HUT49838A - Process for producing optical isomers of 2-(3,4-disubstituted phenyl)-3-methylbutyric acids and their esters - Google Patents

Process for producing optical isomers of 2-(3,4-disubstituted phenyl)-3-methylbutyric acids and their esters

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Publication number
HUT49838A
HUT49838A HU237388A HU237388A HUT49838A HU T49838 A HUT49838 A HU T49838A HU 237388 A HU237388 A HU 237388A HU 237388 A HU237388 A HU 237388A HU T49838 A HUT49838 A HU T49838A
Authority
HU
Hungary
Prior art keywords
esters
phenyl
optical isomers
acids
hydroxy
Prior art date
Application number
HU237388A
Other languages
Hungarian (hu)
Other versions
HU203068B (en
Inventor
Laszlo Szabo
Ferenc Faigl
Elemer Fogassy
Laszlo Csiz
Original Assignee
Budapesti Mueszaki Egyetem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Budapesti Mueszaki Egyetem filed Critical Budapesti Mueszaki Egyetem
Priority to HU237388A priority Critical patent/HU203068B/en
Publication of HUT49838A publication Critical patent/HUT49838A/en
Publication of HU203068B publication Critical patent/HU203068B/en

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Abstract

2-(3,4-di: substd-phenyl) -3-methyl-butyne acid and its optical isomers of formula (I) and their esters, - R1 and R2 are independently methoxy, ethoxy or hydroxy gps. - are prepd. as follows: (a) For R1 and R2 to be methoxy or ethoxy substituents 2-(3,4-disubstd-phenyl) -3-methyl-butyro-nitrile of formula (II) is hydrolized in alkaline medium and the prod. reacts with racemic or optically active 1-phenyl-ethyl-amine of its hydrochloride, still in the reaction mix or following its isolation. (B) In order that R1 and R2 should be hydroxy hydroxy substituents (II) is acid hydrolized and the prod. reacts with 1-phenyl ethyl-amine as in (a). Following prepn. purification may be carried out by recrystallization and isolation of the racemic or optically active acids; Opt. the esters of these acids may be
HU237388A 1988-05-11 1988-05-11 Process for producing 2-(3,4-disubsituted phenyl)-3-mehtylbutyric acids, their optical isomers, as well as alpha-cyano-m-phenoxybenzyl esters HU203068B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
HU237388A HU203068B (en) 1988-05-11 1988-05-11 Process for producing 2-(3,4-disubsituted phenyl)-3-mehtylbutyric acids, their optical isomers, as well as alpha-cyano-m-phenoxybenzyl esters

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU237388A HU203068B (en) 1988-05-11 1988-05-11 Process for producing 2-(3,4-disubsituted phenyl)-3-mehtylbutyric acids, their optical isomers, as well as alpha-cyano-m-phenoxybenzyl esters

Publications (2)

Publication Number Publication Date
HUT49838A true HUT49838A (en) 1989-11-28
HU203068B HU203068B (en) 1991-05-28

Family

ID=10959038

Family Applications (1)

Application Number Title Priority Date Filing Date
HU237388A HU203068B (en) 1988-05-11 1988-05-11 Process for producing 2-(3,4-disubsituted phenyl)-3-mehtylbutyric acids, their optical isomers, as well as alpha-cyano-m-phenoxybenzyl esters

Country Status (1)

Country Link
HU (1) HU203068B (en)

Also Published As

Publication number Publication date
HU203068B (en) 1991-05-28

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee