BR112018008209B1 - Métodos para reparo ou inibição ou proteção contra ou prevenção de erosão dentária, promoção da remineralização dentária, e/ou intensificação dos efeitos anticavidade de fluoreto e para produção de um produto para cuidado oral compreendendo proteína anticongelamento, dentifrício, uso de uma proteína anticongelamento, e, composição. - Google Patents
Métodos para reparo ou inibição ou proteção contra ou prevenção de erosão dentária, promoção da remineralização dentária, e/ou intensificação dos efeitos anticavidade de fluoreto e para produção de um produto para cuidado oral compreendendo proteína anticongelamento, dentifrício, uso de uma proteína anticongelamento, e, composição. Download PDFInfo
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- MSLRPWGRFCKNIZ-UHFFFAOYSA-J tetrasodium;hydrogen peroxide;dicarbonate Chemical compound [Na+].[Na+].[Na+].[Na+].OO.OO.OO.[O-]C([O-])=O.[O-]C([O-])=O MSLRPWGRFCKNIZ-UHFFFAOYSA-J 0.000 description 1
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- SYMVZGYNJDKIPL-UHFFFAOYSA-H tricalcium;oxido phosphate Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]OP([O-])([O-])=O.[O-]OP([O-])([O-])=O SYMVZGYNJDKIPL-UHFFFAOYSA-H 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
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- 235000019801 trisodium phosphate Nutrition 0.000 description 1
- VBIJGJLWKWLWHQ-UHFFFAOYSA-K trisodium;oxido phosphate Chemical compound [Na+].[Na+].[Na+].[O-]OP([O-])([O-])=O VBIJGJLWKWLWHQ-UHFFFAOYSA-K 0.000 description 1
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- 241000701161 unidentified adenovirus Species 0.000 description 1
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- AQLJVWUFPCUVLO-UHFFFAOYSA-N urea hydrogen peroxide Chemical compound OO.NC(N)=O AQLJVWUFPCUVLO-UHFFFAOYSA-N 0.000 description 1
- 235000012141 vanillin Nutrition 0.000 description 1
- MWOOGOJBHIARFG-UHFFFAOYSA-N vanillin Chemical compound COC1=CC(C=O)=CC=C1O MWOOGOJBHIARFG-UHFFFAOYSA-N 0.000 description 1
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- 150000003722 vitamin derivatives Chemical class 0.000 description 1
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- 238000010792 warming Methods 0.000 description 1
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- LRXTYHSAJDENHV-UHFFFAOYSA-H zinc phosphate Chemical compound [Zn+2].[Zn+2].[Zn+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O LRXTYHSAJDENHV-UHFFFAOYSA-H 0.000 description 1
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Images
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/20—Halogens; Compounds thereof
- A61K8/21—Fluorides; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
- A61K9/0058—Chewing gums
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Chemical & Material Sciences (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Inorganic Chemistry (AREA)
- Cosmetics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Peptides Or Proteins (AREA)
- Confectionery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562246163P | 2015-10-26 | 2015-10-26 | |
| US62/246,163 | 2015-10-26 | ||
| PCT/EP2016/075649 WO2017072104A1 (en) | 2015-10-26 | 2016-10-25 | Oral care products and methods comprising antifreeze proteins |
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| BR112018008209A2 BR112018008209A2 (pt) | 2018-10-30 |
| BR112018008209B1 true BR112018008209B1 (pt) | 2021-12-14 |
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| Application Number | Title | Priority Date | Filing Date |
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| BR112018008209-0A BR112018008209B1 (pt) | 2015-10-26 | 2016-10-25 | Métodos para reparo ou inibição ou proteção contra ou prevenção de erosão dentária, promoção da remineralização dentária, e/ou intensificação dos efeitos anticavidade de fluoreto e para produção de um produto para cuidado oral compreendendo proteína anticongelamento, dentifrício, uso de uma proteína anticongelamento, e, composição. |
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|---|---|
| US (2) | US10507340B2 (ko) |
| EP (1) | EP3368002B1 (ko) |
| JP (2) | JP7019567B2 (ko) |
| KR (1) | KR20180069058A (ko) |
| CN (1) | CN108348438B (ko) |
| BR (1) | BR112018008209B1 (ko) |
| MX (1) | MX2018005201A (ko) |
| RU (1) | RU2750748C2 (ko) |
| WO (1) | WO2017072104A1 (ko) |
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| EP3368002B1 (en) | 2015-10-26 | 2021-10-06 | Basf Se | Oral care products and methods comprising anitfreeze proteins |
| AU2018257898A1 (en) * | 2017-04-24 | 2019-10-31 | Basf Se | Oral care products and methods |
| CN112661825A (zh) * | 2020-12-29 | 2021-04-16 | 华中科技大学同济医学院附属协和医院 | 一种生物冷冻保护剂及其制备方法和应用 |
| US11607381B2 (en) | 2021-04-19 | 2023-03-21 | Imam Abdulrahman Bin Faisal University | Remineralization of teeth using Brazilian green propolis |
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| JP4257970B2 (ja) | 2002-03-15 | 2009-04-30 | 独立行政法人産業技術総合研究所 | 担子菌類の産生する不凍タンパク質 |
| JP2004000019A (ja) * | 2002-03-27 | 2004-01-08 | Ikeda Shokken Kk | 変性防止剤および液体組成物 |
| WO2004022081A1 (de) | 2002-09-07 | 2004-03-18 | Beiersdorf Ag | Kosmetische oder dermatologische zubereitungen mit einem gehalt an anti-freezing proteinen und/oder anti-freezing glycoproteinen |
| ES2399345T3 (es) | 2005-06-07 | 2013-03-27 | The University Of Melbourne | Mineralización dental |
| JP5171752B2 (ja) * | 2009-07-23 | 2013-03-27 | 株式会社ノエビア | 皮膚外用剤 |
| CN102108357B (zh) | 2009-12-24 | 2013-09-11 | 上海市农业科学院 | 源于昆虫抗冻肽基因及其制备方法和应用 |
| JP2011229504A (ja) * | 2010-04-30 | 2011-11-17 | National Institute Of Advanced Industrial Science & Technology | 生産性および不凍活性を向上させた改変型不凍タンパク質とその製造方法 |
| EP2565200B1 (en) * | 2010-04-30 | 2017-10-11 | Kaneka Corporation | Antifreeze protein |
| EP2409682A1 (en) * | 2010-07-19 | 2012-01-25 | Werner E. G. MÜLLER | Hydroxyapatite-binding nano- and microparticles for caries prophylaxis and reduction of dental hypersensitivity |
| WO2012023486A1 (ja) | 2010-08-16 | 2012-02-23 | 株式会社カネカ | 氷結晶化阻害タンパク質 |
| JPWO2012026596A1 (ja) * | 2010-08-26 | 2013-10-28 | 株式会社ニチレイフーズ | 熱ヒステリシス活性増加方法、熱ヒステリシス活性の熱失活の低減方法、及び熱ヒステリシス活性増加用組成物 |
| JP2014517693A (ja) * | 2011-05-27 | 2014-07-24 | ザ ユニバーシティ オブ ワシントン スルー イッツ センター フォー コマーシャライゼーション | 歯科疾患を治療するための試薬および方法 |
| EP3368002B1 (en) | 2015-10-26 | 2021-10-06 | Basf Se | Oral care products and methods comprising anitfreeze proteins |
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2016
- 2016-10-25 EP EP16790542.1A patent/EP3368002B1/en active Active
- 2016-10-25 WO PCT/EP2016/075649 patent/WO2017072104A1/en active Application Filing
- 2016-10-25 CN CN201680062481.6A patent/CN108348438B/zh active Active
- 2016-10-25 MX MX2018005201A patent/MX2018005201A/es unknown
- 2016-10-25 RU RU2018119340A patent/RU2750748C2/ru active
- 2016-10-25 KR KR1020187014905A patent/KR20180069058A/ko not_active Application Discontinuation
- 2016-10-25 JP JP2018521245A patent/JP7019567B2/ja active Active
- 2016-10-25 US US15/770,978 patent/US10507340B2/en active Active
- 2016-10-25 BR BR112018008209-0A patent/BR112018008209B1/pt active IP Right Grant
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2019
- 2019-12-16 US US16/715,273 patent/US10898739B2/en active Active
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2021
- 2021-10-29 JP JP2021177760A patent/JP2022031667A/ja not_active Withdrawn
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| US10507340B2 (en) | 2019-12-17 |
| RU2750748C2 (ru) | 2021-07-02 |
| US20200114177A1 (en) | 2020-04-16 |
| JP2018531276A (ja) | 2018-10-25 |
| RU2018119340A (ru) | 2019-12-02 |
| BR112018008209A2 (pt) | 2018-10-30 |
| WO2017072104A1 (en) | 2017-05-04 |
| EP3368002A1 (en) | 2018-09-05 |
| KR20180069058A (ko) | 2018-06-22 |
| US20190022429A1 (en) | 2019-01-24 |
| JP2022031667A (ja) | 2022-02-22 |
| CN108348438A (zh) | 2018-07-31 |
| EP3368002B1 (en) | 2021-10-06 |
| JP7019567B2 (ja) | 2022-02-15 |
| US10898739B2 (en) | 2021-01-26 |
| CN108348438B (zh) | 2021-07-13 |
| MX2018005201A (es) | 2018-07-06 |
| RU2018119340A3 (ko) | 2020-04-28 |
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Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 25/10/2016, OBSERVADAS AS CONDICOES LEGAIS. |