AU2017278254A1 - Methods for diagnosis of bacterial and viral infections - Google Patents

Methods for diagnosis of bacterial and viral infections Download PDF

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Publication number
AU2017278254A1
AU2017278254A1 AU2017278254A AU2017278254A AU2017278254A1 AU 2017278254 A1 AU2017278254 A1 AU 2017278254A1 AU 2017278254 A AU2017278254 A AU 2017278254A AU 2017278254 A AU2017278254 A AU 2017278254A AU 2017278254 A1 AU2017278254 A1 AU 2017278254A1
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AU
Australia
Prior art keywords
patient
biomarkers
viral
bacterial
response genes
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
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AU2017278254A
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English (en)
Inventor
Purvesh Khatri
Timothy E. Sweeney
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Leland Stanford Junior University
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Leland Stanford Junior University
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Publication date
Application filed by Leland Stanford Junior University filed Critical Leland Stanford Junior University
Publication of AU2017278254A1 publication Critical patent/AU2017278254A1/en
Priority to AU2023226757A priority Critical patent/AU2023226757A1/en
Abandoned legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56911—Bacteria
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
    • G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
    • G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A90/00—Technologies having an indirect contribution to adaptation to climate change
    • Y02A90/10—Information and communication technologies [ICT] supporting adaptation to climate change, e.g. for weather forecasting or climate simulation

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Virology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • Medical Informatics (AREA)
  • Evolutionary Biology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Theoretical Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU2017278254A 2016-06-07 2017-06-05 Methods for diagnosis of bacterial and viral infections Abandoned AU2017278254A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2023226757A AU2023226757A1 (en) 2016-06-07 2023-09-08 Methods for diagnosis of bacterial and viral infections

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201662346962P 2016-06-07 2016-06-07
US62/346,962 2016-06-07
PCT/US2017/036003 WO2017214061A1 (en) 2016-06-07 2017-06-05 Methods for diagnosis of bacterial and viral infections

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2023226757A Division AU2023226757A1 (en) 2016-06-07 2023-09-08 Methods for diagnosis of bacterial and viral infections

Publications (1)

Publication Number Publication Date
AU2017278254A1 true AU2017278254A1 (en) 2018-11-15

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Family Applications (2)

Application Number Title Priority Date Filing Date
AU2017278254A Abandoned AU2017278254A1 (en) 2016-06-07 2017-06-05 Methods for diagnosis of bacterial and viral infections
AU2023226757A Pending AU2023226757A1 (en) 2016-06-07 2023-09-08 Methods for diagnosis of bacterial and viral infections

Family Applications After (1)

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AU2023226757A Pending AU2023226757A1 (en) 2016-06-07 2023-09-08 Methods for diagnosis of bacterial and viral infections

Country Status (11)

Country Link
US (2) US11274345B2 (https=)
EP (1) EP3464645A4 (https=)
JP (2) JP2019520042A (https=)
KR (3) KR20230049750A (https=)
CN (1) CN109312411A (https=)
AU (2) AU2017278254A1 (https=)
BR (1) BR112018075288A2 (https=)
CA (1) CA3022616A1 (https=)
IL (2) IL312537B2 (https=)
MX (2) MX2018015184A (https=)
WO (1) WO2017214061A1 (https=)

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WO2019217296A1 (en) * 2018-05-07 2019-11-14 Yale University Test to distinguish viral-only from bacterial infection or viral/bacterial coinfection using a respiratory swab
CN113195738B (zh) 2018-08-04 2025-01-28 帝国理工学院创新有限公司 识别患有川崎病的受试者的方法
CN112639122A (zh) * 2018-09-19 2021-04-09 英芙勒玛提克斯公司 利用等温扩增和相对丰度评估宿主rna
US11369318B2 (en) 2019-05-31 2022-06-28 Light Ai, Inc. Image processing of streptococcal infection in pharyngitis subjects
EP3864669B1 (en) 2018-10-09 2024-12-04 Light AI Inc. Image processing of streptococcal infection in pharyngitis subjects
US20220267865A1 (en) * 2019-02-05 2022-08-25 Universidade De Santiago De Compostela In vitro method for the diagnosis of viral infections
AU2020244763A1 (en) * 2019-03-22 2021-09-30 Inflammatix, Inc. Systems and methods for deriving and optimizing classifiers from multiple datasets
WO2020197659A1 (en) 2019-03-25 2020-10-01 The Board Of Trustees Of The Leland Stanford Junior University Signature for diagnosis of bacterial vs viral infections
US11104946B2 (en) * 2019-04-23 2021-08-31 Inflammatix, Inc. DNA sequences related to diagnosis and treatment of systemic inflammatory response syndrome
CN110082338A (zh) * 2019-05-15 2019-08-02 广西科技大学 超顺磁性Fe3O4@SiO2@Ag纳米复合材料用于对苯唑西林SERS检测的方法
EP3817005A1 (en) * 2019-11-01 2021-05-05 Koninklijke Philips N.V. System for infection diagnosis
AU2020382701A1 (en) * 2019-11-13 2022-06-02 The Regents Of The University Of Colorado A Body Corporate Identification of host RNA biomarkers of infection
IL293728A (en) 2019-12-11 2022-08-01 Ichilov Tech Ltd Non-invasive assay for differentiating between bacterial and viral infections
EP4629189A3 (en) 2020-03-19 2025-12-24 Light AI Inc. Infection detection using image data analysis
WO2021192320A1 (ja) * 2020-03-27 2021-09-30 株式会社島津製作所 新型コロナウイルスの検査方法および検査試薬
KR102422238B1 (ko) * 2020-04-27 2022-07-18 경북대학교 산학협력단 TGFBIp의 아세틸화 수준을 측정하는 제제를 포함하는 중증급성호흡기증후군 바이러스 2 진단용 조성물
WO2021221863A1 (en) * 2020-04-28 2021-11-04 Heeger, Brandon Rapid testing mechanism and method for respiratory viral pathogens
CN111848772B (zh) * 2020-08-03 2022-03-18 山东绿都生物科技有限公司 SAMD9突变型蛋白、Vero细胞系及其构建方法和应用
JP7748105B2 (ja) * 2020-08-25 2025-10-02 学校法人 久留米大学 ウイルス感染の判定方法
EP4308729B1 (en) * 2021-03-16 2025-10-29 Cepheid Methods for discriminating bacterial and viral infections in a human subject
WO2022235765A2 (en) * 2021-05-04 2022-11-10 Inflammatix, Inc. Systems and methods for assessing a bacterial or viral status of a sample
CN115029426B (zh) * 2022-04-19 2025-05-27 武汉大学中南医院 冠心病诊断剂及dysf基因甲基化在制备冠心病诊断剂中的应用
EP4303326A1 (fr) * 2022-07-06 2024-01-10 Biomérieux Determination du risque de deces d'un sujet infecte par un virus respiratoire par mesure du niveau d'expression du gene oas2
EP4357778A1 (en) 2022-10-20 2024-04-24 Heraeus Medical GmbH Treatment of microbial infections diagnosed using the biomarker d-lactate
WO2025059317A1 (en) * 2023-09-13 2025-03-20 President And Fellows Of Harvard College Transcriptomic signatures for identifying drug-susceptible mycobacterium tuberculosis complex
KR102951592B1 (ko) 2023-11-21 2026-04-14 바디텍메드(주) 믹소바이러스 내성 단백질 a와 c-반응성 단백질을 이용한 박테리아감염과 바이러스감염 구별을 위한 진단 시스템
CN118127149B (zh) * 2024-05-10 2024-07-09 天津云检医学检验所有限公司 一种用于评估受试者的败血症风险和感染型的生物标志物、模型及试剂盒
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Also Published As

Publication number Publication date
MX2024009339A (es) 2024-08-09
KR20230049750A (ko) 2023-04-13
IL312537B2 (en) 2026-01-01
CA3022616A1 (en) 2017-12-14
JP2023098945A (ja) 2023-07-11
KR102915694B1 (ko) 2026-01-20
IL312537B1 (en) 2025-09-01
KR20190015294A (ko) 2019-02-13
BR112018075288A2 (pt) 2019-03-19
IL262762A (en) 2018-12-31
IL262762B2 (en) 2024-10-01
EP3464645A4 (en) 2020-05-06
CN109312411A (zh) 2019-02-05
AU2023226757A1 (en) 2023-09-28
MX2018015184A (es) 2019-04-24
KR102515555B1 (ko) 2023-03-28
US20190144943A1 (en) 2019-05-16
EP3464645A1 (en) 2019-04-10
US20220127673A1 (en) 2022-04-28
IL312537A (en) 2024-07-01
KR20240100488A (ko) 2024-07-01
IL262762B1 (en) 2024-06-01
WO2017214061A1 (en) 2017-12-14
JP2019520042A (ja) 2019-07-18
JP7750895B2 (ja) 2025-10-07
US11274345B2 (en) 2022-03-15

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