BR9714299A - Composto macromolecular, processos para detecção de virus da influenza e tratamento de infeção da influenza, composição farmacêutica para esse tratamento e utilização de composto - Google Patents
Composto macromolecular, processos para detecção de virus da influenza e tratamento de infeção da influenza, composição farmacêutica para esse tratamento e utilização de compostoInfo
- Publication number
- BR9714299A BR9714299A BR9714299-9A BR9714299A BR9714299A BR 9714299 A BR9714299 A BR 9714299A BR 9714299 A BR9714299 A BR 9714299A BR 9714299 A BR9714299 A BR 9714299A
- Authority
- BR
- Brazil
- Prior art keywords
- treatment
- compound
- processes
- influenza
- detection
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
- C08B37/0009—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Glucans, e.g. polydextrose, alternan, glycogen; (alpha-1,4)(alpha-1,6)-D-Glucans; (alpha-1,3)(alpha-1,4)-D-Glucans, e.g. isolichenan or nigeran; (alpha-1,4)-D-Glucans; (alpha-1,3)-D-Glucans, e.g. pseudonigeran; Derivatives thereof
- C08B37/0021—Dextran, i.e. (alpha-1,4)-D-glucan; Derivatives thereof, e.g. Sephadex, i.e. crosslinked dextran
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08F—MACROMOLECULAR COMPOUNDS OBTAINED BY REACTIONS ONLY INVOLVING CARBON-TO-CARBON UNSATURATED BONDS
- C08F8/00—Chemical modification by after-treatment
- C08F8/30—Introducing nitrogen atoms or nitrogen-containing groups
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
- G01N2333/08—RNA viruses
- G01N2333/11—Orthomyxoviridae, e.g. influenza virus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
- G01N2333/924—Hydrolases (3) acting on glycosyl compounds (3.2)
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Polymers & Plastics (AREA)
- Urology & Nephrology (AREA)
- General Chemical & Material Sciences (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Food Science & Technology (AREA)
- Materials Engineering (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Abstract
<B><MU>COMPOSTO MACROMOLECULAR, PROCESSOS PARA DETECçãO DE VìRUS DA INFLUENZA E TRATAMENTO DE INFECçãO DA INFLUENZA, COMPOSIçãO FARMACêUTICA PARA ESSE TRATAMENTO E UTILIZAçãO DE COMPOSTO<MV><D>. A invenção proporciona novas macromoléculas, processos para a sua preparação, suas formulações farmacêuticas e sua utilização como agentes contra influenza. A invenção também propociona um novo processo de diagnóstico que pode ser usado para detecção de todos os tipos de vírus de influenza A e B. O composto macromolecular da invenção tem fixadas a ele uma ou mais moléculas (aglutinantes de neuraminidase) que se ligam ao local de neuraminidase de vírus da influenza ativo, mas que não são divididos pela neuraminidase.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPO3632A AUPO363296A0 (en) | 1996-11-14 | 1996-11-14 | Method and novel compounds for use therein |
AUPO8539A AUPO853997A0 (en) | 1997-08-14 | 1997-08-14 | Method and novel compounds for use therein |
PCT/AU1997/000771 WO1998021243A1 (en) | 1996-11-14 | 1997-11-13 | Method and novel compounds for use therein |
Publications (1)
Publication Number | Publication Date |
---|---|
BR9714299A true BR9714299A (pt) | 2000-04-25 |
Family
ID=25645315
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR9714299-9A BR9714299A (pt) | 1996-11-14 | 1997-11-13 | Composto macromolecular, processos para detecção de virus da influenza e tratamento de infeção da influenza, composição farmacêutica para esse tratamento e utilização de composto |
Country Status (19)
Country | Link |
---|---|
US (1) | US6680054B1 (pt) |
EP (1) | EP0951480A4 (pt) |
JP (1) | JP3691075B2 (pt) |
KR (1) | KR20000068986A (pt) |
CN (1) | CN1238783A (pt) |
AP (1) | AP9901531A0 (pt) |
AU (1) | AU732916C (pt) |
BR (1) | BR9714299A (pt) |
CA (1) | CA2271249C (pt) |
CZ (1) | CZ167999A3 (pt) |
EA (1) | EA001603B1 (pt) |
HU (1) | HUP9904009A3 (pt) |
IL (1) | IL129762A0 (pt) |
IS (1) | IS5044A (pt) |
NO (1) | NO992297L (pt) |
NZ (1) | NZ335368A (pt) |
PL (1) | PL333364A1 (pt) |
TR (1) | TR199901081T2 (pt) |
WO (1) | WO1998021243A1 (pt) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6455571B1 (en) | 1998-04-23 | 2002-09-24 | Abbott Laboratories | Inhibitors of neuraminidases |
US6518305B1 (en) | 1998-04-23 | 2003-02-11 | Abbott Laboratories | Five-membered carbocyclic and heterocyclic inhibitors of neuraminidases |
US7425541B2 (en) * | 1998-12-11 | 2008-09-16 | Medarex, Inc. | Enzyme-cleavable prodrug compounds |
AUPP913999A0 (en) | 1999-03-12 | 1999-04-01 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
US6593314B1 (en) | 1999-10-19 | 2003-07-15 | Abbott Laboratories | Neuraminidase inhibitors |
GB0015324D0 (en) * | 2000-06-22 | 2000-08-16 | Biota Scient Management | Medicaments |
AUPR001000A0 (en) * | 2000-09-08 | 2000-10-05 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
US20030068655A1 (en) * | 2001-09-12 | 2003-04-10 | Protiveris, Inc. | Microcantilever apparatus and methods for detection of enzymes |
AUPR879401A0 (en) | 2001-11-09 | 2001-12-06 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
EP1853634B1 (en) * | 2005-02-23 | 2016-08-10 | Lipoxen Technologies Limited | Activated sialic acid derivatives for protein derivatisation and conjugation |
US7960139B2 (en) | 2007-03-23 | 2011-06-14 | Academia Sinica | Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells |
EA017957B1 (ru) * | 2007-06-25 | 2013-04-30 | Дзе Администрейторс Оф Дзе Тьюлейн Эдьюкейшнл Фанд | Композиции и способы, ингибирующие грипп |
AU2008272854B2 (en) * | 2007-07-03 | 2014-03-13 | Children's Hospital & Research Center At Oakland | Inhibitors of polysialic acid de-N-acetylase and methods for using the same |
JP5523313B2 (ja) | 2007-07-03 | 2014-06-18 | チルドレンズ ホスピタル アンド リサーチ センター アット オークランド | ポリシアル酸誘導体、製造方法、ならびにがん抗原産生の増強およびターゲティングにおける使用 |
JP5702600B2 (ja) | 2007-07-03 | 2015-04-15 | チルドレンズ ホスピタル アンド リサーチ センター アット オークランド | オリゴシアル酸誘導体、製造方法および免疫学的使用 |
US20130280204A1 (en) * | 2007-08-27 | 2013-10-24 | Massachusetts Institute Of Technology | Polymer-Attached Inhibitors of Influenza Virus |
US20090076133A1 (en) * | 2007-09-14 | 2009-03-19 | Protia, Llc | Deuterium-enriched zanamivir |
US8680020B2 (en) | 2008-07-15 | 2014-03-25 | Academia Sinica | Glycan arrays on PTFE-like aluminum coated glass slides and related methods |
AU2010247141A1 (en) | 2009-05-15 | 2011-12-15 | Redx Pharma Plc | Redox drug derivatives |
US11377485B2 (en) | 2009-12-02 | 2022-07-05 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
US10087236B2 (en) | 2009-12-02 | 2018-10-02 | Academia Sinica | Methods for modifying human antibodies by glycan engineering |
WO2011130332A1 (en) | 2010-04-12 | 2011-10-20 | Academia Sinica | Glycan arrays for high throughput screening of viruses |
US10130714B2 (en) | 2012-04-14 | 2018-11-20 | Academia Sinica | Enhanced anti-influenza agents conjugated with anti-inflammatory activity |
PL225045B1 (pl) | 2012-05-18 | 2017-02-28 | Univ Jagielloński | Zastosowanie polimeru chitozanowego do wytwarzania leków do leczenia i profilaktyki infekcji wywołanych przez koronawirusy |
AU2013306098A1 (en) | 2012-08-18 | 2015-02-12 | Academia Sinica | Cell-permeable probes for identification and imaging of sialidases |
WO2014152946A2 (en) | 2013-03-14 | 2014-09-25 | University Of Washington Through Its Center For Commercialization | Polypeptides for treating and/or limiting influenza infection |
CN105264086B (zh) | 2013-04-01 | 2018-06-15 | 贝克顿·迪金森公司 | 用于流感诊断的方法和试剂盒 |
US10086054B2 (en) | 2013-06-26 | 2018-10-02 | Academia Sinica | RM2 antigens and use thereof |
US9981030B2 (en) | 2013-06-27 | 2018-05-29 | Academia Sinica | Glycan conjugates and use thereof |
EP3041484B1 (en) | 2013-09-06 | 2021-03-03 | Academia Sinica | Human inkt cell activation using glycolipids with altered glycosyl groups |
AU2015206370A1 (en) | 2014-01-16 | 2016-07-07 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
US10150818B2 (en) | 2014-01-16 | 2018-12-11 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
TWI687428B (zh) | 2014-03-27 | 2020-03-11 | 中央研究院 | 反應性標記化合物及其用途 |
KR102576850B1 (ko) | 2014-05-27 | 2023-09-11 | 아카데미아 시니카 | 박테로이드 기원의 푸코시다제 및 이의 사용 방법 |
US10118969B2 (en) | 2014-05-27 | 2018-11-06 | Academia Sinica | Compositions and methods relating to universal glycoforms for enhanced antibody efficacy |
US10005847B2 (en) | 2014-05-27 | 2018-06-26 | Academia Sinica | Anti-HER2 glycoantibodies and uses thereof |
KR20170003720A (ko) | 2014-05-27 | 2017-01-09 | 아카데미아 시니카 | 항-cd20 글리코항체 및 이의 용도 |
CA2950433A1 (en) | 2014-05-28 | 2015-12-03 | Academia Sinica | Anti-tnf-alpha glycoantibodies and uses thereof |
JP6899321B2 (ja) | 2014-09-08 | 2021-07-07 | アカデミア シニカAcademia Sinica | 糖脂質を使用するヒトiNKT細胞活性化 |
US9975965B2 (en) | 2015-01-16 | 2018-05-22 | Academia Sinica | Compositions and methods for treatment and detection of cancers |
US10495645B2 (en) | 2015-01-16 | 2019-12-03 | Academia Sinica | Cancer markers and methods of use thereof |
AU2015378564A1 (en) | 2015-01-24 | 2017-07-13 | Academia Sinica | Novel glycan conjugates and methods of use thereof |
CA3005774C (en) | 2015-11-20 | 2024-01-09 | Australian Biomedical Co. Pty Ltd | Compounds and methods for the treatment and/or prevention of influenza infection |
TW201808978A (zh) | 2016-03-08 | 2018-03-16 | 中央研究院 | N-聚醣及其陣列之模組化合成方法 |
CN109963868B (zh) | 2016-08-22 | 2023-11-14 | 醣基生医股份有限公司 | 抗体、结合片段及使用方法 |
JP2021536483A (ja) | 2018-09-06 | 2021-12-27 | シダラ セラピューティクス インコーポレーテッド | ウイルス感染症の治療のための組成物及び方法 |
TW202122117A (zh) | 2019-09-06 | 2021-06-16 | 美商席達拉醫療有限公司 | 用於治療病毒感染之組合物及方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ288492B6 (en) | 1990-04-24 | 2001-06-13 | Biota Scient Management | Derivatives of alpha-D-neuraminic acid, process of their preparation, their use and pharmaceutical preparations based thereon |
US5221611A (en) | 1991-06-19 | 1993-06-22 | Sigma Chemical Company | Ddi immunoassays, derivatives, conjugates and antibodies |
AU659501B2 (en) * | 1991-10-23 | 1995-05-18 | Biota Scientific Management Pty Ltd | Antiviral 4-substituted-2-deoxy-2,3-didehydro-derivatives of alpha-D-neuraminic acid |
WO1994011005A1 (en) * | 1992-11-09 | 1994-05-26 | Scientific Dimensions Usa, Inc. | Viral attachment inhibitors |
US5681811A (en) | 1993-05-10 | 1997-10-28 | Protein Delivery, Inc. | Conjugation-stabilized therapeutic agent compositions, delivery and diagnostic formulations comprising same, and method of making and using the same |
GB9410817D0 (en) | 1994-05-28 | 1994-07-20 | Glaxo Group Ltd | Medicaments |
HU228450B1 (en) * | 1995-02-27 | 2013-03-28 | Gilead Sciences Inc | Novel selective inhibitors of viral or bacterial neuraminidases |
GB9516276D0 (en) | 1995-08-08 | 1995-10-11 | Biota Scient Management | Chemical compounds |
DE69721242T2 (de) | 1996-03-01 | 2004-01-29 | Biota Scient Management | Verfahren zum nachweis von influenza-virus und dazu verwendbare verbindungen |
AUPO104396A0 (en) | 1996-07-17 | 1996-08-08 | Biomolecular Research Institute Limited | Antiviral linear polymers |
AUPP913999A0 (en) * | 1999-03-12 | 1999-04-01 | Biota Scientific Management Pty Ltd | Novel chemical compounds and their use |
-
1997
- 1997-11-13 US US09/308,076 patent/US6680054B1/en not_active Expired - Fee Related
- 1997-11-13 EP EP97911065A patent/EP0951480A4/en not_active Withdrawn
- 1997-11-13 EA EA199900459A patent/EA001603B1/ru not_active IP Right Cessation
- 1997-11-13 JP JP52195898A patent/JP3691075B2/ja not_active Expired - Fee Related
- 1997-11-13 CA CA2271249A patent/CA2271249C/en not_active Expired - Fee Related
- 1997-11-13 AP APAP/P/1999/001531A patent/AP9901531A0/en unknown
- 1997-11-13 HU HU9904009A patent/HUP9904009A3/hu unknown
- 1997-11-13 WO PCT/AU1997/000771 patent/WO1998021243A1/en not_active Application Discontinuation
- 1997-11-13 CZ CZ991679A patent/CZ167999A3/cs unknown
- 1997-11-13 NZ NZ335368A patent/NZ335368A/en unknown
- 1997-11-13 TR TR1999/01081T patent/TR199901081T2/xx unknown
- 1997-11-13 BR BR9714299-9A patent/BR9714299A/pt not_active Application Discontinuation
- 1997-11-13 IL IL12976297A patent/IL129762A0/xx unknown
- 1997-11-13 CN CN97199728A patent/CN1238783A/zh active Pending
- 1997-11-13 AU AU48576/97A patent/AU732916C/en not_active Ceased
- 1997-11-13 PL PL97333364A patent/PL333364A1/xx unknown
- 1997-11-13 KR KR1019997004301A patent/KR20000068986A/ko not_active Application Discontinuation
-
1999
- 1999-04-30 IS IS5044A patent/IS5044A/is unknown
- 1999-05-12 NO NO992297A patent/NO992297L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0951480A4 (en) | 2004-07-28 |
EA001603B1 (ru) | 2001-06-25 |
CA2271249A1 (en) | 1998-05-22 |
HUP9904009A3 (en) | 2001-07-30 |
JP3691075B2 (ja) | 2005-08-31 |
KR20000068986A (ko) | 2000-11-25 |
CZ167999A3 (cs) | 1999-10-13 |
CA2271249C (en) | 2010-07-20 |
WO1998021243A1 (en) | 1998-05-22 |
US6680054B1 (en) | 2004-01-20 |
NO992297D0 (no) | 1999-05-12 |
AP9901531A0 (en) | 1999-05-13 |
AU732916C (en) | 2002-06-06 |
HUP9904009A2 (hu) | 2000-03-28 |
EP0951480A1 (en) | 1999-10-27 |
IL129762A0 (en) | 2000-02-29 |
NZ335368A (en) | 2001-08-31 |
TR199901081T2 (xx) | 1999-08-23 |
JP2001504876A (ja) | 2001-04-10 |
PL333364A1 (en) | 1999-12-06 |
EA199900459A1 (ru) | 1999-12-29 |
AU4857697A (en) | 1998-06-03 |
CN1238783A (zh) | 1999-12-15 |
NO992297L (no) | 1999-07-12 |
AU732916B2 (en) | 2001-05-03 |
IS5044A (is) | 1999-04-30 |
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B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B07A | Application suspended after technical examination (opinion) [chapter 7.1 patent gazette] | ||
B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) 8O, 11 E 37 DA LPI |
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B09B | Patent application refused [chapter 9.2 patent gazette] |
Free format text: MANTIDO O INDEFERIMENTO UMA VEZ QUE NAO FOI APRESENTADO RECURSO DENTRO DO PRAZO LEGAL. |
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B15K | Others concerning applications: alteration of classification |
Free format text: PROCEDIMENTO AUTOMATICO DE RECLASSIFICACAO. AS CLASSIFICACOES IPC ANTERIORES ERAM: C07K 14/765; C07K 16/06; C07K 14/77; C08B 37/02; C12Q 1/70; C08G 69/48; C08F 8/32; G01N 33/569; A61K 38/38; A61K 31/785; A61K 31/73. Ipc: G01N 33/569 (2006.01), C08B 37/02 (2006.01), C08F Ipc: G01N 33/569 (2006.01), C08B 37/02 (2006.01), C08F |