BR122018072594B8 - uso de uma composição farmacêutica - Google Patents

uso de uma composição farmacêutica

Info

Publication number
BR122018072594B8
BR122018072594B8 BR122018072594A BR122018072594A BR122018072594B8 BR 122018072594 B8 BR122018072594 B8 BR 122018072594B8 BR 122018072594 A BR122018072594 A BR 122018072594A BR 122018072594 A BR122018072594 A BR 122018072594A BR 122018072594 B8 BR122018072594 B8 BR 122018072594B8
Authority
BR
Brazil
Prior art keywords
pal
variants
pharmaceutical composition
compositions
prokaryotic
Prior art date
Application number
BR122018072594A
Other languages
English (en)
Portuguese (pt)
Other versions
BR122018072594B1 (pt
Inventor
O Okhamafe Augustus
J Wendt Daniel
D Kakkis Emil
C Vellard Michel
Muthalif Mubarack
A Fitzpatrick Paul
m bell Sean
Original Assignee
Biomarin Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40363135&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR122018072594(B8) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Biomarin Pharm Inc filed Critical Biomarin Pharm Inc
Publication of BR122018072594B1 publication Critical patent/BR122018072594B1/pt
Publication of BR122018072594B8 publication Critical patent/BR122018072594B8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/51—Lyases (4)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Diabetes (AREA)
  • Biomedical Technology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BR122018072594A 2007-08-17 2008-08-15 uso de uma composição farmacêutica BR122018072594B8 (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US6612507P 2007-08-17 2007-08-17
US61/066,125 2007-08-17
BRPI0811589A BRPI0811589B8 (pt) 2007-08-17 2008-08-15 composição farmacêutica, e, usos de uma composição farmacêutica
PCT/US2008/009765 WO2009025760A2 (en) 2007-08-17 2008-08-15 Compositions of prokaryotic phenylalanine ammonia-lyase and methods of treating cancer using compositions thereof

Publications (2)

Publication Number Publication Date
BR122018072594B1 BR122018072594B1 (pt) 2020-10-27
BR122018072594B8 true BR122018072594B8 (pt) 2021-07-27

Family

ID=40363135

Family Applications (2)

Application Number Title Priority Date Filing Date
BR122018072594A BR122018072594B8 (pt) 2007-08-17 2008-08-15 uso de uma composição farmacêutica
BRPI0811589A BRPI0811589B8 (pt) 2007-08-17 2008-08-15 composição farmacêutica, e, usos de uma composição farmacêutica

Family Applications After (1)

Application Number Title Priority Date Filing Date
BRPI0811589A BRPI0811589B8 (pt) 2007-08-17 2008-08-15 composição farmacêutica, e, usos de uma composição farmacêutica

Country Status (23)

Country Link
US (4) US7560263B2 (https=)
EP (1) EP2175875B1 (https=)
JP (1) JP5584120B2 (https=)
CN (1) CN101803492B (https=)
AR (2) AR067972A1 (https=)
AU (1) AU2008289549B2 (https=)
BR (2) BR122018072594B8 (https=)
CA (1) CA2687028C (https=)
CL (1) CL2008002390A1 (https=)
CY (1) CY1118222T1 (https=)
DK (1) DK2175875T3 (https=)
ES (1) ES2602618T3 (https=)
HR (1) HRP20161474T1 (https=)
HU (1) HUE029510T4 (https=)
LT (1) LT2175875T (https=)
MX (1) MX2009012261A (https=)
PE (1) PE20090605A1 (https=)
PL (1) PL2175875T3 (https=)
PT (1) PT2175875T (https=)
RU (2) RU2553343C2 (https=)
SI (1) SI2175875T1 (https=)
TW (1) TWI418787B (https=)
WO (1) WO2009025760A2 (https=)

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TW202016314A (zh) 2018-05-09 2020-05-01 美商拜奧馬林製藥公司 治療苯丙酮尿症之方法
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US10900055B2 (en) 2018-06-12 2021-01-26 Codexis, Inc. Engineered tyrosine ammonia lyase
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EP4501403A3 (en) 2019-08-30 2025-05-14 Société des Produits Nestlé S.A. Engineered lipase variants
JP2023507575A (ja) 2019-12-20 2023-02-24 コデクシス， インコーポレイテッド 操作された酸性アルファ－グルコシダーゼバリアント
JP2023512683A (ja) 2020-02-04 2023-03-28 コデクシス， インコーポレイテッド 操作されたロイシンデカルボキシラーゼ
TW202144575A (zh) 2020-04-03 2021-12-01 美商拜奧馬林製藥公司 使用ａａｖ及治療調配物之苯酮尿症治療
CN116897205A (zh) 2020-08-28 2023-10-17 科德克希思公司 工程化淀粉酶变体
AU2021334371A1 (en) 2020-08-28 2023-03-09 Codexis, Inc. Engineered protease variants
EP4341394A4 (en) 2021-05-19 2025-04-09 BioMarin Pharmaceutical Inc. Compositions of prokaryotic phenylalanine ammonia lyase and methods for treating adolescent patients
CA3220735A1 (en) 2021-05-21 2022-11-24 Codexis, Inc. Engineered methionine gamma lyase variants
JP2024540358A (ja) 2021-11-01 2024-10-31 シンティス バイオ，インコーポレイティド 工学操作ロイシン脱炭酸酵素
CN115873837A (zh) * 2022-11-18 2023-03-31 安徽盈科生物科技有限公司 高表达的新型的苯丙氨酸解氨酶
CN118931888A (zh) * 2023-05-09 2024-11-12 重庆派金生物科技有限公司 苯丙氨酸裂解酶突变体及其偶联物或其药学上可接受的盐
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US20250161466A1 (en) 2023-11-17 2025-05-22 Biomarin Pharmaceutical Inc. Conjugates of phenylalanine ammonia-lyase and poegma and methods for their use

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Also Published As

Publication number Publication date
PL2175875T3 (pl) 2017-04-28
US7790433B2 (en) 2010-09-07
SI2175875T1 (sl) 2017-01-31
US7537923B2 (en) 2009-05-26
HUE029510T4 (en) 2017-05-29
PT2175875T (pt) 2016-11-21
ES2602618T3 (es) 2017-02-21
HUE029510T2 (hu) 2017-02-28
CA2687028C (en) 2016-02-16
JP2010536759A (ja) 2010-12-02
AR117389A2 (es) 2021-08-04
TW200911283A (en) 2009-03-16
BR122018072594B1 (pt) 2020-10-27
RU2553343C2 (ru) 2015-06-10
WO2009025760A3 (en) 2009-06-25
CN101803492B (zh) 2014-05-07
EP2175875B1 (en) 2016-10-05
BRPI0811589B8 (pt) 2021-05-25
CN101803492A (zh) 2010-08-11
AU2008289549B2 (en) 2014-02-06
CY1118222T1 (el) 2017-06-28
US20090263369A1 (en) 2009-10-22
BRPI0811589B1 (pt) 2020-05-12
PE20090605A1 (es) 2009-05-16
HRP20161474T1 (hr) 2016-12-30
BRPI0811589A2 (pt) 2014-10-29
US7560263B2 (en) 2009-07-14
RU2009141987A (ru) 2011-05-20
AR067972A1 (es) 2009-10-28
AU2008289549A1 (en) 2009-02-26
US20100278802A1 (en) 2010-11-04
DK2175875T3 (en) 2016-11-21
WO2009025760A2 (en) 2009-02-26
TWI418787B (zh) 2013-12-11
EP2175875A2 (en) 2010-04-21
CL2008002390A1 (es) 2009-05-29
RU2012134838A (ru) 2014-03-20
JP5584120B2 (ja) 2014-09-03
MX2009012261A (es) 2010-03-15
US20090047265A1 (en) 2009-02-19
CA2687028A1 (en) 2009-02-26
LT2175875T (lt) 2016-12-12
US20090047268A1 (en) 2009-02-19

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