BR112022000260A2 - Composição farmacêutica para entrega nasal - Google Patents
Composição farmacêutica para entrega nasalInfo
- Publication number
- BR112022000260A2 BR112022000260A2 BR112022000260A BR112022000260A BR112022000260A2 BR 112022000260 A2 BR112022000260 A2 BR 112022000260A2 BR 112022000260 A BR112022000260 A BR 112022000260A BR 112022000260 A BR112022000260 A BR 112022000260A BR 112022000260 A2 BR112022000260 A2 BR 112022000260A2
- Authority
- BR
- Brazil
- Prior art keywords
- pharmaceutical composition
- compositions
- nasal delivery
- applicators
- pharmaceutically acceptable
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/485—Morphinan derivatives, e.g. morphine, codeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1682—Processes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Addiction (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Psychiatry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16/506,023 US10653690B1 (en) | 2019-07-09 | 2019-07-09 | Pharmaceutical composition for nasal delivery |
| PCT/GB2020/051207 WO2021005325A1 (en) | 2019-07-09 | 2020-05-18 | Pharmaceutical composition for nasal delivery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112022000260A2 true BR112022000260A2 (pt) | 2022-03-03 |
Family
ID=70736393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112022000260A BR112022000260A2 (pt) | 2019-07-09 | 2020-05-18 | Composição farmacêutica para entrega nasal |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US10653690B1 (https=) |
| EP (1) | EP3996687A1 (https=) |
| JP (1) | JP7753183B2 (https=) |
| KR (1) | KR20220034153A (https=) |
| CN (1) | CN114096249B (https=) |
| AU (1) | AU2020311020B2 (https=) |
| BR (1) | BR112022000260A2 (https=) |
| CA (1) | CA3145965A1 (https=) |
| CL (1) | CL2022000033A1 (https=) |
| CO (1) | CO2022000254A2 (https=) |
| IL (1) | IL289513A (https=) |
| MX (1) | MX2022000368A (https=) |
| PE (1) | PE20220581A1 (https=) |
| PH (1) | PH12022550009A1 (https=) |
| WO (1) | WO2021005325A1 (https=) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2020245535B2 (en) | 2019-03-26 | 2022-06-30 | Pinova Therapeutics Inc. | Devices and methods for delivering pharmaceutical compositions |
| US10729687B1 (en) | 2019-07-09 | 2020-08-04 | Orexo Ab | Pharmaceutical composition for nasal delivery |
| FR3098407B1 (fr) * | 2019-07-10 | 2024-12-13 | Aptar France Sas | Dispositif de distribution nasale de poudre |
| CA3157364A1 (en) * | 2019-11-21 | 2021-05-27 | Phillip R. TORRALVA | Prophylaxis and reversal of stimulant and opioid/opiate overdose and/or toxic exposure |
| PT3962455T (pt) | 2020-05-18 | 2022-10-13 | Orexo Ab | Nova composição farmacêutica para entrega de fármacos |
| CA3207013A1 (en) * | 2021-02-01 | 2022-08-04 | Xinhua Li | Sequestration compounds for treatment of substance use disorder and uses thereof |
| US11278709B1 (en) | 2021-03-12 | 2022-03-22 | Pocket Naloxone Corp. | Drug delivery device and methods for using same |
| US12414916B2 (en) * | 2021-06-10 | 2025-09-16 | Belhaven BioPharma Inc. | Dry powder formulations of epinephrine and associated methods |
| US11617716B2 (en) * | 2021-06-10 | 2023-04-04 | Belhaven BioPharma Inc. | Dry powder formulations of epinephrine and associated methods |
| AR127783A1 (es) | 2021-11-25 | 2024-02-28 | Orexo Ab | Composición farmacéutica que comprende compuestos de drogas biofarmacéuticas |
| AR127780A1 (es) | 2021-11-25 | 2024-02-28 | Orexo Ab | Nueva composición farmacéutica que comprende adrenalina |
| GB202117016D0 (en) | 2021-11-25 | 2022-01-12 | Orexo Ab | New pharmaceutical device |
| GB202117015D0 (en) | 2021-11-25 | 2022-01-12 | Orexo Ab | New pharmaceutical composition |
| GB202117005D0 (en) | 2021-11-25 | 2022-01-12 | Orexo Ab | New pharmaceutical composition |
| GB202117007D0 (en) | 2021-11-25 | 2022-01-12 | Orexo Ab | New pharmaceutical composition |
| US12005185B2 (en) | 2021-12-17 | 2024-06-11 | Belhaven BioPharma Inc. | Medical counter measures including dry powder formulations and associated methods |
| GB202308123D0 (en) | 2023-05-31 | 2023-07-12 | Orexo Ab | New copmosition |
| TW202502309A (zh) | 2023-05-31 | 2025-01-16 | 瑞典商奥瑞克索股份公司 | 包含腎上腺素激導性受體調節劑的噴霧乾燥之組合物 |
| CN119326740A (zh) * | 2024-12-18 | 2025-01-21 | 纳索菲德(上海)制药技术有限公司 | 一种治疗生物节律失调的鼻脑递释制剂 |
Family Cites Families (62)
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| US5082669A (en) | 1989-07-20 | 1992-01-21 | Dainippon Pharmaceutical Co., Ltd. | Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked |
| SE8904296D0 (sv) | 1989-12-21 | 1989-12-21 | Pharmacia Ab | Transdermal system |
| ATE196427T1 (de) | 1993-12-06 | 2000-10-15 | Takeda Chemical Industries Ltd | Zusammensetzung mit verbesserter wasserlöslichkeit, enthaltend eine wasserunlösliche oder an wasser schwerunlösliche verbindung |
| DE19518810A1 (de) | 1995-05-26 | 1996-11-28 | Bayer Ag | Nasal-Applikator |
| CN1106888C (zh) | 1998-03-10 | 2003-04-30 | 瓦卢瓦股份有限公司 | 容器、容器的灌注方法及容器中流体制品的分配装置 |
| JP2000178184A (ja) | 1998-12-17 | 2000-06-27 | Lion Corp | 粒状組成物、錠剤及び粒状組成物の製造方法 |
| GB9908921D0 (en) | 1999-04-19 | 1999-06-16 | Britannia Pharmaceuticals Ltd | Spray dispenser for opiod antagonists |
| FR2817847B1 (fr) | 2000-12-08 | 2003-03-28 | Tebro | Dispositif de distribution de produit fluide ou pulverulent |
| ITMI20012174A1 (it) * | 2001-10-18 | 2003-04-18 | Univ Parma | Polvere per somministrazione nasale di farmaci |
| GB0201367D0 (en) | 2002-01-22 | 2002-03-13 | Ml Lab Plc | Composition |
| WO2004054511A2 (en) | 2002-12-13 | 2004-07-01 | The Regents Of The University Of California | Analgesic combination comprising nalbuphine |
| EP2343045A3 (en) * | 2003-02-24 | 2011-09-21 | Pharmaceutical Productions Inc. | Transmucosal drug delivery system |
| CN100471497C (zh) | 2003-06-25 | 2009-03-25 | 中国人民解放军军事医学科学院毒物药物研究所 | 盐酸纳洛酮鼻粉剂 |
| CN100515511C (zh) | 2003-10-09 | 2009-07-22 | 株式会社;生命科学活效 | 鼻腔用粉状药剂施药装置 |
| CN1640402A (zh) | 2004-01-02 | 2005-07-20 | 广东奇方药业有限公司 | 一种稳定的纳洛酮粉针剂 |
| IL159729A0 (en) | 2004-01-06 | 2004-06-20 | Doron I Friedman | Non-aqueous composition for oral delivery of insoluble bioactive agents |
| US9895444B2 (en) | 2004-08-25 | 2018-02-20 | Aegis Therapeutics, Llc | Compositions for drug administration |
| CN1305474C (zh) * | 2004-10-13 | 2007-03-21 | 北京国药龙立生物医药新技术有限公司 | 盐酸纳美芬鼻腔给药制剂 |
| CN1615867A (zh) | 2004-10-22 | 2005-05-18 | 北京阳光润禾科技有限公司 | 注射用盐酸纳洛酮冻干粉针制剂 |
| CN1781479B (zh) | 2004-12-02 | 2010-06-30 | 和记黄埔医药企业有限公司 | 一种马蔺子素分散体系及其制备方法 |
| US20080317863A1 (en) | 2005-02-10 | 2008-12-25 | Christer Nystrom | Pharmaceutical Compositions Useful in the Transmucosal Administration of Drugs |
| KR101233235B1 (ko) | 2005-08-26 | 2013-02-15 | 에스케이케미칼주식회사 | 초기 용출율이 개선된 프란루카스트 고체분산체의 약제학적조성물 및 그의 제조방법 |
| CN1939358A (zh) | 2005-09-30 | 2007-04-04 | 江西本草天工科技有限责任公司 | 肿节风分散片 |
| CN1813739A (zh) | 2005-11-25 | 2006-08-09 | 王颖 | 一种注射用盐酸纳美芬冻干粉针制剂 |
| PL2061427T3 (pl) | 2006-09-15 | 2011-12-30 | Echo Pharmaceuticals Bv | Granulat zawierający substancję farmaceutycznie aktywną i emulgator oraz sposób jego wytwarzania |
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| US20090246256A1 (en) | 2008-03-27 | 2009-10-01 | Al-Ghananeem Abeer M | Compositions and Methods for Transmucosal Delivery of Lofexidine |
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| EP2266563A1 (en) | 2009-06-11 | 2010-12-29 | Charité-Universitätsmedizin Berlin (Charité) | Use of opioid receptor antagonists for acute treatment of paraphilic arousal states |
| WO2011013003A2 (en) | 2009-07-31 | 2011-02-03 | Shin Nippon Biomedical Laboratories, Ltd. | Intranasal granisetron and nasal applicator |
| DK2480197T3 (en) | 2009-09-25 | 2016-01-25 | Reddys Lab Ltd Dr | Compositions containing triptanforbindelser |
| CN102068697B (zh) * | 2010-12-30 | 2013-10-16 | 宜昌人福药业有限责任公司 | 含有阿片类镇痛剂和阿片受体拮抗剂的药用组合物 |
| MY194947A (en) | 2011-05-13 | 2022-12-27 | Euro Celtique Sa | Intranasal pharmaceutical dosage forms comprising naloxone |
| EP3248642B1 (en) | 2012-06-28 | 2020-04-08 | The Government of The United States of America as represented by The Secretary of The Department of Health and Human Services | Nasal dry powder delivery system for vaccines and other treatment agents |
| FR3007992B1 (fr) | 2013-07-05 | 2018-01-26 | Aptar France Sas | Dispositif de distribution de produit fluide ou pulverulent. |
| WO2015095389A1 (en) | 2013-12-18 | 2015-06-25 | Aegis Therapeutics, Llc | Compositions for drug administration |
| CA2875384A1 (en) | 2013-12-20 | 2015-06-20 | AntiOP, Inc. | Intranasal naloxone compositions and methods of making and using same |
| US10085937B2 (en) | 2014-03-14 | 2018-10-02 | Adapt Pharma Limited | Nasal drug products and methods of their use |
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| US11135155B2 (en) | 2014-07-08 | 2021-10-05 | Hikma Pharmaceuticals Usa Inc. | Liquid naloxone spray |
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| EP3220893B1 (en) | 2014-11-14 | 2023-06-07 | Asoltech Srl | Composition based on coq10 |
| CN104547220A (zh) | 2014-12-30 | 2015-04-29 | 陈宏� | 一种治疗儿童视觉疲劳的中药组合物及其制剂 |
| US10166197B2 (en) * | 2015-02-13 | 2019-01-01 | St. John's University | Sugar ester nanoparticle stabilizers |
| BR112017014994B1 (pt) | 2015-02-17 | 2023-12-19 | Eli Lilly And Company | Composições em pó nasal para tratamento de hipoglicemia, seu uso e seus métodos de preparação, e aplicador nasal |
| AU2015390471A1 (en) | 2015-04-08 | 2017-11-09 | John KLASSEN | Pharmaceutical compositions of polyanionic and non-ionic cyclodextrin-based dendrimers and uses thereof |
| DK3400066T3 (da) * | 2016-01-08 | 2021-10-18 | Ohio State Innovation Foundation | Behandlinger og forebyggelse af neonatalt opioidt abstinenssyndrom |
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| KR102634829B1 (ko) | 2016-06-24 | 2024-02-07 | 오피언트 파마슈티컬스, 인코퍼레이티드 | 알코올 사용 장애의 치료용 조성물, 장치 및 방법 |
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| US20180092839A1 (en) | 2016-10-03 | 2018-04-05 | Lance L. Gooberman | Medicated spray for treatment of substance abuse, overdose, addiction and impulse control disorders |
| CA3043028A1 (en) | 2016-11-09 | 2018-05-17 | Opiant Pharmaceuticals, Inc. | Compositions, devices, and methods for the treatment of opioid-receptor-mediated conditions |
| IL312012A (en) | 2016-11-18 | 2024-06-01 | Opiant Pharmaceuticals Inc | Compositions and methods for the treatment of opioid overdose |
| CN106361700A (zh) * | 2016-11-25 | 2017-02-01 | 威海恒基伟业信息科技发展有限公司 | 盐酸纳美芬鼻腔给药制剂 |
| US10394770B2 (en) | 2016-12-30 | 2019-08-27 | General Electric Company | Methods and systems for implementing a data reconciliation framework |
| WO2018148382A1 (en) | 2017-02-10 | 2018-08-16 | Mucodel Pharma Llc | Chemically stable compositions of a pharmaceutical active agent in a multi-chambered delivery system for mucosal delivery |
| EP3668490A4 (en) | 2017-08-20 | 2021-06-09 | Formulex Pharma Innovations Ltd. | Dry powder compositions for intranasal delivery |
| US20180193332A1 (en) | 2017-10-09 | 2018-07-12 | Adapt Pharma Operations Limited | Low-temperature stable opioid antagonist solutions |
| CN109953952A (zh) * | 2017-12-25 | 2019-07-02 | 王旭宁 | 盐酸纳美芬鼻腔给药制剂 |
-
2019
- 2019-07-09 US US16/506,023 patent/US10653690B1/en active Active
-
2020
- 2020-05-18 EP EP20729147.7A patent/EP3996687A1/en active Pending
- 2020-05-18 BR BR112022000260A patent/BR112022000260A2/pt not_active Application Discontinuation
- 2020-05-18 AU AU2020311020A patent/AU2020311020B2/en active Active
- 2020-05-18 PE PE2022000019A patent/PE20220581A1/es unknown
- 2020-05-18 PH PH1/2022/550009A patent/PH12022550009A1/en unknown
- 2020-05-18 CN CN202080049503.1A patent/CN114096249B/zh active Active
- 2020-05-18 KR KR1020227003843A patent/KR20220034153A/ko active Pending
- 2020-05-18 JP JP2022501305A patent/JP7753183B2/ja active Active
- 2020-05-18 MX MX2022000368A patent/MX2022000368A/es unknown
- 2020-05-18 CA CA3145965A patent/CA3145965A1/en active Pending
- 2020-05-18 WO PCT/GB2020/051207 patent/WO2021005325A1/en not_active Ceased
-
2021
- 2021-12-30 IL IL289513A patent/IL289513A/en unknown
-
2022
- 2022-01-06 CL CL2022000033A patent/CL2022000033A1/es unknown
- 2022-01-14 CO CONC2022/0000254A patent/CO2022000254A2/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| WO2021005325A1 (en) | 2021-01-14 |
| IL289513A (en) | 2022-03-01 |
| MX2022000368A (es) | 2022-02-03 |
| CA3145965A1 (en) | 2021-01-14 |
| JP2022540227A (ja) | 2022-09-14 |
| CL2022000033A1 (es) | 2022-08-19 |
| US10653690B1 (en) | 2020-05-19 |
| CN114096249B (zh) | 2025-02-11 |
| AU2020311020A1 (en) | 2022-03-03 |
| PH12022550009A1 (en) | 2022-11-21 |
| JP7753183B2 (ja) | 2025-10-14 |
| PE20220581A1 (es) | 2022-04-20 |
| AU2020311020B2 (en) | 2026-03-05 |
| EP3996687A1 (en) | 2022-05-18 |
| CN114096249A (zh) | 2022-02-25 |
| CO2022000254A2 (es) | 2022-04-29 |
| KR20220034153A (ko) | 2022-03-17 |
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