BR9714498A - composição farmacêutica, e, associação de um produto. - Google Patents
composição farmacêutica, e, associação de um produto.Info
- Publication number
- BR9714498A BR9714498A BR9714498A BR9714498A BR9714498A BR 9714498 A BR9714498 A BR 9714498A BR 9714498 A BR9714498 A BR 9714498A BR 9714498 A BR9714498 A BR 9714498A BR 9714498 A BR9714498 A BR 9714498A
- Authority
- BR
- Brazil
- Prior art keywords
- alkyl
- hydrogen
- formula
- alkylthio
- optionally substituted
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/58—[b]- or [c]-condensed
- C07D209/72—4,7-Endo-alkylene-iso-indoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Epoxy Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9616206A FR2757855B1 (fr) | 1996-12-30 | 1996-12-30 | Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent |
| PCT/FR1997/002407 WO1998029390A1 (fr) | 1996-12-30 | 1997-12-23 | Inhibiteurs de farnesyle transferase |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR9714498A true BR9714498A (pt) | 2000-03-21 |
Family
ID=9499293
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR9714498A BR9714498A (pt) | 1996-12-30 | 1997-12-23 | composição farmacêutica, e, associação de um produto. |
Country Status (32)
| Country | Link |
|---|---|
| EP (1) | EP0948483B1 (en:Method) |
| JP (1) | JP2001509147A (en:Method) |
| KR (1) | KR20000062391A (en:Method) |
| AR (1) | AR008950A1 (en:Method) |
| AT (1) | ATE214367T1 (en:Method) |
| AU (1) | AU741921B2 (en:Method) |
| BR (1) | BR9714498A (en:Method) |
| CA (1) | CA2275943A1 (en:Method) |
| CO (1) | CO4920252A1 (en:Method) |
| CZ (1) | CZ233599A3 (en:Method) |
| DE (1) | DE69711081T2 (en:Method) |
| DK (1) | DK0948483T3 (en:Method) |
| DZ (1) | DZ2389A1 (en:Method) |
| EA (1) | EA002114B1 (en:Method) |
| ES (1) | ES2172033T3 (en:Method) |
| FR (1) | FR2757855B1 (en:Method) |
| HU (1) | HUP0001747A3 (en:Method) |
| ID (1) | ID22922A (en:Method) |
| IL (1) | IL130453A0 (en:Method) |
| MA (1) | MA26460A1 (en:Method) |
| NO (1) | NO993225L (en:Method) |
| NZ (1) | NZ336042A (en:Method) |
| PE (1) | PE28199A1 (en:Method) |
| PL (1) | PL334345A1 (en:Method) |
| PT (1) | PT948483E (en:Method) |
| SK (1) | SK88399A3 (en:Method) |
| TN (1) | TNSN97214A1 (en:Method) |
| TR (1) | TR199901502T2 (en:Method) |
| UY (1) | UY24832A1 (en:Method) |
| WO (1) | WO1998029390A1 (en:Method) |
| YU (1) | YU30299A (en:Method) |
| ZA (1) | ZA9711734B (en:Method) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2787327B1 (fr) * | 1998-12-21 | 2003-01-17 | Aventis Pharma Sa | Compositions contenant des inhibiteurs de farnesyle transferase |
| FR2796640A1 (fr) * | 1999-07-22 | 2001-01-26 | Aventis Pharma Sa | Nouveaux inhibiteurs de farnesyle transferase, leur preparation, les compositions pharmaceutiques qui les contiennent et leur utilisation pour la preparation de medicaments |
| FR2796641B1 (fr) * | 1999-07-22 | 2001-09-21 | Aventis Pharma Sa | Nouveau procede de preparation de composes benzoperhydroisoindole |
| FR2845994B1 (fr) * | 2002-10-18 | 2006-05-19 | Servier Lab | Nouveaux derives de benzo[e][1,4]oxazino[3,2-g]isoindole substitues, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| CA2559221A1 (en) * | 2004-03-18 | 2005-09-29 | Brigham And Women's Hospital, Inc. | Methods for the treatment of synucleinopathies |
| WO2024229406A1 (en) | 2023-05-04 | 2024-11-07 | Revolution Medicines, Inc. | Combination therapy for a ras related disease or disorder |
| US20250154171A1 (en) | 2023-10-12 | 2025-05-15 | Revolution Medicines, Inc. | Ras inhibitors |
| WO2025171296A1 (en) | 2024-02-09 | 2025-08-14 | Revolution Medicines, Inc. | Ras inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3597863B2 (ja) * | 1993-11-05 | 2004-12-08 | ワーナー−ランバート・コンパニー | タンパク質：ファルネシルトランスフェラーゼの置換されたジ‐およびトリペプチド阻害剤 |
| FR2736641B1 (fr) * | 1995-07-10 | 1997-08-22 | Rhone Poulenc Rorer Sa | Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent |
-
1996
- 1996-12-30 FR FR9616206A patent/FR2757855B1/fr not_active Expired - Fee Related
-
1997
- 1997-12-03 PE PE1997001089A patent/PE28199A1/es not_active Application Discontinuation
- 1997-12-23 WO PCT/FR1997/002407 patent/WO1998029390A1/fr not_active Application Discontinuation
- 1997-12-23 CA CA002275943A patent/CA2275943A1/fr not_active Abandoned
- 1997-12-23 PT PT97953000T patent/PT948483E/pt unknown
- 1997-12-23 JP JP52968698A patent/JP2001509147A/ja not_active Ceased
- 1997-12-23 AU AU56694/98A patent/AU741921B2/en not_active Ceased
- 1997-12-23 PL PL97334345A patent/PL334345A1/xx unknown
- 1997-12-23 EP EP97953000A patent/EP0948483B1/fr not_active Expired - Lifetime
- 1997-12-23 KR KR1019997005966A patent/KR20000062391A/ko not_active Ceased
- 1997-12-23 BR BR9714498A patent/BR9714498A/pt not_active IP Right Cessation
- 1997-12-23 EA EA199900608A patent/EA002114B1/ru not_active IP Right Cessation
- 1997-12-23 NZ NZ336042A patent/NZ336042A/xx unknown
- 1997-12-23 SK SK883-99A patent/SK88399A3/sk unknown
- 1997-12-23 HU HU0001747A patent/HUP0001747A3/hu unknown
- 1997-12-23 DE DE69711081T patent/DE69711081T2/de not_active Expired - Fee Related
- 1997-12-23 DK DK97953000T patent/DK0948483T3/da active
- 1997-12-23 ID IDW990618A patent/ID22922A/id unknown
- 1997-12-23 YU YU30299A patent/YU30299A/sh unknown
- 1997-12-23 CZ CZ992335A patent/CZ233599A3/cs unknown
- 1997-12-23 IL IL13045397A patent/IL130453A0/xx unknown
- 1997-12-23 AT AT97953000T patent/ATE214367T1/de not_active IP Right Cessation
- 1997-12-23 TR TR1999/01502T patent/TR199901502T2/xx unknown
- 1997-12-23 ES ES97953000T patent/ES2172033T3/es not_active Expired - Lifetime
- 1997-12-26 MA MA24915A patent/MA26460A1/fr unknown
- 1997-12-26 TN TNTNSN97214A patent/TNSN97214A1/fr unknown
- 1997-12-27 DZ DZ970239A patent/DZ2389A1/xx active
- 1997-12-29 CO CO97075391A patent/CO4920252A1/es unknown
- 1997-12-30 ZA ZA9711734A patent/ZA9711734B/xx unknown
- 1997-12-30 AR ARP970106263A patent/AR008950A1/es unknown
- 1997-12-30 UY UY24832A patent/UY24832A1/es not_active Application Discontinuation
-
1999
- 1999-06-29 NO NO993225A patent/NO993225L/no not_active Application Discontinuation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A E 8A ANUIDADES. |
|
| B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1861 DE 05/09/2006. |