CA2277925A1 - Tumor necrosis factor receptors 6.alpha. and 6.beta. - Google Patents
Tumor necrosis factor receptors 6.alpha. and 6.beta. Download PDFInfo
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- CA2277925A1 CA2277925A1 CA002277925A CA2277925A CA2277925A1 CA 2277925 A1 CA2277925 A1 CA 2277925A1 CA 002277925 A CA002277925 A CA 002277925A CA 2277925 A CA2277925 A CA 2277925A CA 2277925 A1 CA2277925 A1 CA 2277925A1
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Cell Biology (AREA)
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- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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| US3549697P | 1997-01-14 | 1997-01-14 | |
| US60/035,496 | 1997-01-14 | ||
| PCT/US1998/000153 WO1998030694A2 (en) | 1997-01-14 | 1998-01-13 | TUMOR NECROSIS FACTOR RECEPTORS 6α AND 6$g(b) |
Publications (1)
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| CA2277925A1 true CA2277925A1 (en) | 1998-07-16 |
Family
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| AT (1) | ATE365796T1 (cg-RX-API-DMAC7.html) |
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| US7888466B2 (en) | 1996-01-11 | 2011-02-15 | Human Genome Sciences, Inc. | Human G-protein chemokine receptor HSATU68 |
| US7357927B2 (en) | 1996-03-12 | 2008-04-15 | Human Genome Sciences, Inc. | Death domain containing receptors |
| US6713061B1 (en) | 1996-03-12 | 2004-03-30 | Human Genome Sciences, Inc. | Death domain containing receptors |
| WO1997033904A1 (en) | 1996-03-12 | 1997-09-18 | Human Genome Sciences, Inc. | Death domain containing receptors |
| US7964190B2 (en) | 1996-03-22 | 2011-06-21 | Human Genome Sciences, Inc. | Methods and compositions for decreasing T-cell activity |
| US6635743B1 (en) | 1996-03-22 | 2003-10-21 | Human Genome Sciences, Inc. | Apoptosis inducing molecule II and methods of use |
| US7285267B2 (en) | 1997-01-14 | 2007-10-23 | Human Genome Sciences, Inc. | Tumor necrosis factor receptors 6α & 6β |
| CN1247567A (zh) | 1997-01-14 | 2000-03-15 | 人体基因组科学有限公司 | 肿瘤坏死因子受体6α和6β |
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| AU9376498A (en) * | 1997-09-05 | 1999-03-22 | University Of Washington | Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents |
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| US6916907B1 (en) * | 1998-10-23 | 2005-07-12 | Curagen Corporation | Nucleic acids encoding osteoprotegern-like proteins and methods of using same |
| AU2164400A (en) * | 1998-12-09 | 2000-06-26 | Eli Lilly And Company | Flint compositions and uses thereof |
| WO2000037094A2 (en) * | 1998-12-22 | 2000-06-29 | Eli Lilly And Company | Therapeutic applications of flint polypeptides |
| WO2000046247A1 (en) * | 1999-02-05 | 2000-08-10 | Merck & Co., Inc. | Methods of use for dna molecules encoding m68, a tnf receptor-related protein |
| JP2002537769A (ja) | 1999-02-26 | 2002-11-12 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッド | ヒトエンドカインαおよび使用方法 |
| EP1159286A4 (en) * | 1999-03-04 | 2003-01-15 | Human Genome Sciences Inc | TUMOR NECROSIS FACTOR RECEPTORS 6 ALPHA AND 6 BETA |
| AU2495200A (en) * | 1999-03-08 | 2000-09-28 | Genentech Inc. | Compositions and methods for the treatment of tumor |
| US6835814B1 (en) | 1999-03-30 | 2004-12-28 | Eli Lilly And Company | Protease resistant flint analogs |
| AU3739500A (en) * | 1999-03-30 | 2000-10-16 | Eli Lilly And Company | Protease resistant flint analogs |
| US6965012B1 (en) * | 1999-03-30 | 2005-11-15 | Eli Lilly And Company | Flint polypeptide analogs |
| JP2002539828A (ja) * | 1999-03-30 | 2002-11-26 | イーライ・リリー・アンド・カンパニー | Ｆｌｉｎｔポリペプチドアナログ |
| US6627199B1 (en) | 1999-07-09 | 2003-09-30 | Amgen Inc | Isolation, identification and characterization of tmst2, a novel member of the TNF-receptor supergene family |
| WO2001010908A1 (en) * | 1999-08-04 | 2001-02-15 | Amgen Inc. | Ntr3, a member of the tnf-receptor supergene family |
| JP2003506088A (ja) | 1999-08-04 | 2003-02-18 | アムジェン インコーポレーテッド | ＴＮＦリガンドスーパー遺伝子ファミリーの新規のメンバーであるＦｈｍ |
| WO2001018055A1 (en) * | 1999-09-10 | 2001-03-15 | Eli Lilly And Company | Flint analog compounds and formulations thereof |
| WO2001018041A2 (en) * | 1999-09-10 | 2001-03-15 | Eli Lilly And Company | Flint proteins and formulations thereof |
| WO2001018202A2 (en) * | 1999-09-10 | 2001-03-15 | Eli Lilly And Company | Flint analog compounds and formulations thereof |
| WO2001096528A2 (en) | 2000-06-15 | 2001-12-20 | Human Genome Sciences, Inc. | Human tumor necrosis factor delta and epsilon |
| WO2002002641A1 (en) | 2000-06-16 | 2002-01-10 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to blys |
| CN1331125A (zh) * | 2000-06-26 | 2002-01-16 | 上海博德基因开发有限公司 | 一种新的多肽——人含细胞色素c结构域的tnfr/ngfr蛋白9.02和编码这种多肽的多核苷酸 |
| EP1322667A4 (en) * | 2000-08-25 | 2004-08-18 | Human Genome Sciences Inc | TUMOR NECROSIS FACTOR RECEPTORS 6-ALPHA AND 6-BETA |
| ES2437992T3 (es) | 2001-05-25 | 2014-01-15 | Human Genome Sciences, Inc. | Anticuerpos que se unen inmunoespecíficamente a los receptores de TRAIL |
| EP2261250B1 (en) | 2001-12-21 | 2015-07-01 | Human Genome Sciences, Inc. | GCSF-Albumin fusion proteins |
| JP5303092B2 (ja) | 2002-09-11 | 2013-10-02 | ジェネンテック， インコーポレイテッド | タンパク質精製 |
| JP5905184B2 (ja) | 2005-10-13 | 2016-04-20 | ヒューマン ジノーム サイエンシーズ， インコーポレイテッドＨｕｍａｎ Ｇｅｎｏｍｅ Ｓｃｉｅｎｃｅｓ， Ｉｎｃ． | 自己抗体陽性疾患を有する患者の処置に使用するための方法および組成物 |
| US20090269345A1 (en) * | 2005-12-23 | 2009-10-29 | Rong Fan | CLN248 Antibody Compositions and Methods of Use |
| US20110229471A1 (en) | 2008-11-26 | 2011-09-22 | Cedars-Sinai Medical Center | Methods of determining responsiveness to anti-tnf alpha therapy in inflammatory bowel disease |
| EP2406388B1 (en) * | 2009-03-13 | 2016-09-28 | The Trustees Of The University Of Pennsylvania | Ox40/trail fusion proteins |
| CN103874707B (zh) | 2010-11-19 | 2017-04-19 | 卫材R&D管理有限公司 | 中和抗‑ccl20抗体 |
| CA2908553A1 (en) | 2013-03-27 | 2014-10-02 | Cedars-Sinai Medical Center | Mitigation and reversal of fibrosis and inflammation by inhibition of tl1a function and related signaling pathways |
| CA2927309A1 (en) | 2013-05-24 | 2014-11-27 | Promis Neurosciences Inc. | Fasr antibodies for diagnostic and therapeutic use |
| EP4105236A1 (en) | 2013-07-19 | 2022-12-21 | Cedars-Sinai Medical Center | Anti-tl1a (tnfsf15) antibody for treatment of inflammatory bowel disease |
| JP7082945B2 (ja) | 2016-03-17 | 2022-06-09 | シーダーズ―シナイ メディカル センター | Ｒｎａｓｅｔ２により炎症性腸疾患を診断する方法 |
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| JPH09503672A (ja) | 1993-10-14 | 1997-04-15 | イミュネックス・コーポレーション | Ｆａｓ拮抗剤とその利用 |
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| WO2000037094A2 (en) | 1998-12-22 | 2000-06-29 | Eli Lilly And Company | Therapeutic applications of flint polypeptides |
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| EP1159286A4 (en) | 1999-03-04 | 2003-01-15 | Human Genome Sciences Inc | TUMOR NECROSIS FACTOR RECEPTORS 6 ALPHA AND 6 BETA |
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| US20040048254A1 (en) | 2000-03-15 | 2004-03-11 | Alexander Olek | Diagnosis of diseases associated with tumor supressor genes and oncogenes |
| WO2002000677A1 (en) | 2000-06-07 | 2002-01-03 | Human Genome Sciences, Inc. | Nucleic acids, proteins, and antibodies |
| EP1294947A2 (en) | 2000-06-30 | 2003-03-26 | Epigenomics AG | Method and nucleic acids for pharmacogenomic methylation analysis |
| WO2002009668A2 (en) | 2000-08-02 | 2002-02-07 | Eli Lilly And Company | Pulmonary administration of flint |
| US20030073144A1 (en) | 2001-01-30 | 2003-04-17 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of pancreatic cancer |
| AU2002246967A1 (en) | 2001-02-01 | 2002-08-12 | Eli Lilly And Company | Glycoforms a fas ligand inhibitory protein analog |
| US20040176279A1 (en) | 2001-02-01 | 2004-09-09 | Nigel Jenkins | Flint glycoforms |
| US20040236091A1 (en) | 2001-03-28 | 2004-11-25 | Chicz Roman M. | Translational profiling |
| FR2908832B1 (fr) | 2006-11-20 | 2011-08-26 | Valeo Systemes Thermiques | Carter pour echangeur de chaleur |
-
1998
- 1998-01-13 CN CN98801836A patent/CN1247567A/zh active Pending
- 1998-01-13 WO PCT/US1998/000153 patent/WO1998030694A2/en not_active Ceased
- 1998-01-13 ES ES98901699T patent/ES2286843T3/es not_active Expired - Lifetime
- 1998-01-13 DE DE69837996T patent/DE69837996T2/de not_active Expired - Fee Related
- 1998-01-13 CA CA002277925A patent/CA2277925A1/en not_active Abandoned
- 1998-01-13 US US09/006,352 patent/US8003386B1/en active Active
- 1998-01-13 BR BR9806954A patent/BR9806954A/pt not_active IP Right Cessation
- 1998-01-13 AU AU58157/98A patent/AU729062C/en not_active Ceased
- 1998-01-13 KR KR1019997006400A patent/KR20000070174A/ko not_active Ceased
- 1998-01-13 JP JP53103798A patent/JP2001507937A/ja not_active Withdrawn
- 1998-01-13 EP EP98901699A patent/EP1007659B1/en not_active Expired - Lifetime
- 1998-01-13 AT AT98901699T patent/ATE365796T1/de not_active IP Right Cessation
-
2000
- 2000-03-03 US US09/518,931 patent/US7186800B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US7186800B1 (en) | 2007-03-06 |
| WO1998030694A2 (en) | 1998-07-16 |
| EP1007659A2 (en) | 2000-06-14 |
| KR20000070174A (ko) | 2000-11-25 |
| DE69837996D1 (de) | 2007-08-09 |
| CN1247567A (zh) | 2000-03-15 |
| ATE365796T1 (de) | 2007-07-15 |
| AU5815798A (en) | 1998-08-03 |
| DE69837996T2 (de) | 2008-02-28 |
| BR9806954A (pt) | 2000-03-21 |
| US8003386B1 (en) | 2011-08-23 |
| JP2001507937A (ja) | 2001-06-19 |
| AU729062B2 (en) | 2001-01-25 |
| WO1998030694A3 (en) | 1998-11-12 |
| EP1007659B1 (en) | 2007-06-27 |
| AU729062C (en) | 2004-03-25 |
| ES2286843T3 (es) | 2007-12-01 |
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| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |