) |
| SK (1) | SK15532002A3 (hu) |
| WO (1) | WO2001082920A2 (hu) |
| ZA (1) | ZA200209367B (hu) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040229781A1 (en) * | 2000-05-10 | 2004-11-18 | Marks Andrew Robert | Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias |
| WO2019141575A1 (de) * | 2018-01-16 | 2019-07-25 | Bayer Aktiengesellschaft | Unterstützung bei der behandlung von herzinsuffizienz |
| KR20220052561A (ko) | 2020-10-21 | 2022-04-28 | 장영진 | 어류 가공물 및/또는 콩 가공물을 유효성분으로 포함하는 심부전의 예방 또는 치료용 약학 조성물 |
-
2001
- 2001-03-22 AT AT01922578T patent/ATE326241T1/de not_active IP Right Cessation
- 2001-03-22 MX MXPA02010865A patent/MXPA02010865A/es active IP Right Grant
- 2001-03-22 NZ NZ522641A patent/NZ522641A/en unknown
- 2001-03-22 SK SK1553-2002A patent/SK15532002A3/sk not_active Application Discontinuation
- 2001-03-22 CA CA002407929A patent/CA2407929C/en not_active Expired - Fee Related
- 2001-03-22 EP EP01922578A patent/EP1280555B8/en not_active Expired - Lifetime
- 2001-03-22 AU AU2001249364A patent/AU2001249364A1/en not_active Abandoned
- 2001-03-22 PL PL01358544A patent/PL358544A1/xx not_active Application Discontinuation
- 2001-03-22 WO PCT/US2001/009265 patent/WO2001082920A2/en active IP Right Grant
- 2001-03-22 JP JP2001579795A patent/JP2003535823A/ja not_active Abandoned
- 2001-03-22 HU HU0300632A patent/HUP0300632A3/hu unknown
- 2001-03-22 BR BR0110566-3A patent/BR0110566A/pt not_active IP Right Cessation
- 2001-03-22 DE DE60119723T patent/DE60119723T2/de not_active Expired - Lifetime
- 2001-03-22 CZ CZ20023587A patent/CZ20023587A3/cs unknown
- 2001-03-22 CN CN01810483A patent/CN1431915A/zh active Pending
- 2001-03-22 ES ES01922578T patent/ES2264444T3/es not_active Expired - Lifetime
- 2001-03-22 KR KR1020027014636A patent/KR20020093971A/ko not_active Application Discontinuation
- 2001-03-22 IL IL15259001A patent/IL152590A0/xx unknown
-
2002
- 2002-11-18 ZA ZA200209367A patent/ZA200209367B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP1280555B8 (en) | 2006-06-28 |
| ES2264444T3 (es) | 2007-01-01 |
| CZ20023587A3 (cs) | 2003-06-18 |
| KR20020093971A (ko) | 2002-12-16 |
| MXPA02010865A (es) | 2003-03-27 |
| ATE326241T1 (de) | 2006-06-15 |
| JP2003535823A (ja) | 2003-12-02 |
| DE60119723D1 (de) | 2006-06-22 |
| WO2001082920A3 (en) | 2002-07-18 |
| EP1280555A2 (en) | 2003-02-05 |
| CA2407929C (en) | 2009-05-19 |
| HUP0300632A3 (en) | 2006-02-28 |
| CA2407929A1 (en) | 2001-11-08 |
| BR0110566A (pt) | 2003-04-01 |
| AU2001249364A1 (en) | 2001-11-12 |
| PL358544A1 (en) | 2004-08-09 |
| ZA200209367B (en) | 2004-02-18 |
| IL152590A0 (en) | 2003-05-29 |
| NZ522641A (en) | 2003-10-31 |
| SK15532002A3 (sk) | 2003-08-05 |
| DE60119723T2 (de) | 2007-04-26 |
| CN1431915A (zh) | 2003-07-23 |
| EP1280555B1 (en) | 2006-05-17 |
| WO2001082920A2 (en) | 2001-11-08 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NL350075I2 (hu) | ||
| GEP20094675B (en) | Heteroaryl- tetra-hydropiperidyl compounds useful for treating or preventing pain | |
| TW328086B (en) | Biphenylamides, compositions comprising them and the preparation and use thereof | |
| NO20074657L (no) | Nitrogenholdige aromatiske ringforbindelser | |
| CA2113229A1 (en) | Anti-fibrotic quinazolinone-containing compositions and methods for the use thereof | |
| MY121032A (en) | Heterocyclic compounds for inhibition of gastric acid secretion, processes for their preparation and pharmaceutical compositions thereof | |
| DK0794949T3 (da) | Hidtil ukendte 3,5-dioxo-(2H,4H)-1,2,4-triazinderivater, fremstilling heraf og deres anvendelse som lægemidler | |
| WO2003082798A8 (es) | Compuestos naturales y derivados de éstos para la prevención y el tratamiento de enfermedades cardiovasculares, hepáticas, renales y para aplicaciones cosméticas | |
| DE60045508D1 (de) | Dalda-analoge und ihre verwendung | |
| DE69514823D1 (de) | Polyanionische benzyl-glykosiden als inhibitoren zur glatten-muskelzellen-proliferation | |
| NO20022124L (no) | Imidazopyridinderivater som fosfodiesterase VII-inhibitorer | |
| HUP0401235A2 (hu) | 5-HT6 receptor affinitással rendelkező arilszulfonil-származékok, eljárás előállításukra és a vegyületeket tartalmazó gyógyászati készítmények | |
| ATE439128T1 (de) | Indol-3-carboxamide, deren herstellung und therapeutische verwendung | |
| PL344056A1 (en) | Piperididinyl and n-amidinopiperidinyl derivatives | |
| NO20022123L (no) | Osoksazolderivater for anvendelse som inhibitorer for fosfodiesterase VII | |
| DK1204658T3 (da) | Benzofurylpiperazin-serotoninagonister | |
| HUP0300632A2 (hu) | Pangásos szívelégtelenség kezelése egy diuretikus hatóanyagot és egy vazopresszin antagonistát tartalmazó készítménnyel | |
| MXPA04003278A (es) | Derivados de 5-metoxi-8-aril-?1,2,4?triazolo?1,5-a?piridina como antagonistas del receptor de adenosina. | |
| IL161843A (en) | Derivatives of 2-amino-4-pyridylmethyl-thiazoline for the preparation of medicaments for use as inhibitors of inducible no-synthase | |
| DE60020130D1 (de) | Verfahren zur herstellung 3-amino-gallensaurer derivate | |
| PT982305E (pt) | Novos derivados do indano-1-ol proceso para a sua preparacao e as composicoes farmaceuticas que os contem | |
| BR0112338A (pt) | Composto, composição farmacêutica, e, uso de um composto | |
| ATE250597T1 (de) | N-benzolsulfonyl-l-prolin derivate, verfahren zu ihrer herstellung und ihre therapeutische verwendung | |
| MX9802126A (es) | Compuestos heterociclicos novedosos. | |
| RU2000131615A (ru) | Применение производных арил(или гетероарил)азолилкарбинолов в производстве препарата для лечения нейрогенного воспаления |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |