DE602006019638D1 - Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen - Google Patents

Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen

Info

Publication number
DE602006019638D1
DE602006019638D1 DE602006019638T DE602006019638T DE602006019638D1 DE 602006019638 D1 DE602006019638 D1 DE 602006019638D1 DE 602006019638 T DE602006019638 T DE 602006019638T DE 602006019638 T DE602006019638 T DE 602006019638T DE 602006019638 D1 DE602006019638 D1 DE 602006019638D1
Authority
DE
Germany
Prior art keywords
dcs
cultured
transwell
populations
blood monocytes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006019638T
Other languages
English (en)
Inventor
Donald Drake Iii
David Moe
Conan Li
Heather Fahlenkamp
Guzman Sanchez-Schmitz
Russell Higbee
Robert Parkhill
William L Warren
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
VaxDesign Corp
Original Assignee
VaxDesign Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by VaxDesign Corp filed Critical VaxDesign Corp
Publication of DE602006019638D1 publication Critical patent/DE602006019638D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0639—Dendritic cells, e.g. Langherhans cells in the epidermis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/461—Cellular immunotherapy characterised by the cell type used
    • A61K39/4615—Dendritic cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/462—Cellular immunotherapy characterized by the effect or the function of the cells
    • A61K39/4622—Antigen presenting cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/46—Cellular immunotherapy
    • A61K39/464—Cellular immunotherapy characterised by the antigen targeted or presented
    • A61K39/4641—Fungal antigens, e.g. Trichophyton, Aspergillus or Candida
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/20—Material Coatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/14—Scaffolds; Matrices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00—Coculture with; Conditioned medium produced by
    • C12N2502/28—Vascular endothelial cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2503/00—Use of cells in diagnostics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Sustainable Development (AREA)
  • Mycology (AREA)
  • Clinical Laboratory Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hematology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE602006019638T 2005-12-21 2006-12-21 Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen Active DE602006019638D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US75203305P 2005-12-21 2005-12-21
PCT/US2006/049128 WO2007076061A1 (en) 2005-12-21 2006-12-21 A porous membrane device that promotes the differentiation of monocytes into dendritic cells

Publications (1)

Publication Number Publication Date
DE602006019638D1 true DE602006019638D1 (de) 2011-02-24

Family

ID=37963795

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006019638T Active DE602006019638D1 (de) 2005-12-21 2006-12-21 Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen

Country Status (9)

Country Link
US (2) US20070178076A1 (de)
EP (2) EP2199384B1 (de)
JP (1) JP2009521228A (de)
AT (2) ATE495238T1 (de)
AU (1) AU2006330951B2 (de)
CA (2) CA2847310A1 (de)
DE (1) DE602006019638D1 (de)
IL (1) IL192090A (de)
WO (1) WO2007076061A1 (de)

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US7709256B2 (en) * 2004-04-28 2010-05-04 Vaxdesign Corp. Disease model incorporation into an artificial immune system (AIS)
US8071373B2 (en) 2004-04-28 2011-12-06 Sanofi Pasteur Vaxdesign Corp. Co-culture lymphoid tissue equivalent (LTE) for an artificial immune system (AIS)
US7785806B2 (en) 2004-04-28 2010-08-31 Vaxdesign Corporation Method for determining the immunogenicity of an antigen
US8298824B2 (en) 2004-04-28 2012-10-30 Sanofi Pasteur Vaxdesign Corporation Methods of evaluating a test agent in a diseased cell model
US7855074B2 (en) 2004-04-28 2010-12-21 Vaxdesign Corp. Artificial immune system: methods for making and use
US8030070B2 (en) * 2004-04-28 2011-10-04 Sanofi Pasteur Vaxdesign Corp. Artificial lymphoid tissue equivalent
JP5622358B2 (ja) 2005-12-21 2014-11-12 サノフィ パスツール ヴァックスデザインコーポレーション ｉｎｖｉｔｒｏ胚中心
ATE495238T1 (de) * 2005-12-21 2011-01-15 Vaxdesign Corp Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen
AU2007345747A1 (en) * 2006-06-27 2008-08-07 Vaxdesign Corporation Models for vaccine assessment
US8647837B2 (en) * 2007-07-16 2014-02-11 Sanofi Pasteur Vaxdesign Corp. Artificial tissue constructs comprising alveolar cells and methods for using the same
US20120171194A1 (en) * 2009-03-17 2012-07-05 Colin Tso Method of Cell Differentiation and Uses Therefor in Screening, Diagnosis and Therapy
US8802747B2 (en) * 2009-08-26 2014-08-12 Molecular Imprints, Inc. Nanoimprint lithography processes for forming nanoparticles
US10731129B2 (en) 2012-03-07 2020-08-04 Children's Medical Center Corporation Methods of evaluating immunogenicity of an agent using an artificial tissue construct
US9423234B2 (en) 2012-11-05 2016-08-23 The Regents Of The University Of California Mechanical phenotyping of single cells: high throughput quantitative detection and sorting
FR3045664A1 (fr) 2015-12-17 2017-06-23 Oreal Membrane pour tissu reconstruit comprenant des pores de plusieurs diametres
JP2019531717A (ja) * 2016-09-08 2019-11-07 サノフィ パスツール ヴァックスデザイン コーポレーション インビトロの新生児バイオミメティック（ｎｍｉｍｉｃ）モデル及び方法、並びにその使用
KR101986092B1 (ko) * 2016-09-13 2019-06-05 대한뉴팜(주) 유두진피 섬유아세포의 고순도 분리 방법
EP3646026A1 (de) * 2017-06-26 2020-05-06 Biohope Scientific Solutions for Human Health SL Verfahren zur vorhersage und überwachung einer klinischen reaktion auf eine immunmodulatorische therapie
CN112221543B (zh) * 2019-07-15 2024-05-10 京东方科技集团股份有限公司 细胞片层转移器件、运输装置和转移细胞片层的方法

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JP5622358B2 (ja) * 2005-12-21 2014-11-12 サノフィ パスツール ヴァックスデザインコーポレーション ｉｎｖｉｔｒｏ胚中心
ATE495238T1 (de) * 2005-12-21 2011-01-15 Vaxdesign Corp Iin vitro methode um eine potentielle reaktion eines tieres an einen agenten zu bestimmen
AU2007345747A1 (en) * 2006-06-27 2008-08-07 Vaxdesign Corporation Models for vaccine assessment
AU2008275296A1 (en) * 2007-07-06 2009-01-15 Sanofi Pasteur Vaxdesign Corporation Rapid generation of T cell-independent antibody responses to T cell-dependent antigens

Also Published As

Publication number Publication date
IL192090A (en) 2012-01-31
ATE531793T1 (de) 2011-11-15
CA2847310A1 (en) 2007-07-05
WO2007076061A1 (en) 2007-07-05
EP1963491B1 (de) 2011-01-12
US20070178076A1 (en) 2007-08-02
EP2199384A1 (de) 2010-06-23
EP2199384B1 (de) 2011-11-02
ATE495238T1 (de) 2011-01-15
AU2006330951B2 (en) 2012-04-05
CA2634119C (en) 2015-02-24
US20100105135A1 (en) 2010-04-29
IL192090A0 (en) 2008-12-29
CA2634119A1 (en) 2007-07-05
EP1963491A1 (de) 2008-09-03
AU2006330951A1 (en) 2007-07-05
JP2009521228A (ja) 2009-06-04

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