ES2001953A6 - Procedimiento para la obtencion de compuestos de b -lactama. - Google Patents

Procedimiento para la obtencion de compuestos de b -lactama.

Info

Publication number
ES2001953A6
ES2001953A6 ES8601778A ES8601778A ES2001953A6 ES 2001953 A6 ES2001953 A6 ES 2001953A6 ES 8601778 A ES8601778 A ES 8601778A ES 8601778 A ES8601778 A ES 8601778A ES 2001953 A6 ES2001953 A6 ES 2001953A6
Authority
ES
Spain
Prior art keywords
compounds
image
beta
synthesis
formulae
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES8601778A
Other languages
English (en)
Inventor
Ernst Hungerbuhler
Jaroslav Kalvoda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES2001953A6 publication Critical patent/ES2001953A6/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D499/88—Compounds with a double bond between positions 2 and 3 and a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
  • Pyrrole Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS DE B-LACTAMA, DE FORMULA I O LAS SALES DE ESTOS, DONDE R1, R2 Y R3 TIENEN LOS SIGNIFICADOS ANTERIORMENTE INDICADOS POR TRATAMIENTO DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO INTRODUCTOR DEL RESTO ACIDO TIOCARBOXILICO DE FORMULA (III) ESTOS COMPUESTOS TIENEN ESPECIALMENTE ACTIVIDAD ANTIBIOTICA.
ES8601778A 1985-09-11 1986-09-10 Procedimiento para la obtencion de compuestos de b -lactama. Expired ES2001953A6 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH392885 1985-09-11
CH91986 1986-03-06

Publications (1)

Publication Number Publication Date
ES2001953A6 true ES2001953A6 (es) 1988-07-01

Family

ID=25686111

Family Applications (1)

Application Number Title Priority Date Filing Date
ES8601778A Expired ES2001953A6 (es) 1985-09-11 1986-09-10 Procedimiento para la obtencion de compuestos de b -lactama.

Country Status (9)

Country Link
US (2) US4962196A (es)
EP (1) EP0215739B1 (es)
AT (1) ATE93861T1 (es)
DE (1) DE3688960D1 (es)
DK (1) DK432086A (es)
ES (1) ES2001953A6 (es)
HU (1) HU198065B (es)
IE (1) IE60451B1 (es)
PT (1) PT83334B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5215997A (en) * 1985-09-11 1993-06-01 Ciba-Geigy Corporation Synthesis of beta-lactam compounds
DE3688960D1 (de) * 1985-09-11 1993-10-07 Ciba Geigy Synthese von Beta-Lactamverbindungen.
EP0290385B1 (de) 1987-05-04 1992-10-21 Ciba-Geigy Ag Neues Verfahren zur Herstellung von 4-Acyloxy-3-hydroxyethyl-azetidinonen
JP2992314B2 (ja) * 1989-07-26 1999-12-20 サントリー株式会社 アリル基の除去方法
GB9006114D0 (en) * 1990-03-19 1990-05-16 Erba Carlo Spa Process for preparing penem esters
US5399679A (en) * 1992-06-16 1995-03-21 Farmitalia Carlo Erba S.R.L. (1'R,3S,4R)4-acylthio azetidinones
US5587474A (en) * 1992-06-18 1996-12-24 Tanabe Seiyaku Co., Ltd. Method for removing the protecting group for carboxyl group
EP0597401A3 (en) * 1992-11-11 1995-07-26 Takeda Chemical Industries Ltd Preparation of penemes.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4347183A (en) * 1981-02-02 1982-08-31 Schering Corporation Process for the synthesis of penems and carbapenems
US4540579A (en) * 1982-11-16 1985-09-10 Schering Corporation 2-[(R) Amino acid alkyl]penems
EP0125208A1 (de) * 1983-05-06 1984-11-14 Ciba-Geigy Ag Aminoniederalkyl-penem-Verbindungen, Verfahren zu ihrer Herstellung, pharmazeutische Präparate, welche diese Verbindungen enthalten, und Verwendung von letzteren
GB8321677D0 (en) * 1983-08-11 1983-09-14 Erba Farmitalia Preparation of penems
US4656165A (en) * 1983-09-02 1987-04-07 Ciba-Geigy Corporation Aminomethyl penem compounds
DE3688960D1 (de) * 1985-09-11 1993-10-07 Ciba Geigy Synthese von Beta-Lactamverbindungen.
US4826832A (en) * 1986-05-06 1989-05-02 Ciba-Geigy Corporation Penen compounds

Also Published As

Publication number Publication date
HU198065B (en) 1989-07-28
DE3688960D1 (de) 1993-10-07
EP0215739A1 (de) 1987-03-25
US5153315A (en) 1992-10-06
HUT41798A (en) 1987-05-28
DK432086D0 (da) 1986-09-10
IE60451B1 (en) 1994-07-13
ATE93861T1 (de) 1993-09-15
PT83334B (pt) 1989-05-12
IE862417L (en) 1987-03-11
US4962196A (en) 1990-10-09
EP0215739B1 (de) 1993-09-01
DK432086A (da) 1987-03-12
PT83334A (en) 1986-10-01

Similar Documents

Publication Publication Date Title
IL113313A0 (en) Heterocyclic compounds and pharmaceutical compositions containing the same
CA2247443A1 (en) Substituted 4-hydroxy-phenylalcanoic acid derivatives with agonist activity to ppar-gamma
NZ238181A (en) N-(1-substituted-piperidinyl(alkyl))carbamic acid, urea and carboxamide derivatives and homologues thereof; preparatory processes and pharmaceutical compositions
MY107756A (en) Piperazine derivatives.
PH20468A (en) Novel pharmaceutically active di-esters of 3,5-dicarboxy-4-substituted-pyridines and pyrans
GB2262093B (en) Piperazine derivatives
PH19270A (en) 2 azaspiro(4.(3+n)alkane 3-carboxylic acid derivatives
ES8801245A1 (es) Un procedimiento para preparar derivados de piperidina
HUT70506A (en) Pyridinecarboximidamide compounds, pharmaceutical compositions containing them and process for producing them
PL309874A1 (en) Novel derivatives of pyrrolocarbasol, method of obtaining them and pharmaceutical composition containing such derivatives
ES2001953A6 (es) Procedimiento para la obtencion de compuestos de b -lactama.
ES2044781A1 (es) Procedimiento para la preparacion de nuevas amidas con accion inhibidora de la fosfolipasa a2
EP0529452A3 (de) 1,7-anellierte 2-(Piperazino-alkyl)indol-Derivate sowie Verfahren und Zwischenprodukte zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
ES8301224A1 (es) Procedimiento para la preparacion de nuevas 5,10-dihidro -11h-dibenzo b,e 1,4 diazepin-11-onas, sustituidas en posi- cion 5
ES8306474A1 (es) Derivados de encefalina.
ATE217626T1 (de) Cephemverbindungen
ES8205770A1 (es) Procedimiento para la preparacion de derivados de 2,3-indo- lediona
ES2102327A1 (es) Nuevos derivados de 2,2,6,6-tetrametilpiperidina para utilizarse como agentes estabilizantes para materiales organicos contra la luz, el calor, y la oxidacion. n
UA43338C2 (uk) Похідні бензолу
HUT75647A (en) Imidazolidinone derivatives and pharmaceutical compositions containing them, which are suitable for treament of senile dementia
ES8200669A1 (es) Un procedimiento para la preparacion de nuevos compuestos iminicos heterociclicos
ES8304971A1 (es) Un procedimiento para la preparacion de derivados de tiocarbapenem 3-sustituidos.
CA2093510A1 (en) Oxysulfonyl carbamates
ES8303425A1 (es) Procedimiento para la preparacion de nuevas cefalosporinas
TW353662B (en) Cephalosporin salts and process for the preparation thereof

Legal Events

Date Code Title Description
SA6 Expiration date (snapshot 920101)

Free format text: 2006-09-10