BR9508751A - Composto formulação e processos de tratamento ou profilaxia de disfunções psicóticas ou disfunções de debilitação intelectual e da ansiedade e de preparação do composto - Google Patents

Composto formulação e processos de tratamento ou profilaxia de disfunções psicóticas ou disfunções de debilitação intelectual e da ansiedade e de preparação do composto

Info

Publication number
BR9508751A
BR9508751A BR9508751A BR9508751A BR9508751A BR 9508751 A BR9508751 A BR 9508751A BR 9508751 A BR9508751 A BR 9508751A BR 9508751 A BR9508751 A BR 9508751A BR 9508751 A BR9508751 A BR 9508751A
Authority
BR
Brazil
Prior art keywords
disorders
compound
anxiety
prophylaxis
processes
Prior art date
Application number
BR9508751A
Other languages
English (en)
Portuguese (pt)
Inventor
Michael Balestra
John Charles Gordon
Ronald Conrad Griffith
Robert John Murray
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9417084A external-priority patent/GB9417084D0/en
Priority claimed from GBGB9504627.2A external-priority patent/GB9504627D0/en
Application filed by Astra Ab filed Critical Astra Ab
Publication of BR9508751A publication Critical patent/BR9508751A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BR9508751A 1994-08-24 1995-08-22 Composto formulação e processos de tratamento ou profilaxia de disfunções psicóticas ou disfunções de debilitação intelectual e da ansiedade e de preparação do composto BR9508751A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB9417084A GB9417084D0 (en) 1994-08-24 1994-08-24 Compounds useful in therapy
GBGB9504627.2A GB9504627D0 (en) 1995-03-08 1995-03-08 Compounds for use in therapy
PCT/SE1995/000937 WO1996006098A1 (en) 1994-08-24 1995-08-22 Spiro-azabicyclic compounds useful in therapy

Publications (1)

Publication Number Publication Date
BR9508751A true BR9508751A (pt) 1997-08-12

Family

ID=26305509

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9508751A BR9508751A (pt) 1994-08-24 1995-08-22 Composto formulação e processos de tratamento ou profilaxia de disfunções psicóticas ou disfunções de debilitação intelectual e da ansiedade e de preparação do composto

Country Status (34)

Country Link
US (2) US5902814A (ja)
EP (1) EP0777671B1 (ja)
JP (1) JP3708962B2 (ja)
KR (1) KR100366331B1 (ja)
CN (2) CN1056846C (ja)
AR (1) AR031828A2 (ja)
AT (1) ATE192157T1 (ja)
AU (1) AU690735B2 (ja)
BR (1) BR9508751A (ja)
CA (1) CA2196995C (ja)
CZ (1) CZ289512B6 (ja)
DE (1) DE69516524T2 (ja)
DK (1) DK0777671T3 (ja)
EE (1) EE03399B1 (ja)
EG (1) EG24222A (ja)
ES (1) ES2145922T3 (ja)
FI (1) FI112868B (ja)
GR (1) GR3033878T3 (ja)
HK (1) HK1010370A1 (ja)
HU (1) HUT77352A (ja)
IL (1) IL115039A (ja)
IS (1) IS1852B (ja)
MX (1) MX9701292A (ja)
NO (1) NO307707B1 (ja)
NZ (1) NZ292289A (ja)
PL (1) PL183933B1 (ja)
PT (1) PT777671E (ja)
RU (1) RU2148058C1 (ja)
SA (1) SA95160370B1 (ja)
SK (1) SK282366B6 (ja)
TR (1) TR199501053A2 (ja)
TW (1) TW397837B (ja)
UA (1) UA54375C2 (ja)
WO (1) WO1996006098A1 (ja)

Families Citing this family (84)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5977144A (en) * 1992-08-31 1999-11-02 University Of Florida Methods of use and compositions for benzylidene- and cinnamylidene-anabaseines
AR013184A1 (es) * 1997-07-18 2000-12-13 Astrazeneca Ab Aminas heterociclicas espiroazobiciclicas, composicion farmaceutica, uso de dichas aminas para preparar medicamentos y metodo de tratamiento o profilaxis
US6277870B1 (en) * 1998-05-04 2001-08-21 Astra Ab Use
SE9900100D0 (sv) 1999-01-15 1999-01-15 Astra Ab New compounds
JP4564135B2 (ja) * 1999-07-26 2010-10-20 住友化学株式会社 高純度フェノチアジン化合物とその製造方法、およびその中間体の製造方法、並びにその中間体の原料の水和物と新規結晶
WO2001066546A1 (fr) * 2000-03-09 2001-09-13 Mitsubishi Pharma Corporation Composes spiro, leur procede de preparation et leur utilisation comme medicaments
US8914114B2 (en) 2000-05-23 2014-12-16 The Feinstein Institute For Medical Research Inhibition of inflammatory cytokine production by cholinergic agonists and vagus nerve stimulation
WO2002018391A1 (en) * 2000-08-28 2002-03-07 Colorado State University Research Foundation Compounds containing oxazolidinone moiety and uses thereof
US6569865B2 (en) 2001-06-01 2003-05-27 Astrazeneca Ab Spiro 1-azabicyclo[2.2.2]octane-3,2′(3′h)-furo[2,3-b]pyridine
EP1453828A2 (en) * 2001-10-16 2004-09-08 AstraZeneca AB Azabicyclic compounds for the treatment of fibromyalgia syndrome
DE10164139A1 (de) 2001-12-27 2003-07-10 Bayer Ag 2-Heteroarylcarbonsäureamide
CA2476896A1 (en) * 2002-02-26 2003-09-04 North Shore-Long Island Jewish Research Institute Inhibition of inflammatory cytokine production by stimulation of brain muscarinic receptors
SE0202598D0 (sv) * 2002-09-02 2002-09-02 Astrazeneca Ab Alpha-7 Nicotinic receptor agonists and statins in combination
US7238715B2 (en) * 2002-12-06 2007-07-03 The Feinstein Institute For Medical Research Treatment of pancreatitis using alpha 7 receptor-binding cholinergic agonists
EP2062595A1 (en) * 2002-12-06 2009-05-27 The Feinstein Institute for Medical Research Inhibition of inflammation using alpha 7 receptor-binding cholinergic agonists
JP2007516200A (ja) * 2003-07-08 2007-06-21 アストラゼネカ・アクチエボラーグ α７ニコチン性アセチルコリン受容体に親和性を有するスピロ［１−アザビシクロ［２，２，２］オクタン−３，５’−オキサゾリジン］−２’−オン誘導体
WO2005092308A2 (en) * 2004-03-25 2005-10-06 The Feinstein Institute For Medical Research Neural tourniquet
US10912712B2 (en) 2004-03-25 2021-02-09 The Feinstein Institutes For Medical Research Treatment of bleeding by non-invasive stimulation
WO2006065209A1 (en) * 2004-12-15 2006-06-22 Astrazeneca Ab Nicotinic acetylcholine receptor ligands
US11207518B2 (en) 2004-12-27 2021-12-28 The Feinstein Institutes For Medical Research Treating inflammatory disorders by stimulation of the cholinergic anti-inflammatory pathway
DE602005025020D1 (de) 2004-12-27 2011-01-05 The Feinstein Inst Medical Res Behandlung von entzündlichen erkrankungen durch el
JP2008525524A (ja) * 2004-12-28 2008-07-17 アストラゼネカ・アクチエボラーグ アリールスルホンアミドモジュレーター
CA2620333A1 (en) 2005-08-26 2007-03-01 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
EP2258359A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis by muscarinic receptor modulation with sabcomelin
US8316104B2 (en) 2005-11-15 2012-11-20 California Institute Of Technology Method and apparatus for collaborative system
WO2008028903A2 (en) 2006-09-04 2008-03-13 Neurosearch A/S Pharmaceutical combinations of a nicotine receptor modulator and a cognitive enhancer
BRPI0716604A2 (pt) 2006-09-08 2013-04-09 Braincells Inc combinaÇÕes contendo um derivado de 4-acilaminopiridina
WO2009029614A1 (en) 2007-08-27 2009-03-05 The Feinstein Institute For Medical Research Devices and methods for inhibiting granulocyte activation by neural stimulation
DE102008015999B4 (de) 2008-03-27 2011-04-21 Novar Gmbh Übertragungsweg - Prüfverfahren für eine Gefahrenmeldeanlage
US9662490B2 (en) 2008-03-31 2017-05-30 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation and administration of an anti-inflammatory drug
WO2009146030A1 (en) * 2008-03-31 2009-12-03 The Feinstein Institute For Medical Research Methods and systems for reducing inflammation by neuromodulation of t-cell activity
US7863291B2 (en) * 2008-04-23 2011-01-04 Bristol-Myers Squibb Company Quinuclidine compounds as alpha-7 nicotinic acetylcholine receptor ligands
US8309577B2 (en) 2008-04-23 2012-11-13 Bristol-Myers Squibb Company Quinuclidine compounds as α-7 nicotinic acetylcholine receptor ligands
UA105903C2 (uk) 2008-06-20 2014-07-10 Астразенека Аб Похідні дибензотіазепіну та їх застосування
AU2009316801C1 (en) 2008-11-18 2015-12-24 Setpoint Medical Corporation Devices and methods for optimizing electrode placement for anti-inflammatory stimulation
BRPI0922057A2 (pt) 2008-11-19 2015-12-15 Envivo Pharmaceuticals Inc tratamento dos transtorno cognitivos com (r)-7-cloro-n-(quiniclidin-3-il)benzo[b]tiofeno-2-carboxamida e sais farmeceuticamente aceitaveis do mesmo
TW201031664A (en) 2009-01-26 2010-09-01 Targacept Inc Preparation and therapeutic applications of (2S,3R)-N-2-((3-pyridinyl)methyl)-1-azabicyclo[2.2.2]oct-3-yl)-3,5-difluorobenzamide
US8788034B2 (en) 2011-05-09 2014-07-22 Setpoint Medical Corporation Single-pulse activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US9211410B2 (en) 2009-05-01 2015-12-15 Setpoint Medical Corporation Extremely low duty-cycle activation of the cholinergic anti-inflammatory pathway to treat chronic inflammation
US8996116B2 (en) 2009-10-30 2015-03-31 Setpoint Medical Corporation Modulation of the cholinergic anti-inflammatory pathway to treat pain or addiction
CN102802620A (zh) * 2009-05-11 2012-11-28 英维沃医药有限公司 使用某种α-7烟酸受体与乙酰胆碱酯酶抑制剂结合治疗认知障碍
WO2010144578A2 (en) 2009-06-09 2010-12-16 Setpoint Medical Corporation Nerve cuff with pocket for leadless stimulator
US8278320B2 (en) 2009-10-28 2012-10-02 Bristol-Myers Squibb Company Azabicyclo[2.2.1]heptane compounds as alpha-7 nicotinic acetylcholine receptor ligands
US8507516B2 (en) 2009-10-28 2013-08-13 Bristol-Myers Squibb Company Azabicyclic compounds as alpha-7 nicotinic acetylcholine receptor ligands
US11051744B2 (en) 2009-11-17 2021-07-06 Setpoint Medical Corporation Closed-loop vagus nerve stimulation
US9833621B2 (en) 2011-09-23 2017-12-05 Setpoint Medical Corporation Modulation of sirtuins by vagus nerve stimulation
EP2515996B1 (en) 2009-12-23 2019-09-18 Setpoint Medical Corporation Neural stimulation devices and systems for treatment of chronic inflammation
EP2563796B1 (en) 2010-04-30 2015-03-18 Bristol-Myers Squibb Company Aza-bicyclic amine n-oxide compounds as alpha-7 nicotinic acetylcholine receptor ligand pro-drugs
UY33389A (es) 2010-05-17 2011-12-30 Mitsubishi Tanabe Pharma Corp Una forma cristalina de clorhidrato de (r)-7-cloro-n-(quinuclidin-3-il)benzo[b]tiofeno-2-carboxamida monohidrato
GB201111705D0 (en) 2011-07-07 2011-08-24 Takeda Pharmaceutical Compounds and their use
GB201111704D0 (en) 2011-07-07 2011-08-24 Takeda Pharmaceutical Novel compounds
JO3115B1 (ar) 2011-08-22 2017-09-20 Takeda Pharmaceuticals Co مركبات بيريدازينون واستخدامها كمثبطات daao
US9572983B2 (en) 2012-03-26 2017-02-21 Setpoint Medical Corporation Devices and methods for modulation of bone erosion
RU2017136693A (ru) 2012-05-08 2019-02-08 Форум Фармасьютикалз, Инк. Способы поддержания, лечения или улучшения когнитивной функции
GB201209587D0 (en) 2012-05-30 2012-07-11 Takeda Pharmaceutical Therapeutic compounds
US9593106B2 (en) 2013-02-07 2017-03-14 Heptares Therapeutics Limited Piperidin-1-yl and azepin-1-yl carboxylates as muscarinic M4 receptor agonists
CA2914263C (en) 2013-06-21 2021-05-18 Takeda Pharmaceutical Company Limited 1-sulfonyl piperidine derivatives as modulators of prokineticin receptors
GB201314286D0 (en) 2013-08-08 2013-09-25 Takeda Pharmaceutical Therapeutic Compounds
GB201318222D0 (en) 2013-10-15 2013-11-27 Takeda Pharmaceutical Novel compounds
GB201320905D0 (en) 2013-11-27 2014-01-08 Takeda Pharmaceutical Therapeutic compounds
TW201613864A (en) 2014-02-20 2016-04-16 Takeda Pharmaceutical Novel compounds
US11311725B2 (en) 2014-10-24 2022-04-26 Setpoint Medical Corporation Systems and methods for stimulating and/or monitoring loci in the brain to treat inflammation and to enhance vagus nerve stimulation
US11406833B2 (en) 2015-02-03 2022-08-09 Setpoint Medical Corporation Apparatus and method for reminding, prompting, or alerting a patient with an implanted stimulator
US10596367B2 (en) 2016-01-13 2020-03-24 Setpoint Medical Corporation Systems and methods for establishing a nerve block
US11471681B2 (en) 2016-01-20 2022-10-18 Setpoint Medical Corporation Batteryless implantable microstimulators
US10314501B2 (en) 2016-01-20 2019-06-11 Setpoint Medical Corporation Implantable microstimulators and inductive charging systems
CN108882885A (zh) 2016-01-20 2018-11-23 赛博恩特医疗器械公司 迷走神经刺激的控制
US10583304B2 (en) 2016-01-25 2020-03-10 Setpoint Medical Corporation Implantable neurostimulator having power control and thermal regulation and methods of use
US10661112B2 (en) 2016-07-25 2020-05-26 Tonal Systems, Inc. Digital strength training
US11745039B2 (en) 2016-07-25 2023-09-05 Tonal Systems, Inc. Assisted racking of digital resistance
GB201616839D0 (en) 2016-10-04 2016-11-16 Takeda Pharmaceutical Company Limited Therapeutic compounds
GB201619514D0 (en) 2016-11-18 2017-01-04 Takeda Pharmaceuticals Co Novel compounds
WO2019036470A1 (en) 2017-08-14 2019-02-21 Setpoint Medical Corporation TESTING TEST FOR STIMULATION OF NERVE WAVE
US10335626B2 (en) 2017-10-02 2019-07-02 Tonal Systems, Inc. Exercise machine with pancake motor
US10486015B2 (en) 2017-10-02 2019-11-26 Tonal Systems, Inc. Exercise machine enhancements
US10589163B2 (en) 2017-10-02 2020-03-17 Tonal Systems, Inc. Exercise machine safety enhancements
US10617903B2 (en) 2017-10-02 2020-04-14 Tonal Systems, Inc. Exercise machine differential
US11660443B2 (en) 2018-04-20 2023-05-30 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via electrical trigeminal nerve stimulation
US11260229B2 (en) 2018-09-25 2022-03-01 The Feinstein Institutes For Medical Research Methods and apparatuses for reducing bleeding via coordinated trigeminal and vagal nerve stimulation
JP2021138648A (ja) 2020-03-04 2021-09-16 武田薬品工業株式会社 経口固形製剤
IL298193B2 (en) 2020-05-21 2024-01-01 Feinstein Institutes For Medical Research Systems and methods for stimulating the vagus nerve
US11285355B1 (en) 2020-06-08 2022-03-29 Tonal Systems, Inc. Exercise machine enhancements
US11998804B2 (en) 2021-04-27 2024-06-04 Tonal Systems, Inc. Repetition phase detection
US11878204B2 (en) 2021-04-27 2024-01-23 Tonal Systems, Inc. First repetition detection

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH601304A5 (ja) * 1974-02-12 1978-07-14 Buskine Sa
US4028351A (en) * 1971-09-07 1977-06-07 Buskine S.A. Method for the preparation of derivatives of spiro (4,5)-decane and derivatives thus obtained
GB8808433D0 (en) * 1988-04-11 1988-05-11 Merck Sharp & Dohme Therapeutic agents
GB8816299D0 (en) * 1988-07-08 1988-08-10 Merck Sharp & Dohme Therapeutic agents
IL97726A (en) * 1990-04-10 1994-12-29 Israel Inst Biolog Res Pharmaceutical preparations containing compounds with bridged and unbridged heterocyclic groups connected via spiro-atop with oxazoline and thiazoline groups, and sharp compounds
US5534520A (en) * 1990-04-10 1996-07-09 Fisher; Abraham Spiro compounds containing five-membered rings
US5073560A (en) * 1990-07-20 1991-12-17 Fisons Corporation Spiro-isoxazolidine derivatives as cholinergic agents
US5137895A (en) * 1991-04-29 1992-08-11 A. H. Robins Company, Incorporated 3-[N-aroyl(or thioaroyl)aminomethyl]-3-quinuclidinols

Also Published As

Publication number Publication date
IL115039A (en) 2001-08-26
IS1852B (is) 2003-02-21
ATE192157T1 (de) 2000-05-15
CN1099419C (zh) 2003-01-22
HUT77352A (hu) 1998-03-30
NO307707B1 (no) 2000-05-15
DE69516524D1 (de) 2000-05-31
JPH10504561A (ja) 1998-05-06
CA2196995A1 (en) 1996-02-29
MX9701292A (es) 1997-05-31
CN1284505A (zh) 2001-02-21
NZ292289A (en) 1998-05-27
IS4424A (is) 1997-02-03
FI112868B (fi) 2004-01-30
TR199501053A2 (tr) 1996-06-21
CZ39297A3 (en) 1997-12-17
FI970762A0 (fi) 1997-02-24
PT777671E (pt) 2000-08-31
DE69516524T2 (de) 2001-01-18
EG24222A (en) 2008-11-10
HK1010370A1 (en) 1999-06-17
US6051581A (en) 2000-04-18
SA95160370B1 (ar) 2006-06-04
ES2145922T3 (es) 2000-07-16
AR031828A2 (es) 2003-10-08
CA2196995C (en) 2008-05-13
EE03399B1 (et) 2001-04-16
PL183933B1 (pl) 2002-08-30
EP0777671B1 (en) 2000-04-26
RU2148058C1 (ru) 2000-04-27
EE9700039A (et) 1997-08-15
NO970800D0 (no) 1997-02-21
CN1056846C (zh) 2000-09-27
FI970762A (fi) 1997-02-24
KR100366331B1 (ko) 2003-04-10
AU3401895A (en) 1996-03-14
EP0777671A1 (en) 1997-06-11
JP3708962B2 (ja) 2005-10-19
TW397837B (en) 2000-07-11
NO970800L (no) 1997-02-21
IL115039A0 (en) 1995-12-08
PL318760A1 (en) 1997-07-07
CN1159808A (zh) 1997-09-17
CZ289512B6 (cs) 2002-02-13
GR3033878T3 (en) 2000-11-30
SK21697A3 (en) 1997-09-10
SK282366B6 (sk) 2002-01-07
WO1996006098A1 (en) 1996-02-29
UA54375C2 (uk) 2003-03-17
US5902814A (en) 1999-05-11
AU690735B2 (en) 1998-04-30
DK0777671T3 (da) 2000-07-24

Similar Documents

Publication Publication Date Title
BR9508751A (pt) Composto formulação e processos de tratamento ou profilaxia de disfunções psicóticas ou disfunções de debilitação intelectual e da ansiedade e de preparação do composto
EE9900607A (et) Imidasopürimidiinid ja imidasopüridiinid neuroloogiliste häirete käitlemiseks
BR9406128A (pt) Uso de um composto processo para o tratamento e/ou prevençao de distúrbios psicóticos composto composiçao farmacêutica processos para a preparaçao de um composto e de uma composiçao farmacêutica
DE69725484D1 (de) Vorrichtung zur Behandlung von Harninkontinenz
FI971969A0 (fi) Peräpukamien hoitoon tarkoitettuja koostumuksia ja käyttömenetelmä
EP0776210A4 (en) METHOD FOR PROPHYLAXIS AND / OR TREATMENT OF PROLIFERATIVE AND / OR INFLAMMATORY CONDITIONS OF THE SKIN
EE9700267A (et) a1L- agonistide kasutamine uriiniinkontinentsuse raviks
HUP0400719A3 (en) Compounds and methods for treatment and diagnosis of chlamydial infection
FI952169A0 (fi) Stabiili valmiste veren koagulaatiohäiriöiden hoitamiseksi
MA24437A1 (fr) Procede de la preparation et de la formulation de dihydrate d'eprosartan
GB2311940B (en) Pharmaceutical compositions for the treatment of rhinitis
ATE318604T1 (de) Neue therapeutische kombinationen aus mirtazapin und antipsychotika, zur behandlung oder prophylaxe von psychotischen störungen
BR9506581A (pt) Composto composição farmacêutica uso do composto processo para a profilaxia ou tratamento de uma condição clínica em um manífero por exemplo um humano e para a preparação de um composto e composto intermediário
BR9605984A (pt) Artigo higiênico capaz de aperfeiçoar o encaixe contra o corpo e método e aparelho para manufaturar o mesmo
BR9710376A (pt) Composto antiviral uso do mesmo composi-Æo farmac-utica e processo para tratamento antiviral profil tico ou terap-utico de um animal humano ou nÆo humano
DE69620691D1 (de) Therapeutisches Mittel zur Behandlung der Hypercholesterinämie
ID21948A (id) Penggunaan 1-hidroksi-2piridon untuk pengobatan infeksi-infeksi kulit
ID27214A (id) Triazolopiridina untuk pengobatan gangguan trombosis
AU7310896A (en) Use of nitroflavonoids for the treatment of anxiety
BR9612234A (pt) Composto processo para preparação do mesmo uso do composto e processos para tratamento de doenças das vias aéreas e tratamento ou profilaxia de glaucoma
EP0699384A3 (en) Material for the treatment of animal excrement and process for its manufacture
ATE230741T1 (de) 3-tetrahydropyridin-4-yl-indole zur behandlung von psychotischen störungen
IL140540A0 (en) Treatment of anxiety disorders
DE69720410D1 (de) Therapeutisches Mittel zur Behandlung hartnäckiger Hundedermatitis
BR9507732A (pt) Composição farmacêutica para o tratamento de glaucoma

Legal Events

Date Code Title Description
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
FB36 Technical and formal requirements: requirement - article 36 of industrial property law
HJEG Technical examination (opinion): technical examination (opinion) related to article 229 of industrial property law
FF Decision: intention to grant
FG9A Patent or certificate of addition granted
B24H Lapse because of non-payment of annual fees (definitively: art 78 iv lpi)
B24F Patent annual fee: publication cancelled

Free format text: ANULADA A PUBLICACAO CODIGO 24.8 NA RPI NO 2257 DE 08/04/2014 POR TER SIDO INDEVIDA.

B21F Lapse acc. art. 78, item iv - on non-payment of the annual fees in time

Free format text: REFERENTE AS 15A, 16A, 17A, 18A, 19A E 20A ANUIDADES.

B24J Lapse because of non-payment of annual fees (definitively: art 78 iv lpi, resolution 113/2013 art. 12)

Free format text: EM VIRTUDE DA EXTINCAO PUBLICADA NA RPI 2607 DE 22-12-2020 E CONSIDERANDO AUSENCIA DE MANIFESTACAO DENTRO DOS PRAZOS LEGAIS, INFORMO QUE CABE SER MANTIDA A EXTINCAO DA PATENTE E SEUS CERTIFICADOS, CONFORME O DISPOSTO NO ARTIGO 12, DA RESOLUCAO 113/2013.