DE69231314T2 - SYNTHESE VON HOMOCHIRALEN 2-HYDROXYSäUREN - Google Patents

SYNTHESE VON HOMOCHIRALEN 2-HYDROXYSäUREN

Info

Publication number
DE69231314T2
DE69231314T2 DE69231314T DE69231314T DE69231314T2 DE 69231314 T2 DE69231314 T2 DE 69231314T2 DE 69231314 T DE69231314 T DE 69231314T DE 69231314 T DE69231314 T DE 69231314T DE 69231314 T2 DE69231314 T2 DE 69231314T2
Authority
DE
Germany
Prior art keywords
pct
salt
carboxylic acid
homochiral
nitro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69231314T
Other languages
English (en)
Other versions
DE69231314D1 (de
Inventor
Guy Casy
Victor Lee
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Euroapi UK Ltd
Original Assignee
Genzyme Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB919127249A external-priority patent/GB9127249D0/en
Priority claimed from GB929216929A external-priority patent/GB9216929D0/en
Application filed by Genzyme Ltd filed Critical Genzyme Ltd
Publication of DE69231314D1 publication Critical patent/DE69231314D1/de
Application granted granted Critical
Publication of DE69231314T2 publication Critical patent/DE69231314T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32—Oxygen atoms
    • C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/42—Hydroxy-carboxylic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69231314T 1991-12-23 1992-12-23 SYNTHESE VON HOMOCHIRALEN 2-HYDROXYSäUREN Expired - Fee Related DE69231314T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB919127249A GB9127249D0 (en) 1991-12-23 1991-12-23 Chiral synthesis
GB929216929A GB9216929D0 (en) 1992-08-10 1992-08-10 Chiral synthesis
PCT/GB1992/002396 WO1993013215A1 (en) 1991-12-23 1992-12-23 Synthesis of homochiral 2-hydroxy acids

Publications (2)

Publication Number Publication Date
DE69231314D1 DE69231314D1 (de) 2000-09-07
DE69231314T2 true DE69231314T2 (de) 2001-05-17

Family

ID=26300063

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69231314T Expired - Fee Related DE69231314T2 (de) 1991-12-23 1992-12-23 SYNTHESE VON HOMOCHIRALEN 2-HYDROXYSäUREN

Country Status (12)

Country Link
US (1) US5686275A (de)
EP (1) EP0620857B1 (de)
JP (1) JP3228513B2 (de)
AT (1) ATE195145T1 (de)
AU (1) AU663549B2 (de)
CA (1) CA2117340C (de)
DE (1) DE69231314T2 (de)
DK (1) DK0620857T3 (de)
ES (1) ES2148215T3 (de)
GR (1) GR3034120T3 (de)
PT (1) PT620857E (de)
WO (1) WO1993013215A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9413710D0 (en) * 1994-07-07 1994-08-24 Genzyme Ltd Chiral synthesis
US20040053382A1 (en) * 2000-10-17 2004-03-18 Senkpeil Richard F. Production of alpha-hydroxy-carboxylic acids using a coupled enzyme system
DE10300335B4 (de) * 2003-01-09 2008-06-26 Iep Gmbh Oxidoreduktase
US8067398B2 (en) * 2005-06-01 2011-11-29 Yissum Research Development Company Of The Hebrew University Of Jerusalem Biodegradable polymers having a pre-determined chirality
JPWO2008018520A1 (ja) * 2006-08-09 2010-01-07 株式会社カネカ 光学活性ヒドロキシカルボン酸誘導体又はその塩の製造法
FR3033166B1 (fr) 2015-02-27 2017-03-10 Afyren Procede de production d'acides amines a partir de precurseurs obtenus par fermentation anaerobie a partir de biomasse fermentescible
FR3033168B1 (fr) * 2015-02-27 2017-03-10 Afyren Procede de production de polyhydroxyalcanoates a partir de precurseurs obtenus par fermentation anaerobie a partir de biomasse fermentescible

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0394448B1 (de) * 1988-02-08 1996-05-01 Daicel Chemical Industries, Ltd. Verfahren zur herstellung optisch aktiver 2-hydroxy-4-phenylbutansäure
ATE98697T1 (de) * 1988-06-06 1994-01-15 Ciba Geigy Ag Verfahren zur herstellung von hydroxysaeuren.
EP0380689B1 (de) * 1988-07-12 1995-10-04 Daicel Chemical Industries, Ltd. Verfahren zur herstellung optisch aktiver 2-hydroxy-4-phenyl-3-butensäure
ES2055779T3 (es) * 1988-11-28 1994-09-01 Ciba Geigy Ag Biocatalizadores y procedimientos para su obtencion.
AT398081B (de) * 1991-04-29 1994-09-26 Chemie Linz Gmbh Verfahren zur enzymatischen hydrolyse eines carbonsäurederivates
CA2121972A1 (en) * 1993-05-06 1994-11-07 Konrad Lerch Substituted valeric acid

Also Published As

Publication number Publication date
WO1993013215A1 (en) 1993-07-08
EP0620857A1 (de) 1994-10-26
PT620857E (pt) 2000-12-29
US5686275A (en) 1997-11-11
JP3228513B2 (ja) 2001-11-12
ES2148215T3 (es) 2000-10-16
JPH07502410A (ja) 1995-03-16
DE69231314D1 (de) 2000-09-07
AU663549B2 (en) 1995-10-12
ATE195145T1 (de) 2000-08-15
AU3169593A (en) 1993-07-28
DK0620857T3 (da) 2000-10-09
GR3034120T3 (en) 2000-11-30
CA2117340A1 (en) 1993-07-08
EP0620857B1 (de) 2000-08-02
CA2117340C (en) 2003-06-10

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Legal Events

Date Code Title Description
8332 No legal effect for de
8370 Indication related to discontinuation of the patent is to be deleted
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee