BR112018075288A2 - métodos para diagnóstico de infecções bacterianas e virais - Google Patents
métodos para diagnóstico de infecções bacterianas e viraisInfo
- Publication number
- BR112018075288A2 BR112018075288A2 BR112018075288-6A BR112018075288A BR112018075288A2 BR 112018075288 A2 BR112018075288 A2 BR 112018075288A2 BR 112018075288 A BR112018075288 A BR 112018075288A BR 112018075288 A2 BR112018075288 A2 BR 112018075288A2
- Authority
- BR
- Brazil
- Prior art keywords
- methods
- viral infections
- diagnosing bacterial
- bacterial
- diagnosing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
- C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
- Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Medical Informatics (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Theoretical Computer Science (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662346962P | 2016-06-07 | 2016-06-07 | |
| US62/346,962 | 2016-06-07 | ||
| PCT/US2017/036003 WO2017214061A1 (en) | 2016-06-07 | 2017-06-05 | Methods for diagnosis of bacterial and viral infections |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BR112018075288A2 true BR112018075288A2 (pt) | 2019-03-19 |
Family
ID=60578903
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112018075288-6A BR112018075288A2 (pt) | 2016-06-07 | 2017-06-05 | métodos para diagnóstico de infecções bacterianas e virais |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US11274345B2 (https=) |
| EP (1) | EP3464645A4 (https=) |
| JP (2) | JP2019520042A (https=) |
| KR (3) | KR20230049750A (https=) |
| CN (1) | CN109312411A (https=) |
| AU (2) | AU2017278254A1 (https=) |
| BR (1) | BR112018075288A2 (https=) |
| CA (1) | CA3022616A1 (https=) |
| IL (2) | IL312537B2 (https=) |
| MX (2) | MX2018015184A (https=) |
| WO (1) | WO2017214061A1 (https=) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2019227186B2 (en) | 2018-02-27 | 2025-07-10 | The Board Of Trustees Of The Leland Stanford Junior University | Classifier for identification of robust sepsis subtypes |
| GB201806052D0 (en) | 2018-04-12 | 2018-05-30 | Univ Liverpool | Detection of bacterial infections |
| WO2019217296A1 (en) * | 2018-05-07 | 2019-11-14 | Yale University | Test to distinguish viral-only from bacterial infection or viral/bacterial coinfection using a respiratory swab |
| CN113195738B (zh) | 2018-08-04 | 2025-01-28 | 帝国理工学院创新有限公司 | 识别患有川崎病的受试者的方法 |
| CN112639122A (zh) * | 2018-09-19 | 2021-04-09 | 英芙勒玛提克斯公司 | 利用等温扩增和相对丰度评估宿主rna |
| US11369318B2 (en) | 2019-05-31 | 2022-06-28 | Light Ai, Inc. | Image processing of streptococcal infection in pharyngitis subjects |
| EP3864669B1 (en) | 2018-10-09 | 2024-12-04 | Light AI Inc. | Image processing of streptococcal infection in pharyngitis subjects |
| US20220267865A1 (en) * | 2019-02-05 | 2022-08-25 | Universidade De Santiago De Compostela | In vitro method for the diagnosis of viral infections |
| AU2020244763A1 (en) * | 2019-03-22 | 2021-09-30 | Inflammatix, Inc. | Systems and methods for deriving and optimizing classifiers from multiple datasets |
| WO2020197659A1 (en) | 2019-03-25 | 2020-10-01 | The Board Of Trustees Of The Leland Stanford Junior University | Signature for diagnosis of bacterial vs viral infections |
| US11104946B2 (en) * | 2019-04-23 | 2021-08-31 | Inflammatix, Inc. | DNA sequences related to diagnosis and treatment of systemic inflammatory response syndrome |
| CN110082338A (zh) * | 2019-05-15 | 2019-08-02 | 广西科技大学 | 超顺磁性Fe3O4@SiO2@Ag纳米复合材料用于对苯唑西林SERS检测的方法 |
| EP3817005A1 (en) * | 2019-11-01 | 2021-05-05 | Koninklijke Philips N.V. | System for infection diagnosis |
| AU2020382701A1 (en) * | 2019-11-13 | 2022-06-02 | The Regents Of The University Of Colorado A Body Corporate | Identification of host RNA biomarkers of infection |
| IL293728A (en) | 2019-12-11 | 2022-08-01 | Ichilov Tech Ltd | Non-invasive assay for differentiating between bacterial and viral infections |
| EP4629189A3 (en) | 2020-03-19 | 2025-12-24 | Light AI Inc. | Infection detection using image data analysis |
| WO2021192320A1 (ja) * | 2020-03-27 | 2021-09-30 | 株式会社島津製作所 | 新型コロナウイルスの検査方法および検査試薬 |
| KR102422238B1 (ko) * | 2020-04-27 | 2022-07-18 | 경북대학교 산학협력단 | TGFBIp의 아세틸화 수준을 측정하는 제제를 포함하는 중증급성호흡기증후군 바이러스 2 진단용 조성물 |
| WO2021221863A1 (en) * | 2020-04-28 | 2021-11-04 | Heeger, Brandon | Rapid testing mechanism and method for respiratory viral pathogens |
| CN111848772B (zh) * | 2020-08-03 | 2022-03-18 | 山东绿都生物科技有限公司 | SAMD9突变型蛋白、Vero细胞系及其构建方法和应用 |
| JP7748105B2 (ja) * | 2020-08-25 | 2025-10-02 | 学校法人 久留米大学 | ウイルス感染の判定方法 |
| EP4308729B1 (en) * | 2021-03-16 | 2025-10-29 | Cepheid | Methods for discriminating bacterial and viral infections in a human subject |
| WO2022235765A2 (en) * | 2021-05-04 | 2022-11-10 | Inflammatix, Inc. | Systems and methods for assessing a bacterial or viral status of a sample |
| CN115029426B (zh) * | 2022-04-19 | 2025-05-27 | 武汉大学中南医院 | 冠心病诊断剂及dysf基因甲基化在制备冠心病诊断剂中的应用 |
| EP4303326A1 (fr) * | 2022-07-06 | 2024-01-10 | Biomérieux | Determination du risque de deces d'un sujet infecte par un virus respiratoire par mesure du niveau d'expression du gene oas2 |
| EP4357778A1 (en) | 2022-10-20 | 2024-04-24 | Heraeus Medical GmbH | Treatment of microbial infections diagnosed using the biomarker d-lactate |
| WO2025059317A1 (en) * | 2023-09-13 | 2025-03-20 | President And Fellows Of Harvard College | Transcriptomic signatures for identifying drug-susceptible mycobacterium tuberculosis complex |
| KR102951592B1 (ko) | 2023-11-21 | 2026-04-14 | 바디텍메드(주) | 믹소바이러스 내성 단백질 a와 c-반응성 단백질을 이용한 박테리아감염과 바이러스감염 구별을 위한 진단 시스템 |
| CN118127149B (zh) * | 2024-05-10 | 2024-07-09 | 天津云检医学检验所有限公司 | 一种用于评估受试者的败血症风险和感染型的生物标志物、模型及试剂盒 |
| CN119479830B (zh) * | 2025-01-15 | 2025-05-16 | 北京大学 | 一种多中心数据聚合方法 |
| CN121380333B (zh) * | 2025-12-20 | 2026-04-21 | 广东辉锦创兴生物医学科技有限公司 | 通过检测宿主外周血基因表达鉴别待测样品感染类别的试剂盒及其方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040038201A1 (en) | 2002-01-22 | 2004-02-26 | Whitehead Institute For Biomedical Research | Diagnostic and therapeutic applications for biomarkers of infection |
| WO2007059119A2 (en) * | 2005-11-11 | 2007-05-24 | Ivan Borozan | Systems and methods for identifying diagnostic indicators |
| NZ573052A (en) | 2006-04-26 | 2012-03-30 | Vertex Pharma | Hepatitis c virus infection biomarkers |
| US9709565B2 (en) * | 2010-04-21 | 2017-07-18 | Memed Diagnostics Ltd. | Signatures and determinants for distinguishing between a bacterial and viral infection and methods of use thereof |
| WO2012012693A2 (en) * | 2010-07-23 | 2012-01-26 | President And Fellows Of Harvard College | Methods for detecting signatures of disease or conditions in bodily fluids |
| GB201201766D0 (en) * | 2012-02-01 | 2012-03-14 | Imp Innovations Ltd | Method |
| EP3367099B1 (en) * | 2012-02-09 | 2021-05-26 | Memed Diagnostics Ltd. | Signatures and determinants for diagnosing infections and methods of use thereof |
| WO2013162651A1 (en) | 2012-04-28 | 2013-10-31 | Us Army Center For Environmental Health Research(Cehr) | Biomarkers of immune dysfunction in response to chronic stress, methods of use and diagnostic kits |
| EP2847354A4 (en) * | 2012-05-08 | 2015-12-30 | Univ Leland Stanford Junior | METHOD AND COMPOSITIONS FOR ASSESSING A PRE-DECLAMPSY |
| CN109504768A (zh) * | 2013-03-15 | 2019-03-22 | 威拉赛特公司 | 用于诊断肺病的生物标记物及其使用方法 |
| US20160244834A1 (en) * | 2013-06-28 | 2016-08-25 | Acumen Research Laboratories Pte. Ltd. | Sepsis biomarkers and uses thereof |
| JP2016530545A (ja) * | 2013-09-17 | 2016-09-29 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | 卵巣がんに関するバイオマーカー |
| WO2015048098A1 (en) * | 2013-09-24 | 2015-04-02 | Washington University | Diagnostic methods for infectious disease using endogenous gene expression |
| GB201406259D0 (en) | 2014-04-07 | 2014-05-21 | Univ Edinburgh | Molecular predictors of neonatal sepsis |
| EP3221340B1 (en) * | 2014-11-19 | 2024-05-22 | P & M Venge AB | Diagnostic method employing human neutrophil lipocalin (hnl) |
-
2017
- 2017-06-05 AU AU2017278254A patent/AU2017278254A1/en not_active Abandoned
- 2017-06-05 KR KR1020237010265A patent/KR20230049750A/ko not_active Ceased
- 2017-06-05 MX MX2018015184A patent/MX2018015184A/es unknown
- 2017-06-05 CN CN201780035078.9A patent/CN109312411A/zh active Pending
- 2017-06-05 KR KR1020247021226A patent/KR102915694B1/ko active Active
- 2017-06-05 US US16/096,261 patent/US11274345B2/en active Active
- 2017-06-05 IL IL312537A patent/IL312537B2/en unknown
- 2017-06-05 JP JP2018556471A patent/JP2019520042A/ja not_active Ceased
- 2017-06-05 IL IL262762A patent/IL262762B2/en unknown
- 2017-06-05 BR BR112018075288-6A patent/BR112018075288A2/pt active Search and Examination
- 2017-06-05 WO PCT/US2017/036003 patent/WO2017214061A1/en not_active Ceased
- 2017-06-05 EP EP17810802.3A patent/EP3464645A4/en active Pending
- 2017-06-05 KR KR1020187035585A patent/KR102515555B1/ko active Active
- 2017-06-05 CA CA3022616A patent/CA3022616A1/en active Pending
-
2018
- 2018-12-06 MX MX2024009339A patent/MX2024009339A/es unknown
-
2022
- 2022-01-06 US US17/570,315 patent/US20220127673A1/en active Pending
-
2023
- 2023-04-05 JP JP2023061560A patent/JP7750895B2/ja active Active
- 2023-09-08 AU AU2023226757A patent/AU2023226757A1/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| MX2024009339A (es) | 2024-08-09 |
| KR20230049750A (ko) | 2023-04-13 |
| IL312537B2 (en) | 2026-01-01 |
| CA3022616A1 (en) | 2017-12-14 |
| JP2023098945A (ja) | 2023-07-11 |
| KR102915694B1 (ko) | 2026-01-20 |
| AU2017278254A1 (en) | 2018-11-15 |
| IL312537B1 (en) | 2025-09-01 |
| KR20190015294A (ko) | 2019-02-13 |
| IL262762A (en) | 2018-12-31 |
| IL262762B2 (en) | 2024-10-01 |
| EP3464645A4 (en) | 2020-05-06 |
| CN109312411A (zh) | 2019-02-05 |
| AU2023226757A1 (en) | 2023-09-28 |
| MX2018015184A (es) | 2019-04-24 |
| KR102515555B1 (ko) | 2023-03-28 |
| US20190144943A1 (en) | 2019-05-16 |
| EP3464645A1 (en) | 2019-04-10 |
| US20220127673A1 (en) | 2022-04-28 |
| IL312537A (en) | 2024-07-01 |
| KR20240100488A (ko) | 2024-07-01 |
| IL262762B1 (en) | 2024-06-01 |
| WO2017214061A1 (en) | 2017-12-14 |
| JP2019520042A (ja) | 2019-07-18 |
| JP7750895B2 (ja) | 2025-10-07 |
| US11274345B2 (en) | 2022-03-15 |
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