BR9806954A - Receptores 6a e 6b do fator de necrose tumoral - Google Patents

Receptores 6a e 6b do fator de necrose tumoral

Info

Publication number
BR9806954A
BR9806954A BR9806954A BR9806954A BR9806954A BR 9806954 A BR9806954 A BR 9806954A BR 9806954 A BR9806954 A BR 9806954A BR 9806954 A BR9806954 A BR 9806954A BR 9806954 A BR9806954 A BR 9806954A
Authority
BR
Brazil
Prior art keywords
tnfr
necrosis factor
tumor necrosis
methods
receptors
Prior art date
Application number
BR9806954A
Other languages
English (en)
Portuguese (pt)
Inventor
Reiner L Gentz
Guo-Liang Yu
Steven M Ruben
Jian Ni
Reinhard Ebner
Ping Feng
Original Assignee
Human Genome Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21883066&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR9806954(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Human Genome Sciences Inc filed Critical Human Genome Sciences Inc
Publication of BR9806954A publication Critical patent/BR9806954A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Cell Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR9806954A 1997-01-14 1998-01-13 Receptores 6a e 6b do fator de necrose tumoral BR9806954A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US3549697P 1997-01-14 1997-01-14
PCT/US1998/000153 WO1998030694A2 (en) 1997-01-14 1998-01-13 TUMOR NECROSIS FACTOR RECEPTORS 6α AND 6$g(b)

Publications (1)

Publication Number Publication Date
BR9806954A true BR9806954A (pt) 2000-03-21

Family

ID=21883066

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9806954A BR9806954A (pt) 1997-01-14 1998-01-13 Receptores 6a e 6b do fator de necrose tumoral

Country Status (12)

Country Link
US (2) US8003386B1 (cg-RX-API-DMAC7.html)
EP (1) EP1007659B1 (cg-RX-API-DMAC7.html)
JP (1) JP2001507937A (cg-RX-API-DMAC7.html)
KR (1) KR20000070174A (cg-RX-API-DMAC7.html)
CN (1) CN1247567A (cg-RX-API-DMAC7.html)
AT (1) ATE365796T1 (cg-RX-API-DMAC7.html)
AU (1) AU729062C (cg-RX-API-DMAC7.html)
BR (1) BR9806954A (cg-RX-API-DMAC7.html)
CA (1) CA2277925A1 (cg-RX-API-DMAC7.html)
DE (1) DE69837996T2 (cg-RX-API-DMAC7.html)
ES (1) ES2286843T3 (cg-RX-API-DMAC7.html)
WO (1) WO1998030694A2 (cg-RX-API-DMAC7.html)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7597886B2 (en) 1994-11-07 2009-10-06 Human Genome Sciences, Inc. Tumor necrosis factor-gamma
US7429646B1 (en) 1995-06-05 2008-09-30 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor-like 2
US7888466B2 (en) 1996-01-11 2011-02-15 Human Genome Sciences, Inc. Human G-protein chemokine receptor HSATU68
US7357927B2 (en) 1996-03-12 2008-04-15 Human Genome Sciences, Inc. Death domain containing receptors
US6713061B1 (en) 1996-03-12 2004-03-30 Human Genome Sciences, Inc. Death domain containing receptors
WO1997033904A1 (en) 1996-03-12 1997-09-18 Human Genome Sciences, Inc. Death domain containing receptors
US7964190B2 (en) 1996-03-22 2011-06-21 Human Genome Sciences, Inc. Methods and compositions for decreasing T-cell activity
US6635743B1 (en) 1996-03-22 2003-10-21 Human Genome Sciences, Inc. Apoptosis inducing molecule II and methods of use
US7285267B2 (en) 1997-01-14 2007-10-23 Human Genome Sciences, Inc. Tumor necrosis factor receptors 6α & 6β
CN1247567A (zh) 1997-01-14 2000-03-15 人体基因组科学有限公司 肿瘤坏死因子受体6α和6β
WO1999004001A1 (en) * 1997-07-21 1999-01-28 Zymogenetics, Inc. Tumor necrosis factor receptor ztnfr-5
WO1999007738A2 (en) * 1997-08-06 1999-02-18 Regeneron Pharmaceuticals, Inc. Human orphan receptor ntr-1
AU9376498A (en) * 1997-09-05 1999-03-22 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
IL134578A0 (en) * 1997-09-18 2001-04-30 Genentech Inc DcR3 POLYPEPTIDE, A TNFR HOMOLOG
WO1999026977A1 (en) * 1997-11-24 1999-06-03 Biogen, Inc. Novel receptors opg-2
JP2002508168A (ja) * 1997-12-16 2002-03-19 インサイト・ファーマスーティカルズ・インコーポレイテッド ヒト腫瘍壊死因子ｒ２様タンパク質
DE19809978A1 (de) * 1998-03-09 1999-09-16 Basf Ag Neuer Rezeptor aus der menschlichen Lunge
CZ20003433A3 (cs) * 1998-03-30 2001-10-17 Eli Lilly And Company Terapeutické aplikace zralých FLINT (mFLINT) polypeptidů nebo OPG3, které jsou členy nadskupiny receptorů TNF
US6916907B1 (en) * 1998-10-23 2005-07-12 Curagen Corporation Nucleic acids encoding osteoprotegern-like proteins and methods of using same
AU2164400A (en) * 1998-12-09 2000-06-26 Eli Lilly And Company Flint compositions and uses thereof
WO2000037094A2 (en) * 1998-12-22 2000-06-29 Eli Lilly And Company Therapeutic applications of flint polypeptides
WO2000046247A1 (en) * 1999-02-05 2000-08-10 Merck & Co., Inc. Methods of use for dna molecules encoding m68, a tnf receptor-related protein
JP2002537769A (ja) 1999-02-26 2002-11-12 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド ヒトエンドカインαおよび使用方法
EP1159286A4 (en) * 1999-03-04 2003-01-15 Human Genome Sciences Inc TUMOR NECROSIS FACTOR RECEPTORS 6 ALPHA AND 6 BETA
AU2495200A (en) * 1999-03-08 2000-09-28 Genentech Inc. Compositions and methods for the treatment of tumor
US6835814B1 (en) 1999-03-30 2004-12-28 Eli Lilly And Company Protease resistant flint analogs
AU3739500A (en) * 1999-03-30 2000-10-16 Eli Lilly And Company Protease resistant flint analogs
US6965012B1 (en) * 1999-03-30 2005-11-15 Eli Lilly And Company Flint polypeptide analogs
JP2002539828A (ja) * 1999-03-30 2002-11-26 イーライ・リリー・アンド・カンパニー Ｆｌｉｎｔポリペプチドアナログ
US6627199B1 (en) 1999-07-09 2003-09-30 Amgen Inc Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family
WO2001010908A1 (en) * 1999-08-04 2001-02-15 Amgen Inc. Ntr3, a member of the tnf-receptor supergene family
JP2003506088A (ja) 1999-08-04 2003-02-18 アムジェン インコーポレーテッド ＴＮＦリガンドスーパー遺伝子ファミリーの新規のメンバーであるＦｈｍ
WO2001018055A1 (en) * 1999-09-10 2001-03-15 Eli Lilly And Company Flint analog compounds and formulations thereof
WO2001018041A2 (en) * 1999-09-10 2001-03-15 Eli Lilly And Company Flint proteins and formulations thereof
WO2001018202A2 (en) * 1999-09-10 2001-03-15 Eli Lilly And Company Flint analog compounds and formulations thereof
WO2001096528A2 (en) 2000-06-15 2001-12-20 Human Genome Sciences, Inc. Human tumor necrosis factor delta and epsilon
WO2002002641A1 (en) 2000-06-16 2002-01-10 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to blys
CN1331125A (zh) * 2000-06-26 2002-01-16 上海博德基因开发有限公司 一种新的多肽——人含细胞色素c结构域的tnfr/ngfr蛋白9.02和编码这种多肽的多核苷酸
EP1322667A4 (en) * 2000-08-25 2004-08-18 Human Genome Sciences Inc TUMOR NECROSIS FACTOR RECEPTORS 6-ALPHA AND 6-BETA
ES2437992T3 (es) 2001-05-25 2014-01-15 Human Genome Sciences, Inc. Anticuerpos que se unen inmunoespecíficamente a los receptores de TRAIL
EP2261250B1 (en) 2001-12-21 2015-07-01 Human Genome Sciences, Inc. GCSF-Albumin fusion proteins
JP5303092B2 (ja) 2002-09-11 2013-10-02 ジェネンテック， インコーポレイテッド タンパク質精製
JP5905184B2 (ja) 2005-10-13 2016-04-20 ヒューマン ジノーム サイエンシーズ， インコーポレイテッドＨｕｍａｎ Ｇｅｎｏｍｅ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． 自己抗体陽性疾患を有する患者の処置に使用するための方法および組成物
US20090269345A1 (en) * 2005-12-23 2009-10-29 Rong Fan CLN248 Antibody Compositions and Methods of Use
US20110229471A1 (en) 2008-11-26 2011-09-22 Cedars-Sinai Medical Center Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease
EP2406388B1 (en) * 2009-03-13 2016-09-28 The Trustees Of The University Of Pennsylvania Ox40/trail fusion proteins
CN103874707B (zh) 2010-11-19 2017-04-19 卫材R&D管理有限公司 中和抗‑ccl20抗体
CA2908553A1 (en) 2013-03-27 2014-10-02 Cedars-Sinai Medical Center Mitigation and reversal of fibrosis and inflammation by inhibition of tl1a function and related signaling pathways
CA2927309A1 (en) 2013-05-24 2014-11-27 Promis Neurosciences Inc. Fasr antibodies for diagnostic and therapeutic use
EP4105236A1 (en) 2013-07-19 2022-12-21 Cedars-Sinai Medical Center Anti-tl1a (tnfsf15) antibody for treatment of inflammatory bowel disease
JP7082945B2 (ja) 2016-03-17 2022-06-09 シーダーズ―シナイ メディカル センター Ｒｎａｓｅｔ２により炎症性腸疾患を診断する方法

Family Cites Families (48)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4847325A (en) * 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
US5194596A (en) * 1989-07-27 1993-03-16 California Biotechnology Inc. Production of vascular endothelial cell growth factor
US5350836A (en) * 1989-10-12 1994-09-27 Ohio University Growth hormone antagonists
CA2067031C (en) 1991-04-26 2003-02-18 Shigekazu Nagata Dna coding for human cell surface antigen
JPH09503672A (ja) 1993-10-14 1997-04-15 イミュネックス・コーポレーション Ｆａｓ拮抗剤とその利用
US5830469A (en) 1993-10-14 1998-11-03 Immunex Corporation Fas antagonists and uses thereof
US5663070A (en) 1993-11-15 1997-09-02 Lxr Biotechnology Inc. Recombinant production of a soluble splice variant of the Fas (Apo-1) antigen, fas TM
US5741667A (en) 1994-05-27 1998-04-21 Genentech, Inc. Tumor necrosis factor receptor-associated factors
US5632994A (en) 1994-06-14 1997-05-27 La Jolla Cancer Research Foundation Fas associated proteins
WO2000032221A2 (en) 1998-12-01 2000-06-08 Genentech, Inc. Promotion or inhibition of angiogenesis and cardiovascularization
EP2017337A1 (en) 1995-04-27 2009-01-21 Human Genome Sciences, Inc. Human tumor necrosis factor receptors
US5985614A (en) * 1996-08-30 1999-11-16 Human Genome Sciences, Inc. Polynucleotides encoding interleukin-19
CN1247567A (zh) 1997-01-14 2000-03-15 人体基因组科学有限公司 肿瘤坏死因子受体6α和6β
US5885800A (en) 1997-02-04 1999-03-23 Smithkline Beecham Corporation DNA encoding tumor necrosis related receptor, TR4
WO1998056892A1 (en) 1997-06-11 1998-12-17 Human Genome Sciences, Inc. Human tumor necrosis factor receptor tr9
WO1999004001A1 (en) 1997-07-21 1999-01-28 Zymogenetics, Inc. Tumor necrosis factor receptor ztnfr-5
WO1999007738A2 (en) 1997-08-06 1999-02-18 Regeneron Pharmaceuticals, Inc. Human orphan receptor ntr-1
AU9376498A (en) 1997-09-05 1999-03-22 University Of Washington Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents
IL134578A0 (en) 1997-09-18 2001-04-30 Genentech Inc DcR3 POLYPEPTIDE, A TNFR HOMOLOG
WO1999026977A1 (en) 1997-11-24 1999-06-03 Biogen, Inc. Novel receptors opg-2
JP2002508168A (ja) 1997-12-16 2002-03-19 インサイト・ファーマスーティカルズ・インコーポレイテッド ヒト腫瘍壊死因子ｒ２様タンパク質
AU2093499A (en) 1997-12-30 1999-07-19 Chiron Corporation Members of tnf and tnfr families
US6297367B1 (en) 1997-12-30 2001-10-02 Chiron Corporation Polynucleotide encoding TNFL1
DE19809978A1 (de) 1998-03-09 1999-09-16 Basf Ag Neuer Rezeptor aus der menschlichen Lunge
CZ20003433A3 (cs) 1998-03-30 2001-10-17 Eli Lilly And Company Terapeutické aplikace zralých FLINT (mFLINT) polypeptidů nebo OPG3, které jsou členy nadskupiny receptorů TNF
JP2002519062A (ja) 1998-07-06 2002-07-02 シェーリング コーポレイション 哺乳動物遺伝子；樹状細胞プロスタグランジン様トランスポーター（ｄｃ−ｐｇｔ）、ｈｄｔｅａ，ｈｓｌｊｄ３７ｒおよびｒａｎｋｌ、ｈｃｃ５ケモカイン、脱ユビキチン化１１および１２（ｄｕｂ１１、ｄｕｂ１２）、ｍｄ−１、ｍｄ−２およびサイクリンｅ２、関連試薬および方法
AU2164400A (en) 1998-12-09 2000-06-26 Eli Lilly And Company Flint compositions and uses thereof
WO2000037094A2 (en) 1998-12-22 2000-06-29 Eli Lilly And Company Therapeutic applications of flint polypeptides
WO2000046247A1 (en) 1999-02-05 2000-08-10 Merck & Co., Inc. Methods of use for dna molecules encoding m68, a tnf receptor-related protein
EP1159286A4 (en) 1999-03-04 2003-01-15 Human Genome Sciences Inc TUMOR NECROSIS FACTOR RECEPTORS 6 ALPHA AND 6 BETA
CA2362427A1 (en) 1999-03-08 2000-09-14 Genentech, Inc. Compositions and methods for the treatment of immune related diseases
AU2495200A (en) 1999-03-08 2000-09-28 Genentech Inc. Compositions and methods for the treatment of tumor
WO2000053223A1 (en) 1999-03-11 2000-09-14 Human Genome Sciences, Inc. Apoptosis inducing molecule ii and methods of use
JP2002539828A (ja) 1999-03-30 2002-11-26 イーライ・リリー・アンド・カンパニー Ｆｌｉｎｔポリペプチドアナログ
AU3739500A (en) 1999-03-30 2000-10-16 Eli Lilly And Company Protease resistant flint analogs
WO2001022920A2 (en) 1999-09-29 2001-04-05 Human Genome Sciences, Inc. Colon and colon cancer associated polynucleotides and polypeptides
AU1189101A (en) 1999-10-20 2001-04-30 Eli Lilly And Company Therapeutic applications of flint polypeptides
AU1915201A (en) 1999-12-07 2001-06-18 Eli Lilly And Company Improving stability of flint through o-linked glycosylation
EP1240311A1 (en) 1999-12-09 2002-09-18 Merck & Co., Inc. Dna molecules encoding human nhl, a dna helicase
US20040048254A1 (en) 2000-03-15 2004-03-11 Alexander Olek Diagnosis of diseases associated with tumor supressor genes and oncogenes
WO2002000677A1 (en) 2000-06-07 2002-01-03 Human Genome Sciences, Inc. Nucleic acids, proteins, and antibodies
EP1294947A2 (en) 2000-06-30 2003-03-26 Epigenomics AG Method and nucleic acids for pharmacogenomic methylation analysis
WO2002009668A2 (en) 2000-08-02 2002-02-07 Eli Lilly And Company Pulmonary administration of flint
US20030073144A1 (en) 2001-01-30 2003-04-17 Corixa Corporation Compositions and methods for the therapy and diagnosis of pancreatic cancer
AU2002246967A1 (en) 2001-02-01 2002-08-12 Eli Lilly And Company Glycoforms a fas ligand inhibitory protein analog
US20040176279A1 (en) 2001-02-01 2004-09-09 Nigel Jenkins Flint glycoforms
US20040236091A1 (en) 2001-03-28 2004-11-25 Chicz Roman M. Translational profiling
FR2908832B1 (fr) 2006-11-20 2011-08-26 Valeo Systemes Thermiques Carter pour echangeur de chaleur

Also Published As

Publication number Publication date
US7186800B1 (en) 2007-03-06
WO1998030694A2 (en) 1998-07-16
EP1007659A2 (en) 2000-06-14
CA2277925A1 (en) 1998-07-16
KR20000070174A (ko) 2000-11-25
DE69837996D1 (de) 2007-08-09
CN1247567A (zh) 2000-03-15
ATE365796T1 (de) 2007-07-15
AU5815798A (en) 1998-08-03
DE69837996T2 (de) 2008-02-28
US8003386B1 (en) 2011-08-23
JP2001507937A (ja) 2001-06-19
AU729062B2 (en) 2001-01-25
WO1998030694A3 (en) 1998-11-12
EP1007659B1 (en) 2007-06-27
AU729062C (en) 2004-03-25
ES2286843T3 (es) 2007-12-01

Similar Documents

Publication Publication Date Title
BR9806954A (pt) Receptores 6a e 6b do fator de necrose tumoral
WO1998031806A3 (en) Fc receptors and polypeptides
DE69841140D1 (de) Interleukin-17 rezeptor-ähnliches protein
DE69635088D1 (de) NEUTROKIN alpha
NZ510367A (en) Interleukin 17-like receptor protein nucleic acid sequence encoding the interleukin receptor protein and method of expressing protein in recombinant vector
WO1998031818A3 (en) Tace-like and matrilysin-like polypeptides
WO2001055307A8 (en) Nucleic acids, proteins, and antibodies
DE69836956D1 (de) Rezeptor 5, der eine für den zelltod verantwortliche domäne enthält
WO2001054472A3 (en) Nucleic acids, proteins, and antibodies
HK1042498A1 (zh) 肿瘤坏死因子受体6α及6β
WO2000067793A8 (en) Death domain containing receptor 4
WO2003083078A3 (en) Novel human cell surface protein with immunoglobulin folds, bgs-19
ATE472599T1 (de) Chemokin alpha-5
EP1187842A4 (en) THE TR10 RECEPTOR OF THE HUMAN TUMOR NECROSE FACTOR
WO2002018622A3 (en) TUMOR NECROSIS FACTOR RECEPTORS 6α AND 6$g(b)
DE60120507D1 (de) Menschliches leucinereiche wiederholungen enthaltendes protein, vorwiegend im dünndarm exprimiert, hlrrsi1
WO2001032128A3 (en) Human chemokine beta-13
WO2001005834A9 (en) Human tumor necrosis factor receptors tr13 and tr14
WO2000039136A3 (en) Human brainiac-5
EP1712631A3 (en) Fc receptors and polypeptides
WO2002057421A3 (en) Human tumor necrosis factor receptors tr13 and tr14
WO2001055162A8 (en) Nucleic acids, proteins, and antibodies

Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 9A E 10A ANUIDADES.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1928 DE 18/12/2007.