KR100565883B1 - 응고 및 종양 치료용 조직 인자 방법 및 조성물 - Google Patents

응고 및 종양 치료용 조직 인자 방법 및 조성물 Download PDF

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KR100565883B1
KR100565883B1 KR1019997006622A KR19997006622A KR100565883B1 KR 100565883 B1 KR100565883 B1 KR 100565883B1 KR 1019997006622 A KR1019997006622 A KR 1019997006622A KR 19997006622 A KR19997006622 A KR 19997006622A KR 100565883 B1 KR100565883 B1 KR 100565883B1
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South Korea
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coagulation
tumor
tissue factor
composition
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Korean (ko)
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KR20000070389A (ko
Inventor
쏘프필립이
킹스티븐더블유
가오보닝
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보드 오브 리전츠, 더 유니버시티 오브 텍사스 시스템
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
    • A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
    • A61K47/6811—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin
    • A61K47/6813—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug being a protein or peptide, e.g. transferrin or bleomycin the drug being a peptidic cytokine, e.g. an interleukin or interferon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
    • A61K47/6435—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a connective tissue peptide, e.g. collagen, fibronectin or gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/829—Blood

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
KR1019997006622A 1997-01-22 1998-01-20 응고 및 종양 치료용 조직 인자 방법 및 조성물 Expired - Fee Related KR100565883B1 (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US3592097P 1997-01-22 1997-01-22
US3620597P 1997-01-27 1997-01-27
US4242797P 1997-03-27 1997-03-27
US60/035,920 1997-03-27
US60/042,427 1997-03-27
US60/036,205 1997-03-27
PCT/US1998/001012 WO1998031394A2 (en) 1997-01-22 1998-01-20 Tissue factor methods and compositions for coagulation and tumor treatment

Publications (2)

Publication Number Publication Date
KR20000070389A KR20000070389A (ko) 2000-11-25
KR100565883B1 true KR100565883B1 (ko) 2006-03-31

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KR1019997006622A Expired - Fee Related KR100565883B1 (ko) 1997-01-22 1998-01-20 응고 및 종양 치료용 조직 인자 방법 및 조성물

Country Status (17)

Country Link
US (5) US6132730A (cg-RX-API-DMAC7.html)
EP (1) EP0988056B1 (cg-RX-API-DMAC7.html)
JP (1) JP2002514201A (cg-RX-API-DMAC7.html)
KR (1) KR100565883B1 (cg-RX-API-DMAC7.html)
CN (1) CN100333796C (cg-RX-API-DMAC7.html)
AT (1) ATE244579T1 (cg-RX-API-DMAC7.html)
AU (1) AU735187C (cg-RX-API-DMAC7.html)
BR (1) BR9806793A (cg-RX-API-DMAC7.html)
CA (1) CA2278106C (cg-RX-API-DMAC7.html)
CY (1) CY2416B1 (cg-RX-API-DMAC7.html)
DE (1) DE69816297T9 (cg-RX-API-DMAC7.html)
ES (1) ES2197458T3 (cg-RX-API-DMAC7.html)
IL (1) IL130908A0 (cg-RX-API-DMAC7.html)
NO (1) NO323702B1 (cg-RX-API-DMAC7.html)
NZ (1) NZ336720A (cg-RX-API-DMAC7.html)
PT (1) PT988056E (cg-RX-API-DMAC7.html)
WO (1) WO1998031394A2 (cg-RX-API-DMAC7.html)

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US7101557B2 (en) 2006-09-05
CY2416B1 (en) 2004-11-12
NO323702B1 (no) 2007-06-25
CA2278106C (en) 2005-04-12
NO993567L (no) 1999-09-21
DE69816297T9 (de) 2004-09-09
NZ336720A (en) 2001-06-29
US20030232753A1 (en) 2003-12-18
IL130908A0 (en) 2001-01-28
US7951356B1 (en) 2011-05-31
KR20000070389A (ko) 2000-11-25
CN1251532A (zh) 2000-04-26
US6132730A (en) 2000-10-17
AU5924398A (en) 1998-08-07
EP0988056A2 (en) 2000-03-29
PT988056E (pt) 2003-09-30
DE69816297D1 (de) 2003-08-14
CA2278106A1 (en) 1998-07-23
US6132729A (en) 2000-10-17
DE69816297T2 (de) 2003-12-24
EP0988056B1 (en) 2003-07-09
CN100333796C (zh) 2007-08-29
ATE244579T1 (de) 2003-07-15
NO993567D0 (no) 1999-07-21
WO1998031394A3 (en) 1998-09-17
ES2197458T3 (es) 2004-01-01
WO1998031394A2 (en) 1998-07-23
AU735187C (en) 2002-04-18
JP2002514201A (ja) 2002-05-14
AU735187B2 (en) 2001-07-05
US6156321A (en) 2000-12-05

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