BR112018003852B1 - Métodos, método para calibrar ou recalibrar um primeiro dispositivo, método de operação de um tanque, método para determinar os efeitos de deslocamento de ph, unidades de comparação e sistema - Google Patents

Métodos, método para calibrar ou recalibrar um primeiro dispositivo, método de operação de um tanque, método para determinar os efeitos de deslocamento de ph, unidades de comparação e sistema Download PDF

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BR112018003852B1
BR112018003852B1 BR112018003852-0A BR112018003852A BR112018003852B1 BR 112018003852 B1 BR112018003852 B1 BR 112018003852B1 BR 112018003852 A BR112018003852 A BR 112018003852A BR 112018003852 B1 BR112018003852 B1 BR 112018003852B1
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medium
value
tank
concentration
measuring device
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BR112018003852-0A
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English (en)
Portuguese (pt)
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BR112018003852A2 (pt
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Detlef Eisenkraetzer
Christian Klinger
Katrin Greppmair
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F. Hoffmann-La Roche Ag
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Publication of BR112018003852A2 publication Critical patent/BR112018003852A2/pt
Publication of BR112018003852B1 publication Critical patent/BR112018003852B1/pt

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/26Means for regulation, monitoring, measurement or control, e.g. flow regulation of pH
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/34Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48Automatic or computerized control
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01DMEASURING NOT SPECIALLY ADAPTED FOR A SPECIFIC VARIABLE; ARRANGEMENTS FOR MEASURING TWO OR MORE VARIABLES NOT COVERED IN A SINGLE OTHER SUBCLASS; TARIFF METERING APPARATUS; MEASURING OR TESTING NOT OTHERWISE PROVIDED FOR
    • G01D18/00Testing or calibrating apparatus or arrangements provided for in groups G01D1/00 - G01D15/00
    • G01D18/008Testing or calibrating apparatus or arrangements provided for in groups G01D1/00 - G01D15/00 with calibration coefficients stored in memory
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416Systems
    • G01N27/4163Systems checking the operation of, or calibrating, the measuring apparatus
    • G01N27/4165Systems checking the operation of, or calibrating, the measuring apparatus for pH meters
    • GPHYSICS
    • G05CONTROLLING; REGULATING
    • G05DSYSTEMS FOR CONTROLLING OR REGULATING NON-ELECTRIC VARIABLES
    • G05D21/00Control of chemical or physico-chemical variables, e.g. pH value
    • G05D21/02Control of chemical or physico-chemical variables, e.g. pH value characterised by the use of electric means

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Automation & Control Theory (AREA)
  • Computer Hardware Design (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Testing Or Calibration Of Command Recording Devices (AREA)
BR112018003852-0A 2015-10-30 2016-10-28 Métodos, método para calibrar ou recalibrar um primeiro dispositivo, método de operação de um tanque, método para determinar os efeitos de deslocamento de ph, unidades de comparação e sistema BR112018003852B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP15192389 2015-10-30
EP15192389.3 2015-10-30
PCT/EP2016/076173 WO2017072346A1 (en) 2015-10-30 2016-10-28 Identification of calibration deviations of ph-measuring devices

Publications (2)

Publication Number Publication Date
BR112018003852A2 BR112018003852A2 (pt) 2018-10-02
BR112018003852B1 true BR112018003852B1 (pt) 2021-12-14

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BR112018003852-0A BR112018003852B1 (pt) 2015-10-30 2016-10-28 Métodos, método para calibrar ou recalibrar um primeiro dispositivo, método de operação de um tanque, método para determinar os efeitos de deslocamento de ph, unidades de comparação e sistema

Country Status (15)

Country Link
US (3) US11371006B2 (enExample)
EP (2) EP3786278B1 (enExample)
JP (1) JP6893208B2 (enExample)
KR (1) KR102612135B1 (enExample)
CN (1) CN108368471B (enExample)
AU (1) AU2016345668B2 (enExample)
BR (1) BR112018003852B1 (enExample)
CA (1) CA2996468A1 (enExample)
ES (2) ES2808923T3 (enExample)
HR (2) HRP20221081T1 (enExample)
IL (1) IL258080B (enExample)
MX (1) MX2018004248A (enExample)
PL (2) PL3368653T3 (enExample)
SI (2) SI3786278T1 (enExample)
WO (1) WO2017072346A1 (enExample)

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DE102019107625A1 (de) * 2018-12-20 2020-06-25 Endress+Hauser Conducta Gmbh+Co. Kg Verfahren zur In-Prozess-Justage eines potentiometrischen Sensors einer Messanordnung
CN109856220B (zh) * 2019-03-07 2020-06-05 中南大学 一种pH值在线检测装置及其控制和校准预判方法
CN110057990B (zh) * 2019-03-08 2021-09-14 天津大学 一种多参数水质剖面仪的pH校正方法
US12031941B2 (en) * 2019-08-12 2024-07-09 Emd Millipore Corporation Methods to automatically calibrate pH sensors without sampling
IL305067A (en) * 2021-02-12 2023-10-01 Bayer Healthcare Llc Methods for adjusting the pH of cell culture medium
EP4612312A1 (en) 2022-11-02 2025-09-10 F. Hoffmann-La Roche AG Method for producing glycoprotein compositions
CN115753948B (zh) * 2022-11-28 2025-07-25 新疆大学 一种高温高压条件下饱和酸性气体的溶液pH获取系统、方法及预测方法
US20240248104A1 (en) * 2023-01-24 2024-07-25 Culture Biosciences, Inc. Methods and systems for tracking performance characteristics of probes for a biomanufacturing system
WO2025224236A1 (en) 2024-04-25 2025-10-30 F. Hoffmann-La Roche Ag Methods and systems for determining an actual ph in a liquid phase of a tank

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JPS60141286A (ja) 1983-12-28 1985-07-26 Ajinomoto Co Inc 動物細胞の培養方法および装置
US4513280A (en) 1984-10-04 1985-04-23 The United States Of America As Represented By The Secretary Of The Navy Method and apparatus for the detection of toxicants
JPH06174677A (ja) * 1992-12-08 1994-06-24 Meidensha Corp 酸−アルカリ滴定法におけるpH計の誤差検出方法及び装置
AT401111B (de) * 1995-02-01 1996-06-25 Avl Verbrennungskraft Messtech Verfahren zur kalibrierung eines ph-messelementes
US5578194A (en) * 1995-03-10 1996-11-26 Nova Biomedical Corporation Calibration of electrodes
CH690251A5 (de) * 1995-11-10 2000-06-15 Hamilton Bonaduz Ag Luftstabile pH-Standardlösungen.
DE69807042T2 (de) * 1997-01-17 2003-02-06 Metracor Technologies Inc., San Diego Verfahren zum kalibrieren von sensoren in diagnostischen testverfahren
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DE10239610B3 (de) 2002-08-29 2004-06-24 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Verfahren zur Funktionsüberwachung von Sensoren
CN1238498C (zh) 2004-02-12 2006-01-25 陈志南 动物细胞无血清悬浮培养工艺过程控制参数的方法
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JP5136280B2 (ja) * 2007-08-24 2013-02-06 Toto株式会社 腸内状態測定装置および測定方法
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Also Published As

Publication number Publication date
HK1258706A1 (zh) 2019-11-15
SI3368653T1 (sl) 2020-08-31
IL258080B (en) 2021-05-31
JP6893208B2 (ja) 2021-06-23
PL3368653T3 (pl) 2020-10-19
HRP20221081T1 (hr) 2022-11-25
HRP20201130T1 (hr) 2020-10-30
PL3786278T3 (pl) 2022-09-19
MX2018004248A (es) 2018-05-15
US11866686B2 (en) 2024-01-09
AU2016345668A1 (en) 2018-03-08
ES2808923T3 (es) 2021-03-02
EP3786278A1 (en) 2021-03-03
EP3786278B1 (en) 2022-07-13
BR112018003852A2 (pt) 2018-10-02
AU2016345668B2 (en) 2021-07-08
CA2996468A1 (en) 2017-05-04
CN108368471A (zh) 2018-08-03
ES2926594T3 (es) 2022-10-27
CN108368471B (zh) 2022-07-15
US20220325223A1 (en) 2022-10-13
KR102612135B1 (ko) 2023-12-08
WO2017072346A1 (en) 2017-05-04
KR20180077161A (ko) 2018-07-06
EP3368653B1 (en) 2020-05-27
US20240132829A1 (en) 2024-04-25
SI3786278T1 (sl) 2022-10-28
IL258080A (en) 2018-05-31
US20180216059A1 (en) 2018-08-02
JP2018534560A (ja) 2018-11-22
EP3368653A1 (en) 2018-09-05
US11371006B2 (en) 2022-06-28

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B06U Preliminary requirement: requests with searches performed by other patent offices: procedure suspended [chapter 6.21 patent gazette]
B09A Decision: intention to grant [chapter 9.1 patent gazette]
B09W Correction of the decision to grant [chapter 9.1.4 patent gazette]

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