BR9910671A - 24-hidroxivitamina d, análogos e utilizações dos mesmos - Google Patents
24-hidroxivitamina d, análogos e utilizações dos mesmosInfo
- Publication number
- BR9910671A BR9910671A BR9910671-0A BR9910671A BR9910671A BR 9910671 A BR9910671 A BR 9910671A BR 9910671 A BR9910671 A BR 9910671A BR 9910671 A BR9910671 A BR 9910671A
- Authority
- BR
- Brazil
- Prior art keywords
- hydroxyvitamin
- analogues
- treatment
- hydroxivitamine
- impoverishment
- Prior art date
Links
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- 238000011282 treatment Methods 0.000 abstract 2
- 201000002980 Hyperparathyroidism Diseases 0.000 abstract 1
- 210000000988 bone and bone Anatomy 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000003463 hyperproliferative effect Effects 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000028709 inflammatory response Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
- A61K31/592—9,10-Secoergostane derivatives, e.g. ergocalciferol, i.e. vitamin D2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
- A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A61P5/20—Drugs for disorders of the endocrine system of the parathyroid hormones for decreasing, blocking or antagonising the activity of PTH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
Abstract
"24-HIDROXIVITAMINA D, ANáLOGOS E UTILIZAçõES DOS MESMOS" A invenção provê compostos 24-hidroxivitamina D e sua utilização no tratamento e profilaxia de hiperparatiroidismo e doenças hiperproliferativas e na modulação das respostas imune e inflamatória, bem como o tratamento de distúrbios de depauperação óssea.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/086,969 US6242434B1 (en) | 1997-08-08 | 1998-05-29 | 24-hydroxyvitamin D, analogs and uses thereof |
PCT/US1999/012084 WO1999061398A2 (en) | 1998-05-29 | 1999-05-28 | 24-hydroxyvitamin d, analogs and uses thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9910671A true BR9910671A (pt) | 2001-06-19 |
Family
ID=22202045
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9910671-0A BR9910671A (pt) | 1998-05-29 | 1999-05-28 | 24-hidroxivitamina d, análogos e utilizações dos mesmos |
Country Status (13)
Country | Link |
---|---|
US (3) | US6242434B1 (pt) |
EP (1) | EP1080055B1 (pt) |
JP (1) | JP2002516299A (pt) |
CN (1) | CN1379675A (pt) |
AT (1) | ATE250566T1 (pt) |
AU (1) | AU757740B2 (pt) |
BR (1) | BR9910671A (pt) |
CA (1) | CA2332146A1 (pt) |
DE (1) | DE69911596T2 (pt) |
ES (1) | ES2209518T3 (pt) |
IL (1) | IL139355A (pt) |
NZ (1) | NZ507855A (pt) |
WO (1) | WO1999061398A2 (pt) |
Families Citing this family (36)
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US6242434B1 (en) * | 1997-08-08 | 2001-06-05 | Bone Care International, Inc. | 24-hydroxyvitamin D, analogs and uses thereof |
US20020183288A1 (en) * | 1995-04-03 | 2002-12-05 | Bone Care International, Inc. | Method for treating and preventing hyperparathyroidism |
US20040043971A1 (en) * | 1995-04-03 | 2004-03-04 | Bone Care International, Inc. | Method of treating and preventing hyperparathyroidism with active vitamin D analogs |
US20020128240A1 (en) * | 1996-12-30 | 2002-09-12 | Bone Care International, Inc. | Treatment of hyperproliferative diseases using active vitamin D analogues |
US6087350A (en) * | 1997-08-29 | 2000-07-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of pretreatment chemicals to enhance efficacy of cytotoxic agents |
US6359012B1 (en) * | 1999-12-22 | 2002-03-19 | Bone Care International, Inc. | Method for making 24(S)-hydroxyvitamin D2 |
WO2002006218A2 (en) * | 2000-07-18 | 2002-01-24 | Bone Care International, Inc. | STABILIZED 1α-HYDROXY VITAMIN D |
KR20040012983A (ko) * | 2001-07-03 | 2004-02-11 | 추가이 세이야쿠 가부시키가이샤 | 2차성 부갑상선 기능 항진증의 치료용 의약 조성물 및2차성 부갑상선 기능 항진증 치료에 수반되는 심혈관계합병증의 치료약 |
EA008072B1 (ru) * | 2001-12-03 | 2007-02-27 | Новацея, Инк. | Фармацевтические составы, содержащие соединения активного витамина d |
TWI329105B (en) | 2002-02-01 | 2010-08-21 | Rigel Pharmaceuticals Inc | 2,4-pyrimidinediamine compounds and their uses |
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CN102358738A (zh) * | 2003-07-30 | 2012-02-22 | 里格尔药品股份有限公司 | 2,4-嘧啶二胺化合物及其预防和治疗自体免疫疾病的用途 |
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US7094775B2 (en) * | 2004-06-30 | 2006-08-22 | Bone Care International, Llc | Method of treating breast cancer using a combination of vitamin D analogues and other agents |
ES2534603T3 (es) * | 2004-06-30 | 2015-04-24 | E-L Management Corp. | Composiciones cosméticas y procedimientos que comprenden Rhodiola Rosea |
US20060003950A1 (en) * | 2004-06-30 | 2006-01-05 | Bone Care International, Inc. | Method of treating prostatic diseases using a combination of vitamin D analogues and other agents |
US7914810B2 (en) * | 2005-05-06 | 2011-03-29 | Synthes Usa, Llc | Methods for the in situ treatment of bone cancer |
CA2607901C (en) | 2005-06-13 | 2016-08-16 | Rigel Pharmaceuticals, Inc. | Methods and compositions for treating degenerative bone disorders using a syk inhibitory 2,4-pyrimidinediamine |
PT1734251E (pt) * | 2005-06-17 | 2007-03-30 | Magneti Marelli Powertrain Spa | Injector de combustível |
PL1993559T3 (pl) | 2006-02-03 | 2017-01-31 | Opko Renal, Llc | Leczenie niedoboru i deficytu witaminy d z zastosowaniem 25-hydroksywitaminy d2 i 25-hydroksywitaminy d3 |
LT2679228T (lt) | 2006-06-21 | 2018-05-10 | Opko Ireland Global Holdings, Ltd. | Terapija naudojant vitamino d atstatymo agentą ir vitamino d hormoninį pakaitinį agentą |
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JP2010525080A (ja) | 2007-04-25 | 2010-07-22 | プロヴェンティヴ セラピュティックス リミテッド ライアビリティ カンパニー | 慢性腎臓病における続発性副甲状腺機能亢進症の安全かつ効果的な治療および予防方法 |
KR101495578B1 (ko) | 2007-04-25 | 2015-02-25 | 사이토크로마 인코포레이티드 | 비타민 d 부족 및 결핍의 치료 방법 |
US20090233889A1 (en) * | 2008-03-12 | 2009-09-17 | Uttam Saha | Stabilized 1,25-dihydroxyvitamin d2 and method of making same |
ES2954932T3 (es) | 2008-04-02 | 2023-11-27 | Eirgen Pharma Ltd | Métodos, composiciones, usos y kits útiles para la deficiencia de vitamina D y trastornos relacionados |
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US8470304B2 (en) * | 2009-08-04 | 2013-06-25 | Avidas Pharmaceuticals Llc | Therapeutic vitamin D sun-protecting formulations and methods for their use |
KR102125424B1 (ko) | 2010-03-29 | 2020-06-22 | 사이토크로마 인코포레이티드 | 부갑상선 수준을 낮추기 위한 방법 및 조성물 |
US9416102B2 (en) * | 2013-01-23 | 2016-08-16 | Wisconsin Alumni Research Foundation | (22E)-2-methylene-22-dehydro-1α,24,25-trihydroxy-19-nor-vitamin D3 analogs |
KR101847947B1 (ko) | 2013-03-15 | 2018-05-28 | 옵코 아이피 홀딩스 Ⅱ 인코포레이티드 | 안정화되고 변형된 비타민 d 방출 제형 |
CR20170085A (es) | 2014-08-07 | 2017-04-25 | Opko Ireland Global Holdings Ltd | Terapia adjuntiva con 25-hidroxi vitamina d |
TWI667366B (zh) * | 2014-09-19 | 2019-08-01 | 日商凸版印刷股份有限公司 | Film forming device and film forming method |
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-
1998
- 1998-05-29 US US09/086,969 patent/US6242434B1/en not_active Expired - Lifetime
-
1999
- 1999-05-28 IL IL13935599A patent/IL139355A/xx not_active IP Right Cessation
- 1999-05-28 AT AT99953332T patent/ATE250566T1/de not_active IP Right Cessation
- 1999-05-28 ES ES99953332T patent/ES2209518T3/es not_active Expired - Lifetime
- 1999-05-28 AU AU43243/99A patent/AU757740B2/en not_active Ceased
- 1999-05-28 JP JP2000550810A patent/JP2002516299A/ja active Pending
- 1999-05-28 EP EP99953332A patent/EP1080055B1/en not_active Expired - Lifetime
- 1999-05-28 NZ NZ507855A patent/NZ507855A/en unknown
- 1999-05-28 CN CN99806763A patent/CN1379675A/zh active Pending
- 1999-05-28 WO PCT/US1999/012084 patent/WO1999061398A2/en active IP Right Grant
- 1999-05-28 DE DE69911596T patent/DE69911596T2/de not_active Expired - Lifetime
- 1999-05-28 BR BR9910671-0A patent/BR9910671A/pt not_active Application Discontinuation
- 1999-05-28 CA CA002332146A patent/CA2332146A1/en not_active Abandoned
-
2001
- 2001-01-03 US US09/753,697 patent/US7122530B2/en not_active Expired - Fee Related
-
2006
- 2006-06-02 US US11/421,968 patent/US20060211661A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US7122530B2 (en) | 2006-10-17 |
AU757740B2 (en) | 2003-03-06 |
DE69911596D1 (de) | 2003-10-30 |
US6242434B1 (en) | 2001-06-05 |
WO1999061398A2 (en) | 1999-12-02 |
ATE250566T1 (de) | 2003-10-15 |
CN1379675A (zh) | 2002-11-13 |
IL139355A0 (en) | 2001-11-25 |
NZ507855A (en) | 2003-11-28 |
IL139355A (en) | 2005-08-31 |
EP1080055B1 (en) | 2003-09-24 |
ES2209518T3 (es) | 2004-06-16 |
AU4324399A (en) | 1999-12-13 |
EP1080055A2 (en) | 2001-03-07 |
US20010002397A1 (en) | 2001-05-31 |
JP2002516299A (ja) | 2002-06-04 |
DE69911596T2 (de) | 2004-07-01 |
US20060211661A1 (en) | 2006-09-21 |
CA2332146A1 (en) | 1999-12-02 |
WO1999061398A3 (en) | 2000-11-23 |
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