IL284259A - Anti-IL-36R antibodies for the treatment of pustulosis in the hands and feet - Google Patents

Anti-IL-36R antibodies for the treatment of pustulosis in the hands and feet

Info

Publication number
IL284259A
IL284259A IL284259A IL28425921A IL284259A IL 284259 A IL284259 A IL 284259A IL 284259 A IL284259 A IL 284259A IL 28425921 A IL28425921 A IL 28425921A IL 284259 A IL284259 A IL 284259A
Authority
IL
Israel
Prior art keywords
antibodies
treatment
palmoplantar pustulosis
pustulosis
palmoplantar
Prior art date
Application number
IL284259A
Other languages
English (en)
Hebrew (he)
Original Assignee
Boehringer Ingelheim Int
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int filed Critical Boehringer Ingelheim Int
Publication of IL284259A publication Critical patent/IL284259A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
IL284259A 2018-12-27 2021-06-21 Anti-IL-36R antibodies for the treatment of pustulosis in the hands and feet IL284259A (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862785316P 2018-12-27 2018-12-27
US201962815431P 2019-03-08 2019-03-08
US201962891464P 2019-08-26 2019-08-26
PCT/EP2019/086521 WO2020136101A1 (en) 2018-12-27 2019-12-20 Anti-il-36r antibodies for treatment of palmoplantar pustulosis

Publications (1)

Publication Number Publication Date
IL284259A true IL284259A (en) 2021-08-31

Family

ID=69190739

Family Applications (1)

Application Number Title Priority Date Filing Date
IL284259A IL284259A (en) 2018-12-27 2021-06-21 Anti-IL-36R antibodies for the treatment of pustulosis in the hands and feet

Country Status (14)

Country Link
US (3) US20200207862A1 (https=)
EP (1) EP3902604A1 (https=)
JP (1) JP2022515480A (https=)
KR (1) KR20210119407A (https=)
CN (1) CN113301955A (https=)
AU (1) AU2019416727A1 (https=)
BR (1) BR112021010789A2 (https=)
CA (1) CA3124996A1 (https=)
CL (1) CL2021001685A1 (https=)
IL (1) IL284259A (https=)
MX (1) MX2021007807A (https=)
PH (1) PH12021551540A1 (https=)
TW (1) TW202037604A (https=)
WO (1) WO2020136101A1 (https=)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016168542A1 (en) 2015-04-15 2016-10-20 Anaptysbio, Inc. Antibodies directed against interleukin 36 receptor (il-36r)
CA3093692A1 (en) 2018-03-14 2019-09-19 Boehringer Ingelheim International Gmbh Use of anti-il-36r antibodies for treatment of generalized pustular psoriasis
BR112021016198A2 (pt) 2019-03-08 2021-11-03 Boehringer Ingelheim Int Formulações de anticorpo anti-il-36r
EP4182022A1 (en) * 2020-07-17 2023-05-24 Boehringer Ingelheim International GmbH Anti-il-36r antibodies for the treatment of neutrophilic dermatoses
US20220119538A1 (en) * 2020-09-30 2022-04-21 Boehringer Ingelheim International Gmbh Anti-il-36r antibodies for treatment of chronic inflammatory pain
CN112094349B (zh) * 2020-11-04 2021-02-09 上海华奥泰生物药业股份有限公司 靶向于白介素36r的抗体及其制备方法和应用
CA3209006A1 (en) * 2021-03-04 2022-09-09 Boehringer Ingelheim International Gmbh Methods for the treatment of gpp
BR112023017717A2 (pt) 2021-05-03 2024-01-09 Boehringer Ingelheim Int Método para produção de espesolimabe
CA3218343A1 (en) * 2021-05-12 2022-11-17 Anaptysbio, Inc. Antibody composition
EP4370550A1 (en) * 2021-07-12 2024-05-22 INSERM (Institut National de la Santé et de la Recherche Médicale) Use of il-36 inhibitors for the treatment of netherton syndrome
KR20250122528A (ko) * 2022-12-23 2025-08-13 아이코사백스, 인크. 메타뉴모바이러스 융합(f) 단백질에 대한 항체 및 그 용도

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
WO2009040602A1 (en) 2007-09-25 2009-04-02 Becton Dickinson France Autoinject0r with deactivating means moveable by a safety shield
KR102038310B1 (ko) 2011-11-16 2019-11-01 베링거 인겔하임 인터내셔날 게엠베하 항 il-36r 항체
CH705992A2 (de) 2012-10-11 2013-06-14 Tecpharma Licensing Ag Injektionsvorrichtung.
WO2016168542A1 (en) * 2015-04-15 2016-10-20 Anaptysbio, Inc. Antibodies directed against interleukin 36 receptor (il-36r)
CN107660155B (zh) 2015-04-24 2021-02-02 艾斯曲尔医疗公司 药剂输送装置的子组件和药剂输送装置
CH711066A2 (de) 2015-05-13 2016-11-15 Tecpharma Licensing Ag Verbesserte Injektionsvorrichtung.
JP6654773B2 (ja) * 2015-12-25 2020-02-26 国立大学法人名古屋大学 インターロイキン36受容体アンタゴニスト欠損症の治療薬
CA3093692A1 (en) * 2018-03-14 2019-09-19 Boehringer Ingelheim International Gmbh Use of anti-il-36r antibodies for treatment of generalized pustular psoriasis

Also Published As

Publication number Publication date
US20230131364A1 (en) 2023-04-27
TW202037604A (zh) 2020-10-16
MX2021007807A (es) 2021-08-11
JP2022515480A (ja) 2022-02-18
PH12021551540A1 (en) 2022-02-21
BR112021010789A2 (pt) 2021-08-31
WO2020136101A1 (en) 2020-07-02
EP3902604A1 (en) 2021-11-03
US20230115617A1 (en) 2023-04-13
CA3124996A1 (en) 2020-07-02
AU2019416727A1 (en) 2021-07-22
CN113301955A (zh) 2021-08-24
US20200207862A1 (en) 2020-07-02
CL2021001685A1 (es) 2022-02-18
KR20210119407A (ko) 2021-10-05

Similar Documents

Publication Publication Date Title
IL284259A (en) Anti-IL-36R antibodies for the treatment of pustulosis in the hands and feet
IL268479A (en) Anti-PD-1 antibodies for the treatment of lung cancer
IL264674B1 (en) Antibodies to siglec7 for cancer treatment
SG11202104923YA (en) Pharmaceutical combination for treatment of cancer
IL253462B2 (en) Cancer treatment with monoclonal antibodies against a latency-related peptide
ZA201708448B (en) Anti-cd38 antibodies for treatment of acute lymphoblastic leukemia
HUE053452T2 (hu) Anti-PD-1 és anti-LAG3 antitestek rák kezelésére
IL279260A (en) KDM1A inhibitors for the treatment of diseases
IL277861A (en) Antibodies specific to AXL for cancer treatment
GB201804514D0 (en) Treatment of pyroptosis
IL286000A (en) Asketamine for the treatment of depression
IL283948A (en) Methods for treating depression
IL256103B (en) Compositions and methods for treating celiac sprue disease
PL3742950T5 (pl) Urządzenie do obróbki podłóg
SG10202107832UA (en) Dosage regimen for treatment of solid tumors
IL269357A (en) Combination therapies for the treatment of breast cancer
IL270199A (en) Peptides for the treatment of diabetes
IL270716A (en) Combination of an erbb-2/erbb-3 bispecific antibody with endocrine therapy for breast cancer
PL3463328T3 (pl) Seladelpar do leczenia pierwotnego zapalenia dróg żółciowych
GB2577661B (en) Determination of lithography effective dose uniformity
GB201804515D0 (en) Treatment of necroptosis
EP3344287A4 (en) ANTI-SURVIVIN ANTIBODIES FOR CANCER THERAPY
IL282120A (en) Buprenorphine to treat respiratory depression
SG10201705433VA (en) X-Ray Back Scattering For Inspection Of Part
CA3265173A1 (en) Il-36r antibodies for treatment of palmoplantar pustulosis