BR112022016774A2 - Síntese de vitamina k2 - Google Patents
Síntese de vitamina k2Info
- Publication number
- BR112022016774A2 BR112022016774A2 BR112022016774A BR112022016774A BR112022016774A2 BR 112022016774 A2 BR112022016774 A2 BR 112022016774A2 BR 112022016774 A BR112022016774 A BR 112022016774A BR 112022016774 A BR112022016774 A BR 112022016774A BR 112022016774 A2 BR112022016774 A2 BR 112022016774A2
- Authority
- BR
- Brazil
- Prior art keywords
- vitamin
- synthesis
- relates
- present
- new process
- Prior art date
Links
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 235000013343 vitamin Nutrition 0.000 title abstract 2
- 239000011782 vitamin Substances 0.000 title abstract 2
- 229940088594 vitamin Drugs 0.000 title abstract 2
- 229930003231 vitamin Natural products 0.000 title abstract 2
- 150000003722 vitamin derivatives Chemical class 0.000 title abstract 2
- DKHGMERMDICWDU-GHDNBGIDSA-N menaquinone-4 Chemical compound C1=CC=C2C(=O)C(C/C=C(C)/CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)=C(C)C(=O)C2=C1 DKHGMERMDICWDU-GHDNBGIDSA-N 0.000 abstract 2
- PFRQBZFETXBLTP-UHFFFAOYSA-N Vitamin K2 Natural products C1=CC=C2C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C(=O)C2=C1 PFRQBZFETXBLTP-UHFFFAOYSA-N 0.000 abstract 1
- 235000009491 menaquinone-4 Nutrition 0.000 abstract 1
- 239000011676 menaquinone-4 Substances 0.000 abstract 1
- 229960005481 menatetrenone Drugs 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 235000019143 vitamin K2 Nutrition 0.000 abstract 1
- 239000011728 vitamin K2 Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
- C07C67/28—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group
- C07C67/293—Preparation of carboxylic acid esters by modifying the hydroxylic moiety of the ester, such modification not being an introduction of an ester group by isomerisation; by change of size of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C46/00—Preparation of quinones
- C07C46/02—Preparation of quinones by oxidation giving rise to quinoid structures
- C07C46/06—Preparation of quinones by oxidation giving rise to quinoid structures of at least one hydroxy group on a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C50/00—Quinones
- C07C50/10—Quinones the quinoid structure being part of a condensed ring system containing two rings
- C07C50/14—Quinones the quinoid structure being part of a condensed ring system containing two rings with unsaturation outside the ring system, e.g. vitamin K1
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP20159175 | 2020-02-25 | ||
| PCT/EP2021/053706 WO2021170449A1 (en) | 2020-02-25 | 2021-02-16 | Vitamin k2 synthesis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022016774A2 true BR112022016774A2 (pt) | 2022-10-11 |
Family
ID=69740132
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022016774A BR112022016774A2 (pt) | 2020-02-25 | 2021-02-16 | Síntese de vitamina k2 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US12139456B2 (https=) |
| EP (1) | EP4110753A1 (https=) |
| JP (1) | JP2023514491A (https=) |
| CN (1) | CN115151524B (https=) |
| BR (1) | BR112022016774A2 (https=) |
| WO (1) | WO2021170449A1 (https=) |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB768650A (en) * | 1954-01-12 | 1957-02-20 | Merck & Co Inc | Vitamin k intermediates |
| DE3801743A1 (de) | 1987-07-03 | 1989-01-19 | Bayer Ag | Schaedlingsbekaempfungsmittel auf basis von substituierten 1,4-naphthochinonen und neue substituierte 1,4-naphthochinone |
| US6790463B2 (en) | 2001-03-30 | 2004-09-14 | Robert F. Hofmann | Uses of targeted oxidative therapeutic formulation in arteriosclerosis |
| CN100344621C (zh) | 2003-01-13 | 2007-10-24 | 帝斯曼知识产权资产管理有限公司 | α－生育酚乙酸酯的生产方法 |
| WO2005005407A1 (en) | 2003-07-08 | 2005-01-20 | Dsm Ip Assets B.V. | Manufacture of tocopherols using a bismuth catalyst |
| WO2007032378A1 (ja) * | 2005-09-15 | 2007-03-22 | Eisai R & D Management Co., Ltd. | キノン化合物の製造方法 |
| US7439402B2 (en) * | 2005-09-15 | 2008-10-21 | Eisai R&D Management Co., Ltd. | Method for producing quinone compound |
| WO2008099858A1 (ja) * | 2007-02-13 | 2008-08-21 | Kaneka Corporation | 硬化性組成物 |
| CN102351677B (zh) * | 2011-09-16 | 2014-04-09 | 重庆大学 | 一种化学合成维生素k2的方法 |
| JP6064264B2 (ja) | 2011-12-27 | 2017-01-25 | ディーエスエム アイピー アセッツ ビー．ブイ． | ビタミンａ中間体の触媒合成 |
| CN104513149A (zh) | 2013-09-29 | 2015-04-15 | 天津瑞安医药科技发展有限公司 | 四烯甲萘醌的合成方法 |
| CN104744230A (zh) | 2015-02-13 | 2015-07-01 | 安徽万和制药有限公司 | 一种合成维生素k1的方法 |
| CN105399615A (zh) | 2015-10-23 | 2016-03-16 | 山东广通宝医药有限公司 | 一种合成维生素k1的方法 |
-
2021
- 2021-02-16 US US17/801,681 patent/US12139456B2/en active Active
- 2021-02-16 BR BR112022016774A patent/BR112022016774A2/pt unknown
- 2021-02-16 CN CN202180016011.7A patent/CN115151524B/zh active Active
- 2021-02-16 JP JP2022543714A patent/JP2023514491A/ja active Pending
- 2021-02-16 EP EP21704811.5A patent/EP4110753A1/en active Pending
- 2021-02-16 WO PCT/EP2021/053706 patent/WO2021170449A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US12139456B2 (en) | 2024-11-12 |
| CN115151524A (zh) | 2022-10-04 |
| US20230159429A1 (en) | 2023-05-25 |
| CN115151524B (zh) | 2024-01-19 |
| WO2021170449A1 (en) | 2021-09-02 |
| JP2023514491A (ja) | 2023-04-06 |
| EP4110753A1 (en) | 2023-01-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B06W | Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette] |