JP7753183B2 - 経鼻送達用の医薬組成物 - Google Patents

経鼻送達用の医薬組成物

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Publication number
JP7753183B2
JP7753183B2 JP2022501305A JP2022501305A JP7753183B2 JP 7753183 B2 JP7753183 B2 JP 7753183B2 JP 2022501305 A JP2022501305 A JP 2022501305A JP 2022501305 A JP2022501305 A JP 2022501305A JP 7753183 B2 JP7753183 B2 JP 7753183B2
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JP
Japan
Prior art keywords
composition
compositions
present
opioid
weight
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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JP2022501305A
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English (en)
Japanese (ja)
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JP2022540227A (ja
JP2022540227A5 (https=
Inventor
ヨーナス・セヴマルケル
ローベルト・レン
アンドレアス・フィッシャー
Original Assignee
オレクソ・アクチエボラゲット
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Publication of JP2022540227A publication Critical patent/JP2022540227A/ja
Publication of JP2022540227A5 publication Critical patent/JP2022540227A5/ja
Application granted granted Critical
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Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/485—Morphinan derivatives, e.g. morphine, codeine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Addiction (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Otolaryngology (AREA)
  • Emergency Medicine (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2022501305A 2019-07-09 2020-05-18 経鼻送達用の医薬組成物 Active JP7753183B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16/506,023 2019-07-09
US16/506,023 US10653690B1 (en) 2019-07-09 2019-07-09 Pharmaceutical composition for nasal delivery
PCT/GB2020/051207 WO2021005325A1 (en) 2019-07-09 2020-05-18 Pharmaceutical composition for nasal delivery

Publications (3)

Publication Number Publication Date
JP2022540227A JP2022540227A (ja) 2022-09-14
JP2022540227A5 JP2022540227A5 (https=) 2023-06-14
JP7753183B2 true JP7753183B2 (ja) 2025-10-14

Family

ID=70736393

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2022501305A Active JP7753183B2 (ja) 2019-07-09 2020-05-18 経鼻送達用の医薬組成物

Country Status (15)

Country Link
US (1) US10653690B1 (https=)
EP (1) EP3996687A1 (https=)
JP (1) JP7753183B2 (https=)
KR (1) KR20220034153A (https=)
CN (1) CN114096249B (https=)
AU (1) AU2020311020B2 (https=)
BR (1) BR112022000260A2 (https=)
CA (1) CA3145965A1 (https=)
CL (1) CL2022000033A1 (https=)
CO (1) CO2022000254A2 (https=)
IL (1) IL289513A (https=)
MX (1) MX2022000368A (https=)
PE (1) PE20220581A1 (https=)
PH (1) PH12022550009A1 (https=)
WO (1) WO2021005325A1 (https=)

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PT3962455T (pt) 2020-05-18 2022-10-13 Orexo Ab Nova composição farmacêutica para entrega de fármacos
CA3207013A1 (en) * 2021-02-01 2022-08-04 Xinhua Li Sequestration compounds for treatment of substance use disorder and uses thereof
US11278709B1 (en) 2021-03-12 2022-03-22 Pocket Naloxone Corp. Drug delivery device and methods for using same
US12414916B2 (en) * 2021-06-10 2025-09-16 Belhaven BioPharma Inc. Dry powder formulations of epinephrine and associated methods
US11617716B2 (en) * 2021-06-10 2023-04-04 Belhaven BioPharma Inc. Dry powder formulations of epinephrine and associated methods
AR127783A1 (es) 2021-11-25 2024-02-28 Orexo Ab Composición farmacéutica que comprende compuestos de drogas biofarmacéuticas
AR127780A1 (es) 2021-11-25 2024-02-28 Orexo Ab Nueva composición farmacéutica que comprende adrenalina
GB202117016D0 (en) 2021-11-25 2022-01-12 Orexo Ab New pharmaceutical device
GB202117015D0 (en) 2021-11-25 2022-01-12 Orexo Ab New pharmaceutical composition
GB202117005D0 (en) 2021-11-25 2022-01-12 Orexo Ab New pharmaceutical composition
GB202117007D0 (en) 2021-11-25 2022-01-12 Orexo Ab New pharmaceutical composition
US12005185B2 (en) 2021-12-17 2024-06-11 Belhaven BioPharma Inc. Medical counter measures including dry powder formulations and associated methods
GB202308123D0 (en) 2023-05-31 2023-07-12 Orexo Ab New copmosition
TW202502309A (zh) 2023-05-31 2025-01-16 瑞典商奥瑞克索股份公司 包含腎上腺素激導性受體調節劑的噴霧乾燥之組合物
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Also Published As

Publication number Publication date
WO2021005325A1 (en) 2021-01-14
IL289513A (en) 2022-03-01
MX2022000368A (es) 2022-02-03
CA3145965A1 (en) 2021-01-14
JP2022540227A (ja) 2022-09-14
CL2022000033A1 (es) 2022-08-19
BR112022000260A2 (pt) 2022-03-03
US10653690B1 (en) 2020-05-19
CN114096249B (zh) 2025-02-11
AU2020311020A1 (en) 2022-03-03
PH12022550009A1 (en) 2022-11-21
PE20220581A1 (es) 2022-04-20
AU2020311020B2 (en) 2026-03-05
EP3996687A1 (en) 2022-05-18
CN114096249A (zh) 2022-02-25
CO2022000254A2 (es) 2022-04-29
KR20220034153A (ko) 2022-03-17

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