BR9610475A - Preparação de hemoglobinas de grau farmacêutico por tratamento térmico em forma parcialmente oxigenada - Google Patents

Preparação de hemoglobinas de grau farmacêutico por tratamento térmico em forma parcialmente oxigenada

Info

Publication number
BR9610475A
BR9610475A BR9610475A BR9610475A BR9610475A BR 9610475 A BR9610475 A BR 9610475A BR 9610475 A BR9610475 A BR 9610475A BR 9610475 A BR9610475 A BR 9610475A BR 9610475 A BR9610475 A BR 9610475A
Authority
BR
Brazil
Prior art keywords
hemoglobins
preparation
heat treatment
pharmaceutical grade
partially oxygenated
Prior art date
Application number
BR9610475A
Other languages
English (en)
Inventor
Mahmood Rezazadeh Azari
August A Ebeling
John E Picken
Timothy N Estep
Original Assignee
Baxter Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Baxter Int filed Critical Baxter Int
Publication of BR9610475A publication Critical patent/BR9610475A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/795—Porphyrin- or corrin-ring-containing peptides
    • C07K14/805—Haemoglobins; Myoglobins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/30—Extraction; Separation; Purification by precipitation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • External Artificial Organs (AREA)
BR9610475A 1995-09-22 1996-08-20 Preparação de hemoglobinas de grau farmacêutico por tratamento térmico em forma parcialmente oxigenada BR9610475A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/532,293 US5741894A (en) 1995-09-22 1995-09-22 Preparation of pharmaceutical grade hemoglobins by heat treatment in partially oxygenated form
PCT/US1996/013511 WO1997010831A1 (en) 1995-09-22 1996-08-20 Preparation of pharmaceutical grade hemoglobins by heat treatment in partially oxygenated form

Publications (1)

Publication Number Publication Date
BR9610475A true BR9610475A (pt) 1999-05-11

Family

ID=24121176

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9610475A BR9610475A (pt) 1995-09-22 1996-08-20 Preparação de hemoglobinas de grau farmacêutico por tratamento térmico em forma parcialmente oxigenada

Country Status (13)

Country Link
US (1) US5741894A (pt)
EP (1) EP0854725B1 (pt)
JP (1) JP2000500736A (pt)
KR (1) KR19990063654A (pt)
CN (1) CN1197392A (pt)
AU (1) AU716742B2 (pt)
BR (1) BR9610475A (pt)
CA (1) CA2229845A1 (pt)
DE (1) DE69625605T2 (pt)
NO (1) NO981270L (pt)
TW (1) TW360660B (pt)
WO (1) WO1997010831A1 (pt)
ZA (1) ZA967319B (pt)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6747132B2 (en) 2000-11-29 2004-06-08 Apex Biosciences, Inc. Methods for the synthesis of a modified hemoglobin solution
US7038016B2 (en) 2001-08-21 2006-05-02 Apex Bioscience, Inc. Methods for purification of an activated PEG solution and for the synthesis of a modified hemoglobin solution
US20110319332A1 (en) * 2010-06-23 2011-12-29 Bing Lou Wong Treatment methods using a heat stable oxygen carrier-containing pharmaceutical composition
US7932356B1 (en) 2010-06-23 2011-04-26 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing pharmaceutical composition
US8084581B1 (en) 2011-04-29 2011-12-27 Bing Lou Wong Method for removing unmodified hemoglobin from cross-linked hemoglobin solutions including polymeric hemoglobin with a high temperature short time heat treatment apparatus
US20130052232A1 (en) 2011-08-31 2013-02-28 Bing Lou Wong Method for the preparation of a heat stable oxygen carrier-containing composition facilating beta-beta cross-linking
JP7387597B2 (ja) 2017-07-18 2023-11-28 ヴァーテック・バイオ・インコーポレイテッド ヘモグロビンを含む代用血液及び作製方法
KR20220082811A (ko) 2019-08-29 2022-06-17 빌리언 킹 인터네셔널 리미티드 티오숙시닐-가교 헤모글로빈 유사체 및 이의 사용 및 제조 방법
WO2024081928A1 (en) * 2022-10-14 2024-04-18 Prolong Pharmaceuticals Llc A stable hemoglobin protein composition

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Also Published As

Publication number Publication date
US5741894A (en) 1998-04-21
JP2000500736A (ja) 2000-01-25
EP0854725B1 (en) 2003-01-02
KR19990063654A (ko) 1999-07-26
NO981270D0 (no) 1998-03-20
TW360660B (en) 1999-06-11
WO1997010831A1 (en) 1997-03-27
AU6853096A (en) 1997-04-09
AU716742B2 (en) 2000-03-02
MX9802059A (es) 1998-08-30
DE69625605T2 (de) 2003-10-16
NO981270L (no) 1998-03-20
CA2229845A1 (en) 1997-03-27
CN1197392A (zh) 1998-10-28
ZA967319B (en) 1997-03-04
DE69625605D1 (de) 2003-02-06
EP0854725A1 (en) 1998-07-29
EP0854725A4 (en) 1999-11-17

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)