BR112019005415A2 - nova vacina contra influenza suína - Google Patents
nova vacina contra influenza suínaInfo
- Publication number
- BR112019005415A2 BR112019005415A2 BR112019005415A BR112019005415A BR112019005415A2 BR 112019005415 A2 BR112019005415 A2 BR 112019005415A2 BR 112019005415 A BR112019005415 A BR 112019005415A BR 112019005415 A BR112019005415 A BR 112019005415A BR 112019005415 A2 BR112019005415 A2 BR 112019005415A2
- Authority
- BR
- Brazil
- Prior art keywords
- present
- sequence encoding
- food
- relates
- exogenous antigen
- Prior art date
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/145—Orthomyxoviridae, e.g. influenza virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5256—Virus expressing foreign proteins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/544—Mucosal route to the airways
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
- A61K2039/552—Veterinary vaccine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16041—Use of virus, viral particle or viral elements as a vector
- C12N2710/16043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16741—Use of virus, viral particle or viral elements as a vector
- C12N2710/16743—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16171—Demonstrated in vivo effect
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Pulmonology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
a presente invenção está relacionada, entre outros, a vetores de ehv que compreendem pelo menos uma (pelo menos duas) sequência que codifica um antígeno exógeno relacionado a um patógeno que infecta animais produtores de alimentos, a referida sequência que codifica um antígeno exógeno é inserida em um sítio de inserção (preferivelmente orf70) e a referida sequência que codifica um antígeno exógeno está ligada operacionalmente a uma sequência promotora (preferivelmente uma sequência promotora que compreende 4pgg600 (id. de seq. nº: 1) ou 4pmcp600 (id. de seq. nº: 2) ou as sequências de nucleotídeos complementares desta ou um fragmento funcional ou a funcional derivado destas ou as sequências de nucleotídeos complementares destas). além disso, a presente invenção está relacionada aos métodos para imunização de um animal produtor de alimentos que compreendem a administração a esse animal produtor de alimentos de uma composição imunogênica da presente invenção. além disso, a presente invenção está relacionada aos métodos para o tratamento ou profilaxia de sinais clínicos causados pelo vírus da influenza suína em um animal produtor de alimentos necessitado.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP16189767 | 2016-09-20 | ||
PCT/EP2017/073438 WO2018054822A1 (en) | 2016-09-20 | 2017-09-18 | New swine influenza vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
BR112019005415A2 true BR112019005415A2 (pt) | 2019-10-22 |
Family
ID=56979440
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112019005415A BR112019005415A2 (pt) | 2016-09-20 | 2017-09-18 | nova vacina contra influenza suína |
Country Status (16)
Country | Link |
---|---|
US (1) | US10626414B2 (pt) |
EP (1) | EP3515480A1 (pt) |
JP (1) | JP6951429B2 (pt) |
KR (1) | KR102566066B1 (pt) |
CN (1) | CN110072546B (pt) |
AR (1) | AR109538A1 (pt) |
AU (1) | AU2017329654B2 (pt) |
BR (1) | BR112019005415A2 (pt) |
CA (1) | CA3036310A1 (pt) |
CL (1) | CL2019000722A1 (pt) |
EA (1) | EA201990717A1 (pt) |
MX (1) | MX2019003116A (pt) |
PH (1) | PH12019500592A1 (pt) |
TW (1) | TW201823465A (pt) |
UY (1) | UY37408A (pt) |
WO (1) | WO2018054822A1 (pt) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP6952112B2 (ja) | 2016-09-20 | 2021-10-20 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH | 新規なehv挿入部位orf70 |
CN110072546B (zh) * | 2016-09-20 | 2023-10-31 | 勃林格殷格翰动物保健有限公司 | 新的猪流感疫苗 |
TWI780070B (zh) | 2016-09-20 | 2022-10-11 | 德商百靈佳殷格翰維美迪加股份有限公司 | 新穎之啟動子 |
CA3036386A1 (en) | 2016-09-20 | 2018-03-29 | Boehringer Ingelheim Vetmedica Gmbh | Canine adenovirus vectors |
EP3768326A1 (en) * | 2018-03-19 | 2021-01-27 | Boehringer Ingelheim Vetmedica GmbH | Ehv insertion site ul43 |
KR20210062015A (ko) * | 2018-09-20 | 2021-05-28 | 베링거잉겔하임베트메디카게엠베하 | 변형된 pedv 스파이크 단백질 |
US20230265130A1 (en) * | 2020-06-19 | 2023-08-24 | Intervet Inc. | Swine influenza a virus vaccine comprising a nucleic acid construct having a specific order of genes |
WO2022101679A1 (en) * | 2020-11-13 | 2022-05-19 | Boehringer Ingelheim Vetmedica Gmbh | New feline herpes virus vaccine |
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EP2759307B1 (en) | 2006-03-29 | 2016-11-09 | Merial Limited | Vaccine against Streptococci |
EP2062972A4 (en) | 2006-09-13 | 2010-11-24 | Nippon Zenyaku Kogyo Co Ltd | NEW DOG VACCINE |
WO2009120339A2 (en) | 2008-03-24 | 2009-10-01 | President And Fellows Of Harvard College | Vectors for delivering disease neutralizing agents |
SG188882A1 (en) | 2008-07-23 | 2013-04-30 | Boehringer Ingelheim Pharma | Novel regulatory elements |
US20130197612A1 (en) | 2010-02-26 | 2013-08-01 | Jack W. Lasersohn | Electromagnetic Radiation Therapy |
CN110072546B (zh) | 2016-09-20 | 2023-10-31 | 勃林格殷格翰动物保健有限公司 | 新的猪流感疫苗 |
JP6952112B2 (ja) | 2016-09-20 | 2021-10-20 | ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハーBoehringer Ingelheim Vetmedica GmbH | 新規なehv挿入部位orf70 |
TWI780070B (zh) | 2016-09-20 | 2022-10-11 | 德商百靈佳殷格翰維美迪加股份有限公司 | 新穎之啟動子 |
CA3036386A1 (en) | 2016-09-20 | 2018-03-29 | Boehringer Ingelheim Vetmedica Gmbh | Canine adenovirus vectors |
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2017
- 2017-09-18 CN CN201780057858.3A patent/CN110072546B/zh active Active
- 2017-09-18 BR BR112019005415A patent/BR112019005415A2/pt not_active Application Discontinuation
- 2017-09-18 EP EP17771405.2A patent/EP3515480A1/en active Pending
- 2017-09-18 EA EA201990717A patent/EA201990717A1/ru unknown
- 2017-09-18 AU AU2017329654A patent/AU2017329654B2/en active Active
- 2017-09-18 WO PCT/EP2017/073438 patent/WO2018054822A1/en unknown
- 2017-09-18 MX MX2019003116A patent/MX2019003116A/es unknown
- 2017-09-18 KR KR1020197011459A patent/KR102566066B1/ko active IP Right Grant
- 2017-09-18 UY UY0001037408A patent/UY37408A/es unknown
- 2017-09-18 CA CA3036310A patent/CA3036310A1/en active Pending
- 2017-09-18 JP JP2019515516A patent/JP6951429B2/ja active Active
- 2017-09-18 US US15/706,896 patent/US10626414B2/en active Active
- 2017-09-18 AR ARP170102575A patent/AR109538A1/es unknown
- 2017-09-18 TW TW106131992A patent/TW201823465A/zh unknown
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2019
- 2019-03-19 PH PH12019500592A patent/PH12019500592A1/en unknown
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KR20190054135A (ko) | 2019-05-21 |
TW201823465A (zh) | 2018-07-01 |
CN110072546B (zh) | 2023-10-31 |
AU2017329654B2 (en) | 2024-04-04 |
EP3515480A1 (en) | 2019-07-31 |
KR102566066B1 (ko) | 2023-08-16 |
JP2019531723A (ja) | 2019-11-07 |
CL2019000722A1 (es) | 2019-06-21 |
US10626414B2 (en) | 2020-04-21 |
US20180080044A1 (en) | 2018-03-22 |
CA3036310A1 (en) | 2018-03-29 |
CN110072546A (zh) | 2019-07-30 |
EA201990717A1 (ru) | 2019-10-31 |
UY37408A (es) | 2018-03-23 |
JP6951429B2 (ja) | 2021-10-20 |
AU2017329654A1 (en) | 2019-04-11 |
MX2019003116A (es) | 2019-08-29 |
WO2018054822A1 (en) | 2018-03-29 |
PH12019500592A1 (en) | 2020-01-20 |
AR109538A1 (es) | 2018-12-19 |
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