BR112021010789A2 - Anticorpos anti-il-36r para o tratamento de pustulose palmoplantar - Google Patents
Anticorpos anti-il-36r para o tratamento de pustulose palmoplantar Download PDFInfo
- Publication number
- BR112021010789A2 BR112021010789A2 BR112021010789-4A BR112021010789A BR112021010789A2 BR 112021010789 A2 BR112021010789 A2 BR 112021010789A2 BR 112021010789 A BR112021010789 A BR 112021010789A BR 112021010789 A2 BR112021010789 A2 BR 112021010789A2
- Authority
- BR
- Brazil
- Prior art keywords
- seq
- weeks
- amino acid
- ppp
- antibody
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Dermatology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201862785316P | 2018-12-27 | 2018-12-27 | |
| US62/785,316 | 2018-12-27 | ||
| US201962815431P | 2019-03-08 | 2019-03-08 | |
| US62/815,431 | 2019-03-08 | ||
| US201962891464P | 2019-08-26 | 2019-08-26 | |
| US62/891,464 | 2019-08-26 | ||
| PCT/EP2019/086521 WO2020136101A1 (en) | 2018-12-27 | 2019-12-20 | Anti-il-36r antibodies for treatment of palmoplantar pustulosis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112021010789A2 true BR112021010789A2 (pt) | 2021-08-31 |
Family
ID=69190739
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112021010789-4A BR112021010789A2 (pt) | 2018-12-27 | 2019-12-20 | Anticorpos anti-il-36r para o tratamento de pustulose palmoplantar |
Country Status (14)
| Country | Link |
|---|---|
| US (3) | US20200207862A1 (https=) |
| EP (1) | EP3902604A1 (https=) |
| JP (1) | JP2022515480A (https=) |
| KR (1) | KR20210119407A (https=) |
| CN (1) | CN113301955A (https=) |
| AU (1) | AU2019416727A1 (https=) |
| BR (1) | BR112021010789A2 (https=) |
| CA (1) | CA3124996A1 (https=) |
| CL (1) | CL2021001685A1 (https=) |
| IL (1) | IL284259A (https=) |
| MX (1) | MX2021007807A (https=) |
| PH (1) | PH12021551540A1 (https=) |
| TW (1) | TW202037604A (https=) |
| WO (1) | WO2020136101A1 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115925932A (zh) | 2015-04-15 | 2023-04-07 | 安奈普泰斯生物有限公司 | 针对白细胞介素36受体（il-36r）的抗体 |
| BR112020016738A2 (pt) | 2018-03-14 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Uso de anticorpos anti-il-36r para o tratamento de psoríase pustular generalizada |
| IL286100B2 (en) | 2019-03-08 | 2024-12-01 | Boehringer Ingelheim Int | Anti-il-36r antibody formulations |
| BR112022026999A2 (pt) * | 2020-07-17 | 2023-01-24 | Boehringer Ingelheim Int | Anticorpos anti-il-36r para tratamento de dermatoses neutrofílicas |
| EP4221839A1 (en) * | 2020-09-30 | 2023-08-09 | Boehringer Ingelheim International GmbH | Anti-il-36r antibodies for treatment of chronic inflammatory pain |
| CN112094349B (zh) * | 2020-11-04 | 2021-02-09 | 上海华奥泰生物药业股份有限公司 | 靶向于白介素36r的抗体及其制备方法和应用 |
| CA3209006A1 (en) * | 2021-03-04 | 2022-09-09 | Boehringer Ingelheim International Gmbh | Methods for the treatment of gpp |
| EP4334356A1 (en) * | 2021-05-03 | 2024-03-13 | Boehringer Ingelheim International Gmbh | Method for producing spesolimab |
| JP2024518536A (ja) * | 2021-05-12 | 2024-05-01 | アナプティスバイオ インコーポレイティッド | 抗体組成物 |
| EP4370550A1 (en) * | 2021-07-12 | 2024-05-22 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Use of il-36 inhibitors for the treatment of netherton syndrome |
| WO2024138141A2 (en) * | 2022-12-23 | 2024-06-27 | Icosavax, Inc. | Antibodies against metapneumovirus fusion (f) protein and uses thereof |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| WO2009040602A1 (en) | 2007-09-25 | 2009-04-02 | Becton Dickinson France | Autoinject0r with deactivating means moveable by a safety shield |
| SI3536710T1 (sl) | 2011-11-16 | 2026-04-30 | Boehringer Ingelheim International Gmbh | Protitelesa proti IL-36R |
| CH705992A2 (de) | 2012-10-11 | 2013-06-14 | Tecpharma Licensing Ag | Injektionsvorrichtung. |
| CN115925932A (zh) * | 2015-04-15 | 2023-04-07 | 安奈普泰斯生物有限公司 | 针对白细胞介素36受体（il-36r）的抗体 |
| CN112870489B (zh) | 2015-04-24 | 2022-12-06 | 艾斯曲尔医疗公司 | 药剂输送装置的子组件和药剂输送装置 |
| CH711066A2 (de) | 2015-05-13 | 2016-11-15 | Tecpharma Licensing Ag | Verbesserte Injektionsvorrichtung. |
| JP6654773B2 (ja) * | 2015-12-25 | 2020-02-26 | 国立大学法人名古屋大学 | インターロイキン３６受容体アンタゴニスト欠損症の治療薬 |
| BR112020016738A2 (pt) * | 2018-03-14 | 2020-12-15 | Boehringer Ingelheim International Gmbh | Uso de anticorpos anti-il-36r para o tratamento de psoríase pustular generalizada |
-
2019
- 2019-12-20 TW TW108147070A patent/TW202037604A/zh unknown
- 2019-12-20 JP JP2021537716A patent/JP2022515480A/ja active Pending
- 2019-12-20 AU AU2019416727A patent/AU2019416727A1/en not_active Abandoned
- 2019-12-20 US US16/722,133 patent/US20200207862A1/en not_active Abandoned
- 2019-12-20 MX MX2021007807A patent/MX2021007807A/es unknown
- 2019-12-20 CA CA3124996A patent/CA3124996A1/en active Pending
- 2019-12-20 BR BR112021010789-4A patent/BR112021010789A2/pt not_active Application Discontinuation
- 2019-12-20 KR KR1020217023769A patent/KR20210119407A/ko not_active Withdrawn
- 2019-12-20 EP EP19842584.5A patent/EP3902604A1/en active Pending
- 2019-12-20 WO PCT/EP2019/086521 patent/WO2020136101A1/en not_active Ceased
- 2019-12-20 CN CN201980087043.9A patent/CN113301955A/zh active Pending
-
2021
- 2021-06-21 IL IL284259A patent/IL284259A/en unknown
- 2021-06-23 CL CL2021001685A patent/CL2021001685A1/es unknown
- 2021-06-26 PH PH12021551540A patent/PH12021551540A1/en unknown
-
2022
- 2022-08-10 US US17/818,723 patent/US20230131364A1/en not_active Abandoned
- 2022-11-10 US US18/054,303 patent/US20230115617A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| CN113301955A (zh) | 2021-08-24 |
| PH12021551540A1 (en) | 2022-02-21 |
| EP3902604A1 (en) | 2021-11-03 |
| US20230131364A1 (en) | 2023-04-27 |
| TW202037604A (zh) | 2020-10-16 |
| AU2019416727A1 (en) | 2021-07-22 |
| US20230115617A1 (en) | 2023-04-13 |
| JP2022515480A (ja) | 2022-02-18 |
| IL284259A (en) | 2021-08-31 |
| CL2021001685A1 (es) | 2022-02-18 |
| US20200207862A1 (en) | 2020-07-02 |
| WO2020136101A1 (en) | 2020-07-02 |
| KR20210119407A (ko) | 2021-10-05 |
| CA3124996A1 (en) | 2020-07-02 |
| MX2021007807A (es) | 2021-08-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B11A | Dismissal acc. art.33 of ipl - examination not requested within 36 months of filing | ||
| B11Y | Definitive dismissal - extension of time limit for request of examination expired [chapter 11.1.1 patent gazette] |