ES2055019T3 - Metodo para la conversion fotoquimica de compuestos de taquisterol en compuestos de previtamina d y de compuestos de trans-vitamina d en compuestos de cis-vitamina d. - Google Patents

Metodo para la conversion fotoquimica de compuestos de taquisterol en compuestos de previtamina d y de compuestos de trans-vitamina d en compuestos de cis-vitamina d.

Info

Publication number
ES2055019T3
ES2055019T3 ES89202959T ES89202959T ES2055019T3 ES 2055019 T3 ES2055019 T3 ES 2055019T3 ES 89202959 T ES89202959 T ES 89202959T ES 89202959 T ES89202959 T ES 89202959T ES 2055019 T3 ES2055019 T3 ES 2055019T3
Authority
ES
Spain
Prior art keywords
compounds
vitamin
compound
cis
trans
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89202959T
Other languages
English (en)
Inventor
Eric J Goethals
Sebastianus J Halkes
Robert B Koolstra
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Duphar International Research BV
Original Assignee
Duphar International Research BV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar International Research BV filed Critical Duphar International Research BV
Application granted granted Critical
Publication of ES2055019T3 publication Critical patent/ES2055019T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/333—Polymers modified by chemical after-treatment with organic compounds containing nitrogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C401/00—Irradiation products of cholesterol or its derivatives; Vitamin D derivatives, 9,10-seco cyclopenta[a]phenanthrene or analogues obtained by chemical preparation without irradiation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
    • C08F8/00—Chemical modification by after-treatment
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
    • C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
    • C08G65/32—Polymers modified by chemical after-treatment
    • C08G65/329—Polymers modified by chemical after-treatment with organic compounds
    • C08G65/337—Polymers modified by chemical after-treatment with organic compounds containing other elements

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Polyethers (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)

Abstract

DICHAS CONVERSIONES SE REALIZAN BAJO LA INFLUENCIA DE RADIACION POR EXPOSICION DEL COMPUESTO DE TAQUISTEROL Y EL DE TRANS-VITAMINA, RESPECTIVAMENTE DISUELTOS EN UN DISOLVENTE APROPIADO EN PRESENCIA DE UN FOTOSINTETIZADOR POLIMERICO QUE CONSISTE EN UNA CADENA DE POLIMERO (EJE. CENTRAL) QUE COMPRENDE UN ENLACE COVALENTEMENTE SINTETIZADO APROPIADO PARA LA CONVERSION FOTOQUIMICA, PARA ILUMINAR CON UNA LONGITUD DE ONDA DE APROX. 300 A 1.000NM, Y PARA SU AISLAMIENTO DEL COMPUESTO DE PREVITAMINA D Y DE CIS-VITAMINA D RESPECTIVAMENTE PARA LOS CUALES UN FOTOSINTETIZADOR ES USADO EN LA CADENA DE POLIMERO, LA CUAL HA SIDO SELECCIONADA DEL GRUPO QUE CONSISTE EN UNA CADENA POLIETER, UNA CADENA DE POLIMERO QUE CONTIENE GRUPOS AMINO Y UNA CADENA DE BLOQUES DE COPOLIMERO QUE COMPRENDE SEGMENTOS DE POLIETER Y/O SEGMENTOS DE POLIMERO QUE CONTIENEN GRUPOS AMINAS, DE MANERA QUE EL FOTOSINTETIZADOR POLIMERICO DISUELVE EN EL SISTEMA DISOLVENTE DURANTE LA EXPOSICION A LA RADIACION PERO CUALQUIERA SE PRECIPITAEN FRIO DESDE LA SOLUCION Y PUEDE SER SEPARADO, O EN CASO DE QUE DICHA CADENA DE POLIMERO COMPRENDA GRUPOS AMINAS PUEDE SER PROTONADOS CON UNA SUSTANCIA ACIDA APROPIADA Y ELIMINADOS EN UN TRATAMIENTO POSTERIOR. LA INVENCION TAMBIEN TRATA UN FOTOSINTETIZADOR PARA SER USADO EN DICHO METODO.
ES89202959T 1988-12-12 1989-11-22 Metodo para la conversion fotoquimica de compuestos de taquisterol en compuestos de previtamina d y de compuestos de trans-vitamina d en compuestos de cis-vitamina d. Expired - Lifetime ES2055019T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8803040 1988-12-12

Publications (1)

Publication Number Publication Date
ES2055019T3 true ES2055019T3 (es) 1994-08-16

Family

ID=19853363

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89202959T Expired - Lifetime ES2055019T3 (es) 1988-12-12 1989-11-22 Metodo para la conversion fotoquimica de compuestos de taquisterol en compuestos de previtamina d y de compuestos de trans-vitamina d en compuestos de cis-vitamina d.

Country Status (11)

Country Link
US (1) US5035783A (es)
EP (1) EP0373687B1 (es)
JP (1) JPH02202870A (es)
AT (1) ATE90075T1 (es)
AU (1) AU622958B2 (es)
CA (1) CA2004816A1 (es)
DE (1) DE68906866T2 (es)
DK (1) DK615789A (es)
ES (1) ES2055019T3 (es)
IL (1) IL92635A0 (es)
ZA (1) ZA899375B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0454204T3 (da) * 1990-04-27 1995-08-28 Duphar Int Res Fremgangsmåde til fotokemisk isomerisering af organiske forbindelser og indflydelse herpå af en fotosensibilisator
US5543016A (en) * 1991-07-12 1996-08-06 Inrad Photoconversion of steroids in microreactors
US20020183288A1 (en) * 1995-04-03 2002-12-05 Bone Care International, Inc. Method for treating and preventing hyperparathyroidism
US6242434B1 (en) * 1997-08-08 2001-06-05 Bone Care International, Inc. 24-hydroxyvitamin D, analogs and uses thereof
US20040043971A1 (en) * 1995-04-03 2004-03-04 Bone Care International, Inc. Method of treating and preventing hyperparathyroidism with active vitamin D analogs
US5972917A (en) * 1998-05-29 1999-10-26 Bone Care Int Inc 1 α-hydroxy-25-ene-vitamin D, analogs and uses thereof
JP2002516306A (ja) 1998-05-29 2002-06-04 ボーン ケア インターナショナル インコーポレイテッド ヒドロキシ−２５−エン−ビタミンｄ化合物の製造方法
AU2942100A (en) * 1999-03-11 2000-09-28 Kuraray Co., Ltd. Vitamin d derivatives and process for the preparation thereof
EP1458678A1 (en) * 2002-11-18 2004-09-22 Teva Pharmaceutical Industries Limited A crystallization method for purification of calcipotriene
US7094775B2 (en) 2004-06-30 2006-08-22 Bone Care International, Llc Method of treating breast cancer using a combination of vitamin D analogues and other agents
US20190116791A1 (en) * 2016-03-15 2019-04-25 Fmc Corporation Use of safeners with ppo inhibitor herbicides

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4609444A (en) * 1982-11-16 1986-09-02 Solarchem Corporation Photochemical reactions for commercial synthesis
US4517125A (en) * 1983-02-03 1985-05-14 Chugai Seiyaku Kabushiki Kaisha Novel vitamin D3 derivatives and process for producing the same
US4551214A (en) * 1983-07-01 1985-11-05 Hoffmann-La Roche Inc. Photochemical preparation of previtamin D
US4686023A (en) * 1985-11-26 1987-08-11 Solarchem Research, Division Of Brolor Investments, Ltd. Sensitized photochemical preparation of vitamin D
NO872850L (no) * 1986-07-09 1988-01-11 Solarchem Res Fotokjemisk sensitiverende materialer.
US4849076A (en) * 1987-10-13 1989-07-18 Neckers Douglas C Continuous oxidation method

Also Published As

Publication number Publication date
AU622958B2 (en) 1992-04-30
IL92635A0 (en) 1990-08-31
DE68906866T2 (de) 1993-09-09
AU4615589A (en) 1990-06-14
CA2004816A1 (en) 1990-06-12
ATE90075T1 (de) 1993-06-15
EP0373687A1 (en) 1990-06-20
DK615789A (da) 1990-06-13
ZA899375B (en) 1990-08-29
DK615789D0 (da) 1989-12-07
JPH02202870A (ja) 1990-08-10
EP0373687B1 (en) 1993-06-02
US5035783A (en) 1991-07-30
DE68906866D1 (de) 1993-07-08

Similar Documents

Publication Publication Date Title
EP0287817B1 (de) Photopolymerisierbares Gemisch und daraus hergestelltes Aufzeichnungsmaterial
ES2055019T3 (es) Metodo para la conversion fotoquimica de compuestos de taquisterol en compuestos de previtamina d y de compuestos de trans-vitamina d en compuestos de cis-vitamina d.
DE3686057D1 (de) Verfahren zur herstellung von polymerteilchen, diese polymerteilchen und ihre verwendung.
BR8306748A (pt) Mistura sensivel a luz,material para copias sensivel a luz preparado da mesma e processo para a preparacao de um molde de impressao a partir do material para copias
EP0284938A2 (de) Photopolymerisierbares Gemisch und daraus hergestelltes Aufzeichnungsmaterial
ATE53592T1 (de) Wasserloesliche, durch ionische gruppen substituierte cyclodextrin-polymere und verfahren zu deren herstellung.
JPS6433546A (en) Photoresist composition and photoresist device
DE68905549D1 (de) Ionenaustauschcherharzperlen und verfahren zu deren herstellung.
EP0321828A2 (de) Photopolymerisierbares Gemisch und daraus hergestelltes Aufzeichnungsmaterial
GB1313562A (en) Method for fixation of information or production of an image
EP0305115A2 (en) Improvements in or relating to radiation sensitive compounds
DE59301908D1 (de) Sulfoniumsalze und verfahren zu deren herstellung
DK453679A (da) Fotopolymeriserbare naterialer afledte belaegninger og andre polymeriserede produkter
DE3781696T2 (de) Barbitursaeure-verbindungen, diese enthaltende photoresists und verfahren zu deren herstellung.
EP0321826B1 (de) Photopolymerisierbares Gemisch und daraus hergestelltes Aufzeichnungsmaterial
EP0321827B1 (de) Photopolymerisierbares Gemisch und daraus hergestelltes Aufzeichnungsmaterial
JPH0612453B2 (ja) 光硬化性樹脂組成物
ATE87942T1 (de) Polymer mit betainstruktur, loesungsdiffusionsmembran, verfahren zu ihrer herstellung und ihre verwendung.
DE59004355D1 (de) Verfahren zur herstellung von reflektoren, insbesondere für kraftfahrzeugscheinwerfer.
PT84606B (pt) Processo para a preparacao de tetrasulfuretos de bis-(2,4-diamino-s-triazino-6-ilo) n,n'-substituidos e dos seus produtos de cisao molecular, e de composicoes de borracha vulcanizaveis contendo aqueles compostos
Castell et al. A general procedure for isotopic (deuterium) labelling of non‐steroidal antiinflammatory 2‐arylpropionic acids
DE69513590T2 (de) Verfahren zur Strukturierung von Poly(arylenvinylen)-Polymerfilmen durch Lichtbestrahlung
HORITO et al. Photochemistry and acid sensitivity of pyrimidine polymers
JPH07168356A (ja) 含窒素高分子化合物の固定化方法
ES474174A1 (es) Un procedimiento para la preparacion de polimeros reticula- bles por accion de la luz, con grupos de azidoftalimidilo enposicion lateral

Legal Events

Date Code Title Description
FC2A Grant refused

Effective date: 19920729

FG2A Definitive protection

Ref document number: 373687

Country of ref document: ES