BR112019023246B1 - Compostos compreendendo uma fração quelante, métodos para produção dos mesmos e usos dos mesmos - Google Patents

Compostos compreendendo uma fração quelante, métodos para produção dos mesmos e usos dos mesmos Download PDF

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Publication number
BR112019023246B1
BR112019023246B1 BR112019023246-0A BR112019023246A BR112019023246B1 BR 112019023246 B1 BR112019023246 B1 BR 112019023246B1 BR 112019023246 A BR112019023246 A BR 112019023246A BR 112019023246 B1 BR112019023246 B1 BR 112019023246B1
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BR
Brazil
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alkyl
acid
group
optionally substituted
compound
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BR112019023246-0A
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English (en)
Portuguese (pt)
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BR112019023246A8 (pt
BR112019023246A2 (pt
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Eric Steven Burak
Stuart James Mahoney
Ryan Wayne Simms
John Fitzmaurice Valliant
Alla Darwish
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Centre For Probe Development And Commercialization
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Publication of BR112019023246A8 publication Critical patent/BR112019023246A8/pt
Publication of BR112019023246B1 publication Critical patent/BR112019023246B1/pt

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/0497Organic compounds conjugates with a carrier being an organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F5/00Compounds containing elements of Groups 3 or 13 of the Periodic Table
    • C07F5/003Compounds containing elements of Groups 3 or 13 of the Periodic Table without C-Metal linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/05Isotopically modified compounds, e.g. labelled

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BR112019023246-0A 2017-05-05 2018-05-04 Compostos compreendendo uma fração quelante, métodos para produção dos mesmos e usos dos mesmos BR112019023246B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762502260P 2017-05-05 2017-05-05
US62/502,260 2017-05-05
PCT/US2018/031228 WO2018204869A1 (en) 2017-05-05 2018-05-04 Pharmacokinetic enhancements of bifunctional chelates and uses thereof

Publications (3)

Publication Number Publication Date
BR112019023246A2 BR112019023246A2 (pt) 2020-05-19
BR112019023246A8 BR112019023246A8 (pt) 2021-02-23
BR112019023246B1 true BR112019023246B1 (pt) 2023-11-14

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Country Link
US (2) US11191854B2 (https=)
EP (1) EP3619191A4 (https=)
JP (2) JP7693317B2 (https=)
KR (1) KR102612882B1 (https=)
CN (2) CN111263747B (https=)
AU (3) AU2018261888B2 (https=)
BR (1) BR112019023246B1 (https=)
CA (1) CA3062553C (https=)
CL (1) CL2019003168A1 (https=)
EA (1) EA201992595A1 (https=)
IL (1) IL270453B2 (https=)
MA (1) MA48861A (https=)
RU (1) RU2019139432A (https=)
WO (1) WO2018204869A1 (https=)
ZA (1) ZA201908071B (https=)

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EP4190801A4 (en) * 2020-07-29 2024-10-02 Chugai Seiyaku Kabushiki Kaisha METHOD FOR MEASURING THE PHARMACOKINETICS OF A DRUG LABELED WITH A NON-RADIOACTIVE SUBSTANCE
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Publication number Publication date
CL2019003168A1 (es) 2020-08-28
RU2019139432A (ru) 2021-06-07
MA48861A (fr) 2020-04-01
AU2018261888B2 (en) 2022-06-30
JP7693317B2 (ja) 2025-06-17
JP2020518673A (ja) 2020-06-25
US11191854B2 (en) 2021-12-07
CN111263747B (zh) 2023-10-27
AU2022221451A1 (en) 2022-09-22
EP3619191A4 (en) 2020-12-16
WO2018204869A1 (en) 2018-11-08
EP3619191A1 (en) 2020-03-11
US20220054664A1 (en) 2022-02-24
BR112019023246A8 (pt) 2021-02-23
NZ759832A (en) 2025-05-30
CA3062553A1 (en) 2018-11-08
IL270453B1 (en) 2025-01-01
IL270453B2 (en) 2025-05-01
AU2018261888A1 (en) 2019-11-28
RU2019139432A3 (https=) 2021-06-16
BR112019023246A2 (pt) 2020-05-19
CN117603148A (zh) 2024-02-27
US20190030194A1 (en) 2019-01-31
ZA201908071B (en) 2023-04-26
KR102612882B1 (ko) 2023-12-11
IL270453A (https=) 2020-12-31
CN111263747A (zh) 2020-06-09
KR20200006087A (ko) 2020-01-17
EA201992595A1 (ru) 2020-04-21
CA3062553C (en) 2024-02-06
JP2023090748A (ja) 2023-06-29
AU2024227706A1 (en) 2024-11-21

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