BR9612146A - Compsostos de oligopeptídeo contendo d-2alquiltriptofano capazes de promover a liberação de hormônio de crescimento - Google Patents

Compsostos de oligopeptídeo contendo d-2alquiltriptofano capazes de promover a liberação de hormônio de crescimento

Info

Publication number
BR9612146A
BR9612146A BR9612146A BR9612146A BR9612146A BR 9612146 A BR9612146 A BR 9612146A BR 9612146 A BR9612146 A BR 9612146A BR 9612146 A BR9612146 A BR 9612146A BR 9612146 A BR9612146 A BR 9612146A
Authority
BR
Brazil
Prior art keywords
mrp
promoting
release
growth hormone
hydrogen
Prior art date
Application number
BR9612146A
Other languages
English (en)
Inventor
Romano Deghenghi
Original Assignee
Romano Deghenghi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Romano Deghenghi filed Critical Romano Deghenghi
Publication of BR9612146A publication Critical patent/BR9612146A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
BR9612146A 1995-12-20 1996-12-04 Compsostos de oligopeptídeo contendo d-2alquiltriptofano capazes de promover a liberação de hormônio de crescimento BR9612146A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95MI002681A IT1277113B1 (it) 1995-12-20 1995-12-20 Composti oligopeptidici contenenti d-2-alchiltriptofano in grado di promuovere la liberazione dell'ormone della crescita
PCT/EP1996/005393 WO1997022620A1 (en) 1995-12-20 1996-12-04 Oligopeptide compounds containing d-2-alkyltryptophan capable of promoting the release of growth hormone

Publications (1)

Publication Number Publication Date
BR9612146A true BR9612146A (pt) 1999-07-13

Family

ID=11372755

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9612146A BR9612146A (pt) 1995-12-20 1996-12-04 Compsostos de oligopeptídeo contendo d-2alquiltriptofano capazes de promover a liberação de hormônio de crescimento

Country Status (19)

Country Link
EP (1) EP0868429B1 (pt)
JP (1) JP2000502089A (pt)
KR (1) KR100369104B1 (pt)
CN (1) CN1126759C (pt)
AT (1) ATE226214T1 (pt)
AU (1) AU1175997A (pt)
BR (1) BR9612146A (pt)
CA (1) CA2239702C (pt)
DE (1) DE69624371T2 (pt)
DK (1) DK0868429T3 (pt)
ES (1) ES2186810T3 (pt)
HK (1) HK1016193A1 (pt)
IL (1) IL124507A (pt)
IT (1) IT1277113B1 (pt)
MX (1) MX9804868A (pt)
PT (1) PT868429E (pt)
RU (1) RU2182156C2 (pt)
WO (1) WO1997022620A1 (pt)
ZA (1) ZA9610591B (pt)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE470671T1 (de) 1998-01-16 2010-06-15 Helsinn Therapeutics Us Inc Verbindungen mit wachstumshormon-freisetzender eigenschaft
US5932548A (en) * 1998-06-03 1999-08-03 Deghenghi; Romano Lysine containing peptides for treatment of heart disease
US6919315B1 (en) 1998-06-30 2005-07-19 Novo Nordisk A/S Compounds with growth hormone releasing properties
EP1930021A3 (en) 1999-02-18 2008-06-18 Kaken Pharmaceutical Co., Ltd. Novel amide derivatives as growth hormone secretagogues
US6417397B1 (en) 1999-10-04 2002-07-09 The Regents Of The University Of California, San Diego N-substituted alkylamino acids for use as amino-protecting groups
US6211156B1 (en) * 1999-11-10 2001-04-03 Asta Medica A.G. Peptides for treatment of erectile dysfunction
DE60140285D1 (de) 2000-05-31 2009-12-10 Pfizer Prod Inc Verwendung von Wachstumshormonsekretagoga zur Förderung der Beweglichkeit des Verdauungstrakts
US7476653B2 (en) 2003-06-18 2009-01-13 Tranzyme Pharma, Inc. Macrocyclic modulators of the ghrelin receptor
WO2005105828A1 (en) * 2004-04-28 2005-11-10 Romano Deghenghi Pseudopeptides growth hormone secretagogues
GB0603295D0 (en) 2006-02-18 2006-03-29 Ardana Bioscience Ltd Methods and kits
CU23558A1 (es) 2006-02-28 2010-07-20 Ct Ingenieria Genetica Biotech Compuestos análogos a los secretagogos peptidicos de la hormona de crecimiento
EP2644618B1 (en) 2007-02-09 2016-08-17 Ocera Therapeutics, Inc. tether intermediates for the synthesis of macrocyclic ghrelin receptor modulators
US9119832B2 (en) 2014-02-05 2015-09-01 The Regents Of The University Of California Methods of treating mild brain injury
US20170121385A1 (en) 2015-10-28 2017-05-04 Oxeia Biopharmaceuticals, Inc. Methods of treating neurodegenerative conditions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1175810A (en) * 1979-03-30 1984-10-09 Frank A. Momany Synthetic peptides having pituitary growth hormone releasing activity
IT1240643B (it) * 1990-05-11 1993-12-17 Mediolanum Farmaceutici Spa Peptidi biologicamente attivi contenenti in catena 2-alchiltriptofano
CZ291798B6 (cs) * 1994-09-27 2003-05-14 Romano Deghenghi Peptidy, jejich použití a farmaceutický prostředek s jejich obsahem

Also Published As

Publication number Publication date
ATE226214T1 (de) 2002-11-15
IL124507A0 (en) 1998-12-06
ZA9610591B (en) 1997-06-24
HK1016193A1 (en) 1999-10-29
PT868429E (pt) 2003-02-28
ES2186810T3 (es) 2003-05-16
KR100369104B1 (ko) 2003-06-12
EP0868429A1 (en) 1998-10-07
MX9804868A (es) 1998-10-31
CA2239702C (en) 2007-08-07
DE69624371D1 (de) 2002-11-21
CN1126759C (zh) 2003-11-05
ITMI952681A0 (pt) 1995-12-20
EP0868429B1 (en) 2002-10-16
RU2182156C2 (ru) 2002-05-10
WO1997022620A1 (en) 1997-06-26
ITMI952681A1 (it) 1997-06-20
CN1204341A (zh) 1999-01-06
JP2000502089A (ja) 2000-02-22
KR20000064444A (ko) 2000-11-06
DK0868429T3 (da) 2003-02-10
DE69624371T2 (de) 2003-06-18
CA2239702A1 (en) 1997-06-26
AU1175997A (en) 1997-07-14
IT1277113B1 (it) 1997-11-04
IL124507A (en) 2001-03-19

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Legal Events

Date Code Title Description
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 04/12/1996, OBSERVADAS AS CONDICOES LEGAIS.

B24C Patent annual fee: request for for restoration

Free format text: REFERENTE A 13A E 14A ANUIDADE(S).

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE A DESPACHO 24.3, PUBLICADO NA RPI 2107 DE 24/05/2011.