BR112018012223A2 - membrana de camada única, métodos de fabrico de uma membrana e de preparação de um tecido biológico reconstruído, dispositivo de cultura celular, utilização in vitro da membrana, tecido biológico reconstruído e utilização de um tecido biológico reconstruído - Google Patents

membrana de camada única, métodos de fabrico de uma membrana e de preparação de um tecido biológico reconstruído, dispositivo de cultura celular, utilização in vitro da membrana, tecido biológico reconstruído e utilização de um tecido biológico reconstruído

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Publication number
BR112018012223A2
BR112018012223A2 BR112018012223-8A BR112018012223A BR112018012223A2 BR 112018012223 A2 BR112018012223 A2 BR 112018012223A2 BR 112018012223 A BR112018012223 A BR 112018012223A BR 112018012223 A2 BR112018012223 A2 BR 112018012223A2
Authority
BR
Brazil
Prior art keywords
biological tissue
membrane
reconstructed biological
reconstructed
fabricating
Prior art date
Application number
BR112018012223-8A
Other languages
English (en)
Other versions
BR112018012223B1 (pt
Inventor
Pellevoisin Christian
Sahuc Florent
Original Assignee
L'oreal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by L'oreal filed Critical L'oreal
Publication of BR112018012223A2 publication Critical patent/BR112018012223A2/pt
Publication of BR112018012223B1 publication Critical patent/BR112018012223B1/pt

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M21/00—Bioreactors or fermenters specially adapted for specific uses
    • C12M21/08—Bioreactors or fermenters specially adapted for specific uses for producing artificial tissue or for ex-vivo cultivation of tissue
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0068—General culture methods using substrates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5029—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell motility
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5082—Supracellular entities, e.g. tissue, organisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2535/00—Supports or coatings for cell culture characterised by topography
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7095—Inflammation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Genetics & Genomics (AREA)
  • Hematology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Toxicology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

a presente invenção está relacionada com membranas contendo, pelo menos dois tipos de porosidade: - uma porosidade de pequena dimensão, mas de alta densidade, que permite o suporte e a nutrição de células de cultura, de forma a obter um modelo de tecido reconstruído, e - uma porosidade de maior dimensão, mas de baixa densidade, que permite a circulação de determinados tipos de células e a passagem de extensões citoplasmáticas de um compartimento para outro.
BR112018012223-8A 2015-12-17 2016-12-19 Membrana de camada única, método de fabricação de uma membrana, dispositivo de cultura celular, método de fabricação de um dispositivo de cultura celular, usos in vitro da membrana, método de preparação de um tecido biológico reconstruído in vitro e uso de um tecido biológico reconstruído in vitro BR112018012223B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1562707A FR3045664A1 (fr) 2015-12-17 2015-12-17 Membrane pour tissu reconstruit comprenant des pores de plusieurs diametres
FR1562707 2015-12-17
PCT/EP2016/081797 WO2017103279A1 (en) 2015-12-17 2016-12-19 Membrane for reconstructed tissue comprising pores of several diameters

Publications (2)

Publication Number Publication Date
BR112018012223A2 true BR112018012223A2 (pt) 2018-11-27
BR112018012223B1 BR112018012223B1 (pt) 2022-05-24

Family

ID=55236794

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018012223-8A BR112018012223B1 (pt) 2015-12-17 2016-12-19 Membrana de camada única, método de fabricação de uma membrana, dispositivo de cultura celular, método de fabricação de um dispositivo de cultura celular, usos in vitro da membrana, método de preparação de um tecido biológico reconstruído in vitro e uso de um tecido biológico reconstruído in vitro

Country Status (7)

Country Link
US (1) US10920184B2 (pt)
EP (1) EP3390615B1 (pt)
JP (1) JP6698844B2 (pt)
CN (1) CN108473930B (pt)
BR (1) BR112018012223B1 (pt)
FR (1) FR3045664A1 (pt)
WO (1) WO2017103279A1 (pt)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113694749A (zh) * 2020-05-21 2021-11-26 杭州科百特科技有限公司 一种大小混合孔径聚合物滤膜及其制备方法以及用途

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2546094A1 (en) * 2004-01-23 2005-08-04 Sumitomo Electric Industries, Ltd. Stretched polytetrafluoroethylene porous article having fine pores formed therein and method for production thereof, and method of ablation machining
JP2007525667A (ja) 2004-02-17 2007-09-06 ヘンケル カーゲーアーアー マイクロ流体分析用デバイス
ATE495238T1 (de) 2005-12-21 2011-01-15 Vaxdesign Corp Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen
FR2895748B1 (fr) 2006-01-05 2008-04-04 Oreal Modele de culture cellulaire et ses applications
CA2641733C (en) * 2006-02-10 2015-03-31 Tengion, Inc. Scaffolds for organ reconstruction and augmentation
US8658851B2 (en) * 2006-10-20 2014-02-25 Keracure, Inc. Devices with cells cultured on flexible supports
CA2713352C (en) 2008-01-10 2018-01-09 Hurel Corporation Immune system modeling devices and methods
EP2394670A1 (en) * 2010-06-04 2011-12-14 Université de Liège Chitosan-based biomimetic scaffolds and methods for preparing the same
US8673628B2 (en) * 2011-06-10 2014-03-18 Essen Instruments, Inc. Methods and apparatus for improving in vitro measurements using boyden chambers
US9200246B2 (en) * 2011-12-01 2015-12-01 Acea Biosciences, Inc. Co-culture device assembly
US20140243354A1 (en) * 2013-02-22 2014-08-28 Galderma Research & Development Snc Combinations of indigo naturalis and berberine and uses thereof
CN104211981A (zh) * 2014-09-11 2014-12-17 北京航空航天大学 一种多级蜂窝状微孔聚合物薄膜自组装成形的方法
JP6612979B2 (ja) 2015-10-28 2019-11-27 チャイナ ウェイファー レベル シーエスピー カンパニー リミテッド イメージセンシングチップのパッケージ構造とパッケージング方法

Also Published As

Publication number Publication date
WO2017103279A1 (en) 2017-06-22
EP3390615A1 (en) 2018-10-24
JP6698844B2 (ja) 2020-05-27
EP3390615B1 (en) 2020-02-26
JP2018537116A (ja) 2018-12-20
BR112018012223B1 (pt) 2022-05-24
CN108473930B (zh) 2022-04-01
US10920184B2 (en) 2021-02-16
CN108473930A (zh) 2018-08-31
FR3045664A1 (fr) 2017-06-23
US20180362912A1 (en) 2018-12-20

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Legal Events

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

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