ATE531793T1 - Eine poröse membran gerät, das die differenzierung von monozyten in dendritische zellen fördert - Google Patents

Eine poröse membran gerät, das die differenzierung von monozyten in dendritische zellen fördert

Info

Publication number
ATE531793T1
ATE531793T1 AT10151003T AT10151003T ATE531793T1 AT E531793 T1 ATE531793 T1 AT E531793T1 AT 10151003 T AT10151003 T AT 10151003T AT 10151003 T AT10151003 T AT 10151003T AT E531793 T1 ATE531793 T1 AT E531793T1
Authority
AT
Austria
Prior art keywords
dcs
dendritic cells
cultured
monocytes
transwell
Prior art date
Application number
AT10151003T
Other languages
English (en)
Inventor
Donald Drake Iii
David Moe
Conan Li
Heather Fahlenkamp
Guzman Sanchez-Schmitz
Russell Higbee
Robert Parkhill
William Warren
Original Assignee
Sanofi Pasteur Vaxdesign Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Pasteur Vaxdesign Corp filed Critical Sanofi Pasteur Vaxdesign Corp
Application granted granted Critical
Publication of ATE531793T1 publication Critical patent/ATE531793T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/19—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24—Antigen-presenting cells [APC]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K40/00—Cellular immunotherapy
    • A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
    • A61K40/44—Fungal antigens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/20—Material Coatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/28—Vascular endothelial cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Clinical Laboratory Science (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT10151003T 2005-12-21 2006-12-21 Eine poröse membran gerät, das die differenzierung von monozyten in dendritische zellen fördert ATE531793T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US75203305P 2005-12-21 2005-12-21

Publications (1)

Publication Number Publication Date
ATE531793T1 true ATE531793T1 (de) 2011-11-15

Family

ID=37963795

Family Applications (2)

Application Number Title Priority Date Filing Date
AT10151003T ATE531793T1 (de) 2005-12-21 2006-12-21 Eine poröse membran gerät, das die differenzierung von monozyten in dendritische zellen fördert
AT06848082T ATE495238T1 (de) 2005-12-21 2006-12-21 Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT06848082T ATE495238T1 (de) 2005-12-21 2006-12-21 Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen

Country Status (9)

Country Link
US (2) US20070178076A1 (de)
EP (2) EP1963491B1 (de)
JP (1) JP2009521228A (de)
AT (2) ATE531793T1 (de)
AU (1) AU2006330951B2 (de)
CA (2) CA2634119C (de)
DE (1) DE602006019638D1 (de)
IL (1) IL192090A (de)
WO (1) WO2007076061A1 (de)

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US8071373B2 (en) 2004-04-28 2011-12-06 Sanofi Pasteur Vaxdesign Corp. Co-culture lymphoid tissue equivalent (LTE) for an artificial immune system (AIS)
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AU2006331504A1 (en) 2005-12-21 2007-07-05 Vaxdesign Corporation In vitro germinal centers
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EP2409714A1 (de) * 2006-06-27 2012-01-25 Sanofi Pasteur VaxDesign Corporation Modelle für die Bewertung von Impfstoffen
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Also Published As

Publication number Publication date
JP2009521228A (ja) 2009-06-04
WO2007076061A1 (en) 2007-07-05
IL192090A0 (en) 2008-12-29
IL192090A (en) 2012-01-31
DE602006019638D1 (de) 2011-02-24
CA2634119A1 (en) 2007-07-05
EP2199384A1 (de) 2010-06-23
CA2634119C (en) 2015-02-24
CA2847310A1 (en) 2007-07-05
EP1963491A1 (de) 2008-09-03
US20100105135A1 (en) 2010-04-29
EP2199384B1 (de) 2011-11-02
AU2006330951A1 (en) 2007-07-05
EP1963491B1 (de) 2011-01-12
ATE495238T1 (de) 2011-01-15
AU2006330951B2 (en) 2012-04-05
US20070178076A1 (en) 2007-08-02

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