BR112021001694A2 - polipeptídeos do receptor de antígeno quimérico em combinação com moléculas de metabolismo trans que modulam o ciclo de krebs e seus usos terapêuticos - Google Patents
polipeptídeos do receptor de antígeno quimérico em combinação com moléculas de metabolismo trans que modulam o ciclo de krebs e seus usos terapêuticos Download PDFInfo
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- BR112021001694A2 BR112021001694A2 BR112021001694-5A BR112021001694A BR112021001694A2 BR 112021001694 A2 BR112021001694 A2 BR 112021001694A2 BR 112021001694 A BR112021001694 A BR 112021001694A BR 112021001694 A2 BR112021001694 A2 BR 112021001694A2
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- C12N2740/14011—Deltaretrovirus, e.g. bovine leukeamia virus
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| PCT/US2019/046550 WO2020037066A1 (en) | 2018-08-14 | 2019-08-14 | Chimeric antigen receptor polypeptides in combination with trans metabolism molecules modulating krebs cycle and therapeutic uses thereof |
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| IL298999A (en) | 2020-06-11 | 2023-02-01 | Provention Bio Inc | Methods and compositions for the prevention of type 1 diabetes |
| AU2021292488A1 (en) * | 2020-06-15 | 2023-02-02 | Monopar Therapeutics, Inc. | Precision radioimmunotherapeutic targeting of the urokinase plasminogen activator receptor (uPAR) for treatment of severe COVID-19 disease |
| US20230265205A1 (en) * | 2020-08-10 | 2023-08-24 | Arizona Board Of Regents On Behalf Of Arizona State University | Metabolism-based chimeric antigen receptors and methods of treatment |
| JP2024520444A (ja) | 2021-05-24 | 2024-05-24 | プロヴェンション・バイオ・インコーポレイテッド | 1型糖尿病を治療するための方法 |
| WO2023049933A1 (en) | 2021-09-27 | 2023-03-30 | Sotio Biotech Inc. | Chimeric receptor polypeptides in combination with trans metabolism molecules that re-direct glucose metabolites out of the glycolysis pathway and therapeutic uses thereof |
| AU2022388928A1 (en) | 2021-11-16 | 2024-05-16 | Sotio Biotech Inc. | Treatment of myxoid/round cell liposarcoma patients |
| EP4249588A1 (en) * | 2022-03-22 | 2023-09-27 | Universität Basel Vizerektorat Forschung | Cellular therapy |
| WO2024015995A2 (en) * | 2022-07-15 | 2024-01-18 | Albert Einstein College Of Medicine | Chimeric antigen receptors comprising a tmigd2 costimulatory domain and associated methods of using the same |
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| WO2024040208A1 (en) | 2022-08-19 | 2024-02-22 | Sotio Biotech Inc. | Genetically engineered immune cells with chimeric receptor polypeptides in combination with multiple trans metabolism molecules and therapeutic uses thereof |
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