BR8506312A - Processo para a preparacao de n-formil-alfa-aspartil fenilalanina - Google Patents

Processo para a preparacao de n-formil-alfa-aspartil fenilalanina

Info

Publication number
BR8506312A
BR8506312A BR8506312A BR8506312A BR8506312A BR 8506312 A BR8506312 A BR 8506312A BR 8506312 A BR8506312 A BR 8506312A BR 8506312 A BR8506312 A BR 8506312A BR 8506312 A BR8506312 A BR 8506312A
Authority
BR
Brazil
Prior art keywords
asparty
formyl
phenylalanine
alpha
preparation
Prior art date
Application number
BR8506312A
Other languages
English (en)
Inventor
Ryuichi Mita
Toshio Katoh
Chojiro Higuchi
Takeshi Oura
Akihiro Yamaguchi
Original Assignee
Mitsui Toatsu Chemicals
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsui Toatsu Chemicals filed Critical Mitsui Toatsu Chemicals
Publication of BR8506312A publication Critical patent/BR8506312A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
    • C07K5/0613—Aspartame
BR8506312A 1984-12-17 1985-12-16 Processo para a preparacao de n-formil-alfa-aspartil fenilalanina BR8506312A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59264618A JPH07636B2 (ja) 1984-12-17 1984-12-17 Ｎ−ホルミル−α−アスパルチルフエニルアラニンの製造法

Publications (1)

Publication Number Publication Date
BR8506312A true BR8506312A (pt) 1986-08-26

Family

ID=17405832

Family Applications (1)

Application Number Title Priority Date Filing Date
BR8506312A BR8506312A (pt) 1984-12-17 1985-12-16 Processo para a preparacao de n-formil-alfa-aspartil fenilalanina

Country Status (12)

Country Link
US (1) US4745210A (pt)
EP (1) EP0186378B1 (pt)
JP (1) JPH07636B2 (pt)
KR (1) KR870000811B1 (pt)
AU (1) AU555831B2 (pt)
BR (1) BR8506312A (pt)
CA (1) CA1273749A (pt)
DE (1) DE3585219D1 (pt)
ES (1) ES8702435A1 (pt)
MX (1) MX162986B (pt)
NO (1) NO169126C (pt)
SU (1) SU1433414A3 (pt)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0680074B2 (ja) * 1985-07-01 1994-10-12 味の素株式会社 Ｎ―ホルミル―Ｌ―α―アスパルチル―Ｌ―フェニルアラニンの製法
DE3600731A1 (de) * 1986-01-13 1987-07-16 Green Cross Korea Verfahren zur herstellung von (alpha)-l-aspartyl-l-phenylalaninmethylester
JPH0696595B2 (ja) * 1986-05-07 1994-11-30 味の素株式会社 Ｎ−保護−Ｌ−α−アスパルチル−Ｌ−フエニルアラニンの製法
JPS6344594A (ja) * 1986-08-11 1988-02-25 Ajinomoto Co Inc Ｎ−保護−α−Ｌ−アスパルチル−Ｌ−フエニルアラニンの分離方法
DE3635582A1 (de) * 1986-10-20 1988-04-21 Hoechst Ag Verfahren zur reinigung von n-acyl-aspartam
US5053532A (en) * 1988-02-12 1991-10-01 The Nutra Sweet Company One-pot process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester hydrochloride
JPH089584B2 (ja) * 1988-02-12 1996-01-31 ザ ヌトラスウィート カンパニー α―Ｌ―アルパルチル―Ｌ―フェニルアラニンメチルエステル塩酸塩のワンポット製造法
US4946988A (en) * 1988-07-14 1990-08-07 The Nutrasweet Company Process for the preparation of α-L-aspartyl-L-phenylalanine methyl ester hydrochloride by use of isolated N-formyl L-aspartic anhydride
HU212897B (en) * 1990-03-12 1996-12-30 Nutrasweet Co Process for increasing the alpha/beta isomer ratio in asphartame coupling reaction
JPH05117246A (ja) * 1991-10-23 1993-05-14 Ajinomoto Co Inc 新規２，５−ジオキソピペラジン化合物とその製造法及びα−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル誘導体の製造法
EP1371633A1 (en) * 2002-06-14 2003-12-17 Bayer Ag Process for the purification of mixtures of toluenediisocyanate incorporating a dividing-wall distillation column
ES2271171T3 (es) * 2002-10-22 2007-04-16 Bayer Materialscience Ag Procedimiento para la purificacion de toluendiisocianato que incorpora una columna de destilacion de pared divisoria para la purificacion final.

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE791544A (fr) * 1971-11-19 1973-05-17 Stamicarbon Preparation d'esters alkyliques de dipeptide
JPS4896557A (pt) * 1972-03-22 1973-12-10
CA1028197A (en) * 1973-04-02 1978-03-21 Jeffrey H. Berg Concentrated liquid low calorie sweetener
US3933781A (en) * 1973-11-05 1976-01-20 Monsanto Company Process for the preparation of α-L-aspartyl-L-phenylalanine alkyl esters
JPS5140069A (pt) * 1974-10-02 1976-04-03 Hitachi Ltd
JPS5823380B2 (ja) * 1974-12-05 1983-05-14 味の素株式会社 ホルミルキノ ダツリホウ
JPS51113841A (en) * 1975-03-28 1976-10-07 Ajinomoto Co Inc Process for preparing lower alkyl esters of n-formyl-alpha -l-aspartyl-l-phenylalanine
JPS5223001A (en) * 1975-08-14 1977-02-21 Ajinomoto Co Inc Process for elimination of formyl group
MX4704E (es) * 1976-12-27 1982-08-04 Monsanto Co Procedimiento mejorado para la preparacion de ester metilico de alfa-l-aspartil-l-fenilalanina
JPS58185545A (ja) * 1982-04-22 1983-10-29 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステルまたはその塩酸塩の製法
GB2133409B (en) * 1983-01-13 1986-03-05 Erba Farmitalia Aspartame synthesis
GB8300810D0 (en) * 1983-01-13 1983-02-16 Erba Farmitalia Aspartame synthesis
JPS59219258A (ja) * 1983-05-28 1984-12-10 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法
JPH0613550B2 (ja) * 1983-06-03 1994-02-23 味の素株式会社 α―Ｌ―アスパルチル―Ｌ―フェニルアラニン―低級アルキルエステルの製造法
JPS59225152A (ja) * 1983-06-02 1984-12-18 Ajinomoto Co Inc α−Ｌ−アスパルチル−Ｌ−フエニルアラニンメチルエステル又はその塩酸塩の製法

Also Published As

Publication number Publication date
NO169126C (no) 1992-05-13
SU1433414A3 (ru) 1988-10-23
KR860004922A (ko) 1986-07-16
EP0186378A2 (en) 1986-07-02
NO855067L (no) 1986-06-18
KR870000811B1 (ko) 1987-04-20
JPH07636B2 (ja) 1995-01-11
AU5100385A (en) 1986-06-26
CA1273749A (en) 1990-09-04
JPS61143397A (ja) 1986-07-01
AU555831B2 (en) 1986-10-09
EP0186378B1 (en) 1992-01-15
US4745210A (en) 1988-05-17
NO169126B (no) 1992-02-03
ES8702435A1 (es) 1987-01-01
EP0186378A3 (en) 1988-07-27
ES549975A0 (es) 1987-01-01
MX162986B (es) 1991-07-30
DE3585219D1 (de) 1992-02-27

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Legal Events

Date Code Title Description
B15K Others concerning applications: alteration of classification

Ipc: C07K 5/075 (2006.01)