ATE495238T1 - Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen - Google Patents

Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen

Info

Publication number
ATE495238T1
ATE495238T1 AT06848082T AT06848082T ATE495238T1 AT E495238 T1 ATE495238 T1 AT E495238T1 AT 06848082 T AT06848082 T AT 06848082T AT 06848082 T AT06848082 T AT 06848082T AT E495238 T1 ATE495238 T1 AT E495238T1
Authority
AT
Austria
Prior art keywords
dcs
cultured
transwell
populations
blood monocytes
Prior art date
Application number
AT06848082T
Other languages
English (en)
Inventor
Donald Drake
David Moe
Conan Li
Heather Fahlenkamp
Guzman Sanchez-Schmitz
Russell Higbee
Robert Parkhill
William Warren
Original Assignee
Vaxdesign Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vaxdesign Corp filed Critical Vaxdesign Corp
Application granted granted Critical
Publication of ATE495238T1 publication Critical patent/ATE495238T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4615—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4641—Fungal antigens, e.g. Trichophyton, Aspergillus or Candida
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/20—Material Coatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/28—Vascular endothelial cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Sustainable Development (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT06848082T 2005-12-21 2006-12-21 Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen ATE495238T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75203305P 2005-12-21 2005-12-21
PCT/US2006/049128 WO2007076061A1 (en) 2005-12-21 2006-12-21 A porous membrane device that promotes the differentiation of monocytes into dendritic cells

Publications (1)

Publication Number Publication Date
ATE495238T1 true ATE495238T1 (de) 2011-01-15

Family

ID=37963795

Family Applications (2)

Application Number Title Priority Date Filing Date
AT10151003T ATE531793T1 (de) 2005-12-21 2006-12-21 Eine poröse membran gerät, das die differenzierung von monozyten in dendritische zellen fördert
AT06848082T ATE495238T1 (de) 2005-12-21 2006-12-21 Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT10151003T ATE531793T1 (de) 2005-12-21 2006-12-21 Eine poröse membran gerät, das die differenzierung von monozyten in dendritische zellen fördert

Country Status (9)

Country Link
US (2) US20070178076A1 (de)
EP (2) EP1963491B1 (de)
JP (1) JP2009521228A (de)
AT (2) ATE531793T1 (de)
AU (1) AU2006330951B2 (de)
CA (2) CA2847310A1 (de)
DE (1) DE602006019638D1 (de)
IL (1) IL192090A (de)
WO (1) WO2007076061A1 (de)

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US8298824B2 (en) 2004-04-28 2012-10-30 Sanofi Pasteur Vaxdesign Corporation Methods of evaluating a test agent in a diseased cell model
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US7785883B2 (en) 2004-04-28 2010-08-31 Vax Design Corp. Automatable artificial immune system (AIS)
US7855074B2 (en) 2004-04-28 2010-12-21 Vaxdesign Corp. Artificial immune system: methods for making and use
US7785806B2 (en) 2004-04-28 2010-08-31 Vaxdesign Corporation Method for determining the immunogenicity of an antigen
US7771999B2 (en) 2004-04-28 2010-08-10 Vaxdesign Corp. Disease model incorporation into an artificial immune system (AIS)
AU2006330951B2 (en) * 2005-12-21 2012-04-05 Sanofi Pasteur Vaxdesign Corporation A porous membrane device that promotes the differentiation of monocytes into dendritic cells
US8003387B2 (en) 2005-12-21 2011-08-23 Sanofi Pasteur Vaxdesign Corp. In vitro germinal centers
CA2655344C (en) * 2006-06-27 2016-09-13 Vaxdesign Corporation Models for vaccine assessment
US8647837B2 (en) * 2007-07-16 2014-02-11 Sanofi Pasteur Vaxdesign Corp. Artificial tissue constructs comprising alveolar cells and methods for using the same
US20120171194A1 (en) * 2009-03-17 2012-07-05 Colin Tso Method of Cell Differentiation and Uses Therefor in Screening, Diagnosis and Therapy
US8802747B2 (en) * 2009-08-26 2014-08-12 Molecular Imprints, Inc. Nanoimprint lithography processes for forming nanoparticles
WO2013134464A1 (en) 2012-03-07 2013-09-12 Children's Medical Center Corporation Tissue constructs and uses thereof
US9423234B2 (en) 2012-11-05 2016-08-23 The Regents Of The University Of California Mechanical phenotyping of single cells: high throughput quantitative detection and sorting
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AU2017325009B2 (en) * 2016-09-08 2023-07-20 Sanofi Pasteur Vaxdesign Corp. In vitro neonatal biomimetic (NMIMIC) model and methods of using same
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WO2019002305A1 (en) * 2017-06-26 2019-01-03 BIOHOPE Scientific Solutions for Human Health S.L. METHOD OF PREDICTING AND MONITORING CLINICAL RESPONSE TO IMMUNOMODULATORY THERAPY
CN112221543B (zh) * 2019-07-15 2024-05-10 京东方科技集团股份有限公司 细胞片层转移器件、运输装置和转移细胞片层的方法

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Also Published As

Publication number Publication date
IL192090A (en) 2012-01-31
EP2199384B1 (de) 2011-11-02
JP2009521228A (ja) 2009-06-04
IL192090A0 (en) 2008-12-29
EP1963491B1 (de) 2011-01-12
AU2006330951A1 (en) 2007-07-05
CA2634119A1 (en) 2007-07-05
US20100105135A1 (en) 2010-04-29
AU2006330951B2 (en) 2012-04-05
US20070178076A1 (en) 2007-08-02
WO2007076061A1 (en) 2007-07-05
CA2634119C (en) 2015-02-24
EP1963491A1 (de) 2008-09-03
DE602006019638D1 (de) 2011-02-24
CA2847310A1 (en) 2007-07-05
EP2199384A1 (de) 2010-06-23
ATE531793T1 (de) 2011-11-15

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