BR112019020499B1 - Carboxamidas tricíclicas para controlar artrópodes, seus usos e seus intermediários, composição inseticida, e método para proteção de semente transgênica ou convencional - Google Patents

Carboxamidas tricíclicas para controlar artrópodes, seus usos e seus intermediários, composição inseticida, e método para proteção de semente transgênica ou convencional Download PDF

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Publication number
BR112019020499B1
BR112019020499B1 BR112019020499-7A BR112019020499A BR112019020499B1 BR 112019020499 B1 BR112019020499 B1 BR 112019020499B1 BR 112019020499 A BR112019020499 A BR 112019020499A BR 112019020499 B1 BR112019020499 B1 BR 112019020499B1
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BR
Brazil
Prior art keywords
spp
methyl
compounds
formula
pyrazol
Prior art date
Application number
BR112019020499-7A
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English (en)
Portuguese (pt)
Other versions
BR112019020499A2 (pt
Inventor
Tobias Harschneck
Alexander ARLT
Robert Velten
Michael Maue
Kerstin Ilg
Werner Hallenbach
Ulrich Görgens
Sebastian Horstmann
Peter Lösel
Andreas Turberg
Original Assignee
Bayer Cropscience Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Bayer Cropscience Aktiengesellschaft filed Critical Bayer Cropscience Aktiengesellschaft
Publication of BR112019020499A2 publication Critical patent/BR112019020499A2/pt
Publication of BR112019020499B1 publication Critical patent/BR112019020499B1/pt

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Classifications

    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N33/00Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds
    • A01N33/26Biocides, pest repellants or attractants, or plant growth regulators containing organic nitrogen compounds containing nitrogen-to-nitrogen bonds, e.g. azides, diazo-amino compounds, diazonium compounds, hydrazine derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/561,2-Diazoles; Hydrogenated 1,2-diazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/72Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
    • A01N43/74Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
    • A01N43/781,3-Thiazoles; Hydrogenated 1,3-thiazoles
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N53/00Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01PBIOCIDAL, PEST REPELLANT, PEST ATTRACTANT OR PLANT GROWTH REGULATORY ACTIVITY OF CHEMICAL COMPOUNDS OR PREPARATIONS
    • A01P7/00Arthropodicides
    • A01P7/04Insecticides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Insects & Arthropods (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
BR112019020499-7A 2017-03-31 2018-03-26 Carboxamidas tricíclicas para controlar artrópodes, seus usos e seus intermediários, composição inseticida, e método para proteção de semente transgênica ou convencional BR112019020499B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP17164442.0 2017-03-31
EP17164442 2017-03-31
PCT/EP2018/057614 WO2018177995A1 (de) 2017-03-31 2018-03-26 Trizyklische carboxamide zur bekämpfung von anthropoden

Publications (2)

Publication Number Publication Date
BR112019020499A2 BR112019020499A2 (pt) 2020-05-05
BR112019020499B1 true BR112019020499B1 (pt) 2023-12-05

Family

ID=58488868

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019020499-7A BR112019020499B1 (pt) 2017-03-31 2018-03-26 Carboxamidas tricíclicas para controlar artrópodes, seus usos e seus intermediários, composição inseticida, e método para proteção de semente transgênica ou convencional

Country Status (9)

Country Link
US (1) US11825838B2 (https=)
EP (2) EP4298908A3 (https=)
JP (1) JP7334118B2 (https=)
KR (1) KR20190134623A (https=)
CN (1) CN110475776B (https=)
AU (2) AU2018241748B2 (https=)
BR (1) BR112019020499B1 (https=)
ES (1) ES2967215T3 (https=)
WO (1) WO2018177995A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR112672A1 (es) * 2017-08-11 2019-11-27 Syngenta Participations Ag Derivados de tiofeno activos como plaguicidas
EP4183449A1 (en) * 2021-11-17 2023-05-24 Samsara Therapeutics Inc. Autophagy inducing compounds and uses thereof
CN114521553B (zh) * 2022-02-23 2023-04-25 福建省农业科学院植物保护研究所 一种用于防控榕属植物上虫瘿蓟马的专性拒食剂

Family Cites Families (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9816837D0 (en) 1998-08-04 1998-09-30 Zeneca Ltd Amide derivatives
JP4186484B2 (ja) 2002-03-12 2008-11-26 住友化学株式会社 ピリミジン化合物およびその用途
GB0213715D0 (en) 2002-06-14 2002-07-24 Syngenta Ltd Chemical compounds
US7217726B2 (en) 2002-08-22 2007-05-15 Orchid Chemicals & Pharmaceuticals Limited Antibacterial agents
TWI312272B (en) 2003-05-12 2009-07-21 Sumitomo Chemical Co Pyrimidine compound and pests controlling composition containing the same
AU2005219788B2 (en) 2004-03-05 2010-06-03 Nissan Chemical Corporation Isoxazoline-substituted benzamide compound and noxious organism control agent
GB0414438D0 (en) 2004-06-28 2004-07-28 Syngenta Participations Ag Chemical compounds
JP4970950B2 (ja) 2004-10-20 2012-07-11 クミアイ化学工業株式会社 3−トリアゾリルフェニルスルフィド誘導体及びそれを有効成分として含有する殺虫・殺ダニ・殺線虫剤
MX295245B (es) 2005-06-21 2012-01-26 Mitsui Chemicals Inc Derivado de amida e insecticida que contiene el mismo.
WO2008054702A1 (en) * 2006-10-31 2008-05-08 Schering Corporation Anilinopiperazine derivatives and methods of use thereof
WO2008074835A1 (en) 2006-12-20 2008-06-26 Novartis Ag 2-substituted 5-membered heterocycles as scd inhibitors
US8420690B2 (en) 2007-02-07 2013-04-16 Glaxosmithkline Llc Inhibitors of Akt activity
WO2008134969A1 (fr) 2007-04-30 2008-11-13 Sinochem Corporation Composés benzamides et leurs applications
GB0720126D0 (en) 2007-10-15 2007-11-28 Syngenta Participations Ag Chemical compounds
TWI411395B (zh) 2007-12-24 2013-10-11 Syngenta Participations Ag 殺蟲化合物
TWI401023B (zh) 2008-02-06 2013-07-11 Du Pont 中離子農藥
ES2372908T3 (es) 2008-02-25 2012-01-27 F. Hoffmann-La Roche Ag Inhibidores de la pirrolopirazina quinasa.
GB0804685D0 (en) 2008-03-13 2008-04-16 Univ Edinburgh Therapeutic compounds and their use
CN101337940B (zh) 2008-08-12 2012-05-02 国家农药创制工程技术研究中心 具杀虫活性的含氮杂环二氯烯丙醚类化合物
EP2184273A1 (de) 2008-11-05 2010-05-12 Bayer CropScience AG Halogen-substituierte Verbindungen als Pestizide
WO2010121675A2 (en) 2008-12-18 2010-10-28 F. Hoffmann-La Roche Ag Thiazolyl-benzimidazoles
WO2010093885A1 (en) 2009-02-12 2010-08-19 Glaxosmithkline Llc Inhibitors of akt activity
BR112012006956A2 (pt) * 2009-10-12 2015-09-15 Bayer Cropscience Ag 1- (pirida-3-il) -pirazóisol e 1- (pirimida-5-il) - pirazóisol como pesticidas
KR20130038842A (ko) 2010-03-18 2013-04-18 신젠타 파티서페이션즈 아게 살충성 화합물
WO2011149874A2 (en) 2010-05-26 2011-12-01 Schering Corporation N-phenyl imidazole carboxamide inhibitors of 3-phosphoinositide-dependent protein kinase-1
CA2803695A1 (en) * 2010-06-28 2012-01-05 Bayer Intellectual Property Gmbh Heteroaryl-substituted pyridine compounds for use as pesticides
WO2012002527A1 (ja) 2010-07-02 2012-01-05 あすか製薬株式会社 複素環化合物及びp27Kip1分解阻害剤
PH12013500237A1 (en) 2010-08-31 2013-03-11 Mitsui Chemicals Crop & Life Solutions Inc Pest control agent
US9006187B2 (en) 2010-09-10 2015-04-14 Green Cross Corporation Thiophene derivative as SGLT2 inhibitor and pharmaceutical composition comprising same
GB201015949D0 (en) 2010-09-22 2010-11-03 Medical Res Council Technology Compounds
FR2965262A1 (fr) 2010-09-24 2012-03-30 Sanofi Aventis Derives de nicotinamide, leur preparation et leur application en therapeutique
EP2632462A1 (en) * 2010-10-29 2013-09-04 Merck Sharp & Dohme Corp. Novel heteroaryl-carboxamide derivatives as pdk1 inhibitors
EP2643302A1 (en) 2010-11-23 2013-10-02 Syngenta Participations AG Insecticidal compounds
CN103261188A (zh) 2010-12-17 2013-08-21 先正达参股股份有限公司 杀虫化合物
CN102060818B (zh) 2011-01-07 2012-02-01 青岛科技大学 一种新型螺螨酯类化合物及其制法与用途
CN102057925B (zh) 2011-01-21 2013-04-10 陕西上格之路生物科学有限公司 一种含噻虫酰胺和生物源类杀虫剂的杀虫组合物
JPWO2012102387A1 (ja) * 2011-01-27 2014-07-03 日産化学工業株式会社 ピラゾール誘導体及び有害生物防除剤
BR112013020213A2 (pt) 2011-02-09 2016-08-02 Syngenta Participations Ag compostos inseticidas
EP2508511A1 (en) 2011-04-07 2012-10-10 Laboratoire Biodim Inhibitors of viral replication, their process of preparation and their therapeutical uses
WO2012175474A1 (en) 2011-06-20 2012-12-27 Syngenta Participations Ag 1,2,3 triazole pesticides
EP2800745B1 (en) 2011-12-02 2020-02-12 Phenex Pharmaceuticals AG Pyrrolo carboxamides as modulators of orphan nuclear receptor rar-related orphan receptor-gamma (rory, nr1f3) activity and for the treatment of chronic inflammatory and autoimmune diseases
ES2638144T3 (es) 2011-12-21 2017-10-18 Bayer Intellectual Property Gmbh Bencilpirazoles sustituidos
CN104202981B (zh) 2012-03-30 2018-01-30 巴斯夫欧洲公司 防治动物害虫的n‑取代的吡啶亚基化合物和衍生物
CN104968660A (zh) 2013-01-22 2015-10-07 霍夫曼-拉罗奇有限公司 作为bace1抑制剂的氟-[1,3]噁嗪类化合物
CN103232431B (zh) 2013-01-25 2014-11-05 青岛科技大学 一种二卤代吡唑酰胺类化合物及其应用
US9173401B2 (en) 2013-03-15 2015-11-03 Monsanto Technology Llc N-,C-disubstituted azoles and compositions and methods for controlling nematode pests
HRP20180791T1 (hr) 2013-07-25 2018-09-07 Janssen Sciences Ireland Uc Glioksamid supstituirani derivati pirolamida i njihova uporaba kao lijekova za liječenje hepatitisa b
AR100817A1 (es) * 2014-06-18 2016-11-02 Bayer Cropscience Ag Pirazoles y tetrazoles sustituidos con halógeno
JP2017521441A (ja) 2014-07-15 2017-08-03 バイエル・アニマル・ヘルス・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Animal Health Gmbh 有害生物防除剤としてのアリール−トリアゾリルピリジン類
WO2016055947A1 (en) 2014-10-07 2016-04-14 Glenmark Pharmaceuticals S.A. Alkyne compounds as s-nitrosoglutathione reductase inhibitors
UY36652A (es) 2015-04-30 2016-11-30 Bayer Animal Health Gmbh Combinaciones antiparasíticas
BR112018002867B1 (pt) 2015-08-13 2022-07-26 Bayer Cropscience Aktiengesellschaft Derivados de pirrol, diazol, triazol ou tetrazol, indicados para o controle de artrópodes
DE102016201878B3 (de) 2016-02-08 2017-08-03 Linde Aktiengesellschaft Vorrichtung zur zentralen Gasversorgung
US10544124B2 (en) * 2016-02-11 2020-01-28 Bayer Cropscience Aktiengesellschaft Substituted 2-(het)arylimidazolylcarboxyamides as pesticides
AR112672A1 (es) * 2017-08-11 2019-11-27 Syngenta Participations Ag Derivados de tiofeno activos como plaguicidas

Also Published As

Publication number Publication date
US11825838B2 (en) 2023-11-28
AU2018241748A1 (en) 2019-09-19
CN110475776B (zh) 2024-03-19
EP4298908A2 (de) 2024-01-03
AU2023202881A1 (en) 2023-05-25
EP3601279C0 (de) 2023-10-18
ES2967215T3 (es) 2024-05-24
JP7334118B2 (ja) 2023-08-28
CN110475776A (zh) 2019-11-19
US20210106005A1 (en) 2021-04-15
EP3601279B1 (de) 2023-10-18
BR112019020499A2 (pt) 2020-05-05
AU2023202881B2 (en) 2025-04-24
WO2018177995A1 (de) 2018-10-04
JP2020515562A (ja) 2020-05-28
KR20190134623A (ko) 2019-12-04
EP3601279A1 (de) 2020-02-05
AU2018241748B2 (en) 2023-02-09
EP4298908A3 (de) 2024-03-20

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B06W Patent application suspended after preliminary examination (for patents with searches from other patent authorities) chapter 6.23 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 26/03/2018, OBSERVADAS AS CONDICOES LEGAIS

B25A Requested transfer of rights approved

Owner name: BAYER ANIMAL HEALTH GMBH (DE)

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