BR9813249A - Peptìdeos derivados de mamìferos para tratamento de injeção microbiana - Google Patents

Peptìdeos derivados de mamìferos para tratamento de injeção microbiana

Info

Publication number
BR9813249A
BR9813249A BR9813249-0A BR9813249A BR9813249A BR 9813249 A BR9813249 A BR 9813249A BR 9813249 A BR9813249 A BR 9813249A BR 9813249 A BR9813249 A BR 9813249A
Authority
BR
Brazil
Prior art keywords
alpha
beta chains
bacteria
compositions
mammalian
Prior art date
Application number
BR9813249-0A
Other languages
English (en)
Inventor
Brian F Hoffman
Bernard Dubnick
Original Assignee
Theragem Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theragem Inc filed Critical Theragem Inc
Publication of BR9813249A publication Critical patent/BR9813249A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00—Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50—Isolated enzymes; Isolated proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/41—Porphyrin- or corrin-ring-containing peptides
    • A61K38/42—Haemoglobins; Myoglobins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
    • A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
    • A61L2/0088—Liquid substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18—Liquid substances or solutions comprising solids or dissolved gases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Pest Control & Pesticides (AREA)
  • Communicable Diseases (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Agronomy & Crop Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Environmental Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Patente de Invenção: "PEPTìDEOS DERIVADOS DE MAMìFEROS PARA O TRATAMENTO DE INFECçãO MICROBIANA". A presente invenção fornece composições úteis como agentes antimicrobianos que incluem hemoglobina de mamíferos, cadeias <244> e <225> de hemoglobina isentas de heme, fragmentos das cadeias <244> e <225> que resultam da clivagem com brometo de cianogênio das cadeias <244> e <225>, e peptídeos sintéticos derivados das mesmas. As composições exercem atividade anti-microbiana contra bactérias e fungos comparável à de peptídeos antimicrobianos conhecidos, obtidos de neutrófilos de seres humanos, catepsina G e azurocidina. Dentre os organismos sensíveis estão bactérias Gram-nega-tivas como Escherichia coli e Pseudomonas aeruginosa, bactérias Gram-positivas como Staphylococcus aureus e Streptococcus faecalis e o fungo Candida albicans. Métodos para a preparação das composições são também fornecidos.
BR9813249-0A 1997-10-08 1998-08-10 Peptìdeos derivados de mamìferos para tratamento de injeção microbiana BR9813249A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6145497P 1997-10-08 1997-10-08
PCT/US1998/016746 WO1999017786A1 (en) 1997-10-08 1998-08-10 Mammalian-derived peptides for the treatment of microbial infection

Publications (1)

Publication Number Publication Date
BR9813249A true BR9813249A (pt) 2002-02-19

Family

ID=22035890

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9813249-0A BR9813249A (pt) 1997-10-08 1998-08-10 Peptìdeos derivados de mamìferos para tratamento de injeção microbiana

Country Status (12)

Country Link
US (1) US6337314B1 (pt)
EP (1) EP1066045B1 (pt)
CN (1) CN1280497A (pt)
AT (1) ATE285786T1 (pt)
AU (1) AU750614B2 (pt)
BR (1) BR9813249A (pt)
CA (1) CA2309554A1 (pt)
DE (1) DE69828443T2 (pt)
EA (1) EA002242B1 (pt)
ES (1) ES2236931T3 (pt)
NZ (1) NZ504405A (pt)
WO (1) WO1999017786A1 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001094386A2 (de) * 2000-06-08 2001-12-13 Ipf Pharmaceuticals Gmbh Verfahren zur gewinnung und anwendung von antibiotisch wirksamen peptiden zur behandlung von infektionskrankheiten
US7655242B2 (en) * 2002-12-13 2010-02-02 Case Western Reserve University Defensin-inducing agents
FR2854801B1 (fr) * 2003-05-12 2006-09-01 Khorionyx Implant injectable de globine insoluble
US6949625B2 (en) 2003-05-12 2005-09-27 Khorionyx Injectable implant of insoluble globin
EP1778271B1 (en) * 2004-08-18 2008-10-22 IPF Pharmaceuticals GmbH Peptides for the treatment of herpes virus infections
JPWO2006073119A1 (ja) * 2005-01-06 2008-06-12 公立大学法人県立広島大学 ポリペプチドおよびその用途
US20120183501A1 (en) 2010-11-12 2012-07-19 Jean-Louis Tayot Novel method for treatment of skin wounds and preparations for implementation of same
TR201809571T4 (tr) 2013-03-15 2018-07-23 Hoffmann La Roche Ll-22 polipeptidleri ile ıl-22 fc füzyon proteinleri ve kullanım yöntemleri.
CN103141846A (zh) * 2013-03-26 2013-06-12 四川省石棉县田湾河野生资源开发有限公司 鸡血红素微胶囊及其制作方法
CN103948632B (zh) * 2014-05-07 2018-03-13 沈阳药科大学 蟾饲五谷虫抗菌肽的医药用途
WO2017167763A1 (en) * 2016-03-29 2017-10-05 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for diagnosis of haemorrhagic atherothrombotic plaques
CN113621055B (zh) * 2021-08-23 2023-05-02 山东仙普爱瑞科技股份有限公司 一种抗菌和抗病毒的猪血红蛋白β链C端片段、表达该片段的枯草芽孢杆菌、制剂以及应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2523052A1 (de) * 1975-05-24 1976-12-02 Toni Dr Dockner Verfahren zur bekaempfung von pathogenen pilzen
US4704364A (en) 1984-05-18 1987-11-03 Coulter Electronics, Inc. Hematology control compositions for three populations of leukocytes; and methods for their preparation and use in whole blood control systems
DE3438966A1 (de) * 1984-10-24 1986-04-24 Oxo Chemie GmbH, 6900 Heidelberg Zubereitung zur freisetzung aktivierten sauerstoffes und deren verwendung
US5239061A (en) * 1990-06-20 1993-08-24 Research Corporation Technologies, Inc. Modified human hemoglobin, blood substitutes containing the same, and vectors for expressing the modified hemoglobin
US5370869A (en) * 1990-09-04 1994-12-06 Shanbrom; Edward Antimicrobial preservation of platelets and blood factors
JPH05305126A (ja) * 1991-01-24 1993-11-19 Nippon Oil & Fats Co Ltd 殺菌方法
WO1993008831A1 (en) * 1991-10-30 1993-05-13 Strohtech, Inc. Expression of recombinant hemoglobin and hemoglobin variants in yeast

Also Published As

Publication number Publication date
AU8781098A (en) 1999-04-27
US6337314B1 (en) 2002-01-08
ES2236931T3 (es) 2005-07-16
ATE285786T1 (de) 2005-01-15
EA002242B1 (ru) 2002-02-28
CA2309554A1 (en) 1999-04-15
CN1280497A (zh) 2001-01-17
NZ504405A (en) 2002-09-27
AU750614B2 (en) 2002-07-25
EA200000407A1 (ru) 2000-10-30
WO1999017786A1 (en) 1999-04-15
DE69828443T2 (de) 2006-06-01
EP1066045A4 (en) 2001-05-16
EP1066045A1 (en) 2001-01-10
DE69828443D1 (de) 2005-02-03
EP1066045B1 (en) 2004-12-29

Similar Documents

Publication Publication Date Title
ATE217885T1 (de) Antimikrobielle polypeptide
BR9205760A (pt) Proteínas antimicrobiais, proteína pura MJ-AMPI, proteínas puras, sequência de DNA recombinante, vetor, sistema biológico, plantas, composição antimicrobial, processo para combater fungos ou bactérias e processo de extração para produzir proteínas biocidamente ativas
BR9813249A (pt) Peptìdeos derivados de mamìferos para tratamento de injeção microbiana
KR950702640A (ko) 감염증 진단용 프로브
BR9609281A (pt) Método para o controle de bactérias gram-positivas resistentes a antibióticos e tratamento de infecções
ATE543831T1 (de) Antibakterielle wirkstoffe enthaltende konjugate von glykopeptiden und membranassoziierenden peptiden
WO2003037259A3 (en) Methods for the prevention or treatment of bacterial and fungal infections
EP1037650A4 (en) METHODS AND COMPOSITIONS FOR THE TREATMENT AND PREVENTION OF STAPHYLOCOCCUS AUREUS INFECTIONS
BRPI0411534A (pt) derivados de lincomicina com atividade antimicrobiana
DE69405887D1 (de) Fungizide Mittel zur Verhinderung des Wachstums des Schimmels bei Lebensmitteln und landwirtschaftlichen Produkten
DE69434071D1 (de) Antimikrobielle proteine
EA200500353A1 (ru) Производные линкомицина, обладающие антибактериальной активностью
BR9914398A (pt) Compostos de hidroxiestilbeno enquanto agentes microbicidas
WO1999015548A3 (en) Isolated and recombinant antimicrobial peptides thrombocidin-1 (tc-1) and thrombocidin-2 (tc-2) or variants thereof
BR9206105A (pt) Proteínas antimicrobianas puras, codificação de sequência de DNA recombinante para uma proteína, vetor contendo uma sequência DNA, sistema biológico incluindo DNA, plantas transformadas com DNA recombinante, proteína derivada da transmissão do DNA processo de extracão para a produção de proteínas biocidamente ativas, processo de combate de fungos ou de bactérias, e, composição antimicrobiana contendo uma ou mais das proteínas
HUP0401586A2 (hu) Baktériumellenes szer
Sharma et al. New generation antibiotics/antibacterials: Deadly arsenal for disposal of antibiotic resistant bacteria
BR9813355A (pt) Peptìdeos derivados de répteis para o tratamento de infecção microbiana
WO2002040536A3 (en) Acylated antimicrobial peptides
HUP0002920A2 (hu) Staphylococcus aureus terápia
BR9611759A (pt) Processo para o tratamento ou prevenção de mucosite oral em um animal, e, composição para administração oral tópica de um peptìdeo antimicrobiano
FR2841903B1 (fr) Nouveau peptide de plante a activite anti-microbienne
Mahmoud et al. ANTIMICROBIAL ACTIVITY OF SECRETORY MATERIALS OF SOME SCALE INSECTS.
DE59801718D1 (de) Verwendung von escherichia coli stamm dsm 6601 zur behandlung von diarrhoeen auf dem veterinärsektor
EA200501830A1 (ru) Новые производные линкомицина, обладающие антимикробной активностью

Legal Events

Date Code Title Description
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: O DEPOSITANTE DEIXOU DE APRESENTAR MANIFESTACAO SOBRE O PARECER NEGATIVO DE FOLHAS 161 A 164 PUBLICADO NA RPI N.O 1975, DE 11/11/2008. ASSIM, DE ACORDO COM O ART. 36 DA LPI (LEI 9279/96) 2O, O PEDIDO VOLTA A EXAME SENDO CONSIDERADO NAO PATENTEAVEL PELAS RAZOES EXPOSTAS NO PARECER TECNICO ANTERIOR. PORTANTO, INDEFIRO O PRESENTE PEDIDO.

B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL.