BR112018010679A8 - métodos para tratar, prevenir e diagnosticar a infecção por vírus da diarréia epidêmica porcina - Google Patents

métodos para tratar, prevenir e diagnosticar a infecção por vírus da diarréia epidêmica porcina

Info

Publication number
BR112018010679A8
BR112018010679A8 BR112018010679A BR112018010679A BR112018010679A8 BR 112018010679 A8 BR112018010679 A8 BR 112018010679A8 BR 112018010679 A BR112018010679 A BR 112018010679A BR 112018010679 A BR112018010679 A BR 112018010679A BR 112018010679 A8 BR112018010679 A8 BR 112018010679A8
Authority
BR
Brazil
Prior art keywords
methods
treating
preventing
virus infection
diarrhea virus
Prior art date
Application number
BR112018010679A
Other languages
English (en)
Other versions
BR112018010679A2 (pt
Inventor
Zakhartchouk Alexander
Potter Andrew
Allan Brenda
Van Den Hurk Jan
Tikoo Suresh
Gerdts Volker
Zhou Yan
Original Assignee
Univ Saskatchewan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Saskatchewan filed Critical Univ Saskatchewan
Publication of BR112018010679A2 publication Critical patent/BR112018010679A2/pt
Publication of BR112018010679A8 publication Critical patent/BR112018010679A8/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/12—Viral antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5252—Virus inactivated (killed)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/525—Virus
    • A61K2039/5254—Virus avirulent or attenuated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/55—Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552—Veterinary vaccine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55505—Inorganic adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • A61K2039/575—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 humoral response
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2770/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses positive-sense
    • C12N2770/00011—Details
    • C12N2770/20011—Coronaviridae
    • C12N2770/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/08—RNA viruses
    • G01N2333/165—Coronaviridae, e.g. avian infectious bronchitis virus
    • G01N2333/17—Porcine transmissible gastroenteritis virus

Abstract

a presente invenção se refere a imunógenos, composições e métodos para tratar, prevenir e/ou diagnosticar infecção por pedv em porcos. as composições e métodos usam vacinas contendo vírus inativado ou atenuado, ou vacinas de subunidade, incluindo imunógenos e misturas de imunógenos derivados de isolados de pedv.
BR112018010679A 2015-11-25 2016-11-24 métodos para tratar, prevenir e diagnosticar a infecção por vírus da diarréia epidêmica porcina BR112018010679A8 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562260128P 2015-11-25 2015-11-25
US201662382395P 2016-09-01 2016-09-01
PCT/CA2016/051381 WO2017088060A1 (en) 2015-11-25 2016-11-24 Methods for treating, preventing and diagnosing porcine epidemic diarrhea virus infection

Publications (2)

Publication Number Publication Date
BR112018010679A2 BR112018010679A2 (pt) 2018-11-13
BR112018010679A8 true BR112018010679A8 (pt) 2019-02-26

Family

ID=58762804

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018010679A BR112018010679A8 (pt) 2015-11-25 2016-11-24 métodos para tratar, prevenir e diagnosticar a infecção por vírus da diarréia epidêmica porcina

Country Status (9)

Country Link
US (1) US20180344836A1 (pt)
EP (1) EP3380494A4 (pt)
BR (1) BR112018010679A8 (pt)
CA (1) CA3004931A1 (pt)
HK (1) HK1259323A1 (pt)
MX (1) MX2018006416A (pt)
RU (1) RU2018123005A (pt)
TW (1) TW201731525A (pt)
WO (1) WO2017088060A1 (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108486067B (zh) * 2018-02-11 2022-03-15 黑龙江正康生物技术股份有限公司 猪流行性腹泻病毒变异株及其制备的灭活疫苗和应用
CN109337876A (zh) * 2018-10-15 2019-02-15 北京世纪元亨动物防疫技术有限公司 一种猪流行性腹泻病毒的纯化方法
US20220152185A1 (en) * 2019-02-28 2022-05-19 University Of Saskatchewan Lawsonia intracellularis compositions and methods of using the same
CN111474346B (zh) * 2020-04-15 2023-07-11 浙江理工大学绍兴生物医药研究院有限公司 猪流行性腹泻病毒IgA和IgG抗体检测试剂盒及其制备方法和应用
CN112415207B (zh) * 2020-10-27 2022-04-12 中国农业科学院兰州兽医研究所 一种基于抗猪流行性腹泻病毒变异毒株重组S2蛋白的IgA抗体ELISA检测试剂盒
CN115594760A (zh) * 2021-07-08 2023-01-13 刘扶东（Tw） 重组抗体及其用途

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010043039A1 (en) * 2008-10-16 2010-04-22 University Of Saskatchewan Combination adjuvant formulation
CN103675274B (zh) * 2013-12-17 2016-03-30 广西大学 检测猪流行性腹泻病毒抗体的间接elisa试剂盒
AU2015241107B2 (en) * 2014-04-03 2019-10-03 Boehringer Ingelheim Animal Health USA Inc. Porcine epidemic diarrhea virus vaccine
US9713639B2 (en) * 2014-05-19 2017-07-25 Merial, Inc. Recombinant spike protein subunit based vaccine for porcine epidemic diarrhea virus (PEDV)
PT3166634T (pt) * 2014-07-11 2021-09-29 Zoetis Services Llc Composições de vacina inovadoras para vírus da diarreia epidémica suína
CN104262488B (zh) * 2014-09-24 2017-07-28 普莱柯生物工程股份有限公司 一种融合蛋白及其疫苗组合物的制备与应用

Also Published As

Publication number Publication date
BR112018010679A2 (pt) 2018-11-13
EP3380494A1 (en) 2018-10-03
TW201731525A (zh) 2017-09-16
WO2017088060A1 (en) 2017-06-01
US20180344836A1 (en) 2018-12-06
CA3004931A1 (en) 2017-06-01
HK1259323A1 (zh) 2019-11-29
MX2018006416A (es) 2018-11-09
RU2018123005A (ru) 2019-12-25
RU2018123005A3 (pt) 2020-04-09
EP3380494A4 (en) 2019-11-13

Similar Documents

Publication Publication Date Title
BR112018010679A8 (pt) métodos para tratar, prevenir e diagnosticar a infecção por vírus da diarréia epidêmica porcina
MX2016012845A (es) Vacuna contra el virus de la diarrea epidemica porcina.
BR112018013387A2 (pt) vetor de vacinação recombinante, vírus mva, vacina ou composição farmacêutica e kit
MX2016016722A (es) Coronavirus.
PH12017501370A1 (en) Bivalent swine influenza virus vaccine
EA201692467A1 (ru) Вакцины против вируса гриппа и их применения
EA201692541A1 (ru) Вакцины против вируса гриппа и их применения
PH12018000197A1 (en) Hand, foot, and mouth vaccines and methods of manufacture and use thereof
BR112018075440A2 (pt) composições e métodos para prevenir e tratar a infecção por zika vírus
CO6551750A2 (es) Vacuna del virus del dengue inactivado que incluye un adyuvante sin aluminio
BR112019003126A2 (pt) método de tratamento ou prevenção de diarreia epidêmica suína, vacina e kit de vacinas
MY179251A (en) Methods and compositions for recombinant dengue viruses for vaccine and diagnostic development
EA201990010A1 (ru) Вакцина против вируса инфекционного бронхита
BR112017002440A2 (pt) vírus da diarreia epizoótica porcina mutante para utilização em uma vacina
BR112018074910A2 (pt) composição imunológica, e, método de indução de uma resposta imunológica contra o vírus da influenza equina em um sujeito
MX2019007252A (es) Metodos y composiciones para vacunas del virus del dengue.
BR112016015078A2 (pt) método para prevenir ou tratar infecção por vírus influenza a h7n9, uso do anticorpo e composição farmacêutica
PH12017550047B1 (en) Use of taurine in prevention and/or treatment of diseases induced by viruses of genus coronavirus and/or genus rotavirus
BR112016012393A2 (pt) Vacina, e, uso de uma combinação de um vírus prrs atenuado vivo e um antígeno de lawsonia intracellularis inativado
PH12018501750A1 (en) Porcine reproductive and respiratory syndrome vaccine virus
BR112017025316A2 (pt) estratégia de vacina baseada em nanopartículas contra o vírus da gripe suína
PH12017501943A1 (en) Influenza virus neutralizing peptidomimetic compounds
EA202090236A1 (ru) Иммуногенные композиции senecavirus a и способы с ними
MX2019013779A (es) Vacuna que comprende toxoides de clostridium.
BR112018007918A2 (pt) vacina, uso de antígeno de lawsonia intracellularis inativada, e, método para proteger um animal.

Legal Events

Date Code Title Description
B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 5A ANUIDADE.

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 DA RPI 2647 DE 28/09/2021.