BR9804504B1 - isoquinolina-3-carboxamidas substituÍdas, processo para a preparaÇço das mesmas e medicamento. - Google Patents
isoquinolina-3-carboxamidas substituÍdas, processo para a preparaÇço das mesmas e medicamento.Info
- Publication number
- BR9804504B1 BR9804504B1 BRPI9804504-0A BR9804504A BR9804504B1 BR 9804504 B1 BR9804504 B1 BR 9804504B1 BR 9804504 A BR9804504 A BR 9804504A BR 9804504 B1 BR9804504 B1 BR 9804504B1
- Authority
- BR
- Brazil
- Prior art keywords
- carboxamides
- medicament
- preparation
- substituted isoquinoline
- isoquinoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19746287A DE19746287A1 (de) | 1997-10-20 | 1997-10-20 | Substituierte Isochinolin-2-Carbonsäureamide, ihre Herstellung und ihre Verwendung als Arzneimittel |
Publications (2)
Publication Number | Publication Date |
---|---|
BR9804504A BR9804504A (pt) | 2001-05-22 |
BR9804504B1 true BR9804504B1 (pt) | 2009-01-13 |
Family
ID=7846053
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI9804504-0A BR9804504B1 (pt) | 1997-10-20 | 1998-10-19 | isoquinolina-3-carboxamidas substituÍdas, processo para a preparaÇço das mesmas e medicamento. |
Country Status (25)
Country | Link |
---|---|
US (1) | US6093730A (pt) |
EP (2) | EP1538160B1 (pt) |
JP (2) | JP3782591B2 (pt) |
KR (1) | KR100618922B1 (pt) |
CN (1) | CN1117079C (pt) |
AR (1) | AR013696A1 (pt) |
AT (2) | ATE432940T1 (pt) |
AU (1) | AU755714B2 (pt) |
BR (1) | BR9804504B1 (pt) |
CA (2) | CA2250664A1 (pt) |
CZ (1) | CZ337298A3 (pt) |
DE (3) | DE19746287A1 (pt) |
DK (2) | DK0911340T3 (pt) |
ES (2) | ES2245471T3 (pt) |
HK (1) | HK1019605A1 (pt) |
HU (1) | HUP9802422A3 (pt) |
ID (1) | ID21115A (pt) |
IL (1) | IL126638A0 (pt) |
NO (1) | NO312365B1 (pt) |
NZ (1) | NZ332363A (pt) |
PL (1) | PL192354B1 (pt) |
PT (1) | PT911340E (pt) |
SG (1) | SG87776A1 (pt) |
TR (1) | TR199802106A2 (pt) |
ZA (1) | ZA989505B (pt) |
Families Citing this family (57)
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AU2001275014A1 (en) | 2000-05-30 | 2001-12-11 | Neurogen Corporation | Imidazoloisoquinolines |
US6762318B2 (en) * | 2001-12-03 | 2004-07-13 | Novo Nordisk A/S | Glucagon antagonists |
EP2324834B1 (en) * | 2001-12-06 | 2019-05-08 | Fibrogen, Inc. | Methods of Increasing Endogenous Erythropoietin (EPO) |
EP2295060B1 (en) | 2001-12-06 | 2018-10-31 | Fibrogen, Inc. | Treatment or prevention of ischemic or hypoxic conditions |
US8318703B2 (en) | 2001-12-06 | 2012-11-27 | Fibrogen, Inc. | Methods for improving kidney function |
US8124582B2 (en) * | 2002-12-06 | 2012-02-28 | Fibrogen, Inc. | Treatment of diabetes |
US7618940B2 (en) * | 2002-12-06 | 2009-11-17 | Fibrogen, Inc. | Fat regulation |
SI1644336T1 (sl) | 2003-06-06 | 2011-06-30 | Fibrogen Inc | Heteroarilne spojine, ki vsebujejo duĺ ik in njihova uporaba pri zviĺ anju endogenega eritropoetina |
US20060251638A1 (en) * | 2003-06-06 | 2006-11-09 | Volkmar Guenzler-Pukall | Cytoprotection through the use of hif hydroxylase inhibitors |
US8614204B2 (en) * | 2003-06-06 | 2013-12-24 | Fibrogen, Inc. | Enhanced erythropoiesis and iron metabolism |
EP1893186A2 (en) * | 2005-06-06 | 2008-03-05 | Fibrogen, Inc. | Improved treatment for anemia using a hif-alpha stabilising agent |
ATE470439T1 (de) | 2005-06-15 | 2010-06-15 | Fibrogen Inc | Verwendung von hif 1alfa modulatoren zur behandlung von krebs |
US7728130B2 (en) | 2005-12-09 | 2010-06-01 | Amgen Inc. | Quinolone based compounds exhibiting prolyl hydroxylase inhibitory activity |
WO2007090068A2 (en) | 2006-01-27 | 2007-08-09 | Fibrogen, Inc. | Cyanoisoquinoline compounds that stabilize hypoxia inducible factor (hif) |
WO2007101204A1 (en) * | 2006-02-27 | 2007-09-07 | Alcon Research, Ltd. | Method of treating glaucoma |
US7745461B1 (en) | 2006-02-27 | 2010-06-29 | Alcon Research, Ltd. | Method of treating dry eye disorders |
KR100949982B1 (ko) * | 2006-03-30 | 2010-03-29 | 엘지전자 주식회사 | 비디오 신호를 디코딩/인코딩하기 위한 방법 및 장치 |
BRPI0710527B8 (pt) | 2006-04-04 | 2021-05-25 | Fibrogen Inc | compostos de pirrolo- e tiazolo-piridina e composição farmacêutica que os compreende |
CA2659682C (en) | 2006-06-26 | 2010-12-21 | The Procter & Gamble Company | Prolyl hydroxylase inhibitors and methods of use |
US7635715B2 (en) | 2006-12-18 | 2009-12-22 | Amgen Inc. | Naphthalenone compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof |
US8048892B2 (en) | 2006-12-18 | 2011-11-01 | Amgen Inc. | Azaquinolone based compounds exhibiting prolyl hydroxylase inhibitory activity, compositions, and uses thereof |
WO2008130600A2 (en) | 2007-04-18 | 2008-10-30 | Amgen Inc. | Quinolones and azaquinolones that inhibit prolyl hydroxylase |
WO2008130508A1 (en) | 2007-04-18 | 2008-10-30 | Amgen Inc. | Indanone derivatives that inhibit prolyl hydroxylase |
WO2008137060A1 (en) | 2007-05-04 | 2008-11-13 | Amgen Inc. | Thienopyridine and thiazolopyridine derivatives that inhibit prolyl hydroxylase activity |
CA2685219C (en) | 2007-05-04 | 2012-06-19 | Amgen Inc. | Diazaquinolones that inhibit prolyl hydroxylase activity |
WO2009002533A1 (en) * | 2007-06-27 | 2008-12-31 | The Brigham And Women's Hospital, Inc. | Inflammatory bowel disease therapies |
CN101497584B (zh) * | 2008-01-29 | 2010-12-22 | 首都医科大学 | 异喹啉-3-甲酰氨基酸苄酯及其制备和应用 |
DK2294066T3 (da) | 2008-04-28 | 2014-09-08 | Janssen Pharmaceutica Nv | Benzoimidazoler som prolylhydroxylaseinhibitorer |
CN105037323A (zh) | 2008-11-14 | 2015-11-11 | 菲布罗根有限公司 | 作为hif羟化酶抑制剂的苯并噻喃衍生物 |
KR101706803B1 (ko) | 2009-07-17 | 2017-02-14 | 니뽄 다바코 산교 가부시키가이샤 | 트리아졸로피리딘 화합물, 그리고 그 프롤릴 수산화효소 저해제 및 에리트로포이에틴 생성 유도제로서의 작용 |
NO2686520T3 (pt) | 2011-06-06 | 2018-03-17 | ||
CN104024227B (zh) * | 2011-07-22 | 2015-12-02 | 北京贝美拓新药研发有限公司 | 抑制脯氨酸羟化酶活性的化合物的晶型及其应用 |
IN2014DN03155A (pt) | 2011-10-25 | 2015-05-22 | Janssen Pharmaceutica Nv | |
WO2013134660A1 (en) | 2012-03-09 | 2013-09-12 | Fibrogen, Inc. | 4 -hydroxy- isoquinoline compounds as hif hydroxylase inhibitors |
MX350922B (es) | 2012-07-16 | 2017-09-25 | Fibrogen Inc | Proceso para elaborar compuestos de isoquinolina. |
US8883823B2 (en) | 2012-07-16 | 2014-11-11 | Fibrogen, Inc. | Crystalline forms of a prolyl hydroxylase inhibitor |
PT2872488T (pt) | 2012-07-16 | 2018-11-22 | Fibrogen Inc | Formas cristalinas do ácido [(4-hidroxi-1-metil-7-fenoxi-isoquinolina-3-carbonil)amino]acético inibidor da prolil-hidroxilase |
WO2014070859A1 (en) * | 2012-10-30 | 2014-05-08 | H. Lee Moffitt Cancer Center And Research Institute, Inc. | Stat3 dimerization inhibitors |
AU2014209319B2 (en) | 2013-01-24 | 2018-04-19 | Fibrogen, Inc. | Crystalline forms of {[1-cyano-5-(4-chlorophenoxy)-4-hydroxy-isoquinoline-3-carbonyl]-amino}-acetic acid |
WO2014197660A1 (en) | 2013-06-06 | 2014-12-11 | Fibrogen, Inc. | Pharmaceutical formulations of a hif hydroxylase inhibitor |
PT3007695T (pt) | 2013-06-13 | 2024-03-07 | Akebia Therapeutics Inc | Composições e métodos para tratamento de anemia |
PE20160945A1 (es) | 2013-11-15 | 2016-09-26 | Akebia Therapeutics Inc | Formas solidas de acido {[5-(3-clorofenil)-3-hidroxipiridin-2-carbonil]amino}acetico, composiciones, y usos de las mismas |
US10238675B2 (en) | 2014-05-15 | 2019-03-26 | Insmed Incorporated | Methods for treating pulmonary non-tuberculous mycobacterial infections |
CA2974691A1 (en) | 2015-01-23 | 2016-07-28 | Akebia Therapeutics, Inc. | Solid forms of 2-(5-(3-fluorophenyl)-3-hydroxypicolinamido)acetic acid, compositions, and uses thereof |
IL292262B2 (en) | 2015-04-01 | 2024-02-01 | Akebia Therapeutics Inc | Formulation of an oral administration form of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino}acetic acid |
KR102473897B1 (ko) * | 2015-05-28 | 2022-12-06 | 니뽄 다바코 산교 가부시키가이샤 | 당뇨병성 신증을 치료 또는 예방하는 방법 |
US20180200186A1 (en) * | 2015-07-09 | 2018-07-19 | Insmed Incorporated | Compositions and methods for treating lung diseases and lung injury |
AR108325A1 (es) | 2016-04-27 | 2018-08-08 | Samumed Llc | Isoquinolin-3-il carboxamidas y preparación y uso de las mismas |
AR108326A1 (es) | 2016-04-27 | 2018-08-08 | Samumed Llc | Isoquinolin-3-il carboxamidas y preparación y uso de las mismas |
KR20200112872A (ko) * | 2018-01-09 | 2020-10-05 | 코넬 유니버시티 | 장기 섬유증의 예방 및 치료 |
WO2019191627A1 (en) | 2018-03-30 | 2019-10-03 | Insmed Incorporated | Methods for continuous manufacture of liposomal drug products |
AU2019265629A1 (en) | 2018-05-09 | 2021-01-07 | Akebia Therapeutics, Inc. | Process for preparing 2-((5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl)amino)acetic acid |
WO2020028745A1 (en) * | 2018-08-03 | 2020-02-06 | Cornell University | Methods for reducing abnormal scar formation |
TW202120490A (zh) | 2019-07-30 | 2021-06-01 | 德商拜耳動物保健有限公司 | 新穎異喹啉衍生物 |
US11524939B2 (en) | 2019-11-13 | 2022-12-13 | Akebia Therapeutics, Inc. | Solid forms of {[5-(3-chlorophenyl)-3-hydroxypyridine-2-carbonyl]amino} acetic acid |
CN112979541B (zh) * | 2019-12-17 | 2022-11-11 | 浙江大学 | 一种基于n-(3-羟基吡啶-2-羰基)甘氨酸的抗肿瘤药物增敏剂及其应用 |
CN116120340B (zh) * | 2021-11-15 | 2023-10-31 | 艾立康药业股份有限公司 | 一种吡啶并噁嗪类化合物及其制备方法、组合物和用途 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4015255A1 (de) * | 1990-05-12 | 1991-11-14 | Hoechst Ag | Oxalyl-aminosaeurederivate, verfahren zu ihrer herstellung und ihrer verwendung als arzneimittel zur inhibierung der prolyl-hydroxylase |
CA2085954A1 (en) * | 1991-12-24 | 1993-06-25 | Klaus Weidmann | Substituted pyridine n-oxides, processes for their preparation, and their use |
TW352384B (en) * | 1992-03-24 | 1999-02-11 | Hoechst Ag | Sulfonamido- or sulfonamidocarbonylpyridine-2-carboxamides, process for their preparation and their use as pharmaceuticals |
DE4233124A1 (de) * | 1992-10-02 | 1994-04-07 | Hoechst Ag | Acylsulfonamido- und Sulfonamidopyridin-2-carbonsäureester sowie ihre Pyridin-N-oxide, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel |
EP0650961B1 (de) * | 1993-11-02 | 1997-03-05 | Hoechst Aktiengesellschaft | Substituierte heterocyclische Carbonsäureamide, ihre Herstellung und ihre Verwendung als Arzneimittel |
DK0650960T3 (da) * | 1993-11-02 | 1997-09-01 | Hoechst Ag | Substituerede heterocykliske carboxylsyreamid-estere, deres fremstilling og deres anvendelse som lægemidler. |
CA2138929A1 (en) * | 1993-12-30 | 1995-07-01 | Klaus Weidmann | Substituted heterocyclic carboxamides, their preparation and their use as pharmaceuticals |
SE9400810D0 (sv) * | 1994-03-10 | 1994-03-10 | Pharmacia Ab | New use of Quinoline-3-carboxamide compounds |
IL135495A (en) * | 1995-09-28 | 2002-12-01 | Hoechst Ag | Intermediate compounds for the preparation of quinoline-converted amines - 2 - carboxylic acid |
-
1997
- 1997-10-20 DE DE19746287A patent/DE19746287A1/de not_active Withdrawn
-
1998
- 1998-10-16 ES ES98119591T patent/ES2245471T3/es not_active Expired - Lifetime
- 1998-10-16 AT AT05004047T patent/ATE432940T1/de active
- 1998-10-16 NZ NZ332363A patent/NZ332363A/xx unknown
- 1998-10-16 DE DE59814365T patent/DE59814365D1/de not_active Expired - Lifetime
- 1998-10-16 DE DE59812907T patent/DE59812907D1/de not_active Expired - Lifetime
- 1998-10-16 EP EP05004047A patent/EP1538160B1/de not_active Expired - Lifetime
- 1998-10-16 ES ES05004047T patent/ES2328156T3/es not_active Expired - Lifetime
- 1998-10-16 AT AT98119591T patent/ATE299148T1/de active
- 1998-10-16 ID IDP981374A patent/ID21115A/id unknown
- 1998-10-16 DK DK98119591T patent/DK0911340T3/da active
- 1998-10-16 PT PT98119591T patent/PT911340E/pt unknown
- 1998-10-16 AR ARP980105164A patent/AR013696A1/es unknown
- 1998-10-16 EP EP98119591A patent/EP0911340B1/de not_active Expired - Lifetime
- 1998-10-16 DK DK05004047T patent/DK1538160T3/da active
- 1998-10-18 IL IL12663898A patent/IL126638A0/xx unknown
- 1998-10-19 CZ CZ983372A patent/CZ337298A3/cs unknown
- 1998-10-19 HU HU9802422A patent/HUP9802422A3/hu unknown
- 1998-10-19 JP JP29701198A patent/JP3782591B2/ja not_active Expired - Lifetime
- 1998-10-19 US US09/174,558 patent/US6093730A/en not_active Expired - Lifetime
- 1998-10-19 NO NO19984877A patent/NO312365B1/no not_active IP Right Cessation
- 1998-10-19 CA CA002250664A patent/CA2250664A1/en not_active Abandoned
- 1998-10-19 ZA ZA989505A patent/ZA989505B/xx unknown
- 1998-10-19 KR KR1019980043578A patent/KR100618922B1/ko active IP Right Grant
- 1998-10-19 TR TR1998/02106A patent/TR199802106A2/xx unknown
- 1998-10-19 BR BRPI9804504-0A patent/BR9804504B1/pt not_active IP Right Cessation
- 1998-10-19 AU AU89413/98A patent/AU755714B2/en not_active Expired
- 1998-10-20 PL PL329274A patent/PL192354B1/pl unknown
- 1998-10-20 CA CA2251647A patent/CA2251647C/en not_active Expired - Lifetime
- 1998-10-20 CN CN98121000A patent/CN1117079C/zh not_active Expired - Lifetime
- 1998-10-20 SG SG9804225A patent/SG87776A1/en unknown
-
1999
- 1999-10-27 HK HK99104801A patent/HK1019605A1/xx not_active IP Right Cessation
-
2005
- 2005-09-02 JP JP2005254578A patent/JP4691419B2/ja not_active Expired - Lifetime
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