SE9300013D0 - Novel process and intermediates for the preparation of prodrugs - Google Patents

Novel process and intermediates for the preparation of prodrugs

Info

Publication number
SE9300013D0
SE9300013D0 SE9300013A SE9300013A SE9300013D0 SE 9300013 D0 SE9300013 D0 SE 9300013D0 SE 9300013 A SE9300013 A SE 9300013A SE 9300013 A SE9300013 A SE 9300013A SE 9300013 D0 SE9300013 D0 SE 9300013D0
Authority
SE
Sweden
Prior art keywords
formula
salt
tranexamic acid
preparation
substituted
Prior art date
Application number
SE9300013A
Other languages
English (en)
Other versions
SE9300013L (sv
Inventor
N Aa Joensson
Original Assignee
Kabi Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kabi Pharmacia Ab filed Critical Kabi Pharmacia Ab
Priority to SE9300013A priority Critical patent/SE9300013L/sv
Publication of SE9300013D0 publication Critical patent/SE9300013D0/sv
Priority to PCT/SE1993/001115 priority patent/WO1994015904A1/en
Priority to AU58452/94A priority patent/AU5845294A/en
Publication of SE9300013L publication Critical patent/SE9300013L/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
    • C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C227/00—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C227/14—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof
    • C07C227/18—Preparation of compounds containing amino and carboxyl groups bound to the same carbon skeleton from compounds containing already amino and carboxyl groups or derivatives thereof by reactions involving amino or carboxyl groups, e.g. hydrolysis of esters or amides, by formation of halides, salts or esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
SE9300013A 1992-12-30 1992-12-30 Nytt förfarande och mellanprodukter för framställning av pro- läkemedel SE9300013L (sv)

Priority Applications (3)

Application Number Priority Date Filing Date Title
SE9300013A SE9300013L (sv) 1992-12-30 1992-12-30 Nytt förfarande och mellanprodukter för framställning av pro- läkemedel
PCT/SE1993/001115 WO1994015904A1 (en) 1992-12-30 1993-12-30 Novel process and intermediates for the preparation of prodrugs
AU58452/94A AU5845294A (en) 1992-12-30 1993-12-30 Novel process and intermediates for the preparation of prodrugs

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9300013A SE9300013L (sv) 1992-12-30 1992-12-30 Nytt förfarande och mellanprodukter för framställning av pro- läkemedel

Publications (2)

Publication Number Publication Date
SE9300013D0 true SE9300013D0 (sv) 1992-12-30
SE9300013L SE9300013L (sv) 1994-07-01

Family

ID=20388467

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9300013A SE9300013L (sv) 1992-12-30 1992-12-30 Nytt förfarande och mellanprodukter för framställning av pro- läkemedel

Country Status (3)

Country Link
AU (1) AU5845294A (sv)
SE (1) SE9300013L (sv)
WO (1) WO1994015904A1 (sv)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050025825A1 (en) 2003-07-31 2005-02-03 Xanodyne Pharmacal, Inc. Tranexamic acid formulations with reduced adverse effects
WO2005019163A2 (en) 2003-08-20 2005-03-03 Xenoport, Inc. Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
WO2005066122A2 (en) 2003-12-30 2005-07-21 Xenoport, Inc. Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
US20050244495A1 (en) 2004-03-04 2005-11-03 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US8022106B2 (en) 2004-03-04 2011-09-20 Ferring B.V. Tranexamic acid formulations
US20090215898A1 (en) 2004-03-04 2009-08-27 Xanodyne Pharmaceuticals, Inc. Tranexamic acid formulations
US7947739B2 (en) 2004-03-04 2011-05-24 Ferring B.V. Tranexamic acid formulations
CN101253148B (zh) 2005-06-20 2013-01-02 克塞诺波特公司 凝血酸的酰氧基烷基氨基甲酸酯前药，合成和使用的方法
WO2011028234A1 (en) 2009-09-04 2011-03-10 Xenoport, Inc. Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
WO2011091164A1 (en) 2010-01-22 2011-07-28 Xenoport, Inc. Oral dosage forms having a high loading of a tranexamic acid prodrug
CN116284814A (zh) * 2023-01-17 2023-06-23 杭州三式化妆品有限公司 超分子传明酸甘醇酸离子盐及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4377594A (en) * 1980-06-04 1983-03-22 Kureha Kagaku Kogyo Kabushiki Kaisha Derivative of 4-(N-(substituted-benzylidene)amino-methyl cyclohexane-1-carboxylic acid
DE3262698D1 (en) * 1981-11-17 1985-04-25 Kabivitrum Ab Antifibrinolytically active compounds

Also Published As

Publication number Publication date
AU5845294A (en) 1994-08-15
SE9300013L (sv) 1994-07-01
WO1994015904A1 (en) 1994-07-21

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