BR9806793A - Processos e composições de fator tissular para coagulação e tratamento de tumores. - Google Patents

Processos e composições de fator tissular para coagulação e tratamento de tumores.

Info

Publication number
BR9806793A
BR9806793A BR9806793-1A BR9806793A BR9806793A BR 9806793 A BR9806793 A BR 9806793A BR 9806793 A BR9806793 A BR 9806793A BR 9806793 A BR9806793 A BR 9806793A
Authority
BR
Brazil
Prior art keywords
compositions
tissue factor
coagulation
treatment
tumors
Prior art date
Application number
BR9806793-1A
Other languages
English (en)
Portuguese (pt)
Inventor
Philip E Thorpe
Steven W King
Boning Gao
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Texas filed Critical Univ Texas
Publication of BR9806793A publication Critical patent/BR9806793A/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6813Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6435Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a connective tissue peptide, e.g. collagen, fibronectin or gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827Proteins from mammals or birds
    • Y10S530/829Blood

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
BR9806793-1A 1997-01-22 1998-01-20 Processos e composições de fator tissular para coagulação e tratamento de tumores. BR9806793A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US3592097P 1997-01-22 1997-01-22
US3620597P 1997-01-27 1997-01-27
US4242797P 1997-03-27 1997-03-27
PCT/US1998/001012 WO1998031394A2 (en) 1997-01-22 1998-01-20 Tissue factor methods and compositions for coagulation and tumor treatment

Publications (1)

Publication Number Publication Date
BR9806793A true BR9806793A (pt) 2000-05-16

Family

ID=27364921

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9806793-1A BR9806793A (pt) 1997-01-22 1998-01-20 Processos e composições de fator tissular para coagulação e tratamento de tumores.

Country Status (17)

Country Link
US (5) US6132730A (cg-RX-API-DMAC7.html)
EP (1) EP0988056B1 (cg-RX-API-DMAC7.html)
JP (1) JP2002514201A (cg-RX-API-DMAC7.html)
KR (1) KR100565883B1 (cg-RX-API-DMAC7.html)
CN (1) CN100333796C (cg-RX-API-DMAC7.html)
AT (1) ATE244579T1 (cg-RX-API-DMAC7.html)
AU (1) AU735187C (cg-RX-API-DMAC7.html)
BR (1) BR9806793A (cg-RX-API-DMAC7.html)
CA (1) CA2278106C (cg-RX-API-DMAC7.html)
CY (1) CY2416B1 (cg-RX-API-DMAC7.html)
DE (1) DE69816297T9 (cg-RX-API-DMAC7.html)
ES (1) ES2197458T3 (cg-RX-API-DMAC7.html)
IL (1) IL130908A0 (cg-RX-API-DMAC7.html)
NO (1) NO323702B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ336720A (cg-RX-API-DMAC7.html)
PT (1) PT988056E (cg-RX-API-DMAC7.html)
WO (1) WO1998031394A2 (cg-RX-API-DMAC7.html)

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BR9806793A (pt) 1997-01-22 2000-05-16 Univ Texas Processos e composições de fator tissular para coagulação e tratamento de tumores.
US6303596B1 (en) 1997-05-22 2001-10-16 Oklahoma Medical Research Foundation Use of taurolidine for treatment of leukemias
US7740841B1 (en) 2000-01-28 2010-06-22 Sunnybrook Health Science Center Therapeutic method for reducing angiogenesis

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US7101557B2 (en) 2006-09-05
CY2416B1 (en) 2004-11-12
NO323702B1 (no) 2007-06-25
CA2278106C (en) 2005-04-12
NO993567L (no) 1999-09-21
DE69816297T9 (de) 2004-09-09
NZ336720A (en) 2001-06-29
US20030232753A1 (en) 2003-12-18
IL130908A0 (en) 2001-01-28
US7951356B1 (en) 2011-05-31
KR100565883B1 (ko) 2006-03-31
KR20000070389A (ko) 2000-11-25
CN1251532A (zh) 2000-04-26
US6132730A (en) 2000-10-17
AU5924398A (en) 1998-08-07
EP0988056A2 (en) 2000-03-29
PT988056E (pt) 2003-09-30
DE69816297D1 (de) 2003-08-14
CA2278106A1 (en) 1998-07-23
US6132729A (en) 2000-10-17
DE69816297T2 (de) 2003-12-24
EP0988056B1 (en) 2003-07-09
CN100333796C (zh) 2007-08-29
ATE244579T1 (de) 2003-07-15
NO993567D0 (no) 1999-07-21
WO1998031394A3 (en) 1998-09-17
ES2197458T3 (es) 2004-01-01
WO1998031394A2 (en) 1998-07-23
AU735187C (en) 2002-04-18
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AU735187B2 (en) 2001-07-05
US6156321A (en) 2000-12-05

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