BR9907283A - Vìrus do herpes simples, uso de um vìrus do herpes simples, composição farmacêutica, e, processos para estudar a função de gene heterólogo em uma célula de mamìfero e para produzir um vìrus do herpes simples - Google Patents

Vìrus do herpes simples, uso de um vìrus do herpes simples, composição farmacêutica, e, processos para estudar a função de gene heterólogo em uma célula de mamìfero e para produzir um vìrus do herpes simples

Info

Publication number
BR9907283A
BR9907283A BR9907283-1A BR9907283A BR9907283A BR 9907283 A BR9907283 A BR 9907283A BR 9907283 A BR9907283 A BR 9907283A BR 9907283 A BR9907283 A BR 9907283A
Authority
BR
Brazil
Prior art keywords
herpes simplex
simplex virus
gene
study
processes
Prior art date
Application number
BR9907283-1A
Other languages
English (en)
Inventor
Robert Stuart Coffin
David Seymour Latchman
Nicholas James Finnie
Original Assignee
Biovex Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biovex Ltd filed Critical Biovex Ltd
Publication of BR9907283A publication Critical patent/BR9907283A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/245—Herpetoviridae, e.g. herpes simplex virus
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16611—Simplexvirus, e.g. human herpesvirus 1, 2
    • C12N2710/16622—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

"VìRUS DO HERPES SIMPLES, USO DE UM VìRUS DO HERPES SIMPLES, COMPOSIçãO FARMACêUTICA, E, PROCESSOS PARA ESTUDAR A FUNçãO DE UM GENE HETERóLOGO EM UMA CéLULA DE MAMìFERO E PARA PRODUZIR UM VìRUS DO HERPES SIMPLES". A presente invenção proporciona uma cepa de vírus do herpes simples possuindo um gene ICP27 funcional e faltante de pelo menos um gene ICP4 funcional e um gene ICP34.5 funcional. Também proporciona o uso de uma cepa de vírus do herpes simples que é faltante de pelo menos um gene ICP4 funcional e um gene ICP34.5 funcional no tratamento de distúrbios do, ou de lesões no, sistema nervoso de um mamífero.
BR9907283-1A 1998-01-29 1999-01-29 Vìrus do herpes simples, uso de um vìrus do herpes simples, composição farmacêutica, e, processos para estudar a função de gene heterólogo em uma célula de mamìfero e para produzir um vìrus do herpes simples BR9907283A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9801930.0A GB9801930D0 (en) 1998-01-29 1998-01-29 Mutant herpes simplex viruses and uses thereof
PCT/GB1999/000306 WO1999038955A2 (en) 1998-01-29 1999-01-29 Mutant herpes simplex viruses and uses thereof

Publications (1)

Publication Number Publication Date
BR9907283A true BR9907283A (pt) 2000-10-24

Family

ID=10826120

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9907283-1A BR9907283A (pt) 1998-01-29 1999-01-29 Vìrus do herpes simples, uso de um vìrus do herpes simples, composição farmacêutica, e, processos para estudar a função de gene heterólogo em uma célula de mamìfero e para produzir um vìrus do herpes simples

Country Status (12)

Country Link
US (1) US6719982B1 (pt)
EP (1) EP1049769A2 (pt)
JP (1) JP2002501742A (pt)
KR (1) KR20010040430A (pt)
CN (1) CN1295612A (pt)
AU (1) AU749017B2 (pt)
BR (1) BR9907283A (pt)
CA (1) CA2319669A1 (pt)
GB (2) GB9801930D0 (pt)
HK (1) HK1035378A1 (pt)
IL (1) IL137531A0 (pt)
WO (1) WO1999038955A2 (pt)

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GB0408103D0 (en) * 2004-04-08 2004-05-12 Crusade Lab Ltd Novel herpes simplex viruses
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WO2007016239A2 (en) * 2005-07-29 2007-02-08 President And Fellows Of Harvard College Herpes simplex virus mutant and uses therefore
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KR20230051602A (ko) 2016-04-15 2023-04-18 알파인 이뮨 사이언시즈, 인코포레이티드 Icos 리간드 변이체 면역조절 단백질 및 그의 용도
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US11471488B2 (en) 2016-07-28 2022-10-18 Alpine Immune Sciences, Inc. CD155 variant immunomodulatory proteins and uses thereof
CN106318915B (zh) * 2016-09-21 2020-02-18 重庆宇珩生物科技有限公司 重组单纯疱疹病毒HSV-hTERTp_ICP4_LungCA-GFP及诊断试剂盒
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CN110546265A (zh) 2017-02-09 2019-12-06 因达普塔治疗公司 工程化自然杀伤(nk)细胞及其组合物和方法
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GB9801930D0 (en) 1998-01-29 1998-03-25 Univ London Mutant herpes simplex viruses and uses thereof

Also Published As

Publication number Publication date
GB9801930D0 (en) 1998-03-25
US6719982B1 (en) 2004-04-13
EP1049769A2 (en) 2000-11-08
JP2002501742A (ja) 2002-01-22
GB0020940D0 (en) 2000-10-11
HK1035378A1 (en) 2001-11-23
CN1295612A (zh) 2001-05-16
CA2319669A1 (en) 1999-08-05
GB2353529A (en) 2001-02-28
WO1999038955A3 (en) 1999-09-23
GB2353529B (en) 2003-01-15
AU2291199A (en) 1999-08-16
IL137531A0 (en) 2001-07-24
AU749017B2 (en) 2002-06-13
WO1999038955A2 (en) 1999-08-05
KR20010040430A (ko) 2001-05-15

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