BR112018003779A2 - sialil-di-lewis a conforme expresso em glicoproteínas, mas não glicolipídios, como um alvo de câncer funcional e anticorpos para o mesmo - Google Patents

sialil-di-lewis a conforme expresso em glicoproteínas, mas não glicolipídios, como um alvo de câncer funcional e anticorpos para o mesmo

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Publication number
BR112018003779A2
BR112018003779A2 BR112018003779-6A BR112018003779A BR112018003779A2 BR 112018003779 A2 BR112018003779 A2 BR 112018003779A2 BR 112018003779 A BR112018003779 A BR 112018003779A BR 112018003779 A2 BR112018003779 A2 BR 112018003779A2
Authority
BR
Brazil
Prior art keywords
sialyl
glycolipids
glycoproteins
lewis
antibodies
Prior art date
Application number
BR112018003779-6A
Other languages
English (en)
Portuguese (pt)
Inventor
Gillian Durrant Lindy
Vankemmelbeke Mireille
Tivadar Silvana
Parsons Tina
Mcintosh Richard
Original Assignee
The University Of Nottingham
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The University Of Nottingham filed Critical The University Of Nottingham
Publication of BR112018003779A2 publication Critical patent/BR112018003779A2/pt

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BR112018003779-6A 2015-08-25 2016-08-25 sialil-di-lewis a conforme expresso em glicoproteínas, mas não glicolipídios, como um alvo de câncer funcional e anticorpos para o mesmo BR112018003779A2 (pt)

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GBGB1515094.9A GB201515094D0 (en) 2015-08-25 2015-08-25 Sialyl-di-lewis a as expressed on glycoproteins but not glycolipids as a functional cancer target and antibodies thereto
GB1515094.9 2015-08-25
PCT/GB2016/052647 WO2017033020A1 (en) 2015-08-25 2016-08-25 Sialyl-di-lewis a as expressed on glycoproteins but not glycolipids as a functional cancer target and antibodies thereto

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LT3041507T (lt) * 2013-08-26 2021-08-25 Biontech Research And Development, Inc. Nukleorūgštys, koduojančios antikūnus prieš sialil-lewis a
JP7672340B2 (ja) * 2018-10-19 2025-05-07 メモリアル スローン ケタリング キャンサー センター シアリルルイスaを標的とするキメラ抗原受容体およびその使用
GB201910899D0 (en) * 2019-07-31 2019-09-11 Scancell Ltd Binding members
GB201910900D0 (en) 2019-07-31 2019-09-11 Scancell Ltd Modified fc-regions to enhance functional affinity of antibodies and antigen binding fragments thereof
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LT3041507T (lt) 2013-08-26 2021-08-25 Biontech Research And Development, Inc. Nukleorūgštys, koduojančios antikūnus prieš sialil-lewis a
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