BR112021001044A2 - Compostos de sulfonimidamida como inibidores da atividade de interleucina-1 - Google Patents
Compostos de sulfonimidamida como inibidores da atividade de interleucina-1 Download PDFInfo
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- BR112021001044A2 BR112021001044A2 BR112021001044-0A BR112021001044A BR112021001044A2 BR 112021001044 A2 BR112021001044 A2 BR 112021001044A2 BR 112021001044 A BR112021001044 A BR 112021001044A BR 112021001044 A2 BR112021001044 A2 BR 112021001044A2
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- membered heteroaryl
- membered heterocyclyl
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Classifications
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- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
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- A61K31/5365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines ortho- or peri-condensed with heterocyclic ring systems
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- A61K31/553—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having at least one nitrogen and one oxygen as ring hetero atoms, e.g. loxapine, staurosporine
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D231/18—One oxygen or sulfur atom
- C07D231/20—One oxygen atom attached in position 3 or 5
- C07D231/22—One oxygen atom attached in position 3 or 5 with aryl radicals attached to ring nitrogen atoms
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
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- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
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- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
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- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
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| US20230202989A1 (en) | 2020-05-28 | 2023-06-29 | Janssen Pharmaceutica Nv | Compounds |
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2019
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- 2019-07-19 WO PCT/US2019/042711 patent/WO2020018975A1/en not_active Ceased
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- 2019-07-22 AR ARP190102055A patent/AR115822A1/es not_active Application Discontinuation
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2020
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| KR20210034596A (ko) | 2021-03-30 |
| AR115822A1 (es) | 2021-03-03 |
| SG11202013062VA (en) | 2021-02-25 |
| CR20210022A (es) | 2021-02-18 |
| JP7320595B2 (ja) | 2023-08-03 |
| TWI825134B (zh) | 2023-12-11 |
| PE20211811A1 (es) | 2021-09-14 |
| EP3823974A1 (en) | 2021-05-26 |
| AU2019306658A1 (en) | 2021-01-07 |
| CN112513048A (zh) | 2021-03-16 |
| MA53172A (fr) | 2021-05-26 |
| PH12021500005A1 (en) | 2021-09-13 |
| WO2020018975A1 (en) | 2020-01-23 |
| US12234245B2 (en) | 2025-02-25 |
| US20210253596A1 (en) | 2021-08-19 |
| US20250115618A1 (en) | 2025-04-10 |
| UA128558C2 (uk) | 2024-08-14 |
| CL2021000153A1 (es) | 2021-07-09 |
| IL279256A (en) | 2021-01-31 |
| MX2021000780A (es) | 2021-03-31 |
| TW202016078A (zh) | 2020-05-01 |
| CA3105521A1 (en) | 2020-01-23 |
| CO2021001530A2 (es) | 2021-03-08 |
| JP2021532101A (ja) | 2021-11-25 |
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