BR9904355A - Processo para a preparação de dialquil fenil malonatos - Google Patents
Processo para a preparação de dialquil fenil malonatosInfo
- Publication number
- BR9904355A BR9904355A BR9904355-6A BR9904355A BR9904355A BR 9904355 A BR9904355 A BR 9904355A BR 9904355 A BR9904355 A BR 9904355A BR 9904355 A BR9904355 A BR 9904355A
- Authority
- BR
- Brazil
- Prior art keywords
- preparation
- dialkyl
- formula
- malonates
- dialkyl phenyl
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 3
- FQCRIFDLUQGBHF-UHFFFAOYSA-N 3-oxo-3-phenoxypropanoic acid Chemical class OC(=O)CC(=O)OC1=CC=CC=C1 FQCRIFDLUQGBHF-UHFFFAOYSA-N 0.000 title abstract 2
- QARVLSVVCXYDNA-UHFFFAOYSA-N bromobenzene Chemical compound BrC1=CC=CC=C1 QARVLSVVCXYDNA-UHFFFAOYSA-N 0.000 abstract 4
- OFOBLEOULBTSOW-UHFFFAOYSA-L Malonate Chemical compound [O-]C(=O)CC([O-])=O OFOBLEOULBTSOW-UHFFFAOYSA-L 0.000 abstract 2
- 150000001879 copper Chemical class 0.000 abstract 1
- 239000012442 inert solvent Substances 0.000 abstract 1
- 150000002690 malonic acid derivatives Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/30—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group
- C07C67/333—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
- C07C67/343—Preparation of carboxylic acid esters by modifying the acid moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton by increase in the number of carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/34—Esters of acyclic saturated polycarboxylic acids having an esterified carboxyl group bound to an acyclic carbon atom
- C07C69/38—Malonic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
"PROCESSO PARA A PREPARAçãO DE DIALQUIL FENIL MALONATOS" Um processo para a preparação de dialquil fenil malonatos de fórmula I, em que R, R¹, L¹ e L² possuem o significado dado nas reivindicações, que compreende tratamento de um fenil brometo de fórmula II com um dialquil malonato de fórmula III em um solvente inerte em presença de uma base e um sal de cobre, em que 1,0 mol do fenil brometo de fórmula II é tratado com o enolato obtido a partir de 2,0 a 4,0 moles do dialquil malonato de fórmula III e 2,0 a 3,8 moles da base.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16069598A | 1998-09-25 | 1998-09-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9904355A true BR9904355A (pt) | 2000-09-19 |
Family
ID=22578029
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9904355-6A BR9904355A (pt) | 1998-09-25 | 1999-09-23 | Processo para a preparação de dialquil fenil malonatos |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP1002788B1 (pt) |
| JP (1) | JP2000095730A (pt) |
| KR (1) | KR100619386B1 (pt) |
| CN (1) | CN1197841C (pt) |
| AT (1) | ATE261427T1 (pt) |
| BR (1) | BR9904355A (pt) |
| DE (1) | DE69915430T2 (pt) |
| DK (1) | DK1002788T3 (pt) |
| ES (1) | ES2217696T3 (pt) |
| HU (1) | HUP9903240A3 (pt) |
| IL (1) | IL131912A (pt) |
| PL (1) | PL196443B1 (pt) |
| TW (1) | TWI240721B (pt) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1373222A2 (de) | 2001-03-15 | 2004-01-02 | Basf Aktiengesellschaft | 5-phenylpyrimidine, verfahren und zwischenprodukte zu ihrer herstellung und ihre verwendung zur bekaempfung von schadpilzen |
| EP1412356A1 (en) | 2001-07-18 | 2004-04-28 | Basf Aktiengesellschaft | Substituted 6-(2-methoxyphenyl)triazolopyrimidines as fungicides |
| DE102005007534A1 (de) | 2005-02-17 | 2006-08-31 | Bayer Cropscience Ag | Pyrazolopyrimidine |
| EP2111389A1 (de) * | 2007-01-22 | 2009-10-28 | Basf Se | Verfahren zur herstellung substituierter 2-arylmalonsäureester |
| JP5129699B2 (ja) * | 2008-09-01 | 2013-01-30 | 富士フレーバー株式会社 | メチル＝ヘキサデカ−８−イノアートの製造方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2106032C (en) * | 1993-09-13 | 1995-11-07 | Gamini Weeratunga | Methods for the manufacture of fluconazole and forms thereof, intermediates useful in the manufacture thereof, and combinations comprising fluconazole |
| US5750766A (en) * | 1997-03-18 | 1998-05-12 | American Cyanamid Company | Process for the preparation of arylmalonates |
-
1999
- 1999-09-15 IL IL13191299A patent/IL131912A/xx not_active IP Right Cessation
- 1999-09-16 TW TW088115997A patent/TWI240721B/zh not_active IP Right Cessation
- 1999-09-17 KR KR1019990040039A patent/KR100619386B1/ko not_active IP Right Cessation
- 1999-09-17 JP JP11263844A patent/JP2000095730A/ja active Pending
- 1999-09-23 DE DE69915430T patent/DE69915430T2/de not_active Expired - Lifetime
- 1999-09-23 DK DK99307523T patent/DK1002788T3/da active
- 1999-09-23 ES ES99307523T patent/ES2217696T3/es not_active Expired - Lifetime
- 1999-09-23 BR BR9904355-6A patent/BR9904355A/pt not_active Application Discontinuation
- 1999-09-23 AT AT99307523T patent/ATE261427T1/de not_active IP Right Cessation
- 1999-09-23 EP EP99307523A patent/EP1002788B1/en not_active Expired - Lifetime
- 1999-09-24 HU HU9903240A patent/HUP9903240A3/hu unknown
- 1999-09-24 PL PL335599A patent/PL196443B1/pl unknown
- 1999-09-24 CN CNB991207300A patent/CN1197841C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HU9903240D0 (en) | 1999-11-29 |
| TWI240721B (en) | 2005-10-01 |
| CN1197841C (zh) | 2005-04-20 |
| EP1002788A1 (en) | 2000-05-24 |
| HUP9903240A3 (en) | 2000-11-28 |
| CN1250044A (zh) | 2000-04-12 |
| DE69915430D1 (de) | 2004-04-15 |
| EP1002788B1 (en) | 2004-03-10 |
| KR20000023255A (ko) | 2000-04-25 |
| JP2000095730A (ja) | 2000-04-04 |
| IL131912A (en) | 2005-12-18 |
| KR100619386B1 (ko) | 2006-09-06 |
| IL131912A0 (en) | 2001-03-19 |
| PL335599A1 (en) | 2000-03-27 |
| ES2217696T3 (es) | 2004-11-01 |
| HUP9903240A2 (hu) | 2000-05-28 |
| PL196443B1 (pl) | 2008-01-31 |
| ATE261427T1 (de) | 2004-03-15 |
| DE69915430T2 (de) | 2004-07-22 |
| DK1002788T3 (da) | 2004-04-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TW568896B (en) | Calcium receptor-active compounds | |
| EA199900936A1 (ru) | Фунгицидные трифторметилалкиламинотриазолопиримидины | |
| EA200500268A1 (ru) | Производные диоксан-2-алкилкарбаматов, способ их получения и применение в терапии | |
| EA200800372A1 (ru) | Соединения и их соли, специфичные к ppar рецепторам и egf рецепторам, и их применение в области медицины | |
| AR009062A1 (es) | Proceso quimico para preparar (e)-2-[2-(6-cloro-pirimidin-4-iloxi)fenil]-3- metoxi-propenato de metilo | |
| BR9904355A (pt) | Processo para a preparação de dialquil fenil malonatos | |
| DE69803271D1 (de) | Von einem aromatischen oder heteroaromatischen radikal substituierte biphenylderivate und diese enthaltende pharmaceutische und kosmetische compositionen | |
| EA200200596A1 (ru) | Окс (ади) азолилгидроксамовые кислоты, полезные в качестве ингибиторов проколлаген-с-протеиназы | |
| DE59504085D1 (de) | Eisenphosphatierung unter verwendung von substituierten monocarbonsäuren | |
| CY1107566T1 (el) | Μεθοδος για την παρασκευη r-(-)-καρνιτινης απο s-(-) χλωροηλεκτρικο οξυ ή απο ενα παραγωγο του | |
| ES2051692T3 (es) | Procedimiento para preparar 1,2,4-triazol-3-carboxamidas herbicidas. | |
| LV11691A (lv) | Panemiens 7-trialkilsililbakatina III iegusanai | |
| YU56098A (sh) | Postupak za dobijanje izvesnih aza cikloheksapeptida | |
| DE69307832T2 (de) | Verfahren zur Herstellung von substituierten Arylverbindungen | |
| BR0315112A (pt) | Sal de adição ácido, e, processo para a preparação de um composto | |
| ATE272064T1 (de) | Verfahren zur herstellung von ortho- substituierten arylmetallverbindungen und deren umsetzung mit elektrophilen | |
| SE9300013D0 (sv) | Novel process and intermediates for the preparation of prodrugs | |
| ES539161A0 (es) | Un procedimiento para preparar de rivados de azetidinona | |
| ATE256095T1 (de) | Verfahren zur c-alkylierung von aromatischen hydroxyverbindungen | |
| MY118813A (en) | Compounds and method for preparing substituted 4-phenyl-4-cyanocyclohexanoic acids | |
| DE69231314T2 (de) | SYNTHESE VON HOMOCHIRALEN 2-HYDROXYSäUREN | |
| EA199900174A1 (ru) | Способ лечения биполярного расстройства | |
| DE60110019D1 (de) | Verfahren zur Herstellung von Cyclopropancarboxylaten | |
| DE69905597D1 (de) | Verfahren zur herstellung von 4,4'-dihalogen-o-hydroxydiphenylverbindungen | |
| DE69823650D1 (de) | Azasteroidverbindung zur behandlung oder vorbeugung von prostatakrebs |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B25D | Requested change of name of applicant approved |
Owner name: WYETH HOLDINGS CORPORATION (US) Free format text: ALTERADO DE: AMERICAN CYANAMID COMPANY |
|
| B25A | Requested transfer of rights approved |
Owner name: BASF AKTIENGESELLSCHAFT (DE) Free format text: TRANSFERIDO DE: WYETH HOLDINGS CORPORATION |
|
| B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
| B15K | Others concerning applications: alteration of classification |
Free format text: ALTERADA DA INT: C07C 67/343, C07C 69/65, C07C 69/38, C07C 69/734, B01J 27/122, B01J 27/06, C07C 67/00, C07C 69/00 Ipc: C07C 67/343 (2009.01), C07C 69/65 (2009.01), C07C |
|
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O E 13 DA LPI. |
|
| B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |