MX2019003116A - Nueva vacuna contra la gripe porcina. - Google Patents

Nueva vacuna contra la gripe porcina.

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Publication number
MX2019003116A
MX2019003116A MX2019003116A MX2019003116A MX2019003116A MX 2019003116 A MX2019003116 A MX 2019003116A MX 2019003116 A MX2019003116 A MX 2019003116A MX 2019003116 A MX2019003116 A MX 2019003116A MX 2019003116 A MX2019003116 A MX 2019003116A
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MX
Mexico
Prior art keywords
present
food producing
relates
exogenous antigen
encoding sequence
Prior art date
Application number
MX2019003116A
Other languages
English (en)
Inventor
Nikolin Veljko
Gallei Andreas
Mundt Alice
Original Assignee
Boehringer Ingelheim Vetmedica Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Vetmedica Gmbh filed Critical Boehringer Ingelheim Vetmedica Gmbh
Publication of MX2019003116A publication Critical patent/MX2019003116A/es

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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/145—Orthomyxoviridae, e.g. influenza virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61P37/02—Immunomodulators
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5256—Virus expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/544—Mucosal route to the airways
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K2039/70—Multivalent vaccine
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    • C12N2710/16011—Herpesviridae
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    • C12N2710/16011—Herpesviridae
    • C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
    • C12N2710/16741—Use of virus, viral particle or viral elements as a vector
    • C12N2710/16743—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
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    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
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    • C12N2760/00011—Details
    • C12N2760/16011—Orthomyxoviridae
    • C12N2760/16111—Influenzavirus A, i.e. influenza A virus
    • C12N2760/16171—Demonstrated in vivo effect

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Chemical & Material Sciences (AREA)
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  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
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  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La presente invención se refiere, entre otros, a vectores de EHV que comprenden al menos una (al menos dos) secuencia exógena que codifica un antígeno relacionada con un patógeno que infecta animales productores de alimentos, la secuencia exógena que codifica un antígeno se inserta en un sitio de inserción (preferentemente, ORF70), y la secuencia exógena que codifica un antígeno está ligada operativamente a una secuencia promotora (preferentemente, una secuencia promotora que comprende 4pgG600 (SEQ ID NO.: 1) o 4pMCP600 (SEQ ID NO.: 2), o la secuencia de nucleótidos complementaria de esta, o un fragmento funcional o un derivado funcional de aquella, o las secuencias de nucleótidos complementarias de aquellas). Asimismo, la presente invención se refiere a métodos para inmunizar un animal productor de alimentos, que comprenden administrar a dicho animal productor de alimentos una composición inmunógena de la presente invención. Además, la presente invención se refiere a métodos para el tratamiento o la profilaxis de signos clínicos causados por el virus de la gripe porcina en un animal productor de alimentos que lo necesita.
MX2019003116A 2016-09-20 2017-09-18 Nueva vacuna contra la gripe porcina. MX2019003116A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP16189767 2016-09-20
PCT/EP2017/073438 WO2018054822A1 (en) 2016-09-20 2017-09-18 New swine influenza vaccine

Publications (1)

Publication Number Publication Date
MX2019003116A true MX2019003116A (es) 2019-08-29

Family

ID=56979440

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2019003116A MX2019003116A (es) 2016-09-20 2017-09-18 Nueva vacuna contra la gripe porcina.

Country Status (16)

Country Link
US (1) US10626414B2 (es)
EP (1) EP3515480A1 (es)
JP (1) JP6951429B2 (es)
KR (1) KR102566066B1 (es)
CN (1) CN110072546B (es)
AR (1) AR109538A1 (es)
AU (1) AU2017329654B2 (es)
BR (1) BR112019005415A2 (es)
CA (1) CA3036310A1 (es)
CL (1) CL2019000722A1 (es)
EA (1) EA201990717A1 (es)
MX (1) MX2019003116A (es)
PH (1) PH12019500592A1 (es)
TW (1) TW201823465A (es)
UY (1) UY37408A (es)
WO (1) WO2018054822A1 (es)

Families Citing this family (7)

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KR102566066B1 (ko) * 2016-09-20 2023-08-16 베링거잉겔하임베트메디카게엠베하 신규한 돼지 인플루엔자 백신
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EP3768326A1 (en) * 2018-03-19 2021-01-27 Boehringer Ingelheim Vetmedica GmbH Ehv insertion site ul43
CN115768472A (zh) * 2020-06-19 2023-03-07 英特维特国际股份有限公司 包含具有特定基因顺序的核酸构建体的甲型猪流感病毒疫苗
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KR102566066B1 (ko) * 2016-09-20 2023-08-16 베링거잉겔하임베트메디카게엠베하 신규한 돼지 인플루엔자 백신

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KR20190054135A (ko) 2019-05-21
BR112019005415A2 (pt) 2019-10-22
WO2018054822A1 (en) 2018-03-29
CL2019000722A1 (es) 2019-06-21
AU2017329654B2 (en) 2024-04-04
AR109538A1 (es) 2018-12-19
UY37408A (es) 2018-03-23
US20180080044A1 (en) 2018-03-22
CA3036310A1 (en) 2018-03-29
JP6951429B2 (ja) 2021-10-20
KR102566066B1 (ko) 2023-08-16
US10626414B2 (en) 2020-04-21
EA201990717A1 (ru) 2019-10-31
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EP3515480A1 (en) 2019-07-31
CN110072546B (zh) 2023-10-31

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