BR112019003126A2 - método de tratamento ou prevenção de diarreia epidêmica suína, vacina e kit de vacinas - Google Patents

método de tratamento ou prevenção de diarreia epidêmica suína, vacina e kit de vacinas

Info

Publication number
BR112019003126A2
BR112019003126A2 BR112019003126A BR112019003126A BR112019003126A2 BR 112019003126 A2 BR112019003126 A2 BR 112019003126A2 BR 112019003126 A BR112019003126 A BR 112019003126A BR 112019003126 A BR112019003126 A BR 112019003126A BR 112019003126 A2 BR112019003126 A2 BR 112019003126A2
Authority
BR
Brazil
Prior art keywords
vaccine
epidemic diarrhea
swine epidemic
prevention
treatment
Prior art date
Application number
BR112019003126A
Other languages
English (en)
Inventor
Oroku Kazuki
Tsutsumi Nobuyuki
Sato Tetsuo
Furuya Yoshiaki
Ohshima Yoshiyuki
Original Assignee
Nippon Inst For Biological Science
Nisseiken Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Inst For Biological Science, Nisseiken Co Ltd filed Critical Nippon Inst For Biological Science
Publication of BR112019003126A2 publication Critical patent/BR112019003126A2/pt

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A61K39/225—Porcine transmissible gastroenteritis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A61K39/215—Coronaviridae, e.g. avian infectious bronchitis virus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0043—Nose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/543—Mucosal route intranasal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/545—Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Virology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Otolaryngology (AREA)
  • Dermatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

a presente invenção refere-se a um método para prevenir ou tratar a diarreia epidêmica suína, em que o método inclui: administrar uma vacina viva de vírus da diarreia epidêmica suína e um adjuvante a um porco via administração oral ou administração nasal; e administrar uma vacina inativada do vírus da diarreia epidêmica suína e um adjuvante ao porco via administração intramuscular.
BR112019003126A 2016-08-17 2017-07-24 método de tratamento ou prevenção de diarreia epidêmica suína, vacina e kit de vacinas BR112019003126A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016159797A JP6253210B1 (ja) 2016-08-17 2016-08-17 豚流行性下痢の予防又は治療方法、ワクチン、及びワクチンキット
PCT/JP2017/026692 WO2018034106A1 (ja) 2016-08-17 2017-07-24 豚流行性下痢の予防又は治療方法、ワクチン、及びワクチンキット

Publications (1)

Publication Number Publication Date
BR112019003126A2 true BR112019003126A2 (pt) 2019-07-09

Family

ID=60860075

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112019003126A BR112019003126A2 (pt) 2016-08-17 2017-07-24 método de tratamento ou prevenção de diarreia epidêmica suína, vacina e kit de vacinas

Country Status (12)

Country Link
US (1) US11013797B2 (pt)
EP (1) EP3501535B1 (pt)
JP (1) JP6253210B1 (pt)
KR (1) KR102439665B1 (pt)
BR (1) BR112019003126A2 (pt)
CA (1) CA3033730A1 (pt)
DK (1) DK3501535T3 (pt)
ES (1) ES2965854T3 (pt)
MX (1) MX2019001910A (pt)
PH (1) PH12019500330A1 (pt)
TW (1) TWI770041B (pt)
WO (1) WO2018034106A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11413347B2 (en) 2019-09-02 2022-08-16 Reber Genetics Co., Ltd. Vaccine composition and method of preventing porcine epidemic diarrhea virus infection in swine
CN111471658A (zh) * 2020-04-16 2020-07-31 武汉科前生物股份有限公司 一种病毒纯化方法及经由该方法制备得到的二联灭活疫苗
KR102484824B1 (ko) * 2020-09-03 2023-01-05 주식회사 중앙백신연구소 동물용 미끼백신 및 이의 제조방법
CN115074334B (zh) * 2021-03-15 2024-01-19 夏津新希望六和农牧有限公司 猪流行性腹泻病毒株、扩增培养方法、及其制备的疫苗组合物、制备方法和应用
CN113430177B (zh) * 2021-08-16 2022-09-02 山东信得科技股份有限公司 猪流行性腹泻病毒株、灭活疫苗、抗体及抗体的制备方法
CN116286679B (zh) * 2023-05-09 2023-08-01 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 一株经分离得到的猪流行性腹泻病毒变异株及其应用
CN116966290B (zh) * 2023-07-17 2024-05-28 浙江洪晟生物科技股份有限公司 猪流行性腹泻灭活疫苗制备方法及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10218788A (ja) * 1997-02-07 1998-08-18 Natl Fedelation Of Agricult Coop Assoc 免疫増強剤の製造法および免疫増強法
MXPA02012501A (es) * 2000-06-16 2003-06-06 Sembiosys Genetics Inc El uso de cuerpos grasos vegetales en sistemas de administracion de vacunas.
WO2004087204A2 (en) * 2003-04-04 2004-10-14 Pfizer Products Inc. Microfluidized oil-in-water emulsions and vaccine compositions
KR100622399B1 (ko) * 2004-01-14 2006-09-18 대한민국 불활화시킨 ｔｇｅｖ 및 ｐｅｄｖ을 함유하는 혼합불활화백신 및 그 제조방법
KR101442493B1 (ko) * 2014-02-21 2014-09-26 우진 비앤지 주식회사 돼지유행성설사병바이러스 약독화주 및 이를 포함하는 돼지유행성 설사병 백신 조성물
JP6395855B2 (ja) 2014-04-03 2018-09-26 ベーリンガー インゲルハイム フェトメディカ インコーポレイテッド ブタ流行性下痢ウイルスワクチン
WO2016007576A2 (en) * 2014-07-11 2016-01-14 Zoetis Services Llc Novel vaccine compositions for porcine epidemic diarrhea virus and porcine deltacoronavirus
CN104667269B (zh) * 2015-02-02 2018-01-09 广东海大畜牧兽医研究院有限公司 一种猪流行性腹泻病毒鼻腔免疫疫苗及其制备方法
KR101743142B1 (ko) * 2015-09-09 2017-06-02 강원대학교산학협력단 즉시 사용가능한 마이크로에멀젼 기반의 비강내 면역화용 면역보강제 조성물
KR101654023B1 (ko) * 2015-10-28 2016-09-06 우진 비앤지 주식회사 돼지유행성설사병바이러스 약독화주 및 불활화백신 조성물과 이를 이용한 경구 투여용 백신 조성물

Also Published As

Publication number Publication date
JP2018027903A (ja) 2018-02-22
KR20190039204A (ko) 2019-04-10
DK3501535T3 (da) 2024-01-02
TWI770041B (zh) 2022-07-11
EP3501535A1 (en) 2019-06-26
JP6253210B1 (ja) 2017-12-27
WO2018034106A1 (ja) 2018-02-22
CA3033730A1 (en) 2018-02-22
PH12019500330A1 (en) 2019-11-11
KR102439665B1 (ko) 2022-09-02
MX2019001910A (es) 2019-05-15
US11013797B2 (en) 2021-05-25
US20190209676A1 (en) 2019-07-11
ES2965854T3 (es) 2024-04-17
EP3501535B1 (en) 2023-09-20
EP3501535A4 (en) 2020-05-06
TW201825114A (zh) 2018-07-16

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